Z. Gharari, Bagheri Khadijeh, Khodaeiaminjan Mortaza, S. Ali
{"title":"Potential Therapeutic Effects and Bioavailability of Wogonin, the Flavone of Baikal Skullcap","authors":"Z. Gharari, Bagheri Khadijeh, Khodaeiaminjan Mortaza, S. Ali","doi":"10.23937/2572-3278.1510039","DOIUrl":"https://doi.org/10.23937/2572-3278.1510039","url":null,"abstract":"The flavonoids extracted from dried roots of Scutellaria species have been used in traditional Eastern medicine for the treatment of several human ailments, including cancer and inflammation. Modern science proved that wogonin is one of the major bioactive agents responsible for the physiological activity of Baikal skullcap (Scutellaria baicalensis Georgi.), which has been regarded as a potent anticancer agent. In this mini review, anti-inflammatory, antioxidant and anticancer activity of wogonin are discussed. Besides, the bioavailability of wogonin and utilization of nanotechnology to improve the bioavailability of wogonin are also presented.","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44219713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nutritional Status and Associated Factors in Older Patients with Prostate Cancer: A Cross-Sectional Study in Two Brazilian Cities","authors":"Rodrigues Graziele Marques, Mattos Inês Echenique","doi":"10.23937/2572-3278.1510035","DOIUrl":"https://doi.org/10.23937/2572-3278.1510035","url":null,"abstract":"Background: Given the heterogeneity of the overall health status of older patient with cancer, it is recommended to conduct a multidimensional geriatric assessment (MGA) before the establishment of the treatment protocol. Nutritional status is an important part of this assessment, as it is associated to poor health outcomes in older adults with cancer. This study aims to identify factors associated with nutritional status in older adults with prostate cancer. Methods: Cross-sectional study of 538 older adults aged 60 or more, with incident prostate cancer before the beginning of the treatment at hospitals of Brazil’s Unified Health System. Nutritional status was evaluated with the Mini-Nutritional Assessment Short-Form version. Socio-demographic and clinical variables, besides some dimensions of the MGA (functionality, comorbidity and emotional condition) were evaluated. We estimated the prevalence of subjects at risk of malnutrition or malnourished and analysed the associations between nutritional status and the independent variables using prevalence ratios and Poisson’s regression with statistical significance for p value ≤ 0.05. Results: The mean age of the individuals was 69.11 ± 6.43 years and 27.1% were at risk of malnutrition or malnourished. Presence of depressive symptoms (PR 1.78; 95% CI 1.272.50), functional dependence in Basic Activities of Daily Living (PR 1.40; 95% CI 1.01-1.94) and age (PR 1.02; 95% CI 1.00-1.04) were independent factors associated with nutritional status. Conclusion: The high prevalence of patients at risk of malnutrition or malnourished and the association with functional dependence, presence of depressive symptoms and age point the importance to assessment the nutritional status in this population.","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42201750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hadjimbei Elena, Botsaris George, G. Vassilis, G PanayiotouAndrie
{"title":"Behavioral Factors Associated with Adherence to the Mediterranean Diet in Young University Students - A Cross-Sectional Study","authors":"Hadjimbei Elena, Botsaris George, G. Vassilis, G PanayiotouAndrie","doi":"10.23937/2572-3278.1510034","DOIUrl":"https://doi.org/10.23937/2572-3278.1510034","url":null,"abstract":"Objective: To investigate healthy behaviors associated with adherence to the Mediterranean diet in young adults. Methods: Behavioral factors were assessed using a selfcompleted questionnaire in 193 students enrolled in one public and one private university in Cyprus. A health habit score ranging from 0 to 5 was devised based on information on: Breakfast consumption, eating fried food, eating away from home, exercise and smoking. Adherence to the Mediterranean diet was evaluated using the validated KIDMED index. Results: Adherence to the Mediterranean diet was found to be average for the majority of young adults, with 21.8% being classified as low adherers, and 26.9% as high adherers. A higher health habit score was associated with higher adherence to the Mediterranean diet (0.614 higher average adherence (95% CI: 1.07 to 1.55) for one unit change in health habit score). About 63% of students reported consuming breakfast on a regular basis, while half consumed three or fewer meals per day. The main person responsible for preparing meals at home were the parents (63.7%). A little over half of study participants (55.4%) reported currently exercising, with only half of them feeling happy with their body weight. Tobacco use was relatively high among students (24%). Conclusion: A higher adherence to the Mediterranean diet was associated with a healthier overall behavioral pattern, including regular breakfast consumption, exercise, positive body image, higher meal frequency and water consumption, lower fried food consumption and lower consumption of meals away from home. Enhancing such positive health behaviors is likely to have an independent and lasting effect on later adulthood behaviors and health. REsEARcH ARticlE","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49567168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yilin Yoshida, Chester L Schmaltz, Jeannette Jackson-Thompson, Adam Bouras, Esmaeel Rahmani, Eduardo J Simoes
