BMC Anesthesiology最新文献

{"title":"Preoperative thoracic paravertebral block provides greater benefits for body temperature protection in patients undergoing thoracoscopic lung surgery: a retrospective cohort study.","authors":"Yue Li, Weixin Zhang, Hansheng Liang, Liang Sun, Xinyue Gao, Yi Feng","doi":"10.1186/s12871-025-03164-1","DOIUrl":"10.1186/s12871-025-03164-1","url":null,"abstract":"<p><strong>Background: </strong>Perioperative hypothermia can lead to a variety of adverse events that hinder rapid recovery after surgery in clinical settings. General anesthesia combined with paravertebral block (PVB) may add additional heat loss and thus increase the incidence of hypothermia in patients undergoing thoracoscopic lung surgery. However, gaps in the knowledge of the influence of the PVB time sequence on patients' body temperature remain. The aim of this study was to explore the potential impact of the time sequence of PVB on the risk of hypothermia.</p><p><strong>Methods: </strong>Patients aged 18-85 years who underwent thoracic PVB (TPVB) and thoracoscopic lung surgery at a tertiary hospital were retrospectively included. All the patients were divided into a pre-PVB group and a post-PVB group on the basis of the time sequence of PVB. The demographic, anesthesia-related and surgery-related data of the patients were collected. Propensity score matching was applied, and outcomes were compared between the two groups. The primary outcome was the incidence of hypothermia in the postanaesthesia care unit (PACU). The secondary outcomes included the occurrence of chill and delayed awakening, the numeric rating scale (NRS) score, extubation time and length of stay (LOS) in the PACU.</p><p><strong>Results: </strong>A total of 1001 patients were enrolled, with 746 patients in the pre-PVB group and 255 patients in the post-PVB group. After 1:1 propensity score matching, 222 patients were included in each group. The results revealed that body temperature was significantly different between the two groups (pre-PVB group, 36.1 [36.0-36.2]°C; post-PVB group, 36.0 [36.0-36.2]°C; P = 0.012), and the incidence of hypothermia was greater in the post-PVB group than that in the pre-PVB group (24.8% vs. 16.7%, P = 0.047). The NRS scores in the PACU were higher in the pre-PVB group (0 [0-1] vs. 0 [0-0], P = 0.041). There was no statistically significant difference in the other outcomes between the two groups.</p><p><strong>Conclusions: </strong>Preoperative TPVB offers more benefits for body temperature protection in patients undergoing thoracoscopic lung surgery, but it slightly offsets the analgesic efficacy in the PACU.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"295"},"PeriodicalIF":2.3,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of maternal and neonatal outcomes between general anesthesia and combined spinal-epidural anesthesia in cesarean delivery for pregnancy complicated with placenta previa.","authors":"Tianjiao Liu, Yangyang Wang, Xinyu Xiao, Zhi Chen, Xin Li, Chunmei Liu","doi":"10.1186/s12871-025-03149-0","DOIUrl":"10.1186/s12871-025-03149-0","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Placenta previa (PP) involves abnormal placental implantation in the lower uterine segment, partially or completely covering the internal cervical os, and is linked to severe maternal hemorrhage and fetal complications. The optimal anesthetic method between general anesthesia (GA) and combined spinal-epidural anesthesia (CSEA) for cesarean delivery (CD) with PP remains controversial.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We retrospectively analyzed 550 PP-complicated CD cases from the Longitudinal Placenta Previa Study (LoPPS) conducted in Southwest China between January 2018 and December 2024. Patients received either GA (n = 170) or CSEA (n = 380). Sociodemographic, obstetric, perioperative, and neonatal data were compared. Multivariate linear and logistic regression was employed to assess the association between anesthetic methods and other perioperative factors, and intraoperative blood loss, or neonatal asphyxia while adjusting for potential confounders.