BMC Nephrology最新文献

{"title":"Acute kidney injury and its associated factors among patients with acute decompensated heart failure admitted to the university of Gondar Hospital, Northwest Ethiopia: a hospital-based cross-sectional study.","authors":"Yinebeb Mezgebu, Shitaye Alemu, Mohamed Abdulkadir Mohamed, Habtewold Shibru, Workagegnehu Hailu","doi":"10.1186/s12882-024-03914-2","DOIUrl":"10.1186/s12882-024-03914-2","url":null,"abstract":"<p><strong>Background: </strong>Heart failure often leads to hospitalization and can directly impact other organs, such as the kidneys. Acute kidney injury (AKI) is a common complication in patients hospitalized for acute decompensated heart failure (ADHF) and is associated with worse outcomes. However, there are limited data on the magnitude of AKI among hospitalized ADHF patients in resource-limited settings such as Ethiopia. This study sought to determine the prevalence of AKI and the factors associated with AKI in ADHF patients in Northwest Ethiopia.</p><p><strong>Method: </strong>A hospital-based cross-sectional study was conducted at the University of Gondar Hospital in Northwest Ethiopia from June 1 to September 30, 2022. A total of 239 participants were included using consecutive sampling. Demographic information was collected through patient interviews, and relevant clinical and laboratory data were obtained from the patients' medical records. The data were analyzed using STATA version 15.0. Bivariate and multivariate logistic regression analyses were carried out to identify independently associated factors of AKI among patients with ADHF. A P value < 0.05 was considered to indicate statistical significance.</p><p><strong>Results: </strong>The overall prevalence of AKI in ADHF patients was 25.1% (CI = 19.98-31.03). Older age ≥ 60 years(AOR = 2.95, 95%CI:1.34-6.21), diabetes mellitus (AOR = 9.55,95%CI:2.68-33.99),Hypertension (AOR = 2.34,95% CI:1.08-5.07), sepsis (AOR = 2.13,95%CI:1.09-4.8), use of loop diuretics (AOR = 4.03,95%CI:1.86-8.69) and previous history of AKI (AOR = 11.56,95%CI:4.02-33.26) were independently associated with the occurrence of AKI among ADHF patients.</p><p><strong>Conclusion: </strong>A quarter of the patients admitted with ADHF developed AKI. Older age; comorbid diabetes mellitus, hypertension, or sepsis; a previous history of AKI; and the use of loop diuretics were associated with the occurrence of AKI. Such clinical characteristics available at hospital admission can be used to identify patients at increased risk for developing AKI.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"25 1","pages":"461"},"PeriodicalIF":2.2,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11654373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning models predict the progression of long-term renal insufficiency in patients with renal cancer after radical nephrectomy.","authors":"Yongchao Yan, Qihang Sun, Haotian Du, Wenming Sun, Yize Guo, Bin Li, Xinning Wang","doi":"10.1186/s12882-024-03907-1","DOIUrl":"10.1186/s12882-024-03907-1","url":null,"abstract":"<p><strong>Background: </strong>Chronic Kidney Disease (CKD) is a common severe complication after radical nephrectomy in patients with renal cancer. The timely and accurate prediction of the long-term progression of renal function post-surgery is crucial for early intervention and ultimately improving patient survival rates.</p><p><strong>Objective: </strong>This study aimed to establish a machine learning model to predict the likelihood of long-term renal dysfunction progression after surgery by analyzing patients' general information in depth.</p><p><strong>Methods: </strong>We retrospectively collected data of eligible patients from the Affiliated Hospital of Qingdao University. The primary outcome was upgrading of the Chronic Kidney Disease stage between pre- and 3-year post-surgery. We constructed seven different machine-learning models based on Logistic Regression (LR), Support Vector Machine (SVM), Random Forest (RF), Extreme Gradient Boosting (XGBoost), Light Gradient Boosting Machine (Lightgbm), Gaussian Naive Bayes (GaussianNB), and K-Nearest Neighbors (KNN). The performance of all predictive models was evaluated using the area under the receiver operating characteristic curve (AUC), precision-recall curves, confusion matrices, and calibration curves.