British journal of hospital medicine最新文献

{"title":"Incorporating Menstruation Across Hospital Specialties to Improve Care for Women of Reproductive Age.","authors":"Marianne Watters, Anna Glasier, Jacqueline Ann Maybin","doi":"10.12968/hmed.2024.0944","DOIUrl":"https://doi.org/10.12968/hmed.2024.0944","url":null,"abstract":"<p><p>Women and those who menstruate currently experience health inequalities. Menstruation should be viewed as a vital sign in women of reproductive age and can be useful when assessing overall health. Menstrual parameters should be part of the routine systemic enquiry when taking a history from those who menstruate, regardless of the clinical speciality to which they present. This will facilitate prompt detection and appropriate treatment of those with iron deficiency, a common finding in those who experience heavy or prolonged menstrual bleeding. A standardised approach should be used during history taking and documentation to improve scientific progress, aid communication across specialties and to provide the holistic clinical care that women require and deserve.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 3","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changing the Narrative: Confronting Diabetes-Related Stigma in Healthcare.","authors":"Mayank Patel","doi":"10.12968/hmed.2024.0923","DOIUrl":"https://doi.org/10.12968/hmed.2024.0923","url":null,"abstract":"<p><p>Stigma refers to negative attitudes and beliefs that are directed at individuals based on perceived differences, such as living with diabetes. Stigma is commonly experienced by those with diabetes. Stigmatization often originates from healthcare professionals (HCPs) who may be unaware of the consequence of their judgemental attitudes on patients and on how personally challenging living with diabetes can be. A lack of empathy from HCPs can risk individuals choosing not to manage their diabetes as advised or even seek support. Harmful comments may also evoke feelings of guilt or shame in individuals, which can further affect their mental wellbeing and ability to self-care appropriately. Wider HCP understanding and appreciation of the impact of stigma in diabetes care could do much to help individuals with diabetes feel supported and understood and not judged. More constructive, person-centred dialogue offered by HCPs, such as avoiding using the threat of developing diabetes complications to drive individual behaviour change has the potential to contribute to better outcomes in diabetes and improve the confidence of individuals living with diabetes in their healthcare teams.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 3","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers to Clinical Academic Surgical Training and Career Development in the United Kingdom: A Review from the National Institute for Health and Care Research (NIHR) Advanced Surgical Technology Incubator (ASTI) Group.","authors":"Vassili Crispi, William Bolton, Manish Chand, Stefano Giuliani, Victoria Wykes, Ryan K Mathew","doi":"10.12968/hmed.2024.0419","DOIUrl":"https://doi.org/10.12968/hmed.2024.0419","url":null,"abstract":"<p><p>Clinical academics play a vital role in advancing medical research, knowledge and treatments within the National Health System (NHS), but this career's sustainability is at risk due to barriers to accessing and pursuing research opportunities throughout a surgeon's training and career. Despite the diversification of surgical training with integrated opportunities, challenges such as limited training opportunities, lack of protected research time, and financial constraints persist. This paper from the National Institute for Health and Care Research (NIHR) Advanced Surgical Technology Incubator (ASTI) group highlights these issues, addressing the competitiveness of academic pathways, workload balance, mentorship importance, and the need for standardised assessments. It highlights the need for greater accountability from healthcare employers and academic institutions. Additionally, the paper focuses on increasing diversity and inclusion in clinical academia, addressing systemic discrimination, and changing the NHS culture. This paper calls for collective efforts from the medical profession, government, and institutions to address these issues.