Journal of endocrinology and thyroid research最新文献

{"title":"Relation of Urobilinogen Presence Resence in the Selection of Food (Salty or Sweet)?","authors":"M. Qadir, F. Hameed","doi":"10.30564/jer.v1i2.1315","DOIUrl":"https://doi.org/10.30564/jer.v1i2.1315","url":null,"abstract":"The total amount of 100 subjects were contributed in this review and all were the students who are studying in Bahauddin Zakariya University Multan, Pakistan. The bilirubin is metabolized in the gut which produced a colorless pigment known as urobilinogen. It is by-product of bilirubin which is used to break down the red blood cells in hemolysis. Salty food contains usually more minerals and vitamins while sweet food is enriched with carbohydrates, water and many other fats soluble substances. Every person has a unique taste according to their taste buds. A questionnaire based was made to relate the urobilinogen with the food (salty or sweet). Urinalysis is a method which is used to measure the urobilinogen in urine. It was concluded that there is a scientific relation between the presence of urobilinogen in urine with eating of salty or sugary food. Table no. 1 represents that urobilinogen play important role in the choice of eating either salty food more or sweet.","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78895211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel StAR Gene Mutation Identified in a Moroccan Patient with Lipoid Congenital Adrenal Hyperplasia","authors":"Hanane Zaddouq, K. Belhassan, I. Haddiya, A. Gaouzi","doi":"10.30564/jer.v1i2.1149","DOIUrl":"https://doi.org/10.30564/jer.v1i2.1149","url":null,"abstract":"Congenital Adrenal Hyperplasia (CAH) is an autosomal recessive condition  that results from the deficiency of one of the steroidogenesis enzymes responsible for cortisol biosynthesis. In the majority of cases, CAH is caused by   21-hydroxylase deficiency. More rarely, the deficiency concerns  11b-hydroxylase, 3b-hydroxysteroid dehydrogenase, 17hydroxylase, or exceptionally StAR and P450 oxydoreductase. Here, we report the case of a 3 year and 4 months old male child,  born from a consanguineous marriage who presented at 15 months old with the salt-loss syndrome. Physical examination found generalized melanoderma, micropenis and bilateral cryptorchidism. Biological assessment at the time of diagnosis revealed hyponatremia, hyperkalemia, functional renal failure, hypoglycemia, low blood cortisol level, and high blood level of ACTH,  suggesting primary adrenal insufficiency. The patient presented  also with the abnormality of sexual differentiation with a 46 XY karyotype, testosteronemia level was low at the baseline and after HCG stimulation, pelvic ultrasound and MRI showed bilateral testicular atrophy in the inguinal position. The genetic study revealed a likely pathogenic homozygous variant in the StAR (steroidogenic acute regulatory) gene. Therapeutically, our patient was hydrated by saline solution and treated with hydrocortisone and fludrocortisone, then benefited from a surgical testicular correction marked by a favorable evolution. Although mutations in StAR gene are rare, they can be responsible for the defect in the early stage of steroidogenesis and therefore cause a deficiency in adrenal and sexual hormones biosynthesis.","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76638520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sodium-Glucose Co-Transporter 2 Inhibitors for Prevention and Treatment of Heart Failure","authors":"N. Mikhail","doi":"10.19080/jetr.2019.05.555656","DOIUrl":"https://doi.org/10.19080/jetr.2019.05.555656","url":null,"abstract":"","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49352187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Psycho-Neuro-Endocrino-Immunology (Pnei) of the Cardiovascular System","authors":"F. Pelizzoni","doi":"10.19080/jetr.2019.05.555655","DOIUrl":"https://doi.org/10.19080/jetr.2019.05.555655","url":null,"abstract":"The immune system has appeared to regulate not only the immune response, but all biological functions, including the nervous, the endocrine and the cardiovascular systems. At the other side, the immune system is under a physiological psycho neuroendocrine regulation, mainly modulated by the pineal gland and the opioid system, respectively in a stimulatory or in a suppressive way by influencing the cytokine network. The different cytokines exert different immunobiological effects on the immune cells, mainly by influencing the interactions between lymphocyte and monocyte-macrophage systems. The functionless of the whole immune system may be synthesized by the lymphocyte-to-monocyte ratio (LMR), and the evidence of an abnormally low LMR has been proven to be associated with a poor prognosis in all systemic severe inflammation-related human diseases, including cancer, autoimmune diseases and the cardiovascular disorders. Within the cytokine group, lL-17, IL-6, IL-1 beta, TNF alpha, and IL-18 represent the most important inflammatory cytokines involved in systemic human pathologies, whereas the most effective anti-inflammatory cytokines