The Bangkok medical journal最新文献

{"title":"Giant Cell Tumor of Tendon Sheath in Supraclavicular Region: Cytological Aspect of a Common Tumor in an Uncommon Location","authors":"S. Plumworasawat, A. Jinawath","doi":"10.31524/BKKMEDJ.2019.02.017","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2019.02.017","url":null,"abstract":"Giant cell tumor of tendon sheath (GCTTS) is a common neoplasm, frequently developed around small digital joints of hand, and less commonly in wrist, ankle, foot and knee. GCTTS of other locations are very rare. The cytological feature of GCTTS is unique, but it could mimic neoplasm, inflammation or other lesions when arising in unusual locations. We reported a case of a 26-year-old male who presented with a supraclavicular mass. Microscopic features of excised mass revealed well-demarcated oval nodule, composed of polymorphous population of multinucleated giant cells and mononuclear cells with fibrous septa, consistent with the diagnosis of GCTTS. Local recurrence is not occurring during five-year follow-up. The purposes of this report is to present the rarity of this tumor in an exceedingly rare location and to help avoid misdiagnosis with other mimics. \u0000 \u0000Keywords: giant cell tumor of tendon sheath, cytology, localized tenosynovial giant cell tumor \u0000 \u0000DOI: 10.31524/bkkmedj.2019.02.017","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49435711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of Convolutional Neural Networks and Transfer Learning for Skeletal Bone Age Assessment","authors":"Chadaporn Keatmanee, Songphon Klabwong, Kamolphong Osatavanichvong, C. Suchato","doi":"10.31524/BKKMEDJ.2019.02.001","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2019.02.001","url":null,"abstract":"OBJECTIVES: Bone age assessment is used by clinicians for estimating the maturity of a child’s skeletal system. Traditionally, physicians use template matching methods (GP and/or TW2). Time and accuracy of the evaluation rely on a physician’s experience. Therefore, this research proposes a fully automatic system for bone age assessment with cutting edge artificial Intelligence (AI) technology. \u0000 \u0000MATERIAL AND METHODS: Convolutional Neural Network (CNNs), a Deep Learning (DL) technique is applied to skeletal bone age prediction combined with transfer learning algorithm. Hence, various kinds of transfer learning algorithms (ResNet-50, Inception-V3, and VGG-16) are investigated in training in the proposed model fed by a number of x-ray images (12,000 image approximately—imbalanced data). \u0000 \u0000RESULT: VGG-16 shows significant accuracy compared to ResNet-50 and Inception-V3 (mae = 6.53, 20.52 and 43.11 months respectively) \u0000 \u0000CONCLUSION: The most effective pre-trained layer for CNNs in bone age assessment is VGG-16 according to the accuracy of its prediction. \u0000 \u0000Keywords: deep learning, convolutional neural network, bone age, growth disorder, maturity estimation, transfer learning \u0000 \u0000DOI: 10.31524/bkkmedj.2019.02.001","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45507257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Activities of Colistin with Tigecycline Combination Against Clinical Isolates of Carbapenemresistant Acinetobacter baumannii","authors":"S. Sitaruno, W. Santimaleeworagun, S. Leelasupasri","doi":"10.31524/BKKMEDJ.2019.02.005","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2019.02.005","url":null,"abstract":"OBJECTIVES: To determine in vitro antimicrobial susceptibility and synergistic activity of colistin in combination with tigecycline against clinical strains of carbapenem- resistant Acinetobacter baumannii (CRAB). \u0000 \u0000MATERIAL AND METHODS: Colistin and tigecycline minimum inhibitory concentrations (MICs) of 12-clinical CRAB isolates were determined by broth microdilution. Checkerboard testing was performed to assess the interaction of the colistin-tigecycline combination. Fractional inhibitory concentration indexes (ΣFIC) in the range of 0.5 to 1.0, > 1.0 to < 4.0 and ≥ 4.0 are considered as additive, indifferent, and antagonistic effects, respectively. \u0000 \u0000RESULTS: All CRAB isolates were susceptible to colistin. Three out of 12 CRABs were susceptible to tigecycline based on a pharmacokinetic-pharmacodynamics (PK-PD) breakpoint (MICs ≤ 0.25 μg/mL). The MIC of both antimicrobials was decreased in most of the CRAB isolates in the checkerboard synergy testing. The interaction of colistin and tigecycline combination revealed both additive and indifferent effects in five and seven of the 12-CRAB isolates, respectively. Neither synergism