Journal of veterinary medicine最新文献_第8页

Comparative Pharmacokinetics of Cefquinome (Cobactan 2.5%) following Repeated Intramuscular Administrations in Sheep and Goats. 绵羊和山羊反复肌注头孢醌(Cobactan 2.5%)的比较药代动力学。

Journal of veterinary medicine Pub Date : 2014-01-01 Epub Date: 2014-05-19 DOI: 10.1155/2014/949642

Mohamed El-Hewaity, Amera Abd El Latif, Ahmed Soliman, Mohamed Aboubakr

{"title":"Comparative Pharmacokinetics of Cefquinome (Cobactan 2.5%) following Repeated Intramuscular Administrations in Sheep and Goats.","authors":"Mohamed El-Hewaity, Amera Abd El Latif, Ahmed Soliman, Mohamed Aboubakr","doi":"10.1155/2014/949642","DOIUrl":"https://doi.org/10.1155/2014/949642","url":null,"abstract":"The comparative pharmacokinetic profile of cefquinome was studied in sheep and goats following repeated intramuscular (IM) administrations of 2 mg/kg body weight. Cefquinome concentrations in serum were determined by microbiological assay technique using Micrococcus luteus (ATCC 9341) as test organism. Following intramuscular injection of cefquinome in sheep and goats, the disposition curves were best described by two-compartment open model in both sheep and goats. The pharmacokinetics of cefquinome did not differ significantly between sheep and goats; similar intramuscular dose rate of cefquinome should therefore be applicable to both species. On comparing the data of serum levels of repeated intramuscular injections with first intramuscular injection, it was revealed that repeated intramuscular injections of cefquinome have cumulative effect in both species sheep and goats. The in vitro serum protein-binding tendency was 15.65% in sheep and 14.42% in goats. The serum concentrations of cefquinome along 24 h after injection in this study were exceeding the MICs of different susceptible microorganisms responsible for serious disease problems. These findings indicate successful use of cefquinome in sheep and goats. ","PeriodicalId":91135,"journal":{"name":"Journal of veterinary medicine","volume":"2014 ","pages":"949642"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/949642","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34086607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Reproductive Parameters of the Dogo Argentino Bitch. 阿根廷杜高犬母狗的生殖参数。

Journal of veterinary medicine Pub Date : 2013-01-01 Epub Date: 2013-10-28 DOI: 10.1155/2013/495975

Marina Caffaratti, Griselda González, Nora Gorla, Corina Guendulain

{"title":"Reproductive Parameters of the Dogo Argentino Bitch.","authors":"Marina Caffaratti, Griselda González, Nora Gorla, Corina Guendulain","doi":"10.1155/2013/495975","DOIUrl":"https://doi.org/10.1155/2013/495975","url":null,"abstract":"The Dogo Argentino (DA) is the first and only breed from Argentina recognized worldwide. Although its morphologic features have been well established, its normal reproductive parameters are not clearly known. The aim of this study was to determine the main DA bitch reproductive parameters. One hundred and forty-nine surveys were obtained from breeders from Córdoba province, Argentina: one for each intact DA bitch from 1 to 14 years old. The DA bitch reached puberty at an average of 8.93 months. The mean duration of vulval bleeding found in this study was 11.11 days. The clinical signs characteristic for proestrous-estrous were vulval edema (89.93%), bleeding during the time of mating (32.21%), holding the tail to the side (95.30%), and docility during mating (85.91%). DA bitches had a whelping rate of 84%. Out of 299 pregnancies, 89.30% exhibited a normal parturition, 6.69% presented dystocia, 2.68% needed Cesarean section, and 1.34% aborted. In conclusion, the reproductive parameters of the DA bitch are similar to those identified for other large breeds. DA often showed a prolonged vulval bleeding longer than proestrus. Its high whelping rate, its low incidence of dystocia, and its good maternal ability define the DA as a good reproductive breed with normal reproductive functions. ","PeriodicalId":91135,"journal":{"name":"Journal of veterinary medicine","volume":"2013 ","pages":"495975"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/495975","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34086598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A Targeted Survey for Scrapie in Jos Plateau State, Nigeria. 尼日利亚乔斯高原州痒病的针对性调查。

