BMC NephrologyPub Date : 2025-06-18DOI: 10.1186/s12882-025-04250-9
Mohamed Mamdouh Elsayed, Marwa Ahmed Abdelrahman, Abdelrazik Mohamed Sorour, Islam Ghanem Rizk, Mohamed Aly Abdelhalim Hassab
{"title":"Correction: Sodium zirconium cyclosilicate versus sodium polystyrene sulfonate for treatment of hyperkalemia in hemodialysis patients: a randomized clinical trial.","authors":"Mohamed Mamdouh Elsayed, Marwa Ahmed Abdelrahman, Abdelrazik Mohamed Sorour, Islam Ghanem Rizk, Mohamed Aly Abdelhalim Hassab","doi":"10.1186/s12882-025-04250-9","DOIUrl":"10.1186/s12882-025-04250-9","url":null,"abstract":"","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"26 1","pages":"287"},"PeriodicalIF":2.2,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC NephrologyPub Date : 2025-06-18DOI: 10.1186/s12882-025-04249-2
Yan Cai, Qingqing You, Weina Jiang, Xuyan Liu, Leping Shao
{"title":"Correction: Dental amalgam associated with SAPHO syndrome and IgA nephropathy: a case report and literature review.","authors":"Yan Cai, Qingqing You, Weina Jiang, Xuyan Liu, Leping Shao","doi":"10.1186/s12882-025-04249-2","DOIUrl":"10.1186/s12882-025-04249-2","url":null,"abstract":"","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"26 1","pages":"288"},"PeriodicalIF":2.2,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC NephrologyPub Date : 2025-06-17DOI: 10.1186/s12882-025-04216-x
Lauren O Fergus, Meryl Waldman, Monica D Hall, Lynn Vining, Jillian Hall, Tina Liu, Yuzhou Zhang, Patrick J Walker, Richard J H Smith, Carla M Nester
{"title":"Correction: Pregnancy outcomes in C3 glomerulopathy: a retrospective review.","authors":"Lauren O Fergus, Meryl Waldman, Monica D Hall, Lynn Vining, Jillian Hall, Tina Liu, Yuzhou Zhang, Patrick J Walker, Richard J H Smith, Carla M Nester","doi":"10.1186/s12882-025-04216-x","DOIUrl":"10.1186/s12882-025-04216-x","url":null,"abstract":"","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"26 1","pages":"286"},"PeriodicalIF":2.2,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12175368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC NephrologyPub Date : 2025-06-13DOI: 10.1186/s12882-025-04229-6
Nina Katharina Friedrich, Nico Schmitt, Helena Hruby, Christiane Kugler
{"title":"Self-management interventions for adult haemodialysis patients: a scoping review of randomized controlled trials.","authors":"Nina Katharina Friedrich, Nico Schmitt, Helena Hruby, Christiane Kugler","doi":"10.1186/s12882-025-04229-6","DOIUrl":"10.1186/s12882-025-04229-6","url":null,"abstract":"<p><strong>Background: </strong>Effective self-management is crucial for individuals undergoing haemodialysis to prevent complications, which can lead to morbidity and mortality. However, among this population self-management behaviours are often inadequate. To improve patient outcomes interventions that promote and enhance self-management behaviours are essential.</p><p><strong>Objective: </strong>This study aimed to provide an overview of the current body of evidence from randomized controlled trials (RCTs) on self-management interventions for haemodialysis patients. First, we aimed to present the outcomes investigated, their corresponding measurement tools and the significant results of each study. Second, we examined the presence of various self-management components and activities within the interventions. We aimed to identify new, underrepresented, and absent self-management components and activities found in the interventions.</p><p><strong>Methods: </strong>Following the scoping review process, a systematic literature search was conducted across six databases (MedLine All, Emcare, CINAHL, PsycINFO, Web of Science, Cochrane) to identify relevant studies. The search focused on RCTs involving adult haemodialysis patients. The review utilized the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statements for Scoping Reviews (PRISMA-ScR) and the Joanna Briggs Institute (JBI) approach. The included studies were required to address either self-management theories or self-management support interventions. Data were synthesized using a tabular format. The findings were analysed using content analysis based on the self-management concept.