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 3","pages":"1-12"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Update on Vasculitis for the General Physician.","authors":"Julia Day, Helena Crawshaw, Kian Wah Lim, John D Pauling, Harsha Gunawardena","doi":"10.12968/hmed.2024.0435","DOIUrl":"https://doi.org/10.12968/hmed.2024.0435","url":null,"abstract":"<p><p>The term vasculitis is used to describe a heterogenous group of rare disease characterised by immune-mediated damage to the blood vessels resulting in downstream ischaemia, tissue injury and end-organ damage. The classification of vasculitis is based upon the size of the vessels typically affected, which results in the broad range of clinical features associated with the different forms of vasculitis. Advances in treatment of vasculitis from the emergence of corticosteroids to the modern application of targeted immunomodulatory treatments have resulted in lower mortality associated with vasculitis but it is still associated with high healthcare resources and disease-related morbidity. Vasculitis is typically managed by rheumatologists working alongside a broad multi-disciplinary team with input from a range of medical and surgical specialties, reflecting its truly multisystem nature. Vasculitis will often present on general medical wards, with diagnosis sometimes delayed as more common infective and malignant diseases are excluded. General physicians require an understanding of the clinical features of vasculitis and have knowledge of the relevant practical approaches to investigation and management of suspected vasculitis. The present review shall provide an over-arching summary of the different forms of vasculitis and a practical approach to investigation and management aimed at the general physician.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 3","pages":"1-21"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Asthma Education Program on Disease Management in Children with Asthma: A Retrospective Analysis.","authors":"Yansong Lv, Ju Xue, Zhu Meng, Qing Zhang","doi":"10.12968/hmed.2024.0764","DOIUrl":"https://doi.org/10.12968/hmed.2024.0764","url":null,"abstract":"<p><p><b>Aims/Background</b> As a common chronic respiratory disease, asthma may lead to airway inflammation and accelerated, progressive loss of lung function, if not well controlled, posing risks to patients' life and health. This study evaluates the impact of asthma education program on enhancing asthma control, quality of life, and pulmonary function in children, addressing gaps in existing management approaches. <b>Methods</b> In this retrospective study, 60 patients who had undergone routine nursing mode at Beijing Shijitan Hospital affiliated to Capital Medical University from May 2022 to May 2023 were enrolled for the reference group; after excluding 3 patients, this study finally included 57 patients. Separately, 55 patients who had attended the child-oriented asthma education program on the basis of routine nursing care at the same hospital from May 2023 to May 2024 were enrolled for the observation group; after excluding 2 patients, this study eventually included 53 patients. The Childhood Asthma Control Test (C-ACT) score, the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) score, pulmonary function index levels measured in terms of percentage of predicted forced vital capacity (FVC%), peak expiratory flow (PEF), forced vital capacity in one second/forced vital capacity (FEV1/FVC), and the disappearance time of clinical symptoms (dyspnea, chest tightness, cough, wheezing) were compared between the two groups. <b>Results</b> Before the management, there were no differences in the C-ACT and PAQLQ scores between the two groups (<i>p</i> > 0.05). After management, the C-ACT and PAQLQ scores of the observation group were significantly higher than those of the reference group (<i>p</i> < 0.001). There were no differences in FVC%, PEF, and FEV1/FVC between the two groups before management (<i>p</i> > 0.05). After management, the FVC%, PEF, and FEV1/FVC levels of the observation group were higher than those of the reference group (<i>p</i> < 0.001). The disappearance time of clinical symptoms such as dyspnea, chest tightness, cough and lung wheezing in the observation group was shorter than that in the reference group (<i>p</i> < 0.001). <b>Conclusion</b> The child-oriented asthma education program is beneficial to the disease management in children with asthma, improving asthma control, quality of life, lung function indexes, and shortening the time of symptom disappearance.