Journal of oral biology (Northborough, Mass.)最新文献

{"title":"Reproducibility of Manual Periodontal Probing Following a Comprehensive Standardization and Calibration Training Program.","authors":"Bryan P Fitzgerald, Charles E Hawley, Charles Q Harrold, J Steven Garrett, Alan M Polson, Thomas E Rams","doi":"10.13188/2377-987X.1000063","DOIUrl":"10.13188/2377-987X.1000063","url":null,"abstract":"<p><strong>Background: </strong>Clinical standardization and calibration training is recommended to increase the reproducibility of periodontal probing, but its impact on manual periodontal probing outcomes has received little attention. This study examined the reproducibility of manual periodontal probing performed by a periodontist after completion of a comprehensive standardization and calibration training program.</p><p><strong>Methods: </strong>A newly-educated periodontist was subjected to an individualized periodontal probing standardization and calibration training program involving approximately 24 total hours of lecture, bench-top, and clinical instruction/evaluation. Satisfactory completion of each portion of the training program required ≥ 95% intra-examiner agreement within 1 mm between initial and repeat measurements, and a ≥ 90% level of exact agreement with measurements by a \"gold standard\" examiner. The periodontist then evaluated bleeding on probing (BOP) and performed duplicate measurements of probing depth (PD) and the distance between the cementoenamel junction and gingival margin (CEJ-GM) with a manual periodontal probe on 567 periodontal sites exhibiting ≥ 5 mm PD with BOP in 39 adults. Clinical periodontal attachment level (CAL) was calculated for each site as (PD) - (CEJ-GM).</p><p><strong>Results: </strong>Intra-examiner measurement error (the standard deviation for a single measurement) was found to be 0.21 mm for PD, 0.15 mm for CEJ-GM, and 0.26 mm for CAL. Replicate assessments of PD and CAL yielded excellent exact agreement kappa scores of 0.86 and 0.87, respectively. Greater intra-examiner measurement error was found at periodontal sites with more gingival inflammation as measured by higher BOP index scores.</p><p><strong>Conclusion: </strong>These findings demonstrate that a rigorous periodontal probing standardization and calibration training program facilitates acquisition of highly reproducible PD and CAL assessments in moderate to deep inflamed periodontal pockets with a manual periodontal probe. Similar formal hands-on training should be incorporated into dental education programs and clinical research studies to improve the diagnostic performance of manual periodontal probing of the periodontium.</p>","PeriodicalId":91029,"journal":{"name":"Journal of oral biology (Northborough, Mass.)","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33502313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secretion of VEGF, TGF-B1 and IGF-1 by Dental- Derived Stem Cells under Hypoxic Conditions","authors":"P. Cooper, B. Scheven","doi":"10.13188/2377-987x.1000060","DOIUrl":"https://doi.org/10.13188/2377-987x.1000060","url":null,"abstract":"Dental-derived stem cells (DSC) are important cells in tissue regeneration following tissue destruction. One of the environmental conditions in the injured tissue is reduce in oxygen level (hypoxia) but the effect of hypoxia on the DSC is not fully elucidated. Objectives: This study aims to evaluate the effect of hypoxia on growth factor production and expression of dental-derived stem cells. Methods : Rat periodontal ligament stem cells (PDLSCs) and dental pulp stem cells (DPSCs) were cultured in serum-free media for two or three days. When the cells achieved 70% confluence, they were incubated under normoxia (21%) or hypoxia (2%) conditions, before the conditioned media (CM) that contained the cells’ secretomes were collected and compared with bone marrow stem cells (BMSCs).ELISA kits were used to analyze VEGF, TGF-β 1 and IGF-1 levels in the collected CM. The reverse transcriptase-polymerase chain reaction (RT-PCR) was then used to determine the gene expression of the growth factors. Results : Hypoxia incubation increased growth factor secretion by the dental-derived stem cells, and these findings were also supported by the gene expression analysis of VEGF and TGF-β1 . Interestingly, IGF-1 was only detected in PDLSC CM, and these data were supported by prominent IGF-I gene expression and an inverse relationship with IGF-BP1 expression by PDLSC, compared with DPSCs and BMSCs. TGF-β 1 secretion by BMSCs was not influenced by hypoxic incubation. Conclusion : Hypoxic incubation of the dental-derived stem cells alters growth factor content in the secretomes, and IGF-1 was only detected in the PDLSC secretome","PeriodicalId":91029,"journal":{"name":"Journal of oral biology (Northborough, Mass.)