{"title":"Five Fruit and Vegetable a Day Does Not Reflect the Upward Trend of Obesity in the U.S.","authors":"Yilin Yoshida, Chester L Schmaltz, Jeannette Jackson-Thompson, Adam Bouras, Esmaeel Rahmani, Eduardo J Simoes","doi":"10.23937/2572-3278.1510038","DOIUrl":"https://doi.org/10.23937/2572-3278.1510038","url":null,"abstract":"<p><strong>Objective: </strong>After almost three decades of U.S. surveillance in fruit and vegetable (F&V) intake and obesity, it is important to evaluate their usefulness for monitoring prevention and health promotion efforts in public health. We used U.S. surveillance data to evaluate whether the 16-year trends of F&V intake, measured by the prevalence of eating five or more servings of fruits and vegetables a day (FV5/day) is related to obesity trend as measured by its prevalence in the same period. We also evaluated whether trends in the prevalence of FV5/day by important sociodemographic factors (age, race/ethnicity, etc.) could explain the findings.</p><p><strong>Study design: </strong>A secondary analysis of U.S. adults (≥ 18 years) from the Behavioral Risk Factor Surveillance System (BRFSS) (1994-2009).</p><p><strong>Methods: </strong>We categorized survey subjects for their F&V intake derived from the BRFSS six-question food frequency questionnaire into two groups: < FV5/day vs. ≥ FV5/day. Obesity was defined as BMI ≥ 30. We used logistic regressions to compute predicted prevalence of FV5/day and obesity, and to estimate the odds ratio of FV5/day by obesity and levels of sociodemographic, stratified by year.</p><p><strong>Results: </strong>Between 1994 and 2009, the prevalence of FV5/day hovered around 25% among U.S. adults, while the obesity prevalence steadily increased from 14.8% to 27.4%. As measured through odds ratio, an inverse association between FV5/day and obesity was only observed in 55+, but not in other age, racial/ethnic or education groups.</p><p><strong>Conclusions: </strong>Between 1994 and 2009, we could not confirm a decrease in the prevalence of FV5/day associated with an increase in obesity prevalence, except for age 55+ group. Known disparities in FV5/day and obesity across sociodemographic factors persisted over the study period. FV5/day may be an inappropriate measure of total calories derived from eating fruits and vegetables. Its use to measure impact of public health strategies to improve nutrition and prevent obesity may be questionable.</p>","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":"5 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38838237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scientific Evaluation of Dietary Factors in Cancer","authors":"R. Waheed, Niedzwiecki Aleksandra, R. Matthias","doi":"10.23937/2572-3278.1510029","DOIUrl":"https://doi.org/10.23937/2572-3278.1510029","url":null,"abstract":"","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44105161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Santo Adriana Bergamini Quieregatto do Espirito, S. Nestor, Laranja Sandra Maria Rodrigues
{"title":"Evaluation of the Impact of Nutritional Support on Quality of Life and Morbidity Indicators in Hemodialysis","authors":"Santo Adriana Bergamini Quieregatto do Espirito, S. Nestor, Laranja Sandra Maria Rodrigues","doi":"10.23937/2572-3278.1510026","DOIUrl":"https://doi.org/10.23937/2572-3278.1510026","url":null,"abstract":"Introduction: Protein-energy malnutrition is a predictor of morbidity and mortality in hemodialysis. Early nutritional intervention and appropriate clinical care are critical to reduce morbidity and improve quality of life in hemodialysis patients. Purpose: Evaluate the impact of nutritional assistance in hemodialysis services with full nutritional assistance (group 1) and partial nutritional assistance (group 2). Methods: A prospective cohort study of 56 patients (19 women and 37 men) followed-up for 12 months. There were 4 deaths, 4 kidney transplants, 6 transfers and 1 voluntary withdrawal, so that only 41 patients completed the study. Patients were assessed at the 3rd and 15th month of hemodialysis. Main inclusion criteria: Being on hemodialysis for at least 3 months and age ≥ 18 years. Instruments: Biochemical tests, SF-36, malnutrition-inflammation score, economic classification criteria of the Brazilian