Pomeranian journal of life sciences最新文献

{"title":"Usefulness of aloe vera (Aloe vera) as a potential ingredient of cosmetic preparations","authors":"Anita Witaszczyk, A. Klimowicz","doi":"10.21164/pomjlifesci.970","DOIUrl":"https://doi.org/10.21164/pomjlifesci.970","url":null,"abstract":"Abstract Introduction: Skin ageing is a natural process caused by both intrinsic and extrinsic factors, such as exposure to solar radiation, smoking, environmental pollution, improper skin care, improper lifestyle, stress and lack of sleep. These factors accelerate the ageing process of the skin by impairing and limiting many of its functions. In order to protect the skin against the harmful effects of ultraviolet radiation, photoprotective preparations and antioxidants are used, which neutralize the action of free radicals affecting the abnormal homeostasis of the body. Antioxidants are the main group of ingredients used in anti-ageing prophylaxis. Many raw materials of natural origin are rich in these ingredients. The aim of the study was to assess the antioxidant activity of the aloe vera extracts and to evaluate extraction conditions including the effect of solvent used as an extractant on the observed antioxidant potential and the ability to absorb solar radiation by aloe vera (Aloe vera). Materials and methods: The material for the study consisted of alcoholic extracts prepared from the peel and flesh of aloe vera. Extracts in 40%, 70% or concentrated ethanol, methanol, n-propanol and isopropanol were used. Extracts were obtained after 15, 30 or 60 min of ultrasound-assisted extraction. Antioxidant activity was determined spectrophotometrically using the DPPH and ABTS methods, while the Folin–Ciocalteu method was used to determine total polyphenol content. Absorption spectra of the prepared extracts were taken to evaluate the absorption capacity. Results: The highest average antioxidant activity was shown by aloe leaf peel extract in 40% methanol, subjected to a 60 min extraction and determined by the DPPH method. For aloe vera leaf peel extracts tested by the DPPH and ABTS methods, the best solvent seems to be 40% methanol, while in the Folin–Ciocalteu method it was 96% ethanol. For aloe vera flesh extracts evaluated by the DPPH method, the best solvents were undiluted alcohols, while for those evaluated by the ABTS method, it was 40% methanol, and for the determination of total polyphenol content, it was 96% ethanol. If compared to the evaluated parts of the plant studied, aloe leaf peel showed the most favourable antioxidant properties of the raw materials used. The UV-VIS spectra of the majority of extracts show an absorption maximum at a wavelength of about 300 nm, which corresponds to the UVB range. Conclusion: Aloe vera is a valuable source of antioxidant components. Ultrasound-assisted extraction is a useful method to isolate antioxidant substances from plant material. The antioxidant potential is influenced by the extraction time of the raw material and the solvent used. Aloe vera leaf peel extracts showed higher antioxidant activity than extracts prepared from its flesh. It can be successfully used as a raw material in anti-ageing prevention and as a potential photoprotective ingredient.","PeriodicalId":91594,"journal":{"name":"Pomeranian journal of life sciences","volume":"30 1","pages":"76 - 87"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139344564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The dental considerations of outpatient inhalation therapy","authors":"Marcin Pasternak","doi":"10.21164/pomjlifesci.941","DOIUrl":"https://doi.org/10.21164/pomjlifesci.941","url":null,"abstract":"Abstract Inhalation is one of the routes of drug administration used in therapy. Medicines are dispersed via an aerosol spray, mist, powder or vapour that patients breathe into their airways. Depending on the intrapulmonary behaviour of each molecule of the inhaled agent, the prevailing effect obtained may be local or general. Inhaled therapy, due to its local effect, is a cornerstone of obstructive pulmonary diseases like asthma and chronic obstructive pulmonary disease (COPD), while the general effects of vaporised medical cannabis support its use in other indications (e.g. epilepsy, insomnia, spastic pain). Regardless of the purpose of use, an inhaled drug passes through the oropharynx and a major portion of its dose remains there. This paper focuses on the impact of inhaled therapy on the oral cavity, highlighting the issues important for dental practitioners. The most common indications for inhaled therapy are presented together with the devices used for this route of administration and the drugs employed in outpatient care. Particular attention is paid to oral side effects of inhaled medicines and their pathophysiology. The advisable measures for dental care of patients using inhaled therapy are presented.","PeriodicalId":91594,"journal":{"name":"Pomeranian journal of life sciences","volume":"45 1","pages":"52 - 59"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139344861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electronic analysis of mandibular movements during speech depending on the skeletal class","authors":"M. Tomasik, M. Lipski, Ryta Łagocka, Krzysztof Safranow, Monika Machoy","doi":"10.21164/pomjlifesci.954","DOIUrl":"https://doi.org/10.21164/pomjlifesci.954","url":null,"abstract":"Abstract Speech is one of the most important functions of the