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66212001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of COVID-19 Pandemic on Clinic Attendance and Management of Dental Patients: Our Experience at Dental Hospital, Obafemi Awolowo University Teaching Hospitals’ Complex, Ile Ife, Nigeria","authors":"E. Oyetola","doi":"10.13188/2377-987x.1000062","DOIUrl":"https://doi.org/10.13188/2377-987x.1000062","url":null,"abstract":"Background: COVID-19 infection, declared pandemic by WHO in January 2020 constituted a public health problem due to the highly infectious nature of the disease and the subsequent lockdown imposed by the government to control the spread. Dental services delivery was severely affected. Methodology: This is a retrospective study. Subjects were consecutive patients who presented at the Dental Centre, Obafemi Awolowo University Teaching Hospital Complex from August 2019 to August 2020. Patients’ data was obtained from Oral Diagnosis Clinic records. Patients’ data obtained include sociodemographics, complaints, diagnosis and treatment given. Analysis was done using the STATA software package. Descriptive statistics was done using frequency and percentages while bivariate analysis was done using student test, p>0.05. Results: A total of 892 patients (524, 58.7% females and 368, 41.3% males) presented at the dental clinic during the study period. Their age was 41.6 (18.9) years and the majority of patients (882, 99.3%) presented on account of orofacial pain. Significant reduction of dental clinic attendance was found as 643 (72%) patients attended the clinic 6 months before pandemic and only about one third, 229 (28%) patients attended the clinic 6 months into the pandemic. Medications (72%), indirect pulp capping (73%) and oral health counseling were the frequently adopted treatment protocols. Root Canal Treatments (RCT) (1.2%) and surgical extractions were not frequent. Conclusion: Only about one-third attendance was recorded at start of Covid-19 pandemic in our centre. The management strategies at the critical times involved more of medications, indirect pulp capping and counseling","PeriodicalId":91029,"journal":{"name":"Journal of oral biology (Northborough, Mass.)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66212146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness, Challenges and Impact of COVID-19 Lockdown: Orthodontic Patient’s Perspective","authors":"Aanchal Jain","doi":"10.13188/2377-987x.1000061","DOIUrl":"https://doi.org/10.13188/2377-987x.1000061","url":null,"abstract":"Context: Owing to the increase in COVID 19 cases, a lockdown was declared in India on 24th March 2020. All the dental facilities except for emergency procedures were suspended. Due to the lockdown, the periodic visit to the Orthodontist became difficult, which would eventually affect the Orthodontic treatment. Aim: The aim of this study was to assess the awareness, challenges and impact of COVID-19 Lockdown on Orthodontic patients. Materials & Methods: A self-designed online questionnaire of 24 questions was designed and distributed among 450 participants via WhatsApp messenger and email. Statistical analysis used: Comparison of frequencies was done using chi square test. Results: The study revealed that majority patients were affected due to the pandemic and feared increase in duration of the treatment due to the same. Most common problems were loose bands/brackets and poking wire. Some faced resistance from family for visiting the Orthodontist during pandemic. Conclusions: Majority found it necessary to continue treatment even after all difficulties. Continuous reassurance to the patients by the Orthodontist is required, by doing regular follow ups. At the same time, the awareness about the pandemic should be increased amongst the patients so that precautionary measures can be taken from their side to prevent the spread while continuing their orthodontic treatment.","PeriodicalId":91029,"journal":{"name":"Journal of oral biology (Northborough, Mass.)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66212024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dentistry in Russia: Past and Presence","authors":"Sergei V. Jargin","doi":"10.13188/2377-987x.1000059","DOIUrl":"https://doi.org/10.13188/2377-987x.1000059","url":null,"abstract":"Objectives: The aim of this review was to analyze the development of dentistry in Russia since the 1970s with special reference to the diagnosis and treatment of caries. In this connection, the concept of minimally invasive dentistry is discussed. Study Design: This is a narrative review based on the Russian and international literature. Methods: The search of international literature was performed using PubMed. Russian-language publications were searched in the Internet, in libraries and the electronic database eLibrary.ru. Results: The motto of the Soviet healthcare was priority of prophylaxis, realized by medical checkups (so-called dispensarizations) at schools, factories and institutions. Initial and sometimes questionable caries was treated by dry cutting. The necessity to spare dental tissues has been undervalued. Early start of the restoration cycle, together with suboptimal quality of filling materials, caused enlargement of cavities and eventually led to fractures and extractions. Consent for the treatment was not always asked especially from children and adolescents or their parents. The overtreatment tendency of dental caries has been preserved until today. Besides, treatments