Clinics of oncology最新文献

{"title":"Management of Anal Adenocarcinoma in Italy: National Survey by the Italian Association of Radiotherapy and Clinical Oncology (AIRO) Gastrointestinal Tumors Study Group","authors":"Pittoni P, Franco P, Caravatta L, Chiloiro G, Gambacorta MA, Genovesi D, Lupattelli M, Mantello G, Montesi G, Montrone S, Valvo F, Scandolaro L","doi":"10.47829/coo.2023.62401","DOIUrl":"https://doi.org/10.47829/coo.2023.62401","url":null,"abstract":"Aims: Anal canal adenocarcinoma is a rare neoplasm and there is currently no consensus on optimal management. Indeed, some clinical studies support trimodal therapy","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85085609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small Extracellular Vesicles and Survivin as Diagnostic and Prognostic Marker for Breast Cancer: A Pilot Study","authors":"Novais Aa, Costa Ds, Neves Gml, Zukeran Ll, Lopes Bo, de Godoy BLV2, Ferronato Ga, Rosa Pms, da Silveira JC, Tamarindo Gh, Chuffa Lga, Júnior Nab, Bracha S, Zuccari Dapc","doi":"10.47829/coo.2023.62202","DOIUrl":"https://doi.org/10.47829/coo.2023.62202","url":null,"abstract":"","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77912482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Implementation of New Online Strategies That Increase Physical Activity Behaviour in Cancer Patients","authors":"SC Barrio, LG Herrero, MC Montealegre, Torre Jdl, MP Santamaría, L. Gil","doi":"10.47829/coo.2023.62601","DOIUrl":"https://doi.org/10.47829/coo.2023.62601","url":null,"abstract":"levels in cancer patients during and after the lockdown","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82988042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analytical Dosimetric Study of Postoperative Brachytherapy and Electron Beam Irradiation in the Treatment of Complex Keloids","authors":"Peng Jl, Mcdonald Dg, Maynard Mr, Rapchak Ak, Godwin Wj, Roles Sa, Cooper Sl","doi":"10.47829/coo.2023.62101","DOIUrl":"https://doi.org/10.47829/coo.2023.62101","url":null,"abstract":"","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84719251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Kidney Injury in Patients with Leukaemia Submitted to Allogeneic Hematopoietic Stem Cell Transplant – KDIGO Classification with Creatinine and Urinary Output Criteria: Cohort Analysis","authors":"Rodrigues N, C. C, Branco C, M. F, Vasconcelos P, M. C, Papoila Al, Pinto I, Lopes Ja","doi":"10.47829/coo.2023.61801","DOIUrl":"https://doi.org/10.47829/coo.2023.61801","url":null,"abstract":"Background: Allogeneic Hematopoietic Stem Cell Transplant (allo-HSCT) is often complicated by Acute Kidney Injury (AKI) and has been increasingly used in patients with leukaemia. Studies on this subject include patients with several haematological diseases and use only Serum Creatinine (SCr) to define AKI. We aimed to evaluate incidence, risk factors and 5-year prognostic impact of AKI in patients with leukaemia submitted to allo-HSCT by SCr and Urinary Output (UO). Methods: We conducted a single-centre retrospective cohort study. AKI was defined according to KDIGO classification. We used survival analysis methods considering competing events - the Fine and Gray method - to identify AKI risk factors and assess the impact of AKI on disease-free survival. Additive Cox proportional hazards regression models were applied to analyse time until death from all causes. Stepwise selection regression methods were used to create the final multivariable model. Results: We included 164 patients. The cumulative incidence of AKI was 63.4% 100 days post-HSCT. On the first day of AKI, 76.9% presented SCr criteria, 15.4% presented UO criteria and 7.7% presented both criteria. The highest stage of AKI was 1 in 61.8%, 2 in 21.6% and 3 in 16.7%. Variables independently associated with AKI: HCT-CI >2 (HR:1.88,95%CI:1.13- 3.11;p=0.015), radiotherapy in the past (HR:2.07,95%CI:2.07- 1.06;p=0.034), LDH at hospital admission (HR:1.51,95%CI:1.03- 2.21;p=0.035), shock (HR:1.57,95%CI:1.02-2.39;p=0.039), and sepsis (HR:3.36,95%CI:1.22-9.24;p=0.019). Severe AKI was independently associated with lower overall survival along the first 5 years (HR:1.76,95%CI:1.03-3.00;p=0.037). Conclusion: AKI in leukaemia patients submitted to allo-HSCT had a cumulative incidence of 63.4% and more than 15% of these patients presented only with UO reduction on the day of AKI onset. Two thirds of the patients evolved with AKI stage 2 or 3. Sepsis, previous radiotherapy treatments at any time before HSCT, HCT-CI scoring higher than 2 points, shock and higher LDH levels increased the risk of developing AKI. Severe AKI was associated to lower overall survival throughout the first five years after allo-HSCT. To our knowledge, this is the first study considering both SCr and UO for AKI patients with Leukaemia submitted to allogeneic Hematopoietic Stem Cell Transplant.","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75266840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Activity Levels and Health Quality of Life in Spanish Young Adults with Cancer Prior to and after Cancer Diagnosis","authors":"None Castellanos-Montealegre M, None Brunet J, None Collado NR, None Coll VG, None Gil-Herrero L, None López-Tarruella S, None Montealegre M, None Cerezo S, None Fernández A, None Ruiz A, None Casla-Barrio S","doi":"10.47829/coo.2023.7102","DOIUrl":"https://doi.org/10.47829/coo.2023.7102","url":null,"abstract":"1.1. Purpose: To understand how healthy lifestyle behaviors patterns change across key phases of the disease in young adults. The main purposes were to evaluate change in minutes of physical activity in young adults with cancer across two timepoints: prior to and after cancer diagnosis, and to assess physical activity habits and HrQOL across the two timepoints","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135497036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Validation and Quantitative Evaluation of a Novel Artificial-Intelligence Automatic Segmentation Tool in Radiotherapy Planning","authors":"Peng Jl","doi":"10.47829/coo.2023.61301","DOIUrl":"https://doi.org/10.47829/coo.2023.61301","url":null,"abstract":"higher than 0.90 for all OARs except the esophagus (mean DSC 0.83 ± 0.09)). Mean DSC values ranged from 0.98 ± 0.01 to 0.83 ± 0.09, while the DTAmean ranged from 0.68 ± 0.3 to 0.84 +0.54 mm to mm. HD values ranged from 9.88±15.99 mm to 25.61±8.78 mm. For all body sites, the AI-AS system was able to generate a full set of contours in approximately 2 minutes, while manual contouring of these structures required approximately 30 minutes.","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74277302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gamma Knife Radiosurgery; A Dependable Safe and Effective Option for Glomus Jagulare Tumors Control: A Single Institution Long-Term Experience and Review of the Literature","authors":"Hafez Rfa, Morgan Ms, Kawy Eae, Fahmy Om, Hassan Ht, Zakaria Wk","doi":"10.47829/coo.2023.61901","DOIUrl":"https://doi.org/10.47829/coo.2023.61901","url":null,"abstract":"","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87976642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adrenocortical Carcinoma in a 2 Years Old Girl, a Rare Cause of Clitoridomegaly: A Case Report","authors":"None Léonidas N, None Omid M, None Helle M, None Kabirou M, None Diori A, None Issoufou Y, None Efared B, None Aminou M, None Habibou A","doi":"10.47829/coo.2023.7301","DOIUrl":"https://doi.org/10.47829/coo.2023.7301","url":null,"abstract":"","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135212846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Review and Meta-Analysis on Colorectal Cancer Found on Colonic Evaluation after CT-Confirmed Acute Diverticulitis in the Asian Population","authors":"Chang JHE, None Koo CH, None Syn NL, None Wee IJY, None Mathew R","doi":"10.47829/coo.2023.7304","DOIUrl":"https://doi.org/10.47829/coo.2023.7304","url":null,"abstract":"cancer”, “colonic cancer”,","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135212347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}