</p><p><strong>Results: </strong>Overall, fourteen articles from eight countries were included. The findings illustrate the broad thematic scope of self-management interventions. Most frequent intervention outcomes were 'quality of life', 'self-management' and 'self-efficacy'. The most used instrument was 'Strategies used by people to promote health' for measuring self-care self-efficacy. All authors of the included studies reported significant results of the intervention. The content analysis identified commonly employed self-management components and activities for haemodialysis patients, such as 'emotion regulation', 'medication adherence', and 'diet management'. It revealed underrepresented (infection control), absent (smoking cessation), and new (stress management) self-management dimensions.</p><p><strong>Conclusion: </strong>This innovative scoping review represents the first comprehensive overview of self-management intervention outcomes, their measurements, and significant results while simultaneously highlighting the complex self-management components and activities that haemodialysis patients must navigate on a daily basis. The identified gaps and opportunities underscore important areas for future intervention development.</p><p><strong>Clinical trial number: </strong>Not applicable.<","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"26 1","pages":"285"},"PeriodicalIF":2.2,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12166570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC NephrologyPub Date : 2025-06-08DOI: 10.1186/s12882-025-04183-3
Ramazan Daniş, Savaş Öztürk, İsmail Koçyiğit, Jehat Kılıç, Merve Civan, Tuncay Şahutoğlu, Dilek Torun, Engin Onan, Ahmet Alper Kıykım, Simal Köksal Cevher, Gürsel Yıldız, Zeynep Ebru Eser, Fatma Betül Güzel, Süleyman Karaköse, Tolga Yıldırım, Mehmet Polat, Ebru Gök Oğuz, Ali Gürel, Yasemin Coşkun Yavuz, Hasan Kayabaşı, Zehra Eren, Mehmet Rıza Altıparmak, Nurhan Seyahi, Mehmet Küçüksu, Sibel Gökçay Bek, Esra Akçalı, İrem Pembegül, Zeki Aydın, Elif Arı Bakır, Saliha Yıldırım, Sabahat Ecder, Mehmet Horoz, Funda Sarı, Yavuz Ayar, Murat Tuğcu, Ayça İnci, Numan Görgülü, Nedim Yılmaz Selçuk, Gülizar Şahin, Cuma Bülent Gül, Hamat Dheir, Özdem Kavraz, Abdülkadir Ünsal, Sedat Üstündağ, Ali Rıza Odabaş, Serhan Tuğlular
{"title":"Pre-earthquake kidney function is a predictor of outcomes in earthquake-related crush syndrome.","authors":"Ramazan Daniş, Savaş Öztürk, İsmail Koçyiğit, Jehat Kılıç, Merve Civan, Tuncay Şahutoğlu, Dilek Torun, Engin Onan, Ahmet Alper Kıykım, Simal Köksal Cevher, Gürsel Yıldız, Zeynep Ebru Eser, Fatma Betül Güzel, Süleyman Karaköse, Tolga Yıldırım, Mehmet Polat, Ebru Gök Oğuz, Ali Gürel, Yasemin Coşkun Yavuz, Hasan Kayabaşı, Zehra Eren, Mehmet Rıza Altıparmak, Nurhan Seyahi, Mehmet Küçüksu, Sibel Gökçay Bek, Esra Akçalı, İrem Pembegül, Zeki Aydın, Elif Arı Bakır, Saliha Yıldırım, Sabahat Ecder, Mehmet Horoz, Funda Sarı, Yavuz Ayar, Murat Tuğcu, Ayça İnci, Numan Görgülü, Nedim Yılmaz Selçuk, Gülizar Şahin, Cuma Bülent Gül, Hamat Dheir, Özdem Kavraz, Abdülkadir Ünsal, Sedat Üstündağ, Ali Rıza Odabaş, Serhan Tuğlular","doi":"10.1186/s12882-025-04183-3","DOIUrl":"10.1186/s12882-025-04183-3","url":null,"abstract":"<p><strong>Background: </strong>The devastating earthquakes in Kahramanmaraş, Türkiye, in February 2024, caused extensive trauma and loss of lives, causing unique challenges in the management of earthquake-related crush syndrome. The current study investigates the prognostic value of pre-earthquake kidney function for mortality prediction in patients diagnosed with crush syndrome.</p><p><strong>Methods: </strong>A multi-center retrospective analysis was performed using data from 469 patients treated at 46 nephrology clinics. Pre-earthquake Kidney function, defined by serum creatinine and estimated glomerular filtration rate (eGFR) levels, was obtained from pre-earthquake health records. Clinical findings, laboratory parameters, complications, and survival probabilities were analyzed. Multivariate Cox regression was used to identify independent predictors of in-hospital mortality.</p><p><strong>Results: </strong>The mean age of participants was 42.56 ± 16.92 years (Non-survivors: 50.46 ± 20.03 years, Survivors: 42.34 ± 16.80 years (p = 0.172)). The in-hospital mortality rate was 2.8%. Non-survivors exhibited significantly higher pre-earthquake creatinine levels than survivors (1.04 ± 0.61 mg/dL vs. 0.77 ± 0.33 mg/dL, p = 0.03), with lower eGFR (85.2 ± 34.7 mL/min/1.73 m² vs. 115.8 ± 39.4 mL/min/1.73 m², p = 0.008). Compared with survivors, non-survivors had higher incidences of AKI (92.3% vs. 61.6%, p = 0.037) and more severe metabolic disturbances, including hyperkalemia (5.41 ± 1.72 mmol/L vs. 5.13 ± 0.98 mmol/L, p = 0.008). Regression analysis revealed that pre-earthquake creatinine (HR: 9.121, 95% CI: 2.686-30.970, p < 0.001) and potassium levels at admission (HR: 3.338, 95% CI: 1.540-7.232, p = 0.002) were independent predictors of mortality.