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 3","pages":"1-12"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Academic Medicine is at Risk.","authors":"Peter Mathieson","doi":"10.12968/hmed.2024.0782","DOIUrl":"https://doi.org/10.12968/hmed.2024.0782","url":null,"abstract":"<p><p>A \"perfect storm\" of National Health Service (NHS) service demands, funding challenges, career-path rigidities, work/life balance considerations and cost of living pressures are combining to make academic clinicians an endangered species. This article mainly focuses on medical professionals but similar considerations apply to all healthcare professions. Research, teaching and training tend to be de-prioritised when clinical service delivery is under extreme pressure. In the context of the acute phases of the Covid pandemic, this was perhaps justifiable but there is a risk that it has become the new normal. As well as reliable evidence of patient, carer and societal benefits, health research underpins economic prosperity. A recent report from the Academy of Medical Sciences, co-chaired by the author and Dame Julia Goodfellow, analysed the issues and proposed some solutions. The UK's pre-eminent position in health research and innovation is under threat. For the benefit of future generations, it is imperative that actions are taken sooner rather than later.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 3","pages":"1-5"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of <i>Helicobacter pylori</i> Antibiotic Resistance on Treatment Outcomes in Gastrointestinal Lymphomas: A Meta-Analysis.","authors":"Peijun Wang, Nan Wang, Jie Han, Huan Ma","doi":"10.12968/hmed.2024.0103","DOIUrl":"https://doi.org/10.12968/hmed.2024.0103","url":null,"abstract":"<p><p><b>Aims/Background</b> With the increasing prevalence of antibiotic-resistant strains of <i>Helicobacter pylori</i> (<i>H. pylori</i>), especially in the context of its association with gastrointestinal (GI) lymphomas, understanding the current patterns of resistance and their implications for treatment strategies is crucial. Our study aims to investigate the antibiotic resistance patterns of <i>H. pylori</i> in patients with GI lymphoma. <b>Methods</b> A comprehensive literature search was conducted using major electronic databases up to August 2023. The primary focus was on the antibiotic resistance patterns of <i>H. pylori</i> in GI lymphoma. The data included study characteristics, patient demographics, details of <i>H. pylori</i> antibiotic resistance, and outcomes such as all-cause mortality (AM), tumor progression rate (TPR), clinical cure rate (CCR), and long-term recurrence rate (LRR) following initial cure in patients with GI lymphoma. <b>Results</b> From 2325 identified articles, 9 were included, representing 934 patients with GI lymphoma. Significant differences in AM were observed in patients who were resistant to clarithromycin (standard mean difference, SMD: 2.27, 95% confidence intervals, CIs: 0.63 to 3.91, <i>p</i> = 0.007) and there were no differences in AM between amoxicillin-resistant patients and controls (SMD: 1.35, 95% CIs: -0.54 to 3.25, <i>p</i> = 0.16). Patients who were resistant to both clarithromycin and amoxicillin showed a pronounced difference in AM (SMD: 5.13, 95% CIs: 1.78 to 8.48, <i>p</i> = 0.003). Clarithromycin resistance significantly affected CCR after <i>H. pylori</i> eradication therapy (SMD: -4.12, 95% CIs: -5.42 to -2.82, <i>p</i> < 0.00001). Elevated TPR was observed in patients who were resistant to clarithromycin (SMD: 7.09, 95% CIs: 4.57 to 9.61, <i>p</i> < 0.00001) and amoxicillin (SMD: 11.03, 95% CIs: 5.81 to 16.25, <i>p</i> < 0.0001). LRR also exhibited significant differences in patients who were resistant to clarithromycin (SMD: 9.31, 95% CIs: 6.16 to 12.47, <i>p</i> < 0.00001) and amoxicillin (SMD: 13.81, 95% CIs: 2.78 to 24.85, <i>p</i> = 0.01). <b>Conclusion</b> Increasing antibiotic resistance in <i>H. pylori</i> strains poses a significant challenge for the treatment of GI lymphomas. Tailored treatment strategies in which resistance patterns are imperative for effective management and improved patient outcomes.