Clinics of oncology最新文献_第5页

A Patient with Gastric Metastasis of Lobular Breast Cancer with CDH1 Mutation: A Case Report 伴有CDH1突变的小叶型乳腺癌胃转移1例

Clinics of oncology Pub Date : 2020-01-01 DOI: 10.47829/coo.2020.3305

H. Wang, Z. Li, H. Zhang, Z. Yang, Jian-Yun Nie

引用次数: 0

The Role of Photodynamic Therapy (PDT) in Treating Early Esophageal Cancer: The Long-Term Results and Comparison with Esophagectomy 光动力疗法(PDT)在早期食管癌治疗中的作用:长期疗效及与食管切除术的比较

Clinics of oncology Pub Date : 2020-01-01 DOI: 10.47829/coo.2020.3202

Huang Yh, Chen Kc, Yang Pw, Lin Mw, Huang Pm, Kuo Sw, Lee Jm

引用次数: 2

Racial Differences in Accepting Pegfilgrastim Onpro Kit (On-Body Injector) Use Among Cancer Patients. 癌症患者接受Pegfilgrastim Onpro试剂盒（体内注射器）使用的种族差异。

Clinics of oncology Pub Date : 2019-01-01 Epub Date: 2019-02-25

M W Saif, D W Hackenyos, M H Smith, P Healey, V Relias, K Wasif

{"title":"Racial Differences in Accepting Pegfilgrastim Onpro Kit (On-Body Injector) Use Among Cancer Patients.","authors":"M W Saif, D W Hackenyos, M H Smith, P Healey, V Relias, K Wasif","doi":"","DOIUrl":"","url":null,"abstract":"Background: 1.1.Neulasta Onpro kit eliminates need for additional clinic visit after chemotherapy. Given the racially diverse population in our institution, we investigated acceptance of Onpro kit among patients on chemotherapy.Research design and methods: 1.2.Single-institution, retrospective review conducted in patients with GI tumors who received Onpro kit within 1 hour of completion of systemic chemotherapy from Jan 2014 through Jan 2018. Clinic/nursing notes and pharmacy records were reviewed to identify patients who refused Onpro kit and to discern reasons for refusal, including racial reason.Results: 1.3.Total 238 orders for kit were voided amongst 68 patients (Caucasian 41; African American 7; Spanish 3; Asian 17). Overall, 15/68 patients refused kit (22%) of these 87% were Asian. The reasons for refusal included dislike of bulky attachment to skin, request to place kit on stomach instead of arm, trepidation over unwitnessed administration of drug, fear of reaction, disposal at home, fear of pain, lack of confirmation of proper dose administration, and need for MRI.Conclusions: 1.4.While Onpro kit is an attractive alternative, 22% of patients with voided orders, mainly of Asian race, declined its application. We believe the current study represents the first look at important racial differences in accepting Onpro kit. Consideration of patients' cultural heritage, race, ethnicity and education may facilitate communication between physicians and patients to achieve optimal cancer care.","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"1 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690622/pdf/nihms-1035558.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41223279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Possible Impact of a European Agency for the Strategic Management Against Cancer (EASMAC) on Treatment, Diagnosis and EU Politics 欧洲癌症战略管理机构(EASMAC)对治疗、诊断和欧盟政治的可能影响

Clinics of oncology Pub Date : 1900-01-01 DOI: 10.47829/coo.2020.3201

C. Melidis

引用次数: 0

Upper Rectal Cancer: Benefit After Preoperative Chemoradiation Versus Upfront Surgery? 上直肠癌:术前放化疗与术前手术的益处?

Clinics of oncology Pub Date : 1900-01-01 DOI: 10.47829/coo.2022.6102

M. Lutsyk, M. Caro, B. Gutiérrez, I. Turgeman, Gabriela Antel, I. Planas, Y. Luis, E. Luguera, S. Villà

{"title":"Upper Rectal Cancer: Benefit After Preoperative Chemoradiation Versus Upfront Surgery?","authors":"M. Lutsyk, M. Caro, B. Gutiérrez, I. Turgeman, Gabriela Antel, I. Planas, Y. Luis, E. Luguera, S. Villà","doi":"10.47829/coo.2022.6102","DOIUrl":"https://doi.org/10.47829/coo.2022.6102","url":null,"abstract":"Purpose: Upper rectal cancer management is controversial. The present series reports the outcomes of treatment comparing neoadjuvant chemoradiation (NCRT) versus upfront surgery. 1.2. Methods and materials: In this retrospective study we enrolled patients with upper rectal or sigmoid junction locally advanced tumors (stages II-III). At the first Institution patients received NCRT followed by surgery (study group); at the second Institution patients were referred to upfront surgery (control group). Overall survival was the main endpoint of the analysis. Local relapse and other clinical variables were also analyzed. 1.3. Results: Fifty patients in the study group and 32 patients in the control group were analyzed. In the NCRT group there were more N-positive patients (p<0.001); T-stage was similar for both groups. All surgical procedures were performed with R0 margins. Among NCRT patients, in seven cases (14%) complete pathologic response was found. In 27 cases (54%) downstaging in T-stage was achieved. Comparing OS between NCRT and control group there was no significant difference at five years: 84% for NCRT group and 79% for control group (p 0.37). In univariate analysis, clinical T-stage had a statistically significant impact on survival. Patients with cT3 disease did better than patients with cT4 (p = 0.014). Two cases of G4 toxicity were observed and only one case of local relapse was observed in NCRT group. 1.4. Conclusion: NCRT achieved a high rate of downstaging alongside tolerable toxicity profile, but did not affect survival outcome in this selected group, as compared to surgery alone.","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88798798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0