potentially contributing to gingival recession are discussed. The large-scale privatization of dentistry since 1990 created new problems. Some practitioners avoid conservative treatment of advanced lesions in favor of prosthetics. Conclusion: Economical re-routing of dental practices is necessary, so that they could survive using preventive and minimally-invasive methods more extensively. Improvements in ethical standards of healthcare providers and use of foreign expertise are needed.","PeriodicalId":91029,"journal":{"name":"Journal of oral biology (Northborough, Mass.)","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66211396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"pH, Presents a New Weapon in the Battle Against COVID-19","authors":"M. Saghiri, C. Tang","doi":"10.13188/2377-987x.1000058","DOIUrl":"https://doi.org/10.13188/2377-987x.1000058","url":null,"abstract":"*Address for Correspondence: Mohammad Ali Saghiri, Director of Biomaterial and Prosthodontic Laboratory & Assistant Professor, Department of Restorative Dentistry, Rutgers School of Dental Medicine, NJ; Department of Endodontics, University of the Pacific, Arthur A. Dugoni School of Dentistry, San Francisco, California, MSB C639A-Rutgers Biomedical and Health Sciences, 185 South Orange Avenue, Newark, NJ 07103, USA, P. 973-972-7925 F. 973972-0370; E-mail: Mohammadali.saghiri@rutgers.edu","PeriodicalId":91029,"journal":{"name":"Journal of oral biology (Northborough, Mass.)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47509066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental Care of Transgenders on Long- Termhormone Therapy","authors":"","doi":"10.13188/2377-987x.1000049","DOIUrl":"https://doi.org/10.13188/2377-987x.1000049","url":null,"abstract":"Recent studies in the United States have noted that there are over a million individuals who identify as transgenders and have begun the process of hormone therapy. Such therapy regiments allow the individual to transform from the birth gender to the desired gender. The time frame of the hormone therapy extends over a lifetime and can have some health consequences for the individual. It is therefore paramount to the dentist’s understanding what the health risks of a transgender on hormonal therapy can be in order to make appropriate decisions in these patients’s dental treatment. Geraldine Weinstein* Division of General Dentistry, University of Connecticut School of Dental Medicine, USA *Address for Correspondence Geraldine Weinstein, Division of General Dentistry, 263 Farmington Ave, Suite LM031, Farmington, CT USA 060303811, USA, E-mail: gweinstein@uchc.edu Submission: 21 May, 2019 Accepted: 12 June, 2019 Published: 14 June, 2019 Copyright: © 2019 Weinstein G, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Review Article Open Access Journal of Oral Biology Avens Publishing Group Inviting Innovations J Oral Biol June 2019 Volume 6 Issue 2 © All rights are reserved by Weinstein G, et al. Avens Publishing Group Inviting Innovations","PeriodicalId":91029,"journal":{"name":"Journal of oral biology (Northborough, Mass.)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47778216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D Model Simulation andPatient Surgery in Guided Bone Regeneration","authors":"","doi":"10.13188/2377-987x.1000046","DOIUrl":"https://doi.org/10.13188/2377-987x.1000046","url":null,"abstract":"The anterior maxilla has traditionally been a challenge when it comes to successfully placing dental implants. This is due to a combination of poor bone quality, ridge atrophy and bone resorption following extraction. Many techniques are available today for the experienced surgeon to rebuild lost bone, including guided bone regeneration (GBR). Despite GBR being a predictable procedure, complications can and do arise that may compromise outcomes. The most frequent of these include membrane exposure, fenestration/dehiscence, infection, graft particle leakage, collapse of the grafted site and excessive bleeding. However, careful pre-surgical planning is crucial and will reduce risk and incidence of complications. Cone Beam Computed Tomography (CBCT) provides greater detail and has become a commonly used diagnostic tool for implant treatment planning. Patient 3D printed models can be used to gain insight and become familiar with a patient’s exact anatomy prior to the surgical procedure. Using such models can aid in reducing surgical time, limiting the amount of soft tissue manipulation, familiarizing the surgeon with the patient’s specifi c anatomy, therefore reducing the risk of intra-operative complications, and decreasing the potential for error. The purpose of this article is to report on the use of a 3D printed model to familiarize with the anatomy of the patient prior to the surgery to plan and avoid possible complications. Grisa A, Maurino CD, Valladares A, Muchhala S and Yu PY* Arthur Ashman Department of Periodontology and Implant Dentistry, New York University College of Dentistry, USA *Address for Correspondence Yu PY, Arthur Ashman Department of Periodontology and Implant Dentistry, New York University College of Dentistry, New