{"title":"Specific intracellular Ca2+ signal in hepatocytes after 70% partial hepatectomy in rats","authors":"Z. Taira, Hiroshi Monmasu, Y. Ueda","doi":"10.15761/pmrr.1000221","DOIUrl":"https://doi.org/10.15761/pmrr.1000221","url":null,"abstract":"New intracellular Ca 2+ signal consisting of two successive peaks in hepatocytes is found during liver regeneration after 70% partial hepatectomy in rats [1,2].","PeriodicalId":92704,"journal":{"name":"Physical medicine and rehabilitation research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67509026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Probable causes of blood clotting driven by SARS-CoV-2","authors":"Mohammad Safiuddin","doi":"10.15761/pmrr.1000222","DOIUrl":"https://doi.org/10.15761/pmrr.1000222","url":null,"abstract":"Coronavirus Disease 2019 (COVID-19) has transmitted almost all over the world after evolving from Wuhan, China in December 2019. The World Health Organization (WHO) declared COVID-19 outbreak a pandemic on March 11, 2020 [1]. COVID-19 is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) [2,3], which transfers from an infected person to a susceptible person via direct contact (e.g., handshaking, hugging) or indirect contact through touching materials or objects that are contaminated by an infected person (e.g., doorknob, handrail, paper tissue) [4,5]. It can also spread via airborne route (i.e., through aerosols created by expiratory activities) [6,7], which is a real concern. SARS-CoV-2 is a nanosized virus. It varies from 65 to 125 nm [8]. Having such a small size, SARSCoV-2 could likely be spread in airborne route.","PeriodicalId":92704,"journal":{"name":"Physical medicine and rehabilitation research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67509523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spinal segmental sensitization as a common origin of chronic non-specific regional musculoskeletal pain: review of its pathophysiology and diagnosis","authors":"Tomas Nakazato, P. Romero, M. Guzzardo","doi":"10.15761/pmrr.1000223","DOIUrl":"https://doi.org/10.15761/pmrr.1000223","url":null,"abstract":"Musculoskeletal pain involving a region of the spine with radiation to the head, trunk, or extremities is relatively common in daily medical practice, such as upper- neck pain with headache, lower-neck pain and discomfort in the shoulders and arms, or low-back pain with sciatica. The instability of a vertebral segment produces a persistent barrage of nociceptive impulses that trigger peripheral and central sensitization phenomena, affecting the metamere innervated by the corresponding nerve root. This process produces clinical manifestations of hyperalgesia and/or allodynia in dermatomes, myotomes, and sclerotomes with a typical regional distribution known as spinal segmental sensitization (SSS). The activation of new peripheral nociceptive foci within the affected metamere can further aggravate the clinical picture. This disorder is usually classified as non-specific for being a somatosensory nervous system dysfunction without evident structural damage, which can lead to confusion since the magnitude of pain and disability reported by the patient appear to be disproportionate to the findings of auxiliary tests. In the absence of a timely diagnosis and adequate treatment, patients may resort to alternative therapies, which often do not solve the problem. The use of a standardized set of diagnostic criteria will help clinicians identify SSS and help researchers conduct studies in homogeneous populations. This review of its pathophysiology provides a foundation for rationally and systematically establishing the best treatment schemes and thus will benefit the many patients who suffer from this syndrome, which represents a challenge for","PeriodicalId":92704,"journal":{"name":"Physical medicine and rehabilitation research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67509662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Skeleton-driven dynamics modeling for computer-aided muscular rehabilitation","authors":"Jianping Cai, Feng Lin","doi":"10.15761/pmrr.1000220","DOIUrl":"https://doi.org/10.15761/pmrr.1000220","url":null,"abstract":"animating a skeletal character in computer-aided muscular rehabilitation, we innovate in both skinning and dynamic simulation. First, a new rigging scheme is proposed for transforming the bone- constrained nodes; and the motion of the unconstrained nodes can be efficiently computed by dynamic deformation simulation. Secondly, a position-based dynamics framework is employed; instead of geometrical constraints, nonlinear strain-based constraints are utilized in the tetrahedral body mesh deformation. Thirdly, in order to improve the computational performance, a unique layered constraint solving scheme is designed to solve the constraints in an ordered way; anisotropic deformations of the body mesh can be achieved by the desired stretch and shear coefficients in the different layers. Finally, we provide an interactive tool for local reference frames which control the anisotropic deformation behaviours. Real-time skeletal animation can be realized, and the model is stable even in the cases of large deformation and degeneration. The comparative advantages over the competing methods are presented and verified with experiments.","PeriodicalId":92704,"journal":{"name":"Physical medicine and rehabilitation research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67509477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sereen Jabaren, T. Jacob, Y. Grosman, Dmitry German
