{"title":"A Patient with Gastric Metastasis of Lobular Breast Cancer with CDH1 Mutation: A Case Report","authors":"H. Wang, Z. Li, H. Zhang, Z. Yang, Jian-Yun Nie","doi":"10.47829/coo.2020.3305","DOIUrl":null,"url":null,"abstract":"Gastric metastasis of breast cancer is extremely rare, diagnosed as breast cancer metastases to the stomach should distinguish between primary and metastatic tumors because of their differences in prognosis and management. Mutations in the CDH1 gene may increase the risk of this pathogenesis since E-cadherin plays a cru-cial role in both lobular breast cancer and gastric cancer.","PeriodicalId":92766,"journal":{"name":"Clinics of oncology","volume":"147 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinics of oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47829/coo.2020.3305","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Gastric metastasis of breast cancer is extremely rare, diagnosed as breast cancer metastases to the stomach should distinguish between primary and metastatic tumors because of their differences in prognosis and management. Mutations in the CDH1 gene may increase the risk of this pathogenesis since E-cadherin plays a cru-cial role in both lobular breast cancer and gastric cancer.