{"title":"Transient Hyperphosphatasemia: A Case Report","authors":"Krittha Jeerawongpanich","doi":"10.31524/BKKMEDJ.2021.12.001","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2021.12.001","url":null,"abstract":"T ransient hyperphosphatasemia (TH) in infancy and childhood is a condition of elevated serum alkaline phosphatase (ALP) level without evidence of bone or liver disease. The common age at presentation is younger than 5 years old. However, investigations are needed to exclude other serious conditions such as liver disease or bone disease. 1 Transient hyperphosphatasemia is not associated with any anthropometric measurement or biochemical markers of calcium and vitamin D metabolism. 2 This condition is postulated to be from the immaturity of the mechanism responsible for ALP clearance resulting in an increasing level of plasma ALP. The associations between transient hyperphosphatasemia and viral, protozoal or other infections have been reported, such as gastrointestinal disease, respiratory infections, 3 and the duration of the elevation of serum alkaline phosphatase was less than 4 months in 80% of cases. 4 This condition resolves without intervention.5 Most TH cases were found to be associated with upper airway diseases, suggesting that TH might be caused by enterovirus infection. 6 This report describes a case of TH which might be associated with viral infection, TH resolved without intervention. assessed to be normal for his age. He was admitted twice in the past year for viral gastroenteritis and his last admission was 4 months ago from upper respiratory tract infection. Physical examination revealed a thin boy with a weight of 9.4 kilograms (< P3) and 82 centimeters in height (< P3). He had no dysmorphic feature, no rachitic rosary nor swelling of wrists and knees, no bowed legs or genu varus. The rest of the physical examination was normal. Abstract We report a case of a 2-year-3-month-old boy who had poor weight gain since 1 year of age. He had a history of difficulty eating since he was 6 months old. Vaccinations were up to date and his developmental assessment was normal. Physical examination revealed no dysmorphic features. His weight was 9.4 kilograms (< P3) and he was 82 centimeters in length (< P3). He had no rachitic rosary nor swelling of wrists or knees, no bowed legs or genu varus. He was referred to Burapha University Hospital for evaluation of failure to thrive. The laboratory investigations showed serum calcium of 10.2, phosphorus 4.5, magnesium 2.3 mg/dL and alkaline phosphatase 1,603 U/L. The x-ray on both knees and wrists showed no fraying and no flaring of the metaphyses. Serum 25-OH vitamin D and parathyroid hormone levels were 27.4 ng/mL and 24.7 pg/mL, respectively. The serum alkaline phosphatase decreased to 494 U/L. After 2 weeks of follow-up it further decreased to 185 U/L in 3 months with normal levels of calcium 9.8, phosphorus 5.3 mg/dL. The diagnosis of transient hyperphosphatasemia is crucial to avoid excessive investigations.","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41485636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thosporn Ekpreechakul, Wiphasiri Saiphiroonthong, W. Chaiwong
{"title":"Letter to Editor: Quantitative Fit Test of Double Layer Surgical Masks","authors":"Thosporn Ekpreechakul, Wiphasiri Saiphiroonthong, W. Chaiwong","doi":"10.31524/BKKMEDJ.2021.15.001","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2021.15.001","url":null,"abstract":"","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":"17 1","pages":"70-70"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43916039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Bhothisuwan, Niramon Pantawanant, N. Marukatat, Pramaporn Kimhamanon
{"title":"Image Guided Core Needle Biopsy (CNB) of the Breast—Part 1: Ductal Carcinoma In Situ (DCIS) and Invasive Ductal Carcinoma (IDC)","authors":"W. Bhothisuwan, Niramon Pantawanant, N. Marukatat, Pramaporn Kimhamanon","doi":"10.31524/BKKMEDJ.2021.12.003","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2021.12.003","url":null,"abstract":"There are varied mammographic and ultrasonographic manifestations of breast carcinomas that begin in the milk ducts and are confined to the ducts and lobules or penetrated through the duct wall into the stroma. The mammographic findings include focal masses with or without spiculated hyperdense lesion, oval or lobulated shape, various patterns of microcalcifications, asymmetric density, architectural distortion, and associated features such as skin thickening and retraction, nipple retraction, and axillary lymphadenopathy. The ultrasonographic abnormalities include masses (solid or cystic) and their shapes, margins, echo patterns, posterior acoustic features, calcifications, vascularity determined by color Doppler