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Patients undergoing GA had a higher age (32.4 vs 31.5 years, p = 0.020), higher body mass index (BMI) (26.5 vs 23.5 kg/m&lt;sup&gt;2&lt;/sup&gt;, p &lt; 0.001), and greater parity (91.8% vs 78.4%, p &lt; 0.001) compared to those under CSEA. Complete PP was more common in the GA group (47.1% complete PP vs 19.0%, p &lt; 0.001). There were also more placenta accreta spectrum (PAS) (48.8% vs 15.8%, p &lt; 0.001) and hysterectomy (12.9% vs 0.3%, p &lt; 0.001) in the GA group. In accordance with the huge differences in anesthesia indications, the GA group experienced significantly greater intraoperative blood loss (1131.77 ± 77.29 mL vs. 707.50 ± 16.87 mL, p &lt; 0.001), along with correspondingly higher rates of transfusion, including red cell suspension, plasma, and autologous blood (p &lt; 0.001). The incidence of neonatal asphyxia was also significantly higher in the GA group (26.5% vs. 3.7%, p &lt; 0.001), and the rate of preterm birth was notably higher (81.8% vs. 46.3%, p &lt; 0.001). Among CSEA patients, increased blood loss was associated with placenta covering the uterine incision (HR = 58.49, p = 0.017), PAS type (HR = 29.02, p = 0.036), PP type (HR = 34.72, p = 0.048), and surgical duration (HR = 9.35, p &lt; 0.001), while aortic balloon occlusion reduced blood loss (HR = -115.08, p = 0.009). In GA patients, similar risk factors were identified: placenta covering the incision (HR = 71.88, p = 0.015), PAS type (HR = 103.01, p = 0.042), PP type (HR = 106.16, p = 0.046), and surgical duration (HR = 13.83, p &lt; 0.001). Aortic balloon occlusion remained protective in the GA group (HR = -300.01, p = 0.015), while GA (Exp(B) = 1.75, p = 0.002) and types of PAS are associated with increased risks of neonatal asphyxia.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;CSEA is a safe option for selected cases of PP-related CD, particularly in the absence of PAS or in cases with milder forms of PP. Though the GA group exhibited greater intraoperative blood loss, due to the significant difference","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"294"},"PeriodicalIF":2.3,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of dexmedetomidine and sevoflurane on optic nerve sheath diameter and postoperative nausea and vomiting in patients undergoing microvascular decompression: a retrospective cohort study.","authors":"Qi Sun, Pengfei Li, Chang Liu, Maoxiang Gan, Qingxiang Mao, Xuzhi He, Lunshan Xu, Yi Hu","doi":"10.1186/s12871-025-03147-2","DOIUrl":"10.1186/s12871-025-03147-2","url":null,"abstract":"<p><strong>Background: </strong>Observe the effects of dexmedetomidine(Dex) and sevoflurane(Sev) on the optic nerve sheath diameter(ONSD) in patients undergoing microvascular decompression (MVD). Find the most appropriate anesthetic maintenance medication scheme to reduce intracranial pressure (ICP)fluctuation and reduce the incidence of adverse reactions such as postoperative nausea and vomiting(PONV).</p><p><strong>Methods: </strong>In this retrospective cohort study, 90 patients undergoing elective MVD surgery were allocated into Groups P, D, and S. Maintenance of anaesthesia: Group P propofol(Propo) 4-12mg/(kg.h) + remifentanil 0.1-0.2ug/(kg.min); Group D Dex 0.4ug/(kg. h) + Propo 4-12mg/(kg.h) + remifentanil 0.1-0.2ug/(kg.min); Group S 1-2% Sev + Propo 4-12mg/(kg.h) + remifentanil 0.1-0.2ug/(kg.min). The changes in ultrasound-measured ONSD relative to baseline and the occurrence of PONV at different time periods under different anaesthetic maintenance regimens were compared.</p><p><strong>Results: </strong>(1) ONSD values increased significantly from T1 (10 min after tracheal intubation) to T6 (on leaving the post-anaesthesia care unit (PACU)), compared with the same group at T0 (5 min before anaesthesia). ONSD values at each time point of T1-T6, were the lowest in the Group D and the highest in the Group S.(2)In this study, the incidence of PONV within 24 h after MVD was 38.9%, with the lowest in Group D and the highest in Group S. (3) T2 (10 min after lying on side in forward neck flexion)ONSD, T6 (on leaving the PACU)ONSD, the usage of Sev and Dex were associated with PONV, whereas the usage of 0.4ug/(kg.h) Dex was a protective factor.</p><p><strong>Conclusions: </strong>Dex has a lower effect on ONSD of MVD during the perioperative phase than Sev, and it can, to a certain extent, reduce the fluctuation of ICP. Dex lowers the incidence of PONV within 24 h after MVD and acts as a protective factor for PONV.</p><p><strong>Trial registration: </strong>The protocol of this study was registered at www.chictr.org.cn (07/02/2024,ChiCTR MR-50-24-010856).</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"293"},"PeriodicalIF":2.3,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Steroid versus steroid plus ozone during posterior epiduroscopy in the treatment of lumbar herniated disc: results of a 1-year follow-up study.","authors":"Derya Bayram, Dostali Aliyev, İbrahim Aşık","doi":"10.1186/s12871-025-03160-5","DOIUrl":"10.1186/s12871-025-03160-5","url":null,"abstract":"","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"292"},"PeriodicalIF":2.3,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A complication of double-lumen endotracheal tubes resulting in delayed laryngeal injury and dyspnea: a case report and literature analysis.","authors":"Qinye Shi, Yunxia Fang, Jianhong Xu","doi":"10.1186/s12871-025-03161-4","DOIUrl":"10.1186/s12871-025-03161-4","url":null,"abstract":"<p><strong>Background: </strong>Double-lumen endotracheal tubes(DLTs) is often used in lung surgery and is more likely to cause throat injury than single-lumen endotracheal tubes. However, it is rare to have an occult giant laryngeal cyst and upper airway obstruction after DLTs, causing severe complications such as dyspnea. This serious complication endangers the patient's life and safety.