</p><p><strong>Results: </strong>Among 360 patients with renal cancer who underwent radical nephrectomy included in this study, 185 (51.3%) experienced an upgrade in Chronic Kidney Disease stage 3-year post-surgery. Eleven predictive variables were selected for further construction of the machine learning models. The logistic regression model provided the most accurate prediction, with the highest AUC (0.8154) and an accuracy of 0.787.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"25 1","pages":"450"},"PeriodicalIF":2.2,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11654346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of individualized education on learning needs of patients undergoing hemodialysis: a randomized controlled clinical trial.","authors":"Seyyede Leila Sajjadi, Mansour Ghafourifard, Hamid Tayebi Khosroshahi","doi":"10.1186/s12882-024-03886-3","DOIUrl":"10.1186/s12882-024-03886-3","url":null,"abstract":"<p><strong>Background: </strong>Individualized patient education is one of the new approaches that have attracted much attention in recent years. In line with individualized care, individualized education is designed and implemented based on the learning needs and preferences of each patient. The purpose of this study was to investigate the effect of individualized education on the learning needs of patients on hemodialysis (HD).</p><p><strong>Methods: </strong>In this single-blinded randomized clinical trial, a total of 102 patients were randomly assigned to individualized education or control groups. Patients in the intervention group (n = 51) received individualized education based on their individualized learning needs and preferences. The control group (n = 51) received routine education with brochures. The patient's learning needs were evaluated by the Patient Learning Needs Scale (PLNS) in three-time points (before the intervention, immediately after the intervention, and three months after the last session of individualized education). Data were analyzed using SPSS software (v.26). A P-value less than 0.05 was considered significant.</p><p><strong>Results: </strong>The results showed that the mean scores of total PLNS were not significantly different between the two groups before the intervention (P = 0.77). However, the mean total score of PLNS and the mean scores of seven subscales in the intervention group were lower than the control group immediately and three months after the intervention (P < 0.001).</p><p><strong>Conclusions: </strong>Implementation of the individualized patient education program can lead to decreased learning needs of patients on HD. Therefore, hemodialysis nurses could use individualized patient education as an effective education to meet the patient's needs by considering their learning needs.</p><p><strong>Trial registration: </strong>Iranian Registry of Clinical Trial, IRCT20221031056352N1, Registered on 16/2/2023.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"25 1","pages":"452"},"PeriodicalIF":2.2,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11654321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Unusual familial cystic kidney disease: combining fine radiologic and genetic evaluation to solve the case.","authors":"Sylvain Bodard, Rim Nabbout, Olivier Hélénon, Bertrand Knebelmann","doi":"10.1186/s12882-024-03900-8","DOIUrl":"10.1186/s12882-024-03900-8","url":null,"abstract":"","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"25 1","pages":"448"},"PeriodicalIF":2.2,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11636007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective multi-site examination of chronic kidney disease using longitudinal laboratory results and metadata to identify clinical and financial risk.","authors":"Mark Fung, Aya Haghamad, Elizabeth Montgomery, Kathleen Swanson, Myra L Wilkerson, Kimon Stathakos, Richard VanNess, Sarah A Nowak, Clayton Wilburn, Haluk Kavus, Mohammed Amer Swid, Nkemakonam Okoye, Yonah C Ziemba, Girish Ramrattan, Jonathan Macy, John McConnell, Mary Jane Lewis, Beth Bailey, Khosrow Shotorbani, James M Crawford","doi":"10.1186/s12882-024-03869-4","DOIUrl":"10.1186/s12882-024-03869-4","url":null,"abstract":"<p><strong>Background: </strong>A retrospective observational study was conducted at 3 health care organizations to identify clinical gaps in care for patients with stage 3 or 4 chronic kidney disease (CKD), and financial opportunity from U.S. risk adjustment payment systems. Lack of evaluation for CKD in patients with diabetes was also assessed.