imaging, and effects on surrounding tissue. Radiologists play no role in giving direct pathological reports. Our role is to describe the findings and give an impression of what they look like in terms of Breast Imaging Report and Data System (BIRADS). For any suspected lesion with a chance of malignancy of 2% and above (BIRADS 4 and 5), a pathological study is recommended. For any lesions seen by ultrasonography (US), a US-guided core needle biopsy (CNB) is recommended. For lesions seen only by mammography, stereotactic guidance is appropriate. The image-guided intervention provides the pathological result that is essential for the clinician to plan treatment with the patient. Part this DCIS and IDC. The interesting cases are the varieties of presentation, different patterns of imaging findings, CNB results, and finally the surgical pathological results. 32-year-old The breast was Mammography was performed, fibroglandular breast A well-defined irregular-shaped hyperdensity mass with some extratumoral extension was detected in the right breast. No abnormal microcalcifications or posterior acoustic features are detectable. A few oval-shaped hyperdensity","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46462280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Silicosis Health Literacy among Silica Exposed Workers","authors":"Arisara Chuaypeng, N. Dumavibhat, Sitthiphon Bunman, Pennapa Kaweewongprasert, Sichon Luerithiphong, Suntaree Jeejaila, Wiyachatr Monklang","doi":"10.31524/BKKMEDJ.2021.11.05","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2021.11.05","url":null,"abstract":"OBJECTIVES: This study aims to evaluate silicosis health literacy among silica exposed workers. MATERIAL AND METHODS: We developed a 10-item silicosis health literacy questionnaire in 2018. We designed the test to evaluate the health literacy of silica exposed workers. All silica exposed workers working in 9 factories in Lampang province were enrolled in the study from October 2018 - January 2019. RESULT: A total of 435 silica exposed workers from 9 factories were included in this study. The workers were aged 20 - 70 years, and the mean age was 40.11 ± 9.10 years. 54% were female, while 43.2% worked for over ten years. The silicosis health literacy level improved significantly after a 15-minute lecture in all age groups except for those in the age group range of 60-69 years. There was no statistical difference in the levels of silicosis health literacy between males and females. CONCLUSION: The study showed that silica exposed workers improved their silicosis health literacy level significantly after intervention. Silicosis health literacy may prevent workers from the risk of silicosis exposure in Thailand in the near future.","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43077593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Air Turbulence Associated with Crew Member and Passenger Injuries on Commercial Aviation","authors":"Theera Suriyawongse","doi":"10.31524/BKKMEDJ.2021.11.004","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2021.11.004","url":null,"abstract":"OBJECTIVES: The incidence of injuries caused by air turbulences on commercial aviation in Thailand does not happen very often, therefore studies on the matter are quite rare. This research study aimed to investigate the types of organ injuries sustained in passengers, caused by air turbulence injuries, with a view to recommending appropriate preventive measures. MATERIAL AND METHODS: The study is a descriptive retrospective study of demographic data from injured passengers at Samitivej Srinakarin Hospital. Data collection began from August 1 st , 2018 and collected data dated from August 2015 to January 2020. A general analysis was made on the injury, treatment and patient length of stay, and subsequently reported in percentage format. Further analysis was performed for special injury cases. RESULT: A total of 43 patients from 8 flights was included in the study. There were 45 episodes of injuries at Samitivej Srinakarin Hospital, with 78% of these being passengers, and 76% of the patients were international passengers. 64% of patients had multiple injuries in all of the episodes. Most injuries were located on the extremities (77%), with 60% of them located on the upper extremities. The second most frequent injury was head injury (47%) and most of the head injury patients were given conservative treatment by neurological sign observation in the hospital or at home. There was no complaint of abdominal injury. From 43 patients, 68% received conservative treatments, 24% underwent operations and 8% underwent general procedures. Total admission was 53% with an average length of stay (LOS) of 7.63 days. CONCLUSION: Airplane injury cases can suffer from many types of organ injury or multiple organ injuries depending upon their activities during the time the air turbulence incurred. Cabin crew may has a higher risk of injuries than passengers.","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45972658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Chaiyodsilp, Sirada Phuriwattanapong, Weerapong Chaiyaphak, Somwong Chaiyodsilp, Phasuk Pruisart