Journal of veterinary medicine Pub Date : 2013-01-01 Epub Date: 2013-07-31 DOI: 10.1155/2013/841978

O O Nwankiti, E I Ikeh, O A Arowolo, A J Nwankiti, M O Odugbo, T Seuberlich

{"title":"A Targeted Survey for Scrapie in Jos Plateau State, Nigeria.","authors":"O O Nwankiti, E I Ikeh, O A Arowolo, A J Nwankiti, M O Odugbo, T Seuberlich","doi":"10.1155/2013/841978","DOIUrl":"https://doi.org/10.1155/2013/841978","url":null,"abstract":"Scrapie, a disease of sheep and goats with a progressive course and fatal outcome, has not been identified in Nigeria. Anecdotal scrapie reports by livestock workers abound. Livestock diseases like scrapie form huddles in livestock economics of countries. For 8 months we surveyed for scrapie targeting emergency/casualty slaughter sheep and goats in Jos, Nigeria. We clinically examined 510 sheep and 608 goats of local breeds, aged from 12 months to 5 years. In total 31 (5.10%) goats and no sheep were clinically suspicious for scrapie. Caudal brainstem tissues of suspect animals collected postmortem were analyzed for the disease specific form of the prion protein, PrP(Sc), using Bio-Rad's TeSeE ELISA rapid test kit. No sample was positive for scrapie. Fluorescent antibody test for rabies and H&E staining on samples were carried out for differential diagnosis. These showed no pathological lesions indicative for neurological disease. While our findings do not exclude the presence of scrapie in Jos, we demonstrate that targeted sampling of small ruminants for neuroinfectious disease is feasible in developing countries, pointing to the possibility of implementing such a monitoring scheme in Nigeria to prevent economic losses in small ruminant livestock as scrapie caveats from endemic countries have shown. ","PeriodicalId":91135,"journal":{"name":"Journal of veterinary medicine","volume":"2013 ","pages":"841978"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/841978","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34152671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Effects of Essential Oils and Polyunsaturated Fatty Acids on Canine Skin Equivalents: Skin Lipid Assessment and Morphological Evaluation. 精油和多不饱和脂肪酸对犬皮肤等效物的影响:皮肤脂质评估和形态学评估。

Journal of veterinary medicine Pub Date : 2013-01-01 Epub Date: 2013-11-06 DOI: 10.1155/2013/231526

S Cerrato, L Ramió-Lluch, D Fondevila, D Rodes, P Brazis, A Puigdemont

{"title":"Effects of Essential Oils and Polyunsaturated Fatty Acids on Canine Skin Equivalents: Skin Lipid Assessment and Morphological Evaluation.","authors":"S Cerrato, L Ramió-Lluch, D Fondevila, D Rodes, P Brazis, A Puigdemont","doi":"10.1155/2013/231526","DOIUrl":"10.1155/2013/231526","url":null,"abstract":"A canine skin equivalent model has been validated for the assessment of a topical formulation effects. Skin equivalents were developed from freshly isolated cutaneous canine fibroblasts and keratinocytes, after enzymatic digestion of skin samples (n = 8) from different breeds. Fibroblasts were embedded into a collagen type I matrix, and keratinocytes were seeded onto its surface at air-liquid interface. Skin equivalents were supplemented with essential oils and polyunsaturated fatty acid formulation or with vehicle. Skin equivalents were histopathologically and ultrastructurally studied, and the three main lipid groups (free fatty acids, cholesterol, and ceramides) were analyzed. Results showed that the culture method developed resulted in significant improvements in cell retrieval and confluence. Treated samples presented a thicker epidermis with increased number of viable cell layers, a denser and compact stratum corneum, and a more continuous basal membrane. Regarding lipid profile, treated skin equivalents showed a significant increase in ceramide content (51.7 ± 1.3) when compared to untreated (41.6 ± 1.4) samples. Ultrastructural study evidenced a compact and well-organized stratum corneum in both treated and control skin equivalents. In conclusion, cell viability and ceramides increase, after lipid supplementation, are especially relevant for the treatment of skin barrier disruptions occurring in canine atopic dermatitis. ","PeriodicalId":91135,"journal":{"name":"Journal of veterinary medicine","volume":"2013 ","pages":"231526"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/231526","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34086597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Whole Body Computed Tomography with Advanced Imaging Techniques: A Research Tool for Measuring Body Composition in Dogs. 采用先进成像技术的全身计算机断层扫描:一种测量犬体成分的研究工具。