Association of Research Companies. Statistics analysis: were expressed as mean ± standard deviation, median, chi-square or Fisher’s exact test, Mann-Whitney test, “t”-Student test, Pearson’s correlation, ANOVA and Tukey’s multiple comparisons. Level of significance: p < 0.05. Results: Group 1 had a higher median age (p: 0.014). Group 2 and patients with indwelling catheter had higher median annual hospitalizations (5 and 6 days, p: 0.028 and 0.035, respectively). The malnutrition-inflammation score correlated negatively with albumin (r = -0.632, p: 0.000), and with SF-36 domains: physical functioning (r = -0.433, p: 0.001), physical aspects (r = -0.393, p: 0.003), general health (r = -0.412, p: 0.002), vitality (r = -0.338, p: 0.011), social functioning (r = -0.361, p: 0.006), emotional functioning (r = -0.278, p: 0.038), mental health (r = -0.313, p: 0.019), and positively with C-reactive protein (r = 0.479, p: 0.000). Conclusion: Results suggest that full nutritional assistance can have a positive influence, reducing morbidity and controlling nutritional disorders in hemodialysis.","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43415818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dennis Diane M, Haak Jenna, Carter Vicki, T. Michelle, C. Ian
{"title":"Characteristics of Hospitalised Patients at the Lowest and Highest Ends of the Body Mass Index Spectrum","authors":"Dennis Diane M, Haak Jenna, Carter Vicki, T. Michelle, C. Ian","doi":"10.23937/2572-3278.1510024","DOIUrl":"https://doi.org/10.23937/2572-3278.1510024","url":null,"abstract":"Background: Recent findings established that underweight (UW) and extremely obese (EO) people were over-represented in the inpatient cohort of one Australian tertiary hospital. This study aimed to describe the characteristics of these patients and identify if differences existed between this subset and the remaining cohort. Method: Single-centre retrospective case-note review of patients previously identified as being UW or EO during a 2015 prospective point prevalence study, and comparison with those who had “closer-to-normal-weight” body mass index (BMI). Results: Forty eight patient notes were reviewed (33 UW; 15 EO). The majority of UW patients were admitted under General Medicine with cancer-related illness, whereas EO patients were admitted across specialties, most commonly with a cardiovascular condition. The most frequent past medical history for both groups was a cardiovascular disorder. Compared to patients in all other BMI categories, there was no higher risk of prolonged hospital length of stay in either patient group (p = 0.94). Underweight patients had significantly higher age-adjusted Charlson co-morbidity index scores compared to the EO group (p = 0.01), and although not statistically significant, there was higher frequency of mortality (in-hospital, 28-day and 1-year post-discharge) in those UW (p = 0.54; p = 1; p = 1 respectively). Both groups demonstrated higher rates of hospital re-admission within 28 days of discharge than those reported for this hospital as a whole. Conclusion: Data presented adds to the limited evidence relating to health outcomes for patients at either end of the BMI spectrum. Decreasing hospital re-admission frequency in these groups might result in considerable cost savings in the future.","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42948310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing Iodine Status in Frontline Healthcare","authors":"Wright Ciara","doi":"10.23937/2572-3278.1510028","DOIUrl":"https://doi.org/10.23937/2572-3278.1510028","url":null,"abstract":"Introduction: Iodine is essential for the synthesis of thyroid hormones and both hypothyroidism and iodine deficiency are prevalent worldwide. Assessing iodine status in the individual is difficult. Spot urine iodine measurement, while readily available, is not accurate. However, combining the clinical picture with a brief dietary history along with this simple measurement may give further insight into the likely iodine requirements of an individual. Supporting nutritional deficiency in subclinical hypothyroidism is proposed to be helpful in reducing possible requirements for pharmacological intervention in the future although further studies are needed in this area. This is of particular importance in highrisk groups such as those trying to conceive, or patients with subfertility or recurrent miscarriage. Case description: In this case report a 66-yr-old woman with symptomatic subclinical hypothyroidism presents with a low dietary intake of iodine and a correlating low urine iodine. These three factors taken together suggested a possible iodine deficiency. Replacement of iodine with a safe and moderate amount of iodine (75 μg/day, 50% RDA) via supplement and counselling the patient to increase simple sources of iodine in the diet restored euthryoidism and resolved all symptoms. Conclusions: We propose a simple strategy for the frontline healthcare provider to estimate iodine requirements in an individual-correlating a brief dietary history, low urine iodine and suboptimal thyroid function tests. We recommend that supplementation to increase iodine is conservative and in the short-term only to avoid iodine excess. Dietary intake of iodine should be encouraged to maintain levels thereafter.","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44150286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susetyowati, H. Hamam, Hakimi Mohammad, Asdie Ahmad Husain