</p><p><strong>Conclusions: </strong>Pre-earthquake kidney function significantly predicts mortality in crush syndrome patients, highlighting the importance of baseline kidney assessment in disaster preparedness.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"26 1","pages":"284"},"PeriodicalIF":2.2,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147298/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC NephrologyPub Date : 2025-06-06DOI: 10.1186/s12882-025-04196-y
P Y M Leung, A S Graver, M Katerelos, A Skene, J B Whitlam, D A Power, P F Mount
{"title":"Glycolytic control proteins in urinary extracellular vesicles are elevated during kidney transplant T cell-mediated rejection.","authors":"P Y M Leung, A S Graver, M Katerelos, A Skene, J B Whitlam, D A Power, P F Mount","doi":"10.1186/s12882-025-04196-y","DOIUrl":"10.1186/s12882-025-04196-y","url":null,"abstract":"<p><strong>Background: </strong>A priority in kidney transplant management is the ability to monitor allograft health accurately, frequently and less-invasively. Metabolic reprogramming from fatty acid oxidation to glycolysis has been associated with kidney injury. Given the histological localisation of T cell-mediated rejection (TCMR) to the tubulointerstitium, we hypothesised that expression of glycolytic control proteins contained in urinary extracellular vesicles (UEV) may increase during TCMR.</p><p><strong>Methods: </strong>In this prospective observational study, urine samples were collected from kidney transplant recipients prior to indication biopsy. UEV were separated by differential ultracentrifugation. Vesicle markers, glycolytic control proteins and CD3 were assayed by immunoblotting. Differences in protein detection were compared across biopsy diagnoses (TCMR versus not) and Banff lesion scores.</p><p><strong>Results: </strong>51 paired urine and biopsy samples from 43 subjects were included. The TCMR group comprised of 6 cases of TCMR and 1 borderline TCMR. The remaining 44 samples comprised a \"No TCMR\" group. There was significant increase in phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) (p = 0.018) in TCMR compared to No TCMR, and similarly when tubulitis (p = 0.037) and interstitial inflammation (p = 0.047) were present. Total inflammation score ≥ 1 was associated with increases in PFKFB2 (p = 0.027), PFKFB3 (p = 0.090) and PFKFB4 (p = 0.0098). Interstitial fibrosis was associated with increased PFKFB2 (p = 0.0045) and PFKFB3 (p = 0.045). CD3 + UEV did not correlate with TCMR diagnosis. When combining the four glycolytic control proteins governing the phosphofructokinase-1 step of glycolysis (PFK-L, PFKFB2, PFKFB3 and PFKFB4), presence of ≥ 3 markers discriminated TCMR with ROC AUC of 0.73 (95% CI 0.50-0.96).</p><p><strong>Conclusion: </strong>Increased rate-limiting enzymes of glycolysis in UEV were detected in association with tubulointerstitial inflammation and fibrosis. This suggests altered energy metabolism in the form of increased renal glycolysis occurring in the tubular epithelium, consistent with findings in native kidney injury. Further work is required to evaluate whether this could serve as a non-invasive strategy to study pathology in kidney transplantation.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"26 1","pages":"283"},"PeriodicalIF":2.2,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigating the impact of interdisciplinary training programs on self-efficacy and life satisfaction among Hemodialysis patients: a randomized controlled clinical trial.","authors":"Mohadese Bahmani, Mostafa Bijani, Zhila Fereidouni, Azizallah Dehghan, Amene Modreki","doi":"10.1186/s12882-025-04218-9","DOIUrl":"10.1186/s12882-025-04218-9","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease represents a critical healthcare challenge globally, with significant implications for the patient well-being. Emerging evidence suggests that innovative educational interventions may substantially improve patients' self-efficacy and life satisfaction. This study aimed to evaluate the effects of an interdisciplinary training program on self-efficacy, and life satisfaction among hemodialysis patients in southern Iran.