</p><p><strong>Methods: </strong>Outpatient longitudinal laboratory results and patient metadata available in the electronic medical record, laboratory information system, and/or laboratory billing or facility claims data for the calendar year 2021 were evaluated. Laboratory results were compared to billing data (ICD-10 codes) and risk adjustment scores including Hierarchical Condition Categories (HCC) to determine if laboratory-identified CKD was coded as a disease condition in the electronic medical record. Adults 18 to 75 years of age were included; inpatient laboratory results and pregnant individuals were excluded.</p><p><strong>Results: </strong>At the 3 institutions, 12,478 of 16,063 (78%), 487 of 1511 (32%) and 19,433 of 29,277 (66%) of patients with laboratory evidence of stage 3 or 4 CKD did not have a corresponding ICD-10 or HCC code for CKD in the electronic medical record. For patients at the 3 institutions with diabetes on the basis of an HbA1c value of ≥ 6.5%, 34,384 of 58,278 (59%), 2274 of 2740 (83%) and 40,378 of 52,440 (77%) had not undergone guideline-recommended laboratory testing for CKD during the same 12 months. Using publicly available data for calendar year 2021, an estimated 3246 of 32,398 patients (9.9%) at the 3 institutions with undocumented CKD stages 3-4 would be enrolled in Medicare Advantage or Affordable Care Act Marketplace programs. The imputed lost reimbursement under risk-adjusted payment systems for under-documentation of CKD in this subset of patients was $2.85 M for the three institutions combined, representing lost opportunity for both identification and proactive clinical management of these patients, and financial recovery for the costs of providing that care.</p><p><strong>Conclusions: </strong>Clinical laboratories can provide value beyond routine diagnostics, helping to close gaps in care for identification and management of CKD, stratifying subgroups of patients to identify risk, and capturing missed reimbursement through risk adjustment factors.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"25 1","pages":"447"},"PeriodicalIF":2.2,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fanconi syndrome with acute proximal tubular injury induced by a dietary supplement containing beni-koji: a case series report.","authors":"Masato Habuka, Michihiro Hosojima, Yusuke Yata, Kenshiro Kurumada, Moeri Yamagiwa, Masataka Yonezawa, Masanori Sudo, Hideyuki Kabasawa, Asa Ogawa, Hitomi Hama, Yumi Ito, Naofumi Imai, Suguru Yamamoto, Akihiko Saito, Shin Goto","doi":"10.1186/s12882-024-03903-5","DOIUrl":"10.1186/s12882-024-03903-5","url":null,"abstract":"<p><strong>Background: </strong>Fanconi syndrome is a disorder of the proximal tubule that leads to malabsorption of various electrolytes and substances and is a common consequence of drug-induced nephrotoxicity. However, cases of dietary supplement-induced Fanconi syndrome are rare, and detailed reports on the evaluation of renal histology in patients with this syndrome are lacking.</p><p><strong>Case presentation: </strong>We present two cases of dietary supplement-induced Fanconi syndrome that was confirmed by kidney biopsy. Based on their medical history and laboratory and histological findings, both cases were diagnosed as acute proximal tubular injury caused by ingestion of a lipid-lowering dietary supplement containing beni-koji leading to Fanconi syndrome. After discontinuation of the dietary supplement and correction of dehydration and electrolyte imbalance, renal function completely recovered in one case but progressed to chronic kidney disease in the other.</p><p><strong>Conclusions: </strong>Clinicians should consider dietary supplement-induced Fanconi syndrome as a differential diagnosis in patients who become ill while taking a dietary supplement. Kidney biopsy is useful for diagnosing acute tubular injury with Fanconi syndrome and investigating its pathogenesis. Patients who have developed dietary supplement-induced Fanconi syndrome require long-term monitoring to detect and prevent progression to chronic kidney disease.