Journal of veterinary medicine Pub Date : 2013-01-01 Epub Date: 2013-10-10 DOI: 10.1155/2013/610654

Dharma Purushothaman, Barbara A Vanselow, Shu-Biao Wu, Sarah Butler, Wendy Yvonne Brown

{"title":"Whole Body Computed Tomography with Advanced Imaging Techniques: A Research Tool for Measuring Body Composition in Dogs.","authors":"Dharma Purushothaman, Barbara A Vanselow, Shu-Biao Wu, Sarah Butler, Wendy Yvonne Brown","doi":"10.1155/2013/610654","DOIUrl":"https://doi.org/10.1155/2013/610654","url":null,"abstract":"The use of computed tomography (CT) to evaluate obesity in canines is limited. Traditional CT image analysis is cumbersome and uses prediction equations that require manual calculations. In order to overcome this, our study investigated the use of advanced image analysis software programs to determine body composition in dogs with an application to canine obesity research. Beagles and greyhounds were chosen for their differences in morphology and propensity to obesity. Whole body CT scans with regular intervals were performed on six beagles and six greyhounds that were subjected to a 28-day weight-gain protocol. The CT images obtained at days 0 and 28 were analyzed using software programs OsiriX, ImageJ, and AutoCAT. The CT scanning technique was able to differentiate bone, lean, and fat tissue in dogs and proved sensitive enough to detect increases in both lean and fat during weight gain over a short period. A significant difference in lean : fat ratio was observed between the two breeds on both days 0 and 28 (P < 0.01). Therefore, CT and advanced image analysis proved useful in the current study for the estimation of body composition in dogs and has the potential to be used in canine obesity research. ","PeriodicalId":91135,"journal":{"name":"Journal of veterinary medicine","volume":"2013 ","pages":"610654"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/610654","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34152666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Seroprevalence of Leptospiral Antibodies in Canine Population in and around Namakkal. 纳玛卡尔及其周边地区犬类的钩端螺旋体抗体血清流行率。

Journal of veterinary medicine Pub Date : 2013-01-01 Epub Date: 2013-07-09 DOI: 10.1155/2013/971810

N R Senthil, K M Palanivel, R Rishikesavan

{"title":"Seroprevalence of Leptospiral Antibodies in Canine Population in and around Namakkal.","authors":"N R Senthil, K M Palanivel, R Rishikesavan","doi":"10.1155/2013/971810","DOIUrl":"10.1155/2013/971810","url":null,"abstract":"Leptospirosis is a reemerging and a complex zoonotic bacterial disease, caused by pathogenic serovars of Leptospira interrogans. A total of 124 sera samples of dogs belonging to different categories like vaccinated, unvaccinated-semiowned, and stray dogs were subjected to sampling. Microscopic agglutination test (MAT) was conducted by using Leptospira culture. Out of 42 vaccinated dogs, 24 (57%) were positive to one or more serovars. Of the 24, 22 (52.3%), 11 (26.19%), 4 (9.5%), 1 (3%), and 2 (4.7%) were positive to icterohaemorrhagiae, canicola, pomona, grippotyphosa, and autumnalis, respectively. Of the 48 unvaccinated semiowned dogs, 10 (28.8%) showed positive agglutination to one or more serovars. Of the 10 samples, 7 (14.5%), 2 (4.1%), 3 (6.2%), 3 (6.2%), and 5 (10.2%) were positive to icterohaemorrhagiae, canicola, pomona, grippotyphosa, and autumnalis, respectively. Among the 34 stray dogs, 12 showed positive agglutination to one or more leptospiral antibodies. Of the 12 samples, 6 (17.6%) showed positive agglutination to icterohaemorrhagiae, 2 (5.8%) to canicola, 5 (14.7%) to pomona, 7 (20.5%) to grippotyphosa, and 5 (4.7%) to autumnalis. This study emphasized the changing trends in the epidemiology of leptospirosis with higher prevalence of serovar L. grippotyphosa in street dogs. ","PeriodicalId":91135,"journal":{"name":"Journal of veterinary medicine","volume":"2013 ","pages":"971810"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34084313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Escherichia fergusonii Associated with Pneumonia in a Beef Cow. 与肉牛肺炎相关的弗格森埃希菌