nor antagonism of colistin and tigecycline combination was demonstrated. \u0000 \u0000CONCLUSION: No synergistic effect between colistin and tigecycline against CRAB isolates was detected. However, the combination of these two drugs is likely to result in a decrease in the MIC of both drugs. Further studies with a larger sample to determine the in vitro synergistic activity of colistin and tigecycline combination are required. \u0000 \u0000Keywords: in vitro, synergism, tigecycline, colistin, checkerboard method \u0000 \u0000DOI: 10.31524/bkkmedj.2019.02.005","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49642786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a Cognitive Stimulation Therapy Program on Cognitive Ability of Demented Older Adults","authors":"Berliany Venny Sipollo, Pornchai Jullamate, Naiyana Piphatvanitcha, Ed Rosenberg","doi":"10.31524/BKKMEDJ.2019.02.008","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2019.02.008","url":null,"abstract":"OBJECTIVES: This quasi-experimental study aimed to examine the effect of a cognitive stimulation therapy (CST) program on the cognitive ability of demented older adults. \u0000 \u0000MATERIAL AND METHODS: Two nursing homes were randomly assigned as experimental and control groups. Simple random sampling technique was used to recruit 27 demented older adults from each nursing home. The experimental group received a CST program three times per week for 5 weeks. The control group received usual care. Data collection was performed from March to May, 2018. Instruments used were a Demographic Questionnaire, Mini Mental State Examination (Indonesian version), and the CST program adapted for the culture of East Java, Indonesia. Descriptive statistics were calculated for data analysis. \u0000 \u0000RESULTS: Findings revealed an effect of CST on cognitive ability of demented older adults. The experimental and control groups were not significantly different before the intervention (p = 0.161). After the CST program, the mean cognitive ability score in the experimental group was significantly higher than before the program (p < 0.001). After the CST program, the mean cognitive ability score in the experimental group was significantly higher than in the control group (p < 0.001). The mean cognitive ability score for the control group did not differ significantly between pre-test and post-test (p = 0.058). \u0000 \u0000CONCLUSION: CST improves cognitive ability in demented older adults. Nurses and health care teams can apply CST beneficially with older adults with dementia. Future research could replicate this study for different levels and types of dementia. \u0000 \u0000Keywords: dementia, cognitive ability, cognitive stimulation therapy, nursing home. \u0000 \u0000DOI: 10.31524/bkkmedj.2019.02.008","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45215436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraosseous Calcaneal Lipoma","authors":"Thanis Saksirinukul","doi":"10.31524/BKKMEDJ.2019.02.022","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2019.02.022","url":null,"abstract":"A 32-year-old Cambodian male presented with intermittent right ankle pain without history of trauma. Physical examination revealed normal configuration without swelling, mild tenderness at anterolateral and anterior (A). Lateral view of right ankle radiograph demonstrated a well-defined osteolytic lesion at right calcaneal neck to body, with thin D E sclerotic rim, containing focal internal dystrophic calcification, without adjacent cortical breakthrough (B). There is a diffuse fat density in the lesion on non-contrast computed tomography (CT) (C), corresponding to additional magnetic resonance imaging (MRI) findings; bright T1W signal (D) with signal drop on fat suppression sequence, and small surrounding vascularity (E). Intraosseous calcaneal lipoma was diagnosed.","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48725896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Pressure Sore Prevention Program on Knowledge and Self-Efficacy of Family Caregivers in Decreasing Pressure Sore Risk of Persons with Cerebrovascular Disease","authors":"Suthasinee Chiaprasert, Somnuk Sakunhongsophon, Sangthong Terathongkum","doi":"10.31524/BKKMEDJ.2019.02.009","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2019.02.009","url":null,"abstract":"OBJECTIVES: This quasi-experimental research design was aimed to determine effects of pressure sore (PS) prevention program on knowledge and self-efficacy of family caregivers in decreasing PS risk of persons with cerebrovascular disease (CVD). \u0000 \u0000MATERIAL AND METHODS: Study