{"title":"Intensity and frequency of musculoskeletal pain among statin and non-statin taking patients referred to physical therapy - A cross sectional survey","authors":"Sereen Jabaren, T. Jacob, Y. Grosman, Dmitry German","doi":"10.15761/pmrr.1000214","DOIUrl":"https://doi.org/10.15761/pmrr.1000214","url":null,"abstract":"The use of statins to reduce low-density cholesterol is widespread worldwide for prevention and treatment of cardiovascular diseases and considered to be the first-line therapy for hypercholesterolemia [1-4]. About 25 million people worldwide use lipid-lowering drugs on a regular basis [1,2] and about 19% of the population of Israel [5,6]. Statins drugs (LDL-C) inhibit 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase which is responsible for the rate of cholesterol synthesis [7]. They have been shown to reduce morbidity and mortality associated with cardiovascular disease [8,9].","PeriodicalId":92704,"journal":{"name":"Physical medicine and rehabilitation research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67509414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Rust, N. Lutz, Zumbrunnen, M. Imhof, Ö. Yaldizli, Haller, Allum Jhj
{"title":"Benefits of short-term training with vibrotactile biofeedback of trunk sway on balance control in multiple sclerosis","authors":"H. Rust, N. Lutz, Zumbrunnen, M. Imhof, Ö. Yaldizli, Haller, Allum Jhj","doi":"10.15761/PMRR.1000213","DOIUrl":"https://doi.org/10.15761/PMRR.1000213","url":null,"abstract":"Background and aims: Patients with multiple sclerosis (MS) suffer from diminished balance control. We examined whether 4 sessions of training with vibrotactile biofeedback (VTfb) of trunk sway could improve their balance control and provide a carry-over effect. Methods: Baseline trunk sway was first measured for 15 MS patients. Then they received head mounted VTfb of trunk sway which was directionally active when trunk sway exceeded limits set using the baseline assessments. Stance and gait tasks were trained 2 times weekly for 2 weeks with VTfb. Assessments with VTfb were performed at the end of each week. Two weeks later balance was assessed without VTfb to determine if a carry-over effect was present. Results: Assessments with VTfb showed a significant decrease in trunk sway after 1 and 2 weeks of VTfb training (p<0.02). Carry-over improvements were also present (p<0.02). The greatest effects were found for tests of standing eyes closed stance on foam which resulted in a 59% decreased pitch sway angle (p=0.002) with VTfb and a 51% reduction (p=0.03) carry-over effect. Conclusions: This study indicates that balance control in MS patients improves rapidly after one week of training with VTfb and more slowly subsequently. The carry-over effect lasted at least 2 weeks. Future studies should determine, with more weeks of VTfb training, the time course of the slower balance and carry-over improvements following the first rapid improvement in balance control. We conclude that training with VTfb of trunk sway significantly improves balance control in MS patients, and could possibly reduce falls.","PeriodicalId":92704,"journal":{"name":"Physical medicine and rehabilitation research","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67509431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alison Hock, Justis Beley, M. Bennett, Nick Buitelaar, Amy Connell, K. Rickaby, L. Coman, S. Wojkowski
{"title":"Unmet needs for community-based physiotherapy services for adults in Canada and the United States: a scoping review protocol","authors":"Alison Hock, Justis Beley, M. Bennett, Nick Buitelaar, Amy Connell, K. Rickaby, L. Coman, S. Wojkowski","doi":"10.15761/PMRR.1000210","DOIUrl":"https://doi.org/10.15761/PMRR.1000210","url":null,"abstract":"Healthcare is available through various systems and access points. However, differences in economic status can create disparities in access to healthcare services [1]. It is not the responsibility of a sole proprietor, but rather all countries, to raise more funds, or diversify funding sources, to relieve the burden of unmet needs in healthcare [2]. However, it is the government’s duty to ensure that all public and private healthcare