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"25 1","pages":"446"},"PeriodicalIF":2.2,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CKD in reproductive-aged women: a call for early nephrology referral and multidisciplinary care.","authors":"Nityasree Srialluri, Sumeska Thavarajah","doi":"10.1186/s12882-024-03864-9","DOIUrl":"10.1186/s12882-024-03864-9","url":null,"abstract":"<p><p>Chronic Kidney Disease (CKD) affects millions globally, with a notable impact on biological females of reproductive age. This population faces specific issues such as fertility concerns, complex contraceptive decisions, and complications related to pregnancy that can exacerbate CKD. Given the increasing prevalence of CKD among young men and women owing to rising rates of hypertension, obesity, and diabetes, there is a need for early and tailored interventions among women of childbearing age. Current Kidney Disease Improving Global Outcomes (KDIGO) guidelines suggest nephrology referral primarily for advanced CKD stages or significant proteinuria. However, women at any CKD stage may face complex pregnancy-related decisions and increased risks that are not adequately addressed by these guidelines, warranting early specialty care. This review explores the distinct needs of women of reproductive age with CKD, identifies gaps in the existing management framework, and advocates for earlier and more comprehensive nephrology involvement. By focusing on preconception planning, risk factor management, adverse pregnancy outcomes, and existing disparities in care, this review seeks to improve understanding of the needs of women of reproductive age with CKD and calls for a shift towards more proactive, nephrology-driven care.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"25 1","pages":"444"},"PeriodicalIF":2.2,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A liver transplant patient developed renal injury on tacrolimus and experienced worsening renal function and rhabdomyolysis after switching to sirolimus: a case report.","authors":"Chang Gao, Zhi-Yu Chen, Liang Ma, Shen-Ju Gou","doi":"10.1186/s12882-024-03874-7","DOIUrl":"10.1186/s12882-024-03874-7","url":null,"abstract":"<p><p>Renal impairment and rhabdomyolysis are rare in transplant patients receiving sirolimus. We report the case of a 54-year-old male who underwent liver transplantation and was initially treated with tacrolimus, mycophenolate mofetil, and glucocorticoids for immunosuppression. After the development of renal dysfunction, tacrolimus was replaced with sirolimus. However, one month after taking sirolimus, the patient's renal function continued to deteriorate, and rhabdomyolysis developed one and a half months later. Serum analysis indicated high sirolimus concentration, whereas renal histopathology revealed acute tubular injury and interstitial arteriopathy. After reducing the dosage of sirolimus, the patient's creatine kinase levels returned to normal, and renal function improved. Two years after discharge, the patient's renal function had recovered. This case highlights the importance of monitoring sirolimus blood concentrations in clinical practice, because elevated drug concentrations can lead to renal dysfunction and rhabdomyolysis as adverse reactions. Further investigations into the pathogenic mechanisms of sirolimus-induced renal dysfunction and rhabdomyolysis may contribute to clinical practice.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"25 1","pages":"445"},"PeriodicalIF":2.2,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular autonomic neuropathy in chronic kidney disease: a study of kidney biopsy cases.","authors":"Hideaki Kuno, Go Kanzaki, Rina Oba, Takaya Sasaki, Kotaro Haruhara, Kentaro Koike, Nobuo Tsuboi, Takashi Yokoo","doi":"10.1186/s12882-024-03879-2","DOIUrl":"https://doi.org/10.1186/s12882-024-03879-2","url":null,"abstract":"<p><strong>Background: </strong>The interplay between cardiac and kidney functions is mediated by the autonomic nervous system. Cardiovascular autonomic neuropathy (CAN) is a well-documented dysfunction of this system, with heart rate variability (HRV) serving as the principal diagnostic tool. CAN is recognized as a prognostic marker for adverse kidney outcomes in diabetic kidney disease (DKD). However, the pathogenesis of CAN in patients with nondiabetic chronic kidney disease (CKD) remains underexplored. This study elucidated the prevalence of CAN and its clinicopathologic characteristics in patients with nondiabetic CKD.