stomatognathic system. The aim of the study was to assess mandibular movements during speech depending on the skeletal class and the mutual relationship between the incisors. Forty-nine patients without functional disorders of the masticatory organ were examined. In subjects with skeletal class I, the mean length of condylar motion in the sagittal plane was 0.8 mm; in the case of class II, it was – 1.2 mm; and for class III, it was 0.9 mm. There was no statistically significant correlation between the examined parameters of mandibular translation movement during speech with gender or skeletal class. However, the correlations between the maximum mandibular rotation angle and the position of the incisors were statistically significant.","PeriodicalId":91594,"journal":{"name":"Pomeranian journal of life sciences","volume":"28 1","pages":"10 - 13"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139344686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Results of the surgical treatment of gastrointestinal stromal tumours: a case series","authors":"Michał Brzeziński, J. Pawlus, Jakub Jędrych, Tadeusz Sulikowski, Jarosław Lichota","doi":"10.21164/pomjlifesci.919","DOIUrl":"https://doi.org/10.21164/pomjlifesci.919","url":null,"abstract":"Abstract Gastrointestinal stromal tumours (GISTs) are rare malignant neoplasms that develop mainly in the gastrointestinal tract. They typically cause non-specific dyspeptic symptoms in the abdominal cavity or gastrointestinal bleeding. Treatment may vary depending on the location, mitotic activity and clinical manifestations of the tumour. This study analyses the cases of patients with GISTs treated at the Department of General, Minimally Invasive and Gastroenterological Surgery of the Independent Public Teaching Hospital in Szczecin, Poland, from 2017 to 2022.","PeriodicalId":91594,"journal":{"name":"Pomeranian journal of life sciences","volume":"40 1","pages":"60 - 64"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139344864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of clinical estimation of bone union in hand fractures: a preliminary report","authors":"Andrzej Żyluk","doi":"10.21164/pomjlifesci.855","DOIUrl":"https://doi.org/10.21164/pomjlifesci.855","url":null,"abstract":"Abstract An assessment of the healing of bone fractures is mainly based on X-ray confirmation of some characteristic features of fracture consolidation. This paper presents a new method of estimation of bone union of hand fractures based on examination of pain resulting from pressure of the fracture site. It was assumed that bone is united if at 2–3 weeks the fracture site is painless. The pain at the fracture site was examined in 12 patients with fractures of phalanges and metacarpals of specified configuration; an assessment was performed at the beginning of the treatment and after 2, 3, and finally at 4 weeks. All patients were treated by functional method, without any immobilization. At baseline, the mean level of pain in numeric rating scale was 6.4 and in subsequent assessments a significant reduction in pain was observed, down to 0.6 at 4 weeks. Radiological assessment at 4 weeks showed a lack of consolidation of the fracture in 8 patients and at 8 weeks in 4. Despite this, all patients demonstrated normal function of the hand and all returned to normal daily activity and to work. The results of this study demonstrate that clinical assessment of phalangeal or metacarpal fracture healing based on the lack of pain in reaction to applying pressure on the fracture site is a better and more reliable method than radiological estimation which shows bone union significantly later. The proposed clinical assessment allows patients a significantly earlier normal use of the affected hand.","PeriodicalId":91594,"journal":{"name":"Pomeranian journal of life sciences","volume":"59 1","pages":"14 - 16"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139345473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fragment reattachment of fractured anterior teeth with pulp exposure: a 10-year follow-up","authors":"Ewa Marek, Katarzyna Kot, Adam Kozłowski, Ryta Łagocka, M. Lipski","doi":"10.21164/pomjlifesci.951","DOIUrl":"https://doi.org/10.21164/pomjlifesci.951","url":null,"abstract":"Abstract Coronal fractures of the anterior teeth are a common form of dental injury. Reattachment of fractured tooth fragments using dental adhesive techniques offers some advantages, including restoration of the function, aesthetics, shape, texture, and brightness of the surface. The present report describes a clinical case of partial pulpotomy by the Cvek technique and reattachment with a 10-year clinical and radiographic follow-up in permanent maxillary central incisors with complicated crown fractures.","PeriodicalId":91594,"journal":{"name":"Pomeranian journal of life sciences","volume":"37 1","pages":"65 - 68"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139345896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of genetical factors on the risk of carpal tunnel syndrome occurrence: a review","authors":"A. Żyluk","doi":"10.21164/pomjlifesci.834","DOIUrl":"https://doi.org/10.21164/pomjlifesci.834","url":null,"abstract":"Abstract Carpal tunnel syndrome (CTS) is the most common compression neuropathy in the upper limb. Mechanical compression and local ischemia of the median nerve result in paresthesia, pain, and sensory and motoric disturbances. There are some aspects