Journal of veterinary medicine Pub Date : 2013-01-01 Epub Date: 2013-12-02 DOI: 10.1155/2013/829532

Guillermo M Rimoldi, Robert B Moeller

引用次数: 11

Epidemiological Overview of African Swine Fever in Uganda (2001-2012). 乌干达非洲猪瘟流行病学概述（2001-2012 年）。

Journal of veterinary medicine Pub Date : 2013-01-01 Epub Date: 2013-08-12 DOI: 10.1155/2013/949638

David Kalenzi Atuhaire, Sylvester Ochwo, Mathias Afayoa, Frank Norbert Mwiine, Ikwap Kokas, Eugene Arinaitwe, Rose Anna Ademun-Okurut, Julius Boniface Okuni, Ann Nanteza, Christosom Ayebazibwe, Loyce Okedi, William Olaho-Mukani, Lonzy Ojok

{"title":"Epidemiological Overview of African Swine Fever in Uganda (2001-2012).","authors":"David Kalenzi Atuhaire, Sylvester Ochwo, Mathias Afayoa, Frank Norbert Mwiine, Ikwap Kokas, Eugene Arinaitwe, Rose Anna Ademun-Okurut, Julius Boniface Okuni, Ann Nanteza, Christosom Ayebazibwe, Loyce Okedi, William Olaho-Mukani, Lonzy Ojok","doi":"10.1155/2013/949638","DOIUrl":"10.1155/2013/949638","url":null,"abstract":"African swine fever (ASF) is a contagious viral disease, which can cause up to 100% mortality among domestic pigs. In Uganda there is paucity of information on the epidemiology of the disease, hence a study was carried out to elucidate the patterns of ASF outbreaks. Spatial and temporal analyses were performed with data collected monthly by the district veterinary officers (DVOs) and sent to the central administration at MAAIF from 2001 to 2012. Additionally, risk factors and the associated characteristics related to the disease were assessed based on semistructured questionnaires sent to the DVOs. A total of 388 ASF outbreaks were reported in 59 districts. Of these outbreaks, 201 (51.8%) were reported in districts adjacent to the national parks while 80 (20.6%) were adjacent to international borders. The number of reported ASF outbreaks changed over time and by geographical regions; however, no outbreak was reported in the North-Eastern region. ASF was ranked as second most important disease of pigs, and it occurred mostly during the dry season (P = 0.01). Pig movements due to trade (OR 15.5, CI 4.9-49.1) and restocking (OR 6.6, CI 2.5-17.3) were the major risk factors. ASF control strategies should focus on limiting pig movements in Uganda. ","PeriodicalId":91135,"journal":{"name":"Journal of veterinary medicine","volume":"2013 ","pages":"949638"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34084312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Different Amounts of Supplemental Selenium and Vitamin E on the Incidence of Retained Placenta, Selenium, Malondialdehyde, and Thyronines Status in Cows Treated with Prostaglandin F2α for the Induction of Parturition. 不同剂量的硒和维生素 E 对使用前列腺素 F2α 诱导分娩的奶牛胎盘残留发生率、硒、丙二醛和甲状腺素状态的影响

Journal of veterinary medicine Pub Date : 2013-01-01 Epub Date: 2013-11-07 DOI: 10.1155/2013/867453

Ivan B Jovanović, Miljan Veličković, Dragan Vuković, Svetlana Milanović, Olivera Valčić, Dragan Gvozdić

