BMC Neurology最新文献

{"title":"Neurolathyrism in Delanta, Ethiopia: prevalence, associated factors, and social impact: a cross-sectional study.","authors":"Andualem Endrias Yesuf, Eden Efrem Mersiehazen, Bemnet Yazew Abegaz, Samson Zegeye Endale, Beyadiglign Wondimu Gebresilssie, Biniyam Jemaneh Batu","doi":"10.1186/s12883-026-04871-z","DOIUrl":"https://doi.org/10.1186/s12883-026-04871-z","url":null,"abstract":"<p><strong>Background: </strong>Neurolathyrism is an upper motor neuron disorder affecting the corticospinal tracts and causing spastic paraparesis. Linked to consuming Lathyrus sativus, it remains a global public health challenge, particularly in parts of Ethiopia. This research explored the prevalence, associated factors, and social impact of neurolathyrism among patients in the Delanta district, Ethiopia.</p><p><strong>Objective: </strong>To assess the prevalence, associated factors, and social impact of neurolathyrism among patients in the Delanta district, Ethiopia.</p><p><strong>Methods: </strong>A community-based cross-sectional study was conducted from February to March 2023 among 470 randomly selected individuals in two purposively selected kebeles of Delanta district, Amhara region. A multistage sampling technique was employed. The data were collected using a structured questionnaire after written informed consent was obtained from each participant. The collected data were cleaned and analyzed using Epi Info version 7.2 and SPSS version 26.0, respectively. Descriptive statistics and multivariable logistic regression models were used. Statistical significance was determined using P value < 0.05. Associations were measured by adjusted odds ratios (AORs). Factors with a P value of 0.2 or less in the bivariable analysis were selected for further multivariable analysis and entered a logistic regression model.</p><p><strong>Results: </strong>Of 470 participants, 56 (11.9%) reported neurolathyrism. At the population level, prevalence in two purposively selected kebeles of the Delanta district was 6.6%. Significant individual-level variables were older age (adjusted odds ratio [AOR] = 2.69; 95% confidence interval [CI] = 1.06-9.34), male sex (AOR = 3.57; 95% CI = 1.79-7.10), and inability to read (AOR = 3.13; 95% CI = 1.22-7.99). Household-level variables included family size (AOR = 2.33; 95% CI = 1.16-4.69) and farmland lease (AOR = 2.73; 95% CI = 1.23-6.06). Among neurolathyrism patients, 73% discontinued school due to lack of support, and 21.4% were divorced after disease onset.</p><p><strong>Conclusion: </strong>The prevalence of neurolathyrism is notably high in the study population. Older age, male sex, educational status, family size, and farmland lease were significantly associated with neurolathyrism.</p>","PeriodicalId":9170,"journal":{"name":"BMC Neurology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between diplopia and clinical phenotypes in spinocerebellar ataxia type 3.","authors":"Mei Zheng, Mao-Lin Cui, Wei Lin, Zhuo-Ying Huang, Bin Cai, Shi-Rui Gan","doi":"10.1186/s12883-026-04848-y","DOIUrl":"https://doi.org/10.1186/s12883-026-04848-y","url":null,"abstract":"","PeriodicalId":9170,"journal":{"name":"BMC Neurology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147653698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of mortality of Hypertensive Intracerebral Hemorrhage (HICH) patients: a single centre study.","authors":"Lisda Amalia, Shafa Triani Fadhillah, Iin Pusparini, Achmad Adam, Marda Arif Furqani","doi":"10.1186/s12883-026-04847-z","DOIUrl":"https://doi.org/10.1186/s12883-026-04847-z","url":null,"abstract":"","PeriodicalId":9170,"journal":{"name":"BMC Neurology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147644178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National mortality trends in polyneuropathies and other disorders of the peripheral nervous system in the United States, 1999-2023: a CDC WONDER database analysis.","authors":"Palwasha Asghar, Razeena Zahid, Safiullah Soomro, Arooj Ihsan Ullah, Sujata Lodh, Javeria Imran, Iftikhar Khan, Kamil Ahmad Kamil","doi":"10.1186/s12883-026-04874-w","DOIUrl":"https://doi.org/10.1186/s12883-026-04874-w","url":null,"abstract":"","PeriodicalId":9170,"journal":{"name":"BMC Neurology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic daily headache associated with nutcracker syndrome: a case report and narrative review.","authors":"Qianyao Wang, Xueyi Fan, Shufeng Zhang, Hua Li, Jilin Chen, Xin Deng, Xue Zhang, Min Li, Hairong Qian","doi":"10.1186/s12883-026-04879-5","DOIUrl":"https://doi.org/10.1186/s12883-026-04879-5","url":null,"abstract":"","PeriodicalId":9170,"journal":{"name":"BMC Neurology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147632343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiologic and clinical features of Alzheimer's disease: a hospital study based on the memory clinic in Abidjan, Côte D'ivoire, Sub-Saharan Africa.","authors":"Kouamé Léonard Kouassi, Frédérique Reine Emmanuella Adjeman Ehoulan, Affoué Marie Roxane Beuseize, N'guessan Yves Constant Broh, Ahya Nancy Tanya Essoin-De Souza, Nawa Samuel Yeo, Ange Stéphane Abbé, Mariam Doumbia-Ouattara","doi":"10.1186/s12883-026-04867-9","DOIUrl":"https://doi.org/10.1186/s12883-026-04867-9","url":null,"abstract":"","PeriodicalId":9170,"journal":{"name":"BMC Neurology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between iron deposition and emotional disorder in Parkinson's patients: a systematic review and meta-analysis.","authors":"Kaidong Chen, Binfen Xu, Yi Ji, Wanyu Hao, Ruixuan Zhang, Liujia Lu, Yao Lu, Feng Wang, Qunfeng Tang, Li Zhang, Xiangming Fang","doi":"10.1186/s12883-026-04866-w","DOIUrl":"https://doi.org/10.1186/s12883-026-04866-w","url":null,"abstract":"","PeriodicalId":9170,"journal":{"name":"BMC Neurology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemodynamic disturbances in vertebral artery dominance: a potential pathogenic mechanism in acute isolated pontine infarction.","authors":"Yanquan Yuan, Shan Wei, Shijie Xu, Jiaohao Li, Yao Zeng, Yutian Zhang, Yuxin Wang, Zhiyong Huang, Xiaolong Lin, Chun Xiao, You Li, Linfa Chen","doi":"10.1186/s12883-026-04875-9","DOIUrl":"https://doi.org/10.1186/s12883-026-04875-9","url":null,"abstract":"","PeriodicalId":9170,"journal":{"name":"BMC Neurology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of PCSK9 inhibitors on early neurological function, inflammatory factors and blood lipids in patients with acute cerebral infarction: a retrospective cohort study.","authors":"Hailong Peng, Xuan Li, Zehao Zhang, Shifang Ma, Yunong Li, Jiaqi Dai, Qin Liu, Pei Wang","doi":"10.1186/s12883-026-04838-0","DOIUrl":"https://doi.org/10.1186/s12883-026-04838-0","url":null,"abstract":"","PeriodicalId":9170,"journal":{"name":"BMC Neurology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: anti-NMDAR encephalitis with cerebellar ataxia as the initial manifestation.","authors":"Yidi Wang, Linyang Cui, Nan Zhang","doi":"10.1186/s12883-026-04861-1","DOIUrl":"https://doi.org/10.1186/s12883-026-04861-1","url":null,"abstract":"","PeriodicalId":9170,"journal":{"name":"BMC Neurology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}