</p><p><strong>Methods: </strong>This is a randomized controlled trial research without blinding included 100 hemodialysis patients who met the inclusion criteria participants from July to October 2024. Those who agreed to participate were randomly allocated into two groups: an intervention group (n = 50) and a control group (n = 50). The educational content validity was developed collaboratively through coordinated meetings with an interdisciplinary team that included a nephrologist, a dietitian, a nurse, a social worker, a spiritual counselor, and a psychologist. Based on this framework, a five-session interdisciplinary educational program was designed for the intervention group. Each session lasted 30 to 45 min. Data collection utilized two validated instruments: Diener Life Satisfaction Scale and Sherer General Self-Efficacy Questionnaire. These were administered at three critical time points-baseline (pre-intervention), immediately post-intervention, and three months following the training. The Shapiro-Wilk test evaluated the normality of quantitative data. The independent-samples t-test (or Mann-Whitney test) were performed to compare the basic data of the two groups. The post-intervention data were compared between study groups using ANCOVA and in this test the baseline information was considered as covariate. Also, the researchers employed repeated measures analysis of variance to measure changes in the patients' self-efficacy, and life satisfaction mean scores over time and between the two groups, with a p-value < 0.05 considered statistically significant.</p><p><strong>Results: </strong>The sample comprised 66 male and 34 female participants, with a mean (SD) age of 54.4 (10.6) years in the intervention group and 55.0 (10.2) years in the control group. Initially, no statistically significant differences were detected among the groups across demographic characteristics. Following the interdisciplinary training program, the self-efficacy and life satisfaction differences in mean scores in the intervention group were significantly higher than the control group as measured immediately and three months after the intervention (p < 0.05).</p><p><strong>Conclusion: </strong>This study provided compelling evidence for the transformative potential of interdisciplinary educational approaches to enhance the patient outcomes. The significant improvements in self-efficacy and life satisfaction suggest that targeted, holistic training programs can be a powerful tool in patient care str","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"26 1","pages":"280"},"PeriodicalIF":2.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12143035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC NephrologyPub Date : 2025-06-05DOI: 10.1186/s12882-025-04192-2
Jordan A Parsons, Fergus J Caskey, Jonathan Ives
{"title":"Correction: \"You can't put your luck on people\": a qualitative study of family views on the best interests decision-making process concerning adult kidney care in England.","authors":"Jordan A Parsons, Fergus J Caskey, Jonathan Ives","doi":"10.1186/s12882-025-04192-2","DOIUrl":"10.1186/s12882-025-04192-2","url":null,"abstract":"","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"26 1","pages":"281"},"PeriodicalIF":2.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12142990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC NephrologyPub Date : 2025-06-05DOI: 10.1186/s12882-025-04220-1
Pernille de-la-Motte, Victoria Baekager Just Jensen, Maria Højer Bergum, Frank Holden Mose, Dinah Sherzad Khatir, Jeanette Finderup
{"title":"Shared decision making and dialysis choice: an observational longitudinal cohort study.","authors":"Pernille de-la-Motte, Victoria Baekager Just Jensen, Maria Højer Bergum, Frank Holden Mose, Dinah Sherzad Khatir, Jeanette Finderup","doi":"10.1186/s12882-025-04220-1","DOIUrl":"10.1186/s12882-025-04220-1","url":null,"abstract":"<p><strong>Background: </strong>The 'Shared decision making and dialysis choice' intervention has been part of usual care at two hospitals in Denmark since 2018. The objective was to describe dialysis modality choice and outcomes for patients with kidney failure who received a shared decision making intervention.