{"title":"Effects of Different Amounts of Supplemental Selenium and Vitamin E on the Incidence of Retained Placenta, Selenium, Malondialdehyde, and Thyronines Status in Cows Treated with Prostaglandin F2α for the Induction of Parturition.","authors":"Ivan B Jovanović, Miljan Veličković, Dragan Vuković, Svetlana Milanović, Olivera Valčić, Dragan Gvozdić","doi":"10.1155/2013/867453","DOIUrl":"10.1155/2013/867453","url":null,"abstract":"The incidence of retained placenta (RP) in cows increases in cases of parturition induced by prostaglandin F2α . We analyzed the effects of different doses of supplemental selenium and vitamin E on the incidence of RP, blood selenium, plasma thyronines, and malondialdehyde concentration. Thirty-three clinically healthy, multiparous Holstein-Frisian cows were assigned to 3 groups and supplemented with a single intramuscular injection of sodium selenite (SS) and tocopherol acetate (TAc) between days 250 to 255 of gestation: control-unsupplemented; group A-10 mg SS + 400 mg TAc; group B-20 mg SS + 800 mg TAc. Parturition was induced using PGF2α not before day 275 of gestation. The RP incidence was reduced from 66.7% in the control to 38.2 and 30.8% in groups A and B, respectively. Blood selenium and glutathione peroxidase activity in treated groups were significantly higher compared to control, with no significant difference between groups A and B. Plasma malondialdehyde in group B was significantly lower than that in control and group A, while thyronines levels were not affected. Comparison of RP and non-RP cows, independently of supplement treatment, revealed higher blood selenium and glutathione peroxidase activity and lower MDA and thyroxine in non-RP animals, while triiodothyronine level did not differ. ","PeriodicalId":91135,"journal":{"name":"Journal of veterinary medicine","volume":"2013 ","pages":"867453"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34152672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sternal Aspiration of Bone Marrow in Dogs: A Practical Approach for Canine Leishmaniasis Diagnosis and Monitoring. 犬胸骨骨髓抽吸:犬利什曼病诊断和监测的实用方法。

Journal of veterinary medicine Pub Date : 2013-01-01 Epub Date: 2013-09-28 DOI: 10.1155/2013/217314

Rosa Paparcone, Eleonora Fiorentino, Silvia Cappiello, Manuela Gizzarelli, Luigi Gradoni, Gaetano Oliva, Valentina Foglia Manzillo

{"title":"Sternal Aspiration of Bone Marrow in Dogs: A Practical Approach for Canine Leishmaniasis Diagnosis and Monitoring.","authors":"Rosa Paparcone, Eleonora Fiorentino, Silvia Cappiello, Manuela Gizzarelli, Luigi Gradoni, Gaetano Oliva, Valentina Foglia Manzillo","doi":"10.1155/2013/217314","DOIUrl":"https://doi.org/10.1155/2013/217314","url":null,"abstract":"Bone-marrow aspirate material is commonly considered as one of the most sensitive tissues for a reliable diagnosis of leishmaniasis. The procedure herein described may permit less experienced veterinarians to be familiar with a quick and safe assessment method for leishmaniasis diagnosis in their patients. Animals are positioned in right lateral recumbency, and the area corresponding to the second, third, or fourth sternebra is identified and aseptically prepared. A 18-gauge needle connected to a 10 mL syringe is driven through the skin, up to the bone wall, and firmly pushed forward while rotating. Entry into the sternebra's cavity is clearly perceived by the fall of resistance offered by the cortex. Some 2,500 sternal bone-marrow samplings were safely and efficiently performed on 887 dogs of different breeds and aging from 6 months to 14 years, during eight years of clinical activity for routine diagnosis of canine leishmaniasis in pets or for the efficacy evaluation of anti-Leishmania immunobiologicals in dogs naturally exposed to parasite transmission. Most of the samples (1716) were from 387 dogs enrolled for anti-Leishmania vaccine studies. The safety of the method was particularly assessed on these dogs that as per study protocol were submitted to repeated bone-marrow aspirations (2-4 per year) in follow-up examinations. ","PeriodicalId":91135,"journal":{"name":"Journal of veterinary medicine","volume":"2013 ","pages":"217314"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/217314","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34086596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15