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 3","pages":"1-14"},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Predictive Significance of Carotid Ultrasound Parameters for Coronary Artery Disease: A 3-Year Single-Center Experience.","authors":"Qin Wang, Jingchun Li, Jing Cheng","doi":"10.12968/hmed.2024.0682","DOIUrl":"https://doi.org/10.12968/hmed.2024.0682","url":null,"abstract":"<p><p><b>Aims/Background</b> Coronary angiography is a widely used invasive approach for diagnosing coronary atherosclerotic heart disease (CHD). However, carotid ultrasound may predict CHD by assessing carotid atherosclerosis. Therefore, this study explores the predictive significance of carotid ultrasound parameters in accurately diagnosing coronary artery disease. <b>Methods</b> This retrospective analysis included 82 CHD patients who underwent carotid ultrasound scans at the Funan County Hospital of Traditional Chinese Medicine, China, between July 2021 and February 2024. Based on coronary angiography results, patients were divided into the CHD (n = 48) and non-CHD (n = 34) groups. Differences in clinical data, biochemical indicators, and carotid ultrasound parameters were evaluated between the two experimental groups. Furthermore, correlation analysis assessed the association between ultrasound parameters and CHD occurrence and severity. Additionally, multivariable logistic regression analyses were performed, followed by developing a CHD prediction nomogram model. Finally, the model's performance was evaluated through analyses of receiver operating characteristic (ROC) curves, decision curve analysis (DCA), and calibration curves. <b>Results</b> The CHD group had higher body mass index (BMI), smoking history, diabetes, total cholesterol (TC), and triglycerides (TG) levels (<i>p</i> < 0.05). Furthermore, significantly higher intima-media thickness (IMT) and plaque score and lower plaque echogenicity grey scale median (GSM) were observed in the CHD group (<i>p</i> < 0.05). Pearson correlation showed a positive correlation between Gensini score and IMT, plaque score, and a negative association with plaque echogenicity GSM (<i>p</i> < 0.05). Spearman correlation revealed positive correlations between BMI, smoking history, diabetes, TG, TC, IMT, plaque score, and CHD diagnosis, and a negative correlation with plaque echogenicity GSM (<i>p</i> < 0.05). IMT and plaque score were identified as CHD risk factors and plaque echogenicity GSM as a protective factor (<i>p</i> < 0.05). The model based on carotid ultrasound parameters demonstrated high predictive performance for CHD, with an area under the curve (AUC) of 0.866 (95% confidence interval [CI]: 0.779-0.953). DCA and calibration curves supported the model's accuracy. <b>Conclusion</b> Carotid ultrasound parameters differ significantly between CHD and non-CHD patients. The developed model using these parameters effectively predicts CHD occurrence, providing a valuable diagnostic alternative for coronary angiography.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 2","pages":"1-17"},"PeriodicalIF":1.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Subclinical Atherosclerosis in Patients with Psoriasis Using Echocardiographic Coronary Flow Reserve Parameters: A Systematic Review and Meta-Analysis.","authors":"Hritvik Jain, Muhammad Daoud Tariq, Abdul Moiz Khan, Areeba Ahsan, Eeshal Zulfiqar, Syeda Shahnoor, Jyoti Jain, Raheel Ahmed, Ramez M Odat, Agha Wali, Rozi Khan","doi":"10.12968/hmed.2024.0618","DOIUrl":"https://doi.org/10.12968/hmed.2024.0618","url":null,"abstract":"<p><p><b>Aims/Background</b> Psoriasis is a chronic inflammatory condition associated with an elevated risk of cardiovascular diseases including coronary artery disease (CAD). This study assessed coronary microvascular dysfunction (CMD) in psoriasis patients using echocardiographic coronary flow parameters, controlling for traditional cardiovascular risk factors and atherosclerosis, to fill gaps identified in previous research. <b>Methods</b> A comprehensive literature search was performed using multiple electronic databases for studies on echocardiographic coronary flow parameters in patients with psoriasis. The outcomes of interest included the coronary flow velocity reserve (CFVR), hyperemic diastolic peak flow velocity (DPFV), and baseline