participants were family caregivers of persons with CVD and these were randomly selected and placed into two groups: an experimental group with 27 participants receiving the PS prevention program for 8 weeks and a control group with 26 participants receiving routine nursing care at home. Data were collected using demographics questionnaire, CVD knowledge, self-efficacy of PS prevention, and Braden scale for PU risk assessment. Data were analyzed using descriptive statistics, Chi-square test, paired t-test, Wilcoxon signed ranks test, ANCOVA and Mann Whitney U test. \u0000 \u0000RESULTS: After participating in the program, family caregivers in the experimental group had a significantly mean score of CVD knowledge and self-efficacy of PS program higher than before receiving the program (p < 0.001) and the control group (p < 0.001, p < 0.05, respectively). Participants in the experimental group had a significantly mean score of PS risk higher than before receiving the program (p < 0.001). However, there was no significant difference between the groups. \u0000 \u0000CONCLUSION: The PS prevention program should be applied to family caregivers in order to reduce PS risk of persons with CVD \u0000 \u0000Keywords: knowledge, self-efficacy, pressure sore (PS), cerebrovascular disease (CVD), family caregivers, bedsore, bedridden \u0000 \u0000DOI: 10.31524/bkkmedj.2019.02.009","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47352589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Anticoagulation in 2017","authors":"T. Vanassche, Frans Van De Werf Frans","doi":"10.31524/BKKMEDJ.2018.09.015","DOIUrl":"https://doi.org/10.31524/BKKMEDJ.2018.09.015","url":null,"abstract":"In this paper we describe the properties and clinical use of new anticoagulants:dabigatran (a direct thrombin inhibitor) and direct anti-Xa agents (rivaroxaban, apixaban,edoxaban ). Major studies that have been performed with these agents in comparisonwith warfarin are reported. Recommendations for use in clinical practice are provided.Information on the disappearance of the anticoagulant effect after stopping drug intakeand on the administration of agents that neutralize the effect of the new anticoagulantis provided. \u0000 \u0000Keywords : \u0000warfarin, dabigatran, anti-Xa agents, idarucizumab \u0000 \u0000Address Correspondence to author: \u0000Frans Van, MD, PhD, FESC, FACC, FAHA Department of Cardiovascular Sciences University Hospital Leuven Herestraat-49, B-3000 Leuven, Belgium email: frans.vandewerf@uzleuven.be \u0000 \u0000Received: November 10, 2018 \u0000Revision received: December 28, 2018 \u0000Accepted after revision: January 10, 2018 \u0000BKK Med J 2018;14(2): 81-94. \u0000 \u0000DOI: 10.31524/bkkmedj.2018.09.015","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42020312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptom Experiences and Management of Patients with Head and Neck Cancer Receiving Radiation Therapy: Integrated Review","authors":"Sirikorn Rojthamarat, Chomchuen Somprasert, Puangpaka Kongvattananon","doi":"10.31524/bkkmedj.2018.09.018","DOIUrl":"https://doi.org/10.31524/bkkmedj.2018.09.018","url":null,"abstract":"There is a limited number of literature reviews of the symptom experience and self-management of head and neck cancer (HNC) patients who have undergone radiation therapy, in the period before, during, and after treatment. Moreover, a qualitative approach exploring these specific experiences and their management will benefit both health care providers and researchers to understand the factual experience. Knowledge of this kind is needed to help eliminate distress from treatment-related symptom toxicities and to develop novel and adequate interventions to support these patients’ needs. A literature search was carried out in April 2017 using Cochrane, CINAHL, Ovid, Pubmed, PsycINFO, and ScienceDirect databases to review the literature on HNC patients, symptom experience and management during radiation or concurrent chemoradiotherapy. Symptoms experienced by HNC patients mainly relate to eating difficulties and uncertainty from the moment of being diagnosed with cancer until treatment completion. Symptom management is focused on self-management for out-patients by providing guidance, and disease education is delivered by knowledgeable healthcare providers with good interpersonal skills. Communication strategies with tailored information also provide vital data found in this synthesis. Early assessment and intervention with patients, and an effective family involvement, is important to facilitate access to quality oncology services. This is vital in helping overcome