British journal of anaesthesia最新文献

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Tracheal intubation of neonates and infants: advocating rapid adoption of routine videolaryngoscopy in teaching operating theatres 新生儿和婴儿的气管插管:提倡在教学手术室迅速采用常规视频喉镜。
IF 9.1 1区 医学
British journal of anaesthesia Pub Date : 2024-08-29 DOI: 10.1016/j.bja.2024.06.046
{"title":"Tracheal intubation of neonates and infants: advocating rapid adoption of routine videolaryngoscopy in teaching operating theatres","authors":"","doi":"10.1016/j.bja.2024.06.046","DOIUrl":"10.1016/j.bja.2024.06.046","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142104510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perioperative intravenous lidocaine infusion for chronic pain after breast cancer surgery: a trial sequential analysis of the original meta-analysis. Comment on Br J Anaesth 2024; 132: 575–87 围术期静脉注射利多卡因治疗乳腺癌术后慢性疼痛:原始荟萃分析的试验序列分析。Br J Anaesth 2024; 132: 575-87.
IF 9.1 1区 医学
British journal of anaesthesia Pub Date : 2024-08-28 DOI: 10.1016/j.bja.2024.06.047
{"title":"Perioperative intravenous lidocaine infusion for chronic pain after breast cancer surgery: a trial sequential analysis of the original meta-analysis. Comment on Br J Anaesth 2024; 132: 575–87","authors":"","doi":"10.1016/j.bja.2024.06.047","DOIUrl":"10.1016/j.bja.2024.06.047","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142092331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New methods needed to investigate the potential adverse effects of anaesthesia on neurological development in childhood 需要新的方法来研究麻醉对儿童神经系统发育的潜在不利影响。
IF 9.1 1区 医学
British journal of anaesthesia Pub Date : 2024-08-28 DOI: 10.1016/j.bja.2024.07.019
{"title":"New methods needed to investigate the potential adverse effects of anaesthesia on neurological development in childhood","authors":"","doi":"10.1016/j.bja.2024.07.019","DOIUrl":"10.1016/j.bja.2024.07.019","url":null,"abstract":"<div><div>The issue of potentially harmful effects of neurotoxicity or anaesthesia management on children undergoing general anaesthesia is still not resolved. Studies have so far been limited by methodological problems. In a retrospective cohort study, a new noninvasive method was used to demonstrate visual processing changes in children with a single previous exposure to anaesthesia. We need new noninvasive methods that can be used before and after exposure to anaesthesia and surgery to detemine possible effects on long-term neurodevelopment.</div></div>","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142092330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive pharmacodynamic performance of the Eleveld pharmacokinetic–pharmacodynamic model for propofol: comparison of predicted and measured bispectral index 埃勒韦尔德异丙酚药代动力学-药效学模型的预测药效学性能:预测和测量的双频谱指数比较。
IF 9.1 1区 医学
British journal of anaesthesia Pub Date : 2024-08-23 DOI: 10.1016/j.bja.2024.06.041
{"title":"Predictive pharmacodynamic performance of the Eleveld pharmacokinetic–pharmacodynamic model for propofol: comparison of predicted and measured bispectral index","authors":"","doi":"10.1016/j.bja.2024.06.041","DOIUrl":"10.1016/j.bja.2024.06.041","url":null,"abstract":"<div><h3>Background</h3><p>The Eleveld pharmacokinetic–pharmacodynamic model for propofol predicts bispectral index (BIS) processed electroencephalogram values from estimated effect-site concentrations. We investigated agreement between measured and predicted BIS values during total intravenous anaesthesia (TIVA).</p></div><div><h3>Methods</h3><p>Forty participants undergoing lower limb surgery received TIVA using remifentanil target-controlled infusions and propofol by manually controlled, target-guided infusions based upon the Eleveld model and directed by two pharmacokinetic computer simulation applications: PKPD Tools and StelSim. We evaluated the predictive performance of the Eleveld model by calculating median prediction errors (BIS units) and by Bland–Altman analyses. We also performed |Bland-Altman analysis of supplementary data provided by the authors of the Eleveld model.</p></div><div><h3>Results</h3><p>Whereas median prediction errors were small (MDPE –1.9, MDAPE 10), the ranges were wide (–18.5 to 24.3 and 1.7 to 24.3). The proportion of MDAPE &gt;10 BIS units was 47.8%. Bland–Altman analysis showed a small mean bias (–0.52 BIS units) with wide limits of agreement (–27.7 to 26.2). Each participant's limits of agreement did not meet the requirements for declaring interchangeability between the two measurements. The measurement differences depended on the BIS values, as indicated by the positive slopes of the differences <em>vs</em> BIS values. Bland–Altman analysis of the Eleveld model supplementary data revealed similar results.</p></div><div><h3>Conclusion</h3><p>BIS predictions by the Eleveld model should be interpreted with caution. In spite of the acceptable MDPE and MDAPE, there are unacceptable degrees of both within-subject and between-subject variation during propofol target-controlled infusions. This limits the use of adjusting targeted concentrations to achieve desired simulated BIS values with confidence.</p></div>","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0007091224004240/pdfft?md5=1eb6ab777184fff2dcbb7020cfab1ba1&pid=1-s2.0-S0007091224004240-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphine-specific IgE testing in the diagnosis of neuromuscular blocking agent allergy: proper use and interpretation 诊断神经肌肉阻断剂过敏的吗啡特异性 IgE 检测:正确使用和解释。