York 10010, USA; E-mail: ycy233@nyu.edu Submission: 03 September, 2018 Accepted: 25 February, 2019 Published: 27 February, 2019 Copyright: © 2018 Grisa A, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Case Report Open Access Journal of Oral Biology Introduction Th e anterior maxilla is demanding and challenging when it comes to establishing clinical success while placing dental implants. Th is is due to a combination of esthetic expectations, poor bone quality, ridge atrophy and bone resorption following extraction. Various techniques are available today for experienced surgeons to reconstruct lost bone, such as Autologous onlay block graft s [1], allograft block graft s [2], distraction-osteogenesis and guided bone regeneration (GBR) [3,4]. Studies in animals and humans have shown that GBR is an eff ective technique to augment atrophic ridges. Despite GBR being a predictable procedure, complications can arise that may compromise the fi nal outcomes of this procedure. Th e most frequent complications include membrane exposure, fenestration or","PeriodicalId":91029,"journal":{"name":"Journal of oral biology (Northborough, Mass.)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66211839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Presentation andEvolution of Concepts and Techniques in Maxillary Immediate Loading","authors":"Shu, Wei-Ming Kuo, Maryse Manasse","doi":"10.13188/2377-987x.1000044","DOIUrl":"https://doi.org/10.13188/2377-987x.1000044","url":null,"abstract":"Immediate loading in the maxilla is often challenging because of the poor bone quality as compared to the mandible. Moreover, the bone morphology of the maxilla may oftentimes direct the vectors of forces in a non axial direction of loading, which is detrimental for the immediately loaded implants. In literature, few studies are available with more than 3 years of evaluation of immediate loading in the maxilla. While there are several clinical factors that have been recommended for the long term success of immediate loading of the maxilla, it remains a technique sensitive procedure due to the morphology and quality of the maxillary ridge. For these reasons a new screw design, screwdriver and abutment system was introduced to correct the angulation of the implants and fabricate screw retained maxillary immediate loading prostheses. This report documents the clinical results of patients with immediately loaded implants and discusses the evolution of the surgical and restorative concepts in the fully edentulous maxilla. Hafiz Adawi*, Parnward Hengjeerajaras, Ye Shi, Shu Wei Kuo and Maryse Manasse Department of Periodontology and Implant Dentistry, New York University, USA *Address for Correspondence Hafiz Adawi, Department of Periodontology and Implant Dentistry, New York University, Clinic 5W, 345 E 24th St, New York, NY 10010, USA, Tel: +1-2025692026; E-mail: haa382@nyu.edu Submission: 15 January, 2018 Accepted: 24 May, 2018 Published: 31 May, 2018 Copyright: © 2018 Adawi H, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Case Report Open Access Journal of Oral Biology","PeriodicalId":91029,"journal":{"name":"Journal of oral biology (Northborough, Mass.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46045016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alternative Caries Management Approaches in Children","authors":"","doi":"10.13188/2377-987x.1000043","DOIUrl":"https://doi.org/10.13188/2377-987x.1000043","url":null,"abstract":"Minimal intervention dentistry is a patient care concept based on etiological factors contributing to the onset of disease and its subsequent prevention. It assimilates concepts of preventing, controlling and treating oral disease hence is centered on biological solutions. Early carious lesions exhibit effects of a disease and require less invasive therapeutic strategies. This article provides an overview of the current non-surgical therapeutic interventions for incipient carious lesions like topical fluoride (toothpastes, gels and varnish), silver diamine fluoride, ITR, sealants and resin infiltration. Topical and therapeutic sealing along with restorative care effectively preserves sound dental tissue. This review article is an overview of the alternative caries management approaches in children. It aims to inform the dental practitioners about minimal intervention dentistry for facilitating the application of modern therapeutic concepts into everyday clinical practice tailored to the specific needs of a child. Saleha Shah* Aga Khan University Karachi, Karachi, Pakistan *Address for Correspondence Saleha Shah, Department of Surgery, Aga Khan University Hospital, Karachi Stadium Road, P.O. Box 3500, Karachi 74800, Pakistan, Tel: +92 301 287 5522; E-mail: saleha. shah@aku.edu Submission: 05 April, 2018 Accepted: 22 May, 2018 Published: 29 May, 2018 Copyright: © 2018 Shah S. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Review Article Open Access Journal of Oral Biology","PeriodicalId":91029,"journal":{"name":"Journal of oral biology (Northborough, Mass.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43452795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}