</p><p><strong>Case presentation: </strong>A 55-year-old woman underwent surgical resection of a lung tumor under DLTs. Approximately 3 months after surgery, she went to the hospital for treatment due to hoarseness and dyspnea after a change in body position. Laryngoscopy revealed that the upper airway was obstructed due to a large cyst in the throat, which required surgical resection. Although the crisis was resolved by surgical resection, this serious complication of endotracheal intubation, which could have endangered the patient's life, was indeed worrisome.</p><p><strong>Conclusions: </strong>The DLTs is thick, and the positioning of the intubation technology is high, which increases the likelihood of a throat injury. Thus, it is necessary to actively prevent its occurrence during operation. Hoarseness after operation needs early examination to detect and treat the injury early and avoid such serious complications.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"291"},"PeriodicalIF":2.3,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of liposomal bupivacaine for sciatic nerve block on opioid use in patients undergoing maxillofacial reconstruction with free fibular flap: a randomized, controlled trial.","authors":"Hai-Yin Wu, Xiao-Dong Wang, Guo-Li Xiong, Xu-Dong Yang, Li-Kuan Wang","doi":"10.1186/s12871-025-03151-6","DOIUrl":"10.1186/s12871-025-03151-6","url":null,"abstract":"","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"290"},"PeriodicalIF":2.3,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An emergency surgical airway establishment following rapid sequence induction: a rare case of laryngeal stenosis associated with tuberculosis.","authors":"Ruofan Wang, Yi He, Xiaoqiang Li, Yunxia Zuo","doi":"10.1186/s12871-025-03163-2","DOIUrl":"10.1186/s12871-025-03163-2","url":null,"abstract":"<p><strong>Background: </strong>Rapid sequence induction (RSI) is the standard airway management technique for patients requiring emergency surgery with a full stomach or intestinal obstruction, aiming to reduce aspiration risk. RSI may fail if an unexpected difficulty intubation occurred and then a mask ventilation had to be applied. The worst scenario is that mask ventilation also failed, severe hypoxia developed followed by cardiac arrest.</p><p><strong>Case presentation: </strong>A 14-year-old child with a history of pulmonary tuberculosis diagnosed with intestinal obstruction scheduled for emergency surgery. Due to high risk of aspiration, rapid sequence induction was applied. Although the preoperative airway assessment was normal, unexpectedly difficult airway was encountered. There was a failure of vocal cord exposure under video laryngoscope. A crisis happened when mask ventilation failed. Facing the disaster of \"cannot intubate, cannot ventilate\" and following severe hypoxia and cardiac arrest, the anesthesiologist established a surgical airway which successfully resuscitated the patient. A rare disease of laryngeal tuberculosis might be the underlying cause.</p><p><strong>Conclusions: </strong>Patients with a history of pulmonary tuberculosis should be carefully evaluated for the presence of laryngeal tuberculosis, with laryngeal imaging as an optional diagnostic component. When encountering unexpected difficult airways during rapid sequence intubation leading to hypoxic cardiac arrest, immediate surgical airway intervention is critical for patient survival.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"288"},"PeriodicalIF":2.3,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12142976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical value of preoperative oral carbohydrate loading in patients with diabetes: a cross-sectional study.","authors":"Shun Wang, Jie Zhang, Qiaoli Liu, Liqin Deng","doi":"10.1186/s12871-025-03165-0","DOIUrl":"10.1186/s12871-025-03165-0","url":null,"abstract":"","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"289"},"PeriodicalIF":2.3,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12142891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global prevalence of postoperative hypoxemia among adult and pediatric surgical patients: a systematic review and meta-analysis.","authors":"Yosef Belay Bizuneh, Mulualem Endeshaw Zeleke, Ashebir Mamay Gebru, Destaw Fetene Teshome, Fantahun Ayenew Mekonnen, Dessie Abebaw Angaw, Amare Belete Getahun","doi":"10.1186/s12871-025-03146-3","DOIUrl":"10.1186/s12871-025-03146-3","url":null,"abstract":"<p><strong>Background: </strong>Postoperative hypoxemia refers to a condition where oxygen levels in the tissues or blood drop to insufficient levels following surgery. The aim of this review is to determine the global prevalence of postoperative hypoxemia among adult and pediatric surgical patients through a systematic review and meta-analysis.