are consisting of TGF-beta and IL-10. The evidence of abnormally high levels of inflammatory cytokines may predict a worse prognosis in all systemic diseases. Within the neuroendocrine system, the secretion of melatonin (MLT), which represents the most investigated immunomodulating pineal hormone, has appeared to increase LMR by stimulating lymphocyte proliferation and inhibiting the monocyte macrophage system. Moreover, it has been shown that a decrease in MLT secretion may be associated with a poor prognosis in cardiovascular diseases. Therefore, MLT administration could be effective in reducing myocardial infarction and stroke-induced tissue damage. Further studies, by concomitantly evaluating MLT secretion in relation to changes in LMR values, as well as in IL-17 and IL-18 blood levels, will be required to establish whether the immune changes occurring during cardiovascular and systemic inflammatory diseases may depend at least in part on a diminished pineal function.","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46748566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Successful Case Study on Ayurvedic Management of Hypothyrodism","authors":"Dnyaneshwar Kantaram Jadhav","doi":"10.19080/jetr.2019.05.555654","DOIUrl":"https://doi.org/10.19080/jetr.2019.05.555654","url":null,"abstract":"We all know that Ayurveda is life science, which has solutions for all heath related issues. Hypothyroidism is one of the most common endocrine disorder seen in daily opd. As per charak we can categorize Hypothyroidism in Anukta vhadhies . Vata and kapha are two main doshas involved in this vhadhies. Present case is one of my successful case of hypothyroidism. 32 year’s male patient suffering from weakness, dry skin, poor memory, hair loss, constipation, acidity, breathlessness since last 8 years, and from last one month all symptoms increases rapidly. Patient having history of diabetes and thyroid and under allopathic treatment since last 8 years. After 1.5 months Ayurvedic treatment patient got relief in most of symptoms of disease and TSH level reduced from 18.71 to 3.05.","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47070902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ovarian Morphology by Ultrasound Imaging in Adolescents with PCOS and Age-Matched Controls","authors":"Asanidze Elene","doi":"10.19080/jetr.2019.05.555653","DOIUrl":"https://doi.org/10.19080/jetr.2019.05.555653","url":null,"abstract":"We determined the efficiency of ultrasound imaging (US) usage in adolescents for the diagnosis of PCOS, by comparing ovarian morphology in adolescent girls with and without polycystic ovary syndrome (PCOS) using a US study that involved 160 adolescents (13 -19 years): 85 with PCOS (study group) and 75 healthy adolescents (control group). Results indicate that ovary volume and mean follicle size in PCOS adolescents and controls did not differ significantly, but AFC in PCOS patients were significantly higher than in controls p<0.001.","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44364563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefits of Melatonin in Health Through the Regulation of Biological Rhythms: An Update on its Therapeutic Use","authors":"Aline Silva de Aguiar","doi":"10.19080/jetr.2019.05.555651","DOIUrl":"https://doi.org/10.19080/jetr.2019.05.555651","url":null,"abstract":"Melatonin is one of the major hormones related to circadian cycle regulation in the human body. More and more studies are showing benefits of its therapeutic use, both in supplemental form and with food sources. Benefits include improvements in metabolism, antioxidant profile and sleep quality. However, there is still a need to establish the best dietary sources for this nutrient and safe supplementation doses for specific population groups.","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49134558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk-Factor Analysis for Feline Hyperthyroidism in the Metropolitan Area of Porto Alegre: A Pilot Case-Control Study","authors":"C. Barbieri","doi":"10.19080/jetr.2019.04.555650","DOIUrl":"https://doi.org/10.19080/jetr.2019.04.555650","url":null,"abstract":"","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49046436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extensive Polyostotic Fibrous Dysplasia Associated with DTC Evaluated With 99mtc- MDP and 131I Whole Body Scan","authors":"Lin Li","doi":"10.19080/jetr.2019.04.555649","DOIUrl":"https://doi.org/10.19080/jetr.2019.04.555649","url":null,"abstract":"","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46453598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Nerve Fiber Layer, Macular & Choroidal Thickness in Cases with Hypothyroidism & Hyperthyroidism","authors":"Marwa Sayed Abdel Latif Eissa","doi":"10.19080/jetr.2019.04.555648","DOIUrl":"https://doi.org/10.19080/jetr.2019.04.555648","url":null,"abstract":"","PeriodicalId":92667,"journal":{"name":"Journal of endocrinology and thyroid research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44571884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}