providers operate efficiently to fulfil patient needs [2]. Schneider et al. compared 11 high-income countries on 72 indicators of performance in five domains of healthcare: process, access, administrative efficiency, equity, and outcomes [3]. The United States (US) was ranked last, receiving particularly poor scores in access and affordability. Canada’s results were also substandard, ranking ninth overall, with its worst score in the access domain [3]. Furthermore, the US and Canada were identified as having large disparities in access between lowand high-incomes, particularly due to financial barriers [3]. In this context, patients may choose to forgo treatments or tests, due to associated costs [3].","PeriodicalId":92704,"journal":{"name":"Physical medicine and rehabilitation research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67508057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of stubbies in initial phase of rehabilitation for a woman with bilateral transfemoral amputation - a case study","authors":"T. Behera, S. Jayavant, A. Biswas","doi":"10.35248/2329-9096.20.8.579","DOIUrl":"https://doi.org/10.35248/2329-9096.20.8.579","url":null,"abstract":"Background: Individuals with a Transfemoral Amputation (TFA) may encounter impediments in day to day life because of decreased mobility. The utilization of “Stubby” prostheses in bilateral transfemoral amputees has been pushed by several authors. The significant focal points of these prostheses are that they 1) Lower the Centre of Gravity, decreasing the rate and reality of falls and 2) eliminate prosthetic knee joint, providing better control and possible reducing the cardiovascular stress of ambulation 3) Cosmesis has been the significant hindrance. Case description and method: The stubby prosthesis was designed on basis of patient’s condition and complaint. Result: The prostheses provided optimal mediolateral stability, allowed easy balance, Prevented falling backward and push-off was initiated by rocker bottom. Conclusion: This Prosthesis is an economic and design with proper biomechanical implications.","PeriodicalId":92704,"journal":{"name":"Physical medicine and rehabilitation research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70012937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Organizational Justice, Job Stress, and Work-family Conflict: Their Interrelationships in Universities' Personnel","authors":"Sorush Niknamian","doi":"10.20944/PREPRINTS201904.0099.V1","DOIUrl":"https://doi.org/10.20944/PREPRINTS201904.0099.V1","url":null,"abstract":"Presence of justice in an organization plays a crucial role on employees' well-being and remarkable success of the organization itself. This fair environment may be an important factor in lower levels of stress, which is associated with balancing demands between work and family domains among employees at university. The main purpose of this study is to investigate the relationship between distributive, procedural, and interactional dimensions of organizational justice and job stress, between work-family conflict and job stress, and whether the perception of organizational justice elements do influence work-family conflict. In sum, drawing upon 146 non-academic employees at 5 state universities in Iran, our result indicated that interactional justice had the strongest negative relationship with stress at work and work-family conflict. Moreover, the reciprocal correlation was found between job stress and work-family conflict. Hence, in order to decrease level of stress and to better manage the work and family lives, organizations need to promote justice in workplace.","PeriodicalId":92704,"journal":{"name":"Physical medicine and rehabilitation research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47934253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rehabilitation after fast-track knee arthroplasty: A scoping review on evidence-based challenges","authors":"F. Pennestrì, Negrini Francesco, Banfi Giuseppe","doi":"10.15761/PMRR.1000201","DOIUrl":"https://doi.org/10.15761/PMRR.1000201","url":null,"abstract":"The individual and social burden caused by knee osteoarthritis calls for clinical and logistical innovations to improve the effectiveness and efficiency of Total Knee Arthroplasty (TKA). Fast-track surgery is a multidisciplinary perioperative approach aimed at reducing surgical stress and facilitating postoperative recovery, resulting in decreased convalescence, better patient satisfaction, and reduced hospital costs [12]. Indeed, accelerated recovery was attributed to better coordination and collaboration between orthopaedic surgeons, physiatrists, physical therapists and patients [3].","PeriodicalId":92704,"journal":{"name":"Physical medicine and rehabilitation research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67506590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}