Journal of thyroid disorders & therapy最新文献_第5页

The Safety and Efficacy of Surgery for Primary Hyperparathyroidism without Intraoperative Parathyroid Hormone Measurement in Japan 日本手术治疗原发性甲状旁腺功能亢进术中不测量甲状旁腺激素的安全性和有效性

Journal of thyroid disorders & therapy Pub Date : 2017-01-01 DOI: 10.4172/2167-7948.1000224

H. Uchida, Y. Hibi, Chikara Kagawa, Yumi Tomiie, Z. Morise

{"title":"The Safety and Efficacy of Surgery for Primary Hyperparathyroidism without Intraoperative Parathyroid Hormone Measurement in Japan","authors":"H. Uchida, Y. Hibi, Chikara Kagawa, Yumi Tomiie, Z. Morise","doi":"10.4172/2167-7948.1000224","DOIUrl":"https://doi.org/10.4172/2167-7948.1000224","url":null,"abstract":"Introduction: Primary hyperparathyroidism (PHP) is a curable disease because most patients have only one adenoma and can fully recover after adenoma removal at the location determined by preoperative imaging. However, many Japanese surgeons believe that intraoperative intact PTH measurement (IOPM) is essential to the surgery. Hence, many general surgeons in Japan are unable to perform surgeries for PHP in their local hospitals and must refer the patients to urban high volume centers that have introduced IOPM, even though they are experienced in general surgery and the surgery for PHP is technically simple and related to general surgery. So, we analyzed the relationship of surgical outcomes, with and without IOPM. Method: Between January 2007 and December 2016, 183 consecutive patients with PHP underwent surgery in our institution. We performed the surgery between 2007 and 2012 without IOPM, and starting from 2013 we performed the surgery with IOPM. We compared and evaluated the cure rate and surgical complications between patients who underwent unilateral neck exploration without IOPM with clear preoperative localization of the affected adenoma, and those who underwent any surgery with IOPM. Result: There was no significant difference in cure rate between the two groups and there were no surgical complication in either group. Conclusion: In cases where preoperative imaging is able to clearly localize the affected adenoma and an experienced general or endocrine surgeon performs the surgery, there is no significant difference in overall cure rate and surgical complications with or without IOPM. Though many hospitals in Japan currently do not perform IOPM routinely, our study may encourage many general surgeons to perform the surgery without IOPM.","PeriodicalId":91565,"journal":{"name":"Journal of thyroid disorders & therapy","volume":"6 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70841612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Value of Intra-Operative Frozen Section in Thyroid Neoplasm Management: Experience of One Center 术中冰冻切片在甲状腺肿瘤治疗中的价值:一个中心的经验

Journal of thyroid disorders & therapy Pub Date : 2017-01-01 DOI: 10.4172/2167-7948.1000222

R. Jouini, N. Abdessayed, Wafa Koubba-Mahjoub, E. B. Brahim, A. Debbiche

{"title":"The Value of Intra-Operative Frozen Section in Thyroid Neoplasm Management: Experience of One Center","authors":"R. Jouini, N. Abdessayed, Wafa Koubba-Mahjoub, E. B. Brahim, A. Debbiche","doi":"10.4172/2167-7948.1000222","DOIUrl":"https://doi.org/10.4172/2167-7948.1000222","url":null,"abstract":"Aim: To review our own experience with Frozen section (FS) in thyroid surgery and to assess its value in the management of patients with thyroid disease. Methods: This retrospective study examined the results of 1110 frozen sections of thyroid specimens analyzed over the 10 year period from 2003 through 2012 and their correlations with the final histological examination. Deferred responses were not taken into account for statistical calculations. Results: In our series, FS and final histopathological diagnosis agreed in 85.4% and disagreed in 5.5%. 9.1% of the cases were deferred. The global specificity and sensitivity of FS analysis for all histological subtypes were 99.3% and 64.7% respectively. Its sensitivity for papillary carcinoma was 61.7%, 83.3% for follicular carcinoma and 100% for anaplastic carcinoma. Discordances were due to 6 false-positive diagnoses and 55 false-negative (FN) diagnoses. 50% of FN was represented by papillary micro-carcinoma. The positive predictive value (PPV) of the FS examination was 94.4% and its negative predictive value (NPV) was 93.9%. Conclusions: Our data supports the utility of intraoperative FS in the confirmation of malignancy of thyroid nodules. It’s correlated with a high degree of specificity and an acceptable rate of sensitivity. Most of the discordances between FS and final histopathological diagnosis were explained by papillary microcarcinoma.","PeriodicalId":91565,"journal":{"name":"Journal of thyroid disorders & therapy","volume":"6 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-7948.1000222","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70841523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subacute Thyroiditis Causing Thyrotoxic Crisis: A Case Report with Literature Review 亚急性甲状腺炎致甲状腺毒性危象1例并文献复习

Journal of thyroid disorders & therapy Pub Date : 2016-11-29 DOI: 10.4172/2167-7948.1000207

K. Salam, A. Omer, Azhin Sleman

引用次数: 8

Total Thyroidectomy in North Uganda: A Cultural and Socio-economic Challenge for an African Country 北乌干达的全甲状腺切除术:一个非洲国家的文化和社会经济挑战

Journal of thyroid disorders & therapy Pub Date : 2016-08-27 DOI: 10.4172/2167-7948.1000206

G. Burali, Ogwang David Martin, F. Fiorini, G. Mannelli, Rita Giachetti, O. Gallo, R. Santoro

引用次数: 5

Computed Tomography Features of Follicular Thyroid Adenoma and Carcinoma 滤泡性甲状腺腺瘤和癌的计算机断层扫描特征

Journal of thyroid disorders & therapy Pub Date : 2016-07-20 DOI: 10.4172/2167-7948.1000205

