Internal medicine review (Washington, D.C. : Online)最新文献

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Butantan Institute: From Snakes To Vaccines And Its Destruction Isaias Raw Butantan研究所:从蛇到疫苗及其破坏
Internal medicine review (Washington, D.C. : Online) Pub Date : 2020-01-01 DOI: 10.18103/imr.v6i3.854
I. Raw
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引用次数: 6
Forty Years of Hypothesis Conformity or Confirmation Bias in the Social Sciences 社会科学假说一致性或确认偏差的四十年
Internal medicine review (Washington, D.C. : Online) Pub Date : 2020-01-01 DOI: 10.18103/imr.v6i4.875
W. Schumm
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引用次数: 1
Global influenza vaccine distribution survey demonstrates urgency of implementation of objective 3 of WHO influenza strategy 2019-2030. 全球流感疫苗分布调查显示,迫切需要落实世卫组织2019-2030年流感战略目标3。
Internal medicine review (Washington, D.C. : Online) Pub Date : 2020-01-01 DOI: 10.18103/imr.v6i2.850
B. Palache, P. Barbosa
{"title":"Global influenza vaccine distribution survey demonstrates urgency of implementation of objective 3 of WHO influenza strategy 2019-2030.","authors":"B. Palache, P. Barbosa","doi":"10.18103/imr.v6i2.850","DOIUrl":"https://doi.org/10.18103/imr.v6i2.850","url":null,"abstract":"","PeriodicalId":91699,"journal":{"name":"Internal medicine review (Washington, D.C. : Online)","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84998622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Prescription rates and its effect on the opioid overdose death rate: implications of pharmaceutical financial incentives 处方率及其对阿片类药物过量死亡率的影响:制药财务激励的含义
Internal medicine review (Washington, D.C. : Online) Pub Date : 2019-03-01 DOI: 10.18103/IMR.V5I3.805
M. C. Wang, C. Moss, J. Oehmke, A. Schmitz, G. D'Onofrio, L. Post
{"title":"Prescription rates and its effect on the opioid overdose death rate: implications of pharmaceutical financial incentives","authors":"M. C. Wang, C. Moss, J. Oehmke, A. Schmitz, G. D'Onofrio, L. Post","doi":"10.18103/IMR.V5I3.805","DOIUrl":"https://doi.org/10.18103/IMR.V5I3.805","url":null,"abstract":"","PeriodicalId":91699,"journal":{"name":"Internal medicine review (Washington, D.C. : Online)","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76979929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of caffeine and alcohol in the formation of glucose from starch-α-Amylase reaction: Application of a two-step model 咖啡因和酒精在淀粉-α-淀粉酶反应生成葡萄糖中的作用:两步模型的应用
Internal medicine review (Washington, D.C. : Online) Pub Date : 2019-01-01 DOI: 10.18103/imr.v5i1.779
Arshad Khan
{"title":"Role of caffeine and alcohol in the formation of glucose from starch-α-Amylase reaction: Application of a two-step model","authors":"Arshad Khan","doi":"10.18103/imr.v5i1.779","DOIUrl":"https://doi.org/10.18103/imr.v5i1.779","url":null,"abstract":"","PeriodicalId":91699,"journal":{"name":"Internal medicine review (Washington, D.C. : Online)","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88780793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An exploratory study of access to evidence-based therapy for eating disorders 进食障碍循证治疗途径的探索性研究
Internal medicine review (Washington, D.C. : Online) Pub Date : 2019-01-01 DOI: 10.18103/imr.v5i4.817
A. Higgins
{"title":"An exploratory study of access to evidence-based therapy for eating disorders","authors":"A. Higgins","doi":"10.18103/imr.v5i4.817","DOIUrl":"https://doi.org/10.18103/imr.v5i4.817","url":null,"abstract":"","PeriodicalId":91699,"journal":{"name":"Internal medicine review (Washington, D.C. : Online)","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76942325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of impacted maxillary canine position using panoramic radiograph and CBCT 全景x线片与CBCT对上颌阻生犬位的比较评价
Internal medicine review (Washington, D.C. : Online) Pub Date : 2019-01-01 DOI: 10.18103/IMR.V5I3.804
Sunila Thomas
{"title":"Comparative evaluation of impacted maxillary canine position using panoramic radiograph and CBCT","authors":"Sunila Thomas","doi":"10.18103/IMR.V5I3.804","DOIUrl":"https://doi.org/10.18103/IMR.V5I3.804","url":null,"abstract":"","PeriodicalId":91699,"journal":{"name":"Internal medicine review (Washington, D.C. : Online)","volume":"179 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89625235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Comprehensive Development of a Faculty Mentorship Program at a Canadian Medical & Dental School: Policy, Program, and Five Years of Assessment 加拿大医学和牙科学校教师指导计划的全面发展:政策,计划和五年评估