of the disease that suggest the potential role of genetic predispositions. This article presents a review of the literature about the significance of genetic factors in the etiology of CTS. It discusses the effect of selected gene mutations on constitutional and anthropometric features which may predispose to CTS. These genes are involved in the organization of an extracellular matrix architecture, as well as in bone, cartilage, and tendons development pathways. Therefore they may be potentially responsible for the observed relationship between anthropometric/constitutional factors and CTS. The findings from the studies provide reliable information on the association between genetic risk factors and the development of CTS.","PeriodicalId":91594,"journal":{"name":"Pomeranian journal of life sciences","volume":"69 1","pages":"16 - 18"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47752822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peculiarities of some candidate gene polymorphisms in Parkinson’s disease","authors":"Aleena Parveen Shaikh, Rajneesh Khurana, Nameera Parveen Shaikh, Joy Dip Barua, Ashraf Ali, I. Murvanidze, E. Saralidze, I. Nakashidze","doi":"10.21164/pomjlifesci.893","DOIUrl":"https://doi.org/10.21164/pomjlifesci.893","url":null,"abstract":"Abstract Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder among elderly individuals, after Alzheimer’s disease. This complex disorder manifests with multiple motor and non-motor features and is often diagnosed only after the onset of significant pathological symptoms. Based on the presumption that epigenetic mechanisms are involved in neurodevelopment and synaptic transmission, it is hypothesized that epigenetic alterations are closely connected to the development of PD. Several studies have reported that genetic risk factors are involved in PD susceptibilities. These factors play a prominent role in the predisposition and development of PD and may be closely linked to different metabolic pathways. In this review, we revise associations between single nucleotide polymorphisms (SNPs) and PD pathogenesis.","PeriodicalId":91594,"journal":{"name":"Pomeranian journal of life sciences","volume":"69 1","pages":"22 - 27"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46350348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Not only endoscopic third ventriculostomy – management of aqueductal stenosis associated with pathologies of the pineal region","authors":"Z. Nowaczyk, P. Kawalec, Michał Larysz, Marcin Kołodziej","doi":"10.21164/pomjlifesci.918","DOIUrl":"https://doi.org/10.21164/pomjlifesci.918","url":null,"abstract":"Abstract Pathologies of the pineal gland region are frequently encountered in daily neurosurgical practice. It is important to remember that, besides usually asymptomatic pineal gland cysts, neoplasms of a different origin may also occur in this region. The rarity of the most dangerous lesions – pineal gland apoplexy and pineal tumors – might cause problems with proper diagnosis and treatment. Their occurrence is commonly associated with symptomatic hydrocephalus caused by aqueductal stenosis. Currently, in such cases, endoscopic procedures, including endoscopic third ventriculostomy (ETV), are commonly and widely chosen as treatment options. Endoscopic procedures not only enable decompression of hydrocephalus but also further diagnosis of its cause. Herein, we present 3 case reports of endoscopic treatment with ETV performed in patients with hydrocephalus related to pineal region pathologies.","PeriodicalId":91594,"journal":{"name":"Pomeranian journal of life sciences","volume":"69 1","pages":"54 - 57"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44450675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The lethal assault, fall trauma or cardiac arrhythmia? – diagnostic difficulties associated with determining the cause of death in a patient with an ICD","authors":"Szymon Rzepczyk, P. Świderski, Bartosz Bijata, Damian Rusek, Beata Bożek, C. Żaba","doi":"10.21164/pomjlifesci.921","DOIUrl":"https://doi.org/10.21164/pomjlifesci.921","url":null,"abstract":"Abstract The number of patients with implantable cardioverter-defibrillators (ICDs) is steadily increasing. Postmortem interpretation of the data recorded and stored by the device provides vital information about the time and cause of death. In this paper, we describe a case of a 67-year-old man found on the stairs. He had pulseless electrical activity and multiple fresh injuries, notably to the head. Despite an hour-long resuscitation attempt, it was unsuccessful. The subsequent postmortem examination revealed significant myocardial hypertrophy with post-infarction scarring in the left ventricle, and no significant central nervous system injuries were observed. The patient’s ICD was dissected and submitted for analysis. Evaluation of the recorded data revealed the presence of ventricular fibrillation (VF) and tachycardia shortly before the patient was found. Analysis of all the evidence gathered during the investigation led to the conclusion that the cause of death was cardiopulmonary failure resulting from cardiac arrhythmia, and the head injury was a result of an unconscious fall down the stairs.","PeriodicalId":91594,"journal":{"name":"Pomeranian journal of life sciences","volume":"69 1","pages":"50 - 53"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43493023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}