the uniquely complex treatment-related symptoms and to help patients and families to cope with the difficult time of getting through the treatment trajectory. Keywords : symptom experiences, symptom management, head and neck cancer patient, radiation therapy, concurrent chemoradiotherapy, qualitative research Address Correspondence to author: Sirikorn Rojthamarat, RN, PhD Candidate Faculty of Nursing, Thammasat University, Klong Luang, Rangsit, Pathumthani 12121, Thailand email: sirikorn.roj@chulabhornhospital.com Received: August 27, 2017 Revision received: November 16, 2017 Accepted after revision: May 21, 2018 BKK Med J 2018;14(2): 108-114. DOI: 10.31524/bkkmedj.2018.09.018","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46039260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demonstration Rupture of Ovarian Cyst by MagneticResonance Imaging (MRI), STIR Pulse Sequence","authors":"Romsai Lerdpienpitayaku, C. Suchato","doi":"10.31524/bkkmedj.2018.09.021","DOIUrl":"https://doi.org/10.31524/bkkmedj.2018.09.021","url":null,"abstract":"A 27-year-old unmarried woman with acute intermittent abdominal pain for 6 hours without nausea, vomiting or fever.Urination and defecation were also normal. No leucorrhea was found in this patient. Pelvic examination appeared tobe normal. Others physical examination revealed tenderness with mild guarding at right lower abdomen. Laboratoryfindings: hemoglobin 10.8 g/dL, white blood cell 11.73 103/μL , Neutrophil 80.1%, Lymphocyte 14.4%, Monocyte 3.1%,Eosinophil 1.0%, and platelet was in normal range. Provisional diagnosis was acute appendicitis versus rupture of ovarian cyst.Pelvic Ultrasonogram was chosen to be primary imaging revealing moderate amount of fluid in pelvic cavity and extended toboth lumbar gutters and the appendix was not identified. Consequently, MRI pelvis was performed instead, the findings showedrupture of right ovarian cyst (see Fig. A). Management was conservative treatment and follow up with MRI imaging untilcomplete absorption of fluid in pelvic cavity. (Fig. B-C).","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47623290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing Outcomes of Patient’s Comfort during Neoplastic Chemotherapy: An Integrative Review","authors":"Paranee Phongnopakoon, Puangpaka Kongvattananon, Chomchuen Somprasert","doi":"10.31524/bkkmedj.2018.09.019","DOIUrl":"https://doi.org/10.31524/bkkmedj.2018.09.019","url":null,"abstract":"Advanced treatment for cancer improved most survival rates. However, there are manyside effects of treatment that affect the patient’s quality of life. Nowadays managementand reduction of treatment associated with side effects are significant in maintainingpatients’ quality of life and optimizing nursing outcomes. Cancer patients who undergochemotherapy will experience discomfort. This study aimed to identify nursing outcomesrelated to comfort among cancer patients who are undergoing chemotherapy. The methodchosen was an integrative review that drew data from five main electronic databases(PUBMED, Science direct, CINAHL, MEDLINE, Complementary index and Other) andonly 44 out of 148 papers identified met the inclusion criteria. The result showed that theliterature studies divided the theme of comfort according to the symptoms that occurredfrom chemotherapy as follows: 1) Physical comfort 2) Psychospiritual comfort 3)Sociocultural comfort and 4) Environmental comfort. Conclusion: Nursing outcomesdepend on a patient’s need and include the management not only of the physical symptomsand treatment-related side effects, but also the changes in a patient’s emotional status anddaily lives. Patients were supported by other patients with similar experiences especiallyspiritual needs, and support from family and friends had a dramatic positive impact onpatients’ adherence to treatment. The study findings are that the nursing outcomes of thepatients’ comfort after receiving chemotherapy (according to the patient’s point of viewabout the meaning of comfort) should be led by the patient’s quality of life and satisfaction. \u0000 \u0000Address Correspondence to author: \u0000Paranee Phongnopakoon, RN, PhD (Student)Faculty of Nursing, Thammasat University99 Klong1, Khlong Neung,Khlong Luang, Pathumthani12121, Thailand.email: Paranee.ph@bangkokhospital.com \u0000 \u0000Received: May 20, 2018 \u0000Revision received: May 25, 2018 \u0000Accepted after revision: July 6, 2018 \u0000BKK Med J 2018;14(2): 115-120. \u0000 \u0000DOI: 10.31524/bkkmedj.2018.09.019","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42105314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}