Donghyun Kim, D. W. Kim, J. Baek, Y. J. Lee, Young Jun Cho, H. Choo, S. Lee, Y. M. Park, H. Baek, S. Jung

{"title":"Computed Tomography Features of Follicular Thyroid Adenoma and Carcinoma","authors":"Donghyun Kim, D. W. Kim, J. Baek, Y. J. Lee, Young Jun Cho, H. Choo, S. Lee, Y. M. Park, H. Baek, S. Jung","doi":"10.4172/2167-7948.1000205","DOIUrl":"https://doi.org/10.4172/2167-7948.1000205","url":null,"abstract":"Background: No previous study has investigated the computed tomography (CT) characteristics of follicular thyroid adenoma (FTA) and follicular thyroid carcinoma (FTC). This study aimed to compare the CT features of FTA and FTC. Methods: Eighty-seven consecutive patients with FTA or FTC that underwent preoperative neck CT from January 2006 to December 2013 were included. In each case, single radiologist retrospectively examined the corresponding neck CT under blinded conditions for the histopathological results. The CT features of FTA and FTC were evaluated, as well as the specific CT features for differentiating FTC from FTA. Results: After matching the CT and histopathological results, 55 FTAs and 25 FTCs in 80 patients were analyzed. No statistically significant differences were detected in patient age, gender, nodular size, or location between FTA and FTC patients. The most common CT features in both FTA and FTC included low attenuation, intraglandular configuration, smooth margin, round shape, absence of calcifications, and inhomogeneous enhancement. In particular, the prevalence of decreased, iso-, and increased enhancement was similar in both FTA and FTC. The prevalence of homogeneous attenuation in FTC was higher, whereas the prevalence of inhomogeneous attenuation in FTA was higher. The logistic regression analysis revealed no significant differences between FTA and FTC in any CT features, except for the pattern of attenuation (p = 0.002). Conclusion: No specific CT features of FTA and FTC were identified, and CT may be unhelpful for distinguishing FTC from FTA.","PeriodicalId":91565,"journal":{"name":"Journal of thyroid disorders & therapy","volume":"12 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2016-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70841770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Critical Reflection of British Thyroid Association (BTA) Guidelines for the Management of Thyroid Nodules and Cancer 对英国甲状腺协会(BTA)甲状腺结节和癌症管理指南的重要反思

Journal of thyroid disorders & therapy Pub Date : 2016-05-30 DOI: 10.4172/2167-7948.1000204

A. Kyriacou, Ermis Vogiazanos, S. Ghattamaneni

引用次数: 4

Hypothyroidism: To Screen or not to Screen, that is the Question? 甲状腺功能减退:筛查还是不筛查，这是一个问题?

Journal of thyroid disorders & therapy Pub Date : 2016-05-16 DOI: 10.4172/2167-7948.1000E126

A. Bhargava

引用次数: 1

Thyroid Metastasis from Renal Cell Carcinoma Eight Years after Total Nephrectomy 全肾切除术后8年肾癌甲状腺转移

Journal of thyroid disorders & therapy Pub Date : 2016-04-26 DOI: 10.4172/2167-7948.1000203

Coralie Mettavant, P. Saint-Eve, P. Cuny, B. Elias

引用次数: 1

Outpatient Thyroid surgery 甲状腺门诊手术

Journal of thyroid disorders & therapy Pub Date : 2016-03-30 DOI: 10.4172/2167-7948.C1.003

B. Stack

{"title":"Outpatient Thyroid surgery","authors":"B. Stack","doi":"10.4172/2167-7948.C1.003","DOIUrl":"https://doi.org/10.4172/2167-7948.C1.003","url":null,"abstract":"H is a common endocrine disorder resulting from deficiency of Thyroid hormone. In the United States and other areas of adequate iodine intake, autoimmune Thyroid disease (Hashimoto disease) is the most common cause of hypoThyroidism; we can distinguish more types of Thyroiditis with primary hypoThyroidism, goiter or without, involved in poly-glandular autoimmune syndrome. Special normal Thyroid hormones values can be followed in pregnant women. Congenital hypoThyroidism, which affects 1 of every 4000 newborns, is due to congenital mal development of the Thyroid. This disorder is included in the newborn screening panel in many countries, and it is readily treatable once detected. Cretinism refers to severe hypoThyroidism in an infant or child. HypoThyroidism can be secondary—the Thyroid gland receives insufficient stimulation secretion of thyrotropin from the pituitary gland e.g. pituitaria adenoma, pituitary radiation, congenital, postpartum condition. In tertiary hypoThyroidism, inadequate secretion of thyrotropin-releasing hormone (TRH) from the hypothalamus leads to insufficient release of TSH, which in turn causes inadequate Thyroid stimulation. HypoThyroidism may also be drug-induced or otherwise iatrogenic. The patient’s presentation may vary from asymptomatic to myxedema coma with multisystem organ failure. Deficiency of the hormone has a wide range of effects. Classic signs and symptoms may not be present, especially in younger patients. Third-generation TSH assays are readily available and are generally the most sensitive screening tool for primary hypoThyroidism. The generally accepted reference range for normal serum TSH is 0.404.2 m IU/L. For hypoThyroidism, Thyroid hormone is administered to supplement or replace endogenous production. In general, hypoThyroidism can be adequately treated with a constant daily dose of levo thyroxine (LT4).","PeriodicalId":91565,"journal":{"name":"Journal of thyroid disorders & therapy","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70843085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Evidence based nursing in management of Hypo and Hyper Thyroidism during pregnancy 妊娠期甲状腺功能低下和亢进的循证护理管理

Journal of thyroid disorders & therapy Pub Date : 2016-03-30 DOI: 10.4172/2167-7948.C1.002

Shenila Anwarali

引用次数: 2