</p><p><strong>Methods: </strong>We performed a comprehensive search across multiple databases, including Pubmed, Embase and Scopus. Additionally, search engines such as Google Scholar and Google. The searching mechanism was using medical subject heading terms combining by Boolean operators. The process adhered to the PRISMA guidelines, ensuring a robust method for the review. The review was registered at PROSPERO with registration number CRD42024534623. Risk of bias or quality assessment was done using a standardized critical appraisal instrument. Publication bias was assessed using a funnel plot and Egger's regression test. Pooled prevalence was estimated using random-effects. Subgroup analyses were conducted based on different factors. Additionally, to identify a single study effect sensitivity analysis was conducted.</p><p><strong>Result: </strong>A total of 20 primary studies with 28,948 participants were included. The pooled prevalence of postoperative hypoxemia was 20.62% (95% CI: 17.02-24.22%). Publication bias was detected, with Egger's regression test (p < 0.0001) indicating small-study effects. After imputing three studies, the pooled prevalence decreased from 20.62% (95% CI: 17.02-24.22%) to 16.76% (95% CI: 13.36-20.15%). Subgroup analysis showed the highest prevalence in Africa at 33.81% (95% CI: 25.51-42.1%) and in low-income countries at 33.81% (95% CI: 25.51-42.1%). Among emergency surgical patients, they had the higher prevalence, 21.38% (95% CI: 11.60-31.15%).</p><p><strong>Conclusion: </strong>This meta-analysis showed a pooled prevalence of postoperative hypoxemia was 20.62%, which may be over reported due to publication bias. After data imputation, the revised prevalence was 16.76%. Higher rates are found in Africa and low-income countries, as well as emergency surgical patients.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"284"},"PeriodicalIF":2.3,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of high-flow nasal oxygen in preventing hypoxia during Gastrointestinal endoscopy: a retrospective cohort study.","authors":"Fengli Liu, Chaojin Zhang, Xiaoqiang Wang, Bo Qi, Li Zheng, Yanhua Zhao, Weifeng Yu","doi":"10.1186/s12871-025-03155-2","DOIUrl":"10.1186/s12871-025-03155-2","url":null,"abstract":"<p><strong>Background: </strong>Hypoxia is a common complication, particularly in gastrointestinal endoscopy due to respiratory depression induced by intravenous anesthesia with the use of propofol. This study aimed to investigate the efficacy and safety of high-flow nasal oxygen in preventing hypoxia during gastrointestinal endoscopy.</p><p><strong>Methods: </strong>This single-center retrospective study included 900 patients undergoing gastrointestinal endoscopy at Renji Hospital, Shanghai Jiao Tong University School of Medicine, from June 15th 2023 to August 15th 2023. Patients were categorized into the high-flow nasal oxygen (HFNO) group using a high-flow-specific nasal cannula or the standard nasal oxygen (SNO) group using a standard nasal cannula. The primary outcome of this study was the incidence of hypoxia (mild hypoxia: 75% ≤ SpO₂ < 90% for < 60 s, severe hypoxia: SpO₂ < 75% or 75% ≤ SpO₂ < 90% for > 60 s). Secondary outcomes included the incidence of subclinical respiratory depression (90% ≤ SpO₂ < 95%) and adverse events associated with the nasal cannula. We used the propensity score matching (PSM) with a 1:1 ratio to balance the patient baseline characteristics.</p><p><strong>Results: </strong>884 patients were included in the analysis after PSM. The general characteristics of patients had no statistically significant difference between the two groups. The HFNO group demonstrated significantly better outcomes compared with SNO, including the lower incidence of hypoxia (0% vs. 5.66%, p < 0.001) and subclinical respiratory depression (1.36% vs. 12.67%, p < 0.001), and fewer adverse events associated with the nasal cannula (0% vs. 4.07%, p < 0.001). Furthermore, a multifactorial analysis identified body mass index (BMI) (HR = 1.43, 95% CI [1.17-1.76], p < 0.001) and sedation depth (HR = 10.31, 95% CI [3.68-28.88], p < 0.001) as risk factors for hypoxia in the SNO group.</p><p><strong>Conclusion: </strong>HFNO emerges as a promising approach for preventing hypoxia during gastrointestinal endoscopy, offering a simple, effective, and non-invasive means of respiratory support.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"287"},"PeriodicalIF":2.3,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}