</p><p><strong>Methods: </strong>Retrospective observational longitudinal cohort study design was used. Data were collected from 2018 to 2023 on 484 patients with kidney failure from one regional and one university hospital. The exposure was a shared decision making intervention for dialysis choice. The predictors were frailty, estimated glomerular filtration rate (eGFR), comorbidity, Body Mass Index (BMI), ethnicity, marital status and smoking. The outcomes were home-based dialysis, time, concordance, and death. Fisher's exact tests and Wilcoxon rank-sum tests assessed whether choice of dialysis modality differed significantly. Aalen-Johansen estimation assessed time from the shared decision making intervention to treatment initiation, concordance between chosen and initiated treatment, and mortality before treatment initiation. Logistic regression and Cox proportional hazards evaluated the patient characteristics predicting these three outcomes.</p><p><strong>Results: </strong>After the intervention, 68% chose home-based dialysis, while 32% chose center-based dialysis. With significant differences, more patients aged ≤ 70 years, at the university hospital, and living with a partner chose home-based dialysis. Half of the patients initiated treatment within 11 months, and predictors for initiating dialysis later than 11 months were age ≥ 70 years and eGFR > 15 ml/min/1.73 m². 83% of the patients received the treatment chosen, and predictors for concordance were center-based dialysis, regional hospital, and very mild to mild frailty. 12% of the patients died before treatment initiation, predicted by very mild to severe frailty and BMI < 25 kg/m².</p><p><strong>Conclusions: </strong>A high proportion of patients chose a home-based treatment after receiving the intervention and initiated their preferred dialysis choice. 50% of patients received the intervention 11 months before initiating dialysis, and few patients died before initiating dialysis. Routinely assessing frailty and BMI prior to intervention could possibly improve patient pathways. Complete follow-up for all patients was not ensured.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"26 1","pages":"282"},"PeriodicalIF":2.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12142963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC NephrologyPub Date : 2025-06-04DOI: 10.1186/s12882-025-04204-1
Hosna Karami, Mahmoud Rahmati, Parvin Abbasi
{"title":"Investigating the relationship between perceived social support and resilience in patients undergoing hemodialysis: a cross-sectional study.","authors":"Hosna Karami, Mahmoud Rahmati, Parvin Abbasi","doi":"10.1186/s12882-025-04204-1","DOIUrl":"10.1186/s12882-025-04204-1","url":null,"abstract":"<p><strong>Background: </strong>Long-term hemodialysis significantly impacts the lives of patients and their families, creating a range of psychosocial and economic challenges. Social support and resilience are critical in enabling patients to navigate these difficulties and restore balance. This study investigated the relationship between perceived social support and resilience in patients undergoing hemodialysis.</p><p><strong>Methods: </strong>This inferential cross-sectional study was conducted from April to July 2022, involving patients undergoing hemodialysis at two major centers in western Iran. Three hundred patients were selected through convenience sampling based on specific inclusion and exclusion criteria. Data were gathered using a demographic information form, the Multidimensional Scale of Perceived Social Support, and the Connor-Davidson Resilience Scale. The data were analyzed using SPSS version 24 software, employing descriptive and analytical statistical methods.</p><p><strong>Results: </strong>The results indicated a significant positive correlation between perceived social support and patients' resilience (r = 0.391, p = 0.001). Multivariable linear regression analysis revealed that resilience was significantly associated with perceived social support (β = 0.384, p = 0.001), educational level (β = 0.151, p = 0.018), marital status (β = 0.139, p = 0.036), gender (β = 0.134, p = 0.014), and income level (β = 0.128, p = 0.025).</p><p><strong>Conclusion: </strong>The study findings demonstrate a strong positive correlation between perceived social support and resilience in patients undergoing hemodialysis. Therefore, health professionals are recommended to enhance resilience through psychosocial interventions (e.g., support groups and counseling) and family empowerment models.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9089,"journal":{"name":"BMC Nephrology","volume":"26 1","pages":"278"},"PeriodicalIF":2.2,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12139138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}