{"title":"Determination of Vitamin B12 Deficiency Status in Vegan and Non-Vegan Thais by Assessment of Homocysteine Level","authors":"S. Chaiyodsilp, Sirada Phuriwattanapong, Weerapong Chaiyaphak, Somwong Chaiyodsilp, Phasuk Pruisart","doi":"10.31524/BKKMEDJ.2021.11.003","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2021.11.003","url":null,"abstract":"OBJECTIVES: To determine and compare vitamin B12 status in different food patterns by using serum homocysteine levels in two adult groups consisting of (1) one hundred participants in non-vegan group and (2) two hundred participants in vegan group. The vegan group is further divided into two subgroups (2.1) ordinary vegan who consumes vegan diets for more than three years and less than twenty years (2.2) high risk vegan who consumes vegan diets for more than twenty years or those who are over 65 years old or those who have signs or symptoms suggesting vitamin B12 deficiency. MATERIAL AND METHODS: This study is a descriptive cross-sectional study designed to compare the status of vitamin B12 using homocysteine level in the total 300 participants in vegan and non-vegan Thais, performed in October 2018. The study used a chemiluminescent microparticle immunoassay (CMIA) using an Architec machine to determine blood homocysteine levels. Their levels of homocysteine were then compared. The data was analyzed using the unpaired t -test. RESULT: Three hundred non-vegan and vegan Thais were included in this study. One hundred and five of these were male and 195 were female. Of these, 41% had high homocysteine levels (more than 15.4 Umol/L.), 59% of them had normal homocysteine levels (less than 15.4 Umol/L). Among one hundred non-vegans Thais (gr.1), there was only one (1%) who had a high homocysteine level. Among one hundred ordinary vegans (gr.2.1), fifty-two (52%) of them had abnormally high homocysteine. Among one hundred of high-risk vegans (gr.2.2), seventy of them (70%) had high homocysteine level. The vegan group had higher blood levels of homocysteine ( p < 0.001) than the non-vegan group. CONCLUSION: Vegan Thais have higher risk of vitamin B12 deficiency as determined by their abnormally higher homocysteine blood levels than that of non-vegans ( p < 0.001). We recommend that all Thai vegans should take vitamin B12 supplements regularly to prevent vitamin B12 deficiency. The dosage recommended by the American Vegetarian Medical Association is 50-100 micrograms per day or 500-1,000 micrograms per week. Thai vegans who do not take B12 supplementation should be screened for B12 deficiency.","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45524398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Chaiwong, T. Wiriya, Supanee Sangiamsak, Somkiat Tonphu, Atitaya Sampantasit, R. Bandasak, Ritthikrai Taweecharoen, Chulathip Boonma, R. Juneja, Ittipon Metathip, E. Lorprayoon, C. Kunanusont
{"title":"Physical Activity Level and Cardiovascular Risks of Hospital Employees: A Cross-Sectional Study in a Private Hospital.","authors":"W. Chaiwong, T. Wiriya, Supanee Sangiamsak, Somkiat Tonphu, Atitaya Sampantasit, R. Bandasak, Ritthikrai Taweecharoen, Chulathip Boonma, R. Juneja, Ittipon Metathip, E. Lorprayoon, C. Kunanusont","doi":"10.31524/BKKMEDJ.2021.11.007","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2021.11.007","url":null,"abstract":"OBJECTIVES: To assess physical activity at work of hospital employees in order to identify association between physical activity at work and risks for cardiovascular diseases MATERIAL AND METHODS: From 3,383 employees of a private hospital in Thailand in 2017, 12 percent were randomly selected based on a ten percent sample size with two percent compensation to represent eight strata of job types. After screening and exclusion, 301 subjects remained in the study. Each subject was asked to fill in the International Physical Activity Questionnaire (IPAQ) and was assessed for body fat composition using an Inbody Bio-electric Impedance Analysis (BIA) R20 model at the initiation. Each subject was equipped with an activity tracker device “Feelfit” for five days during work hours to estimate Metabolic Equivalent of Task (MET) and MET minutes per person per work week. Relevant laboratory data were extracted from annual health checkup database for the assessment of cardiovascular risk factors. Statistical analysis was conducted using STATA version 15. RESULT: The majority (85.4%) of 301 