IF 9.1 1区 医学
British journal of anaesthesia Pub Date : 2024-08-23 DOI: 10.1016/j.bja.2024.06.045
{"title":"Morphine-specific IgE testing in the diagnosis of neuromuscular blocking agent allergy: proper use and interpretation","authors":"","doi":"10.1016/j.bja.2024.06.045","DOIUrl":"10.1016/j.bja.2024.06.045","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The radial trinity block of the upper extremity: combined block of the radial, median and lateral cutaneous nerves of the forearm for radius fracture 上肢桡侧三位一体阻滞:前臂桡神经、正中神经和外侧皮神经联合阻滞治疗桡骨骨折。
IF 9.1 1区 医学
British journal of anaesthesia Pub Date : 2024-08-23 DOI: 10.1016/j.bja.2024.07.016
{"title":"The radial trinity block of the upper extremity: combined block of the radial, median and lateral cutaneous nerves of the forearm for radius fracture","authors":"","doi":"10.1016/j.bja.2024.07.016","DOIUrl":"10.1016/j.bja.2024.07.016","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repeated postnatal sevoflurane exposure impairs social recognition in mice by disrupting GABAergic neuronal activity and development in hippocampus 小鼠出生后反复暴露于七氟烷会破坏海马中GABA能神经元的活动和发育,从而损害小鼠的社会识别能力。
IF 9.1 1区 医学
British journal of anaesthesia Pub Date : 2024-08-13 DOI: 10.1016/j.bja.2024.05.047
{"title":"Repeated postnatal sevoflurane exposure impairs social recognition in mice by disrupting GABAergic neuronal activity and development in hippocampus","authors":"","doi":"10.1016/j.bja.2024.05.047","DOIUrl":"10.1016/j.bja.2024.05.047","url":null,"abstract":"<div><h3>Background</h3><p>Repeated exposure to sevoflurane during early developmental stages is a risk factor for social behavioural disorders, but the underlying neuropathological mechanisms remain unclear. As the hippocampal cornu ammonis area 2 subregion (CA2) is a critical centre for social cognitive functions, we hypothesised that sevoflurane exposure can lead to social behavioural disorders by disrupting neuronal activity in the CA2.</p></div><div><h3>Methods</h3><p>Neonatal mice were anaesthetised with sevoflurane 3 vol% for 2 h on postnatal day (PND) 6, 8, and 10. Bulk RNA sequencing of CA2 tissue was conducted on PND 12. Social cognitive function was assessed by behavioural experiments, and <em>in vivo</em> CA2 neuronal activity was recorded by multi-channel electrodes on PND 60–65.</p></div><div><h3>Results</h3><p>Repeated postnatal exposure to sevoflurane impaired social novelty recognition in adulthood. It also caused a decrease in the synchronisation of neuronal spiking, gamma oscillation power, and spike phase-locking between GABAergic spiking and gamma oscillations in the CA2 during social interaction. After sevoflurane exposure, we observed a reduction in the density and dendritic complexity of CA2 GABAergic neurones, and decreased expression of transcription factors critical for GABAergic neuronal development after.</p></div><div><h3>Conclusions</h3><p>Repeated postnatal exposure to sevoflurane disturbed the development of CA2 GABAergic neurones through downregulation of essential transcription factors. This resulted in impaired electrophysiological function in adult GABAergic neurones, leading to social recognition deficits. These findings reveal a potential electrophysiological mechanism underlying the long-term social recognition deficits induced by sevoflurane and highlight the crucial role of CA2 GABAergic neurones in social interactions.</p></div>","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141981769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative multidisciplinary team meetings for high-risk noncardiac surgical patients: a Dutch nationwide survey 针对高风险非心脏手术患者的术前多学科团队会议:荷兰全国性调查。
IF 9.1 1区 医学
British journal of anaesthesia Pub Date : 2024-08-09 DOI: 10.1016/j.bja.2024.06.043
{"title":"Preoperative multidisciplinary team meetings for high-risk noncardiac surgical patients: a Dutch nationwide survey","authors":"","doi":"10.1016/j.bja.2024.06.043","DOIUrl":"10.1016/j.bja.2024.06.043","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141911848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison between cold and sharp modalities for testing sensory block in neuraxial labour analgesia: a prospective observational trial 在神经轴向分娩镇痛中测试感觉阻滞的冷和尖锐模式的比较:一项前瞻性观察试验。
IF 9.1 1区 医学
British journal of anaesthesia Pub Date : 2024-08-09 DOI: 10.1016/j.bja.2024.06.044
{"title":"Comparison between cold and sharp modalities for testing sensory block in neuraxial labour analgesia: a prospective observational trial","authors":"","doi":"10.1016/j.bja.2024.06.044","DOIUrl":"10.1016/j.bja.2024.06.044","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141911847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of a prevention care bundle reduces the incidence of atrial fibrillation after cardiac surgery: a single-centre study result 实施预防性护理包可降低心脏手术后心房颤动的发生率:单中心研究结果
IF 9.1 1区 医学
British journal of anaesthesia Pub Date : 2024-08-08 DOI: 10.1016/j.bja.2024.06.015
{"title":"Implementation of a prevention care bundle reduces the incidence of atrial fibrillation after cardiac surgery: a single-centre study result","authors":"","doi":"10.1016/j.bja.2024.06.015","DOIUrl":"10.1016/j.bja.2024.06.015","url":null,"abstract":"","PeriodicalId":9250,"journal":{"name":"British journal of anaesthesia","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141952959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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