DPFV. Data were extracted and analyzed using RevMan 5.4 (Nordic Cochrane Center, Copenhagen, Denmark), with pooled standard mean differences (SMDs) and 95% confidence intervals (CIs) were calculated. Statistical significance was set at <i>p</i> < 0.05. <b>Results</b> Four studies involving 557 patients were included in this analysis. Pooled analysis revealed a significant reduction in CFVR in patients with psoriasis compared to controls (SMD: -0.71; 95% CI: -0.97, -0.45; <i>p</i> < 0.00001). Hyperemic DPFV was significantly reduced (SMD: -0.71; 95% CI: -1.30, -0.12; <i>p</i> = 0.02), whereas baseline DPFV showed no signficant difference (SMD: 0.20; 95% CI: -0.92, 1.32; <i>p</i> = 0.73). <b>Conclusion</b> Psoriasis was associated with reduced CFVR and hyperemic DPFV, suggesting early CMD. CFVR could aid in early CMD detection in psoriasis patients, informing cardiovascular risk management and potential anti-inflammatory treatment benefits. <b>Systematic Review Registration</b> PROSPERO: CRD42024574085.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 2","pages":"1-16"},"PeriodicalIF":1.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Prediction of Death Risk in Progressive Nasopharyngeal Carcinoma Using Radiomics Nomogram Based on Clinical Semantic Multi-Parameter Magnetic Resonance Imaging.","authors":"Yuzhen Xi, Yuanhui Ding, Yingjiao Zhang, Mengze Wang, Chunying Wu, Xuan Chen, Lei Ruan, Zhongxiang Ding, Feng Jiang, Miao Liu","doi":"10.12968/hmed.2024.0658","DOIUrl":"https://doi.org/10.12968/hmed.2024.0658","url":null,"abstract":"<p><p><b>Aims/Background</b> Patients with recurrent or/and metastatic nasopharyngeal carcinoma (NPC) have a notably low survival rate. Our primary objective in this study is to establish a comprehensive nomogram model based on clinical factors, semantic features, and multi-parameter magnetic resonance imaging (MRI) radiomic features, and to predict the risk of mortality in patients with progressive NPC following intensity-modulated radiation therapy. <b>Methods</b> A retrospective study, including 110 patients with recurrent or/and metastatic NPC who underwent treatment at the Zhejiang Cancer Hospital between June 2012 and December 2016, was conducted. Comprehensive reviews of clinical and pre-treatment MRI data were undertaken. Patients were categorized into two groups based on their mortality status within a 5 year-frame: the non-death group (54 cases) and the death group (56 cases). Radiomic features were extracted from patients' MRIs and the best feature set was selected. Each patient was assigned a radiomic score (Rad-Score). A combined model was constructed using multivariate binary logistic regression, incorporating Rad-Score, semantic features, and clinical data. Receiver operating characteristic (ROC) curves and calibration plots were generated to evaluate the predictive performance of the radiomic feature model, the clinical-semantic feature model, and the combined model for predicting death risk in patients with progressive NPC. A nomogram based on the combined model was constructed. <b>Results</b> Gender, invasion of the carotid sheath by the primary tumour, tumour volume, and progression time showed statistically significant differences between the two groups (<i>p</i> < 0.05). There were statistically significant differences between the three models in the death and non-death groups (<i>p</i> < 0.001). The area under the curve (AUC) value for the radiomic feature model was 0.861 (95% confidence interval [CI]: 0.783-0.920), while the AUC value for the clinical-semantic feature model was 0.797 (95% CI: 0.709-0.868). The combined model demonstrated the highest efficacy for predicting death risk in NPC patients, with an AUC value of 0.904 (95% CI: 0.832-0.952), accuracy of 0.818, sensitivity of 0.857, specificity of 0.870, negative predictive value of 0.778, and positive predictive value of 0.857. <b>Conclusion</b> The combined model incorporating clinical features, semantic features and multi-parameter MRI radiomic features is a highly valuable tool for predicting death risk in patients with progressive NPC, providing a quantitative approach to aiding in early clinical intervention and treatment.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 2","pages":"1-18"},"PeriodicalIF":1.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}