{"title":"Comparison of Nutrition Screening and Assessment Parameters in Predicting Length of Hospital Stay","authors":"Susetyowati, H. Hamam, Hakimi Mohammad, Asdie Ahmad Husain","doi":"10.23937/2572-3278.1510030","DOIUrl":"https://doi.org/10.23937/2572-3278.1510030","url":null,"abstract":"Background and objective: To compare the accuracy of five nutritional screening tools and to assess the most effective parameters in predicting Length of Hospital Stay (LOS). Method: Prospective cohort study in Dr. Sardjito General Hospital, the central hospital in Yogyakarta Province, Indonesia. Subjects are 326 adult patients within 48 hours of hospital admission. We using The Simple Nutrition Screening Tool (SNST), Nutritional Risk Screening-2002 (NRS2002), Malnutrition Screening Tool (MST), Malnutrition Universal Screening Tool (MUST) and Short Nutritional Assessment Questioner (SNAQ), and Nutritional Assessment (anthropometric and biochemical measurements). Results: The SNST, NRS-2002, MST, MUST, and SNAQ identified nutritional risk in 51%; 55%; 34%; 60% and 38% of the patients, respectively. The SNST obtained the highest level of discrimination (0.87) compared to NRS-2002 (0.73), MST (0.77), MUST (0.76), and SNAQ (0.78). Patients at risk of malnutrition compared to those who are not, had a lower average value of Body Mass Index (BMI), Mid Upper Arm Circumference (MUAC), albumin, Haemoglobin (Hb) and significantly higher Length of Stay (LOS) based on five Nutritional Screening Tools, except for the SNAQ. Malnutrition was associated with longer LOS with the highest value of Relative Risk (RR) were the SNST for Nutritional Screening Tools (1.76) and albumin for nutritional assessment parameters (1.37). Conclusion: All the nutritional screening and assessment parameters can predict Length of Hospital Stay in patients but, the most appropriate one is the SNST.","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48807609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Simone, Wacker Roland, W. Manfred, S. Christiane
{"title":"Absorption of Hydroxytyrosol from Different Sources and its Impact on Lipid Status in Human Subjects","authors":"S. Simone, Wacker Roland, W. Manfred, S. Christiane","doi":"10.23937/2572-3278.1510025","DOIUrl":"https://doi.org/10.23937/2572-3278.1510025","url":null,"abstract":"Background: There is growing interest in the health effects of dietary polyphenols on cardiovascular risk factors. In this context, the effect of hydroxytyrosol on lipid status was investigated in healthy subjects. Hydroxytyrosol, a polyphenol especially known from olive oil, is available on the market from different sources. Absorption from those sources is prerequisite for its effects. Methods: Here we report a study on the absorption and the effects of a pure, synthetic form of hydroxytyrosol compared to an olive extract and a placebo. The phenols hydroxytyrosol and homovanillic acid were chosen as markers in urine. The study was conducted as a mono-center, randomized, double-blind, placebo-controlled, three-way cross-over design with 30 healthy subjects. The four-week oral supplementation phases were separated by two-week wash-out phases. Results: Neither total cholesterol levels nor HDL (high-density lipoprotein)-cholesterol levels were significantly affected by the study preparations. However, a significant LDL (low-density lipoprotein)-cholesterol reduction was seen after intervention with the pure, synthetic hydroxytyrosol in comparison to placebo (p = 0.0003). LDL cholesterol levels were significantly reduced between the beginning and end of intervention with the pure hydroxytyrosol (delta LDL cholesterol -9.4 mg/dL ± 10.9 mg/dL, p = 0.0004), whereas no LDL-lowering effects were seen after the intervention with the olive extract or placebo (olive extract: delta LDL cholesterol: +2.1 mg/dL ± 15.2 mg/dL; placebo: delta LDL cholesterol: +4.1 mg/dL ± 15.4 mg/dL). The excreted amounts of hydroxytyrosol and homovanillic acid confirm the uptake of the study products in comparison to placebo (p < 0.0001). Overall the tolerability of the study products was very good. Conclusion: Our study supports the beneficial effects of pure hydroxytyrosol from a synthetic source on LDL cholesterol.","PeriodicalId":91758,"journal":{"name":"Journal of nutritional medicine and diet care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44506153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}