subjects were female and a little more than half (53.5%) were older than 35 years. Data from Feelfit showed 257/301 (85.4%) employees had sufficient (i.e. 600 or more MET minutes per week) physical activity (PA) at work. Operational or clinical employees were 9.8 times more likely to have adequate PA (OR 9.8, 95%CI 4.3 to 22.4). Associations between adequate PA and Body Mass Index (BMI) and waist circumference were in a different direction. Subjects with high BMI (>23 Kg/sq.m.) were more likely to have adequate PA at work (OR 3.3, 95%CI 1.0, 10.5), while those with abnormal waist circumference were less likely to have adequate PA at work (OR 0.8, 95% CI 0.2, 2.5). Around one-third of our subjects had “normal BMI obesity”, i.e. 54 (34.6%) of 156 normal BMI subjects had high body fat composition. Laboratory findings were inconclusive to demonstrate association with adequate PA. CONCLUSION: Although most hospital employees had adequate physical activity at work, one-third of subjects still had high fat composition regardless of normal BMI. Back office subjects were almost ten times less likely to have sufficient PA at work, suggesting urgent interventions for them. Relationship between impulsivity and PA was inconclusive, suggesting a larger study with greater sample size.","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42339349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Situation Report: The Operation of Bangkok Hospital Rayong Under the New Wave Outbreak of COVID-19 Between 21 December 2020 and 21 January 2021","authors":"Kawalee Sadangrit, Gunnaphon Anamnart, Sujittra Potasatian, Gidakan Kaewjon","doi":"10.31524/BKKMEDJ.2021.17.001","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2021.17.001","url":null,"abstract":"T his situation report is about the operations of the medical staff working in Bangkok Hospital Rayong under the new outbreak of COVID-19, from 21 December 2020 to 21 January 2021. The objectives of the report are to report the empirical situation relating to hospital capability to manage the situation, which can be reflected from the amount of the screening cases, the diagnostic examination and the treatment of Covid-19 patients. This situation report draws a statistical summary from the data retrieved from 21 December 2020 to 21 January 2021 at Bangkok Hospital Rayong. The results presented in this report should be beneficial for relevant agencies and interested persons. The authors have included in this report the theories and relevant guidelines as categorized below: observed in the infected patients at Bangkok Hospital Rayong","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42807131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Turajane, Pamok Saengsirinavin, Chaivat Sriratanavudhi, Wanpen Lappaiwong, J. Aojanepong
{"title":"A Prospective, Randomized, Controlled Trial Comparing Clinical Outcomes of Intraarticular Platelet Plasma Concentrate and Growth Factors versus Corticosteroid Injections in the Treatment of Knee Osteoarthritis","authors":"T. Turajane, Pamok Saengsirinavin, Chaivat Sriratanavudhi, Wanpen Lappaiwong, J. Aojanepong","doi":"10.31524/BKKMEDJ.2021.11.002","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2021.11.002","url":null,"abstract":"OBJECTIVES: To compare and evaluate the efficacy of intraarticular platelet-rich growth factor (PRGF) versus intraarticular steroid injections. MATERIAL AND METHODS: A prospective, blinded, randomized controlled trial was conducted by enrolling 650 patients with knee osteoarthritis (OA) who did not respond to the combination of oral medication and physiotherapy. After computer-based randomization and exclusion, the number of patients in our study was 557. Patients were divided into 2 groups. Group 1 (310 patients) received intraarticular PRGF injection and group 2 (247 patients) received intraarticular injection of 40-mg triamcinolone solution. The post-trial follow-up period ranged from 12 to 18.5 months. The primary endpoints were the International Knee Documentation Committee (IKDC) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores and in knee OA. However, optimal preparation techniques are essential for improved clinical outcomes, and further investigation with long-term follow-up is recommended.","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46014743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CT and MR in Cardiology","authors":"Lertlak Chaothawee","doi":"10.31524/BKKMEDJ.2021.16.001","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2021.16.001","url":null,"abstract":"","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":"17 1","pages":"71-71"},"PeriodicalIF":0.0,"publicationDate":"2021-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46023892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}