Internal medicine review (Washington, D.C. : Online) Pub Date : 2019-01-01 DOI: 10.18103/IMR.V5I1.774
M. Sem, L. Johns, M. Longstaffe, M. Steele
{"title":"The Comprehensive Development of a Faculty Mentorship Program at a Canadian Medical & Dental School: Policy, Program, and Five Years of Assessment","authors":"M. Sem, L. Johns, M. Longstaffe, M. Steele","doi":"10.18103/IMR.V5I1.774","DOIUrl":"https://doi.org/10.18103/IMR.V5I1.774","url":null,"abstract":"","PeriodicalId":91699,"journal":{"name":"Internal medicine review (Washington, D.C. : Online)","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73793801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Young guns: Does age of onset of gun carrying impact violent behavior and gang membership (before/during/after first time gun carrying)? 年轻持枪者:开始持枪的年龄是否会影响暴力行为和帮派成员(在第一次持枪之前/期间/之后)?
Internal medicine review (Washington, D.C. : Online) Pub Date : 2019-01-01 DOI: 10.18103/IMR.V5I4.785
R. Spano, J. Bolland, L. Post
{"title":"Young guns: Does age of onset of gun carrying impact violent behavior and gang membership (before/during/after first time gun carrying)?","authors":"R. Spano, J. Bolland, L. Post","doi":"10.18103/IMR.V5I4.785","DOIUrl":"https://doi.org/10.18103/IMR.V5I4.785","url":null,"abstract":"","PeriodicalId":91699,"journal":{"name":"Internal medicine review (Washington, D.C. : Online)","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75635766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis. 使用实验性败血症的共病模型,雌性小鼠表现出较少的肾线粒体损伤,但更高的死亡率。
Internal medicine review (Washington, D.C. : Online) Pub Date : 2018-10-01 DOI: 10.18103/imr.v4i10.768
Lee Ann MacMillan-Crow, Philip R Mayeux
{"title":"Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis.","authors":"Lee Ann MacMillan-Crow,&nbsp;Philip R Mayeux","doi":"10.18103/imr.v4i10.768","DOIUrl":"10.18103/imr.v4i10.768","url":null,"abstract":"<p><p>Given the inherent heterogeneity of the septic patient population and possible comorbid conditions, it is not surprising that the influence of gender on incidence and outcomes are still unclear. The goal of this study was to use a clinically relevant murine model of sepsis, cecal ligation and puncture (CLP) in CD1 mice, with and without uniphrectomy as a comorbid condition to investigate possible gender differences in renal mitochondrial function and dynamics. High resolution respirometry on fresh kidney biopsies was used to measure renal respiratory complex activities. At 18h post-CLP with nephrectomy male mice showed significant reductions in complex I, II, and III activities, while females were less effected; only complex I was significantly reduced from sham mice. Taken together, our studies revealed, for the first time, gender differences in mitochondrial respiratory activity even in the absence of sepsis. We also examined expression of key mitochondrial fission and fusion proteins. In both genders and in both CLP models, protein expression of the primary fission protein, DRP1 was significantly decreased. No changes were observed in female mice in either CLP model; whereas, male mice demonstrated a slight reduction in MFN1 and the short form of OPA1 after CLP, and modest increase in MFN2 with CLP plus nephrectomy. In both genders CLP with nephrectomy produced a greater increase in serum blood urea nitrogen, a biomarker of renal injury, than without nephrectomy. However, CLP with nephrectomy produced significantly lower 96-hour survival in females. Our results suggest that the CLP nephrectomy comorbid model of sepsis may be an appropriate model to study gender differences a select group of predisposed individuals.</p>","PeriodicalId":91699,"journal":{"name":"Internal medicine review (Washington, D.C. : Online)","volume":"4 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261321/pdf/nihms-994604.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36788314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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