</p><p><strong>Methods: </strong>This cross-sectional analysis evaluated 165 nondiabetic CKD patients who underwent kidney biopsy from 2020 to 2023. HRV was quantified using the coefficient of variation of the RR interval (CVRR). CAN was diagnosed based on the CVRR and defined using the CVRR reference value-derived by defining the age and sex-dependent lower normal limits as the 2.5 percentile point of the distribution of the CVRR values in healthy individuals.</p><p><strong>Results: </strong>The median patient age was 47.0 (34.0-57.0) years, and 50.9% were male. The median estimated glomerular filtration rate was 65.0 (42.0-85.0) mL/min/1.73m², and the CVRR was 3.5 (2.4-4.7)% and 16 patients (9.7%) were diagnosed with CAN. CAN was frequently associated with kidney dysfunction, dyslipidemia, and advanced interstitial fibrosis/tubular atrophy (IF/TA). Multivariable analysis revealed that IF/TA was associated with CVRR, independent of established risk factors for CAN (P = 0.045).</p><p><strong>Conclusions: </strong>The prevalence of CAN diagnosed using the CVRR in this nondiabetic CKD cohort was 9.7%, which is four times higher than that in healthy individuals. Nondiabetic CKD patients with CAN was associated with advanced IF/TA.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"25 1","pages":"440"},"PeriodicalIF":2.2,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11610099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-efficacy, social support and oral health-related quality of life in patients with kidney transplantation and under hemodialysis.","authors":"Bero Luke Vincent Ernst, Deborah Kreher, Daniel Patschan, Rainer Haak, Thomas Ebert, Jonathan de Fallois, Gerhard Schmalz","doi":"10.1186/s12882-024-03889-0","DOIUrl":"10.1186/s12882-024-03889-0","url":null,"abstract":"<p><strong>Background: </strong>Aim of this questionnaire-based cross-sectional study was to compare self-efficacy, social support, oral hygiene-related self-efficacy (OHRSE) and oral health-related quality of life (OHRQoL) between patients under chronic hemodialysis (HD) and patients after kidney transplantation (KTx) as well as a healthy comparison group (HC).</p><p><strong>Methods: </strong>Patients under HD were recruited during their routine outpatient dialysis therapy, KTx patients during their maintenance appointment and HC patients during their regular dental check-up in the dental clinic. General self-efficacy, the OHRSE, social support (F-SozU-K14) and the OHRQoL (OHIP-G5) were assessed by specific validated questionnaires. The survey was performed by one experienced dentist.</p><p><strong>Results: </strong>44 HD, 40 KTx and 45 HC patients were included, between which the age and gender distribution was comparable (p > 0.05). With a median of 1.5 [IQR: 0-3], HD patients showed higher OHIP-G5 than the participants in KTx group (p < 0.01). Similarly, a significant difference was found between KTx (0, [0-0.5]) and HC (0, [0-3]; p < 0.01). HD patients showed a lower sum score of OHRSE, tooth-brushing, interdental-cleaning and dental-visit self-efficacy than the HC (p < 0.01). Similarly, HD patients had a lower sum score of OHRSE, tooth-brushing and dental-visit self-efficacy than the KTx group (p < 0.01). Moreover, the KTx group had a lower interdental-cleaning self-efficacy (p < 0.01) and sum score (p = 0.02) than the HC. The sum score of the general self-efficacy was comparable between the three groups (p = 0.19). The F-SozU-K14 revealed higher values in KTx (65.40 ± 5.33) compared with HD (60.95 ± 9.28) and HC group (61.71 ± 9.24; p = 0.03). Only in the KTx group, a significant association between F-SozU-K14 and OHIP-G5 was revealed (p = 0.05).</p><p><strong>Conclusions: </strong>Patients under HD show a reduced OHRSE compared to KTx and HC and a slightly reduced OHRQoL compared to KTx patients. While general self-efficacy was comparable between groups, social support of HD patients was lower than of KTx patients. The OHRSE and OHRQoL might receive increased attention in dental care of HD patients.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"25 1","pages":"441"},"PeriodicalIF":2.2,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11610369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142766078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}