British journal of anaesthesia最新文献

{"title":"Individualised positive end-expiratory pressure to minimise driving pressure and postoperative pulmonary complications in minimally invasive thoracic and abdominal surgery: do highly weighted open-lung trials influence the pooled estimate? Comment on Br J Anaesth 2026; 137: 231-43","authors":"Jinyi Zhou, Wuya Xue, Zhengfei Zhao","doi":"10.1016/j.bja.2026.08.050","DOIUrl":"https://doi.org/10.1016/j.bja.2026.08.050","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"36 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149085491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The environmental footprint and ecotoxicity of sevoflurane and propofol anaesthesia: do conservative modelling assumptions overstate the ecotoxicity of propofol? Comment on Br J Anaesth 2026; 137: 89-98.","authors":"Soizic Dieulouard, Jasper Kampman, Karine Nouette-Gaulain","doi":"10.1016/j.bja.2026.07.060","DOIUrl":"https://doi.org/10.1016/j.bja.2026.07.060","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of lidocaine bolus and infusion on neuromonitoring by bispectral index (BIS®), electroencephalogram periodic and aperiodic activity, and Surgical Pleth Index® during propofol-remifentanil anaesthesia: a single-centre prospective observational study.","authors":"Federico Linassi, Michele Carron, Paolo Zanatta, Duygu Aydin, Leonardo Spano, Christian Rizzetto, Luigi Polesello, Gerhard Schneider, Vincent Bonhomme, Matthias Kreuzer","doi":"10.1016/j.bja.2026.07.058","DOIUrl":"https://doi.org/10.1016/j.bja.2026.07.058","url":null,"abstract":"<p><strong>Background: </strong>Lidocaine administration during stable propofol-remifentanil anaesthesia causes a decrease in bispectral index (BIS®), although its influence on hypnosis is debated. We evaluated dose-dependent lidocaine effects on spectral EEG features and the processed parameters BIS and 95% spectral edge frequency (SEF₉₅).</p><p><strong>Methods: </strong>We conducted an observational, prospective, single-centre study analysing intraoperative data from 20 adult female patients undergoing breast surgery. During stable propofol-remifentanil target-controlled infusion, we delivered an i.v. lidocaine bolus (1.5 mg kg^-1) over 10 min, followed by a 30 min infusion at a rate of 1.5 mg kg^-1 h^-1. We evaluated the lidocaine-induced change in EEG spectral composition, including aperiodic and periodic features, BIS, SEF₉₅, and Surgical Pleth Index® (SPI).</p><p><strong>Results: </strong>We observed an increase in delta-band EEG activity and a decrease in beta-band EEG activity 4 to 6 min after the bolus, whereas BIS and SEF₉₅ did not change significantly. The alpha peak features bandwidth and centre frequency also decreased significantly in the early period. The aperiodic slope slightly but significantly increased after the bolus and during infusion. During the infusion phase, BIS and SEF₉₅ significantly decreased after 12 to 15 min, as did SPI in the later stages of the infusion phase.</p><p><strong>Conclusions: </strong>When lidocaine is given during stable propofol-remifentanil anaesthesia, changes in spectral EEG parameters occur earlier than changes in BIS, SEF₉₅ and SPI. The observed EEG and SPI changes are consistent with a predominant antinociceptive contribution to the anaesthetic-sparing effects of lidocaine, although the physiological interpretation of the derived parameters remains an evolving area of research.</p><p><strong>Clinical trial registration: </strong>NCT06135688.</p>","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-year outcomes of high-risk noncardiac surgical patients selected for preoperative multidisciplinary team discussion: secondary analysis of a prospective multicentre observational study^✰.","authors":"Romijn M Boerlage, Jacqueline E M Vernooij, Elisha Hobrink, Paul van Beest, Silvie van de Calseijde, Tanja Holl, Liedewij M J Janssen, Liane C Klinkert, Marije Marsman, Marinus J Nouwen, Mark A Wefers Bettink, Benedikt Preckel, Barbara L van Leeuwen, Suzanne Festen, Carine J M Doggen, Nick J Koning","doi":"10.1016/j.bja.2026.07.054","DOIUrl":"https://doi.org/10.1016/j.bja.2026.07.054","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of malignant hyperthermia in the UK 1988-2025: implications for prevalence, mode of inheritance, relative risk associated with RYR1 genotypes and in vitro contracture test phenotype","authors":"Essameldeen M. Aboelsaod, Catherine Daly, Nickla Fisher, Sarah Hobson, Huw Garland, Pawan K. Gupta, Jonathan G. Bilmen, Sarah Shepherd, Rachel L. Robinson, Marie-Anne Shaw, Philip M. Hopkins","doi":"10.1016/j.bja.2026.08.048","DOIUrl":"https://doi.org/10.1016/j.bja.2026.08.048","url":null,"abstract":"We used clinical and genetic data from the UK to analyse the disparity between the incidence of malignant hyperthermia (MH) reactions and the prevalence of variants in the <ce:italic>RYR1</ce:italic> gene associated with susceptibility to MH. We examined whether these data are consistent with the clinical risk of MH being inherited as an autosomal dominant trait.","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"14 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149085490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relative efficacy of exercise prehabilitation interventions and their components: a systematic review and network meta-analysis of randomised controlled trials","authors":"Daniel I. McIsaac, Taylor C. Gillmore, Mariam Al-Bayati, Karina Branje, Emily Hladkowicz, Dianna M. Wolfe, Brian Hutton","doi":"10.1016/j.bja.2026.08.052","DOIUrl":"https://doi.org/10.1016/j.bja.2026.08.052","url":null,"abstract":"Exercise is the most common approach to prehabilitation; the optimal exercise interventions to improve postoperative outcomes are unknown.","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":"5 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149085485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative electroencephalographic burst suppression: a marker of underlying cognitive vulnerability rather than a modifiable cause of postoperative delirium. Comment on Br J Anaesth 2026; 136: 1843-54.","authors":"Gaël de Rocquigny, Cyril Touchard, Kanssaa El Ayeb, Fabrice Vallée","doi":"10.1016/j.bja.2026.07.064","DOIUrl":"https://doi.org/10.1016/j.bja.2026.07.064","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149015735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elective surgical postponements and cancellations in PACE2024: definitions, denominators, and case-mix in interpreting national service data. Comment on Br J Anaesth 2026; 136: 1925-34.","authors":"Jiao Zhang, Xiaojing Wu, Yuan Li","doi":"10.1016/j.bja.2026.07.044","DOIUrl":"https://doi.org/10.1016/j.bja.2026.07.044","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149015742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to medication intake instructions before surgery in patients taking renin-angiotensin system inhibitors: a prespecified substudy of the AIPOP trial.","authors":"Judith A R van Waes, Lynn A Miggelbrink, Kim C M van der Elst, Erin H Smeijsters, Wilton A van Klei","doi":"10.1016/j.bja.2026.07.052","DOIUrl":"https://doi.org/10.1016/j.bja.2026.07.052","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149015826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuropathic pain and chronic postsurgical pain trajectories up to 12 months after surgery: a prospective observational questionnaire study.","authors":"Julia A Fischer, Markus Huber, Debora M Hofer, Michael Harnik, Janne Gierthmühlen, Ulrike M Stamer","doi":"10.1016/j.bja.2026.07.056","DOIUrl":"https://doi.org/10.1016/j.bja.2026.07.056","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":" ","pages":""},"PeriodicalIF":10.3,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149015780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}