Transfusion alternatives in transfusion medicine : TATM最新文献_第3页

Editorial: the Janus face of oxygen 社论:氧气的双面神

Transfusion alternatives in transfusion medicine : TATM Pub Date : 2010-12-01 DOI: 10.1111/J.1778-428X.2011.01153.X

J. Meier

引用次数: 0

Hyperoxia in the treatment of traumatic brain injury and stroke 高氧治疗外伤性脑损伤及脑卒中

Transfusion alternatives in transfusion medicine : TATM Pub Date : 2010-12-01 DOI: 10.1111/J.1778-428X.2011.01147.X

C. Tolias

引用次数: 1

Therapeutic effects of hyperoxic ventilation during shock: OXYGEN TREATMENT IN SHOCK 休克期间高氧通气的治疗效果:休克中的氧气治疗

Transfusion alternatives in transfusion medicine : TATM Pub Date : 2010-12-01 DOI: 10.1111/J.1778-428X.2010.01146.X

H. Bitterman

{"title":"Therapeutic effects of hyperoxic ventilation during shock: OXYGEN TREATMENT IN SHOCK","authors":"H. Bitterman","doi":"10.1111/J.1778-428X.2010.01146.X","DOIUrl":"https://doi.org/10.1111/J.1778-428X.2010.01146.X","url":null,"abstract":"SUMMARY \u0000 \u0000Decreased availability of oxygen to metabolizing cells is a major feature of circulatory shock that leads to tissue damage and multiple organ dysfunctions. A wish to alleviate tissue hypoxia underlies the common clinical use of hyperoxic ventilation in shock. Yet, this straightforward approach is met by skepticism that is based on the potential pro-inflammatory effects of hyperoxia and the acknowledged roles of reactive oxygen species and oxidative stress in tissue injury. A steadily growing body of experimental data indicates that hyperoxia exerts an extensive profile of physiologic and pharmacologic effects that improve tissue oxygenation, exert anti-inflammatory and antibacterial effects, augment tissue repair mechanisms, and may also decrease oxidative stress during shock. The currently available preclinical information on the benefits of early use of safe regimens of hyperoxic ventilation alone or in combination with other commonly employed modalities sets the stage for renewal of careful clinical evaluation of oxygen therapy in resuscitation of circulatory shock.","PeriodicalId":90375,"journal":{"name":"Transfusion alternatives in transfusion medicine : TATM","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1778-428X.2010.01146.X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63396986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Editorial: the role of intravenous iron in heart failure – beyond anemia correction 社论:静脉注射铁在心力衰竭中的作用——超越贫血矫正

Transfusion alternatives in transfusion medicine : TATM Pub Date : 2010-12-01 DOI: 10.1111/J.1778-428X.2011.01152.X

A. Maniatis

引用次数: 0

The effects of hyperoxic ventilation in the treatment of myocardial infarction 高氧通气在心肌梗死治疗中的作用

Transfusion alternatives in transfusion medicine : TATM Pub Date : 2010-12-01 DOI: 10.1111/J.1778-428X.2010.01144.X

C. Conti

{"title":"The effects of hyperoxic ventilation in the treatment of myocardial infarction","authors":"C. Conti","doi":"10.1111/J.1778-428X.2010.01144.X","DOIUrl":"https://doi.org/10.1111/J.1778-428X.2010.01144.X","url":null,"abstract":"SUMMARY \u0000 \u0000Everyone supports the use of oxygen therapy to treat hypoxia secondary to acute myocardial infarction. However, the literature is confusing on the subject of supplemental oxygenation of patients with normal oxygen saturation and uncomplicated acute myocardial infarction, despite the fact that controlled randomized human studies have failed to support the need for supplemental oxygen in the uncomplicated patient. Both normobaric and hyperbaric oxygen must be recognized as a vasoactive substance and thus be considered a drug to which the patient may have an adverse response, particularly in patients whose oxygen saturation is 95% or greater, for example, coronary vasoconstriction. \u0000 \u0000 \u0000 \u0000The level of evidence for the use of normobaric oxygenation in uncomplicated acute myocardial infarction patients who were not hypoxemic is based on expert opinion, case studies and ‘standard of care’. Hyperbaric oxygen therapy has not been shown to be beneficial in human studies. \u0000 \u0000 \u0000 \u0000Most studies of the use of supplemental oxygen in humans with acute myocardial infarction were performed prior to modern aggressive medical therapy and current thrombolytic or percutaneous coronary intervention therapy. Perhaps a randomized clinical trial in patients with normal oxygen saturations and modern therapy will shed some light on the subject.","PeriodicalId":90375,"journal":{"name":"Transfusion alternatives in transfusion medicine : TATM","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1778-428X.2010.01144.X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63397392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of administration of iron isomaltoside 1000 in patients with chronic heart failure. A pilot study 异麦芽糖苷铁1000在慢性心力衰竭患者中的应用效果。一项初步研究

Transfusion alternatives in transfusion medicine : TATM Pub Date : 2010-12-01 DOI: 10.1111/J.1778-428X.2010.01145.X

P. Hildebrandt, N. Bruun, O. Nielsen, E. Pantev, Farzad Shiva, L. Videbæk, G. Wikström, L. Thomsen

{"title":"Effects of administration of iron isomaltoside 1000 in patients with chronic heart failure. A pilot study","authors":"P. Hildebrandt, N. Bruun, O. Nielsen, E. Pantev, Farzad Shiva, L. Videbæk, G. Wikström, L. Thomsen","doi":"10.1111/J.1778-428X.2010.01145.X","DOIUrl":"https://doi.org/10.1111/J.1778-428X.2010.01145.X","url":null,"abstract":"SUMMARY \u0000Intravenous iron preparations have shown benefit in patients with chronic heart failure (CHF) and iron deficiency. Iron isomaltoside 1000 (Monofer) is a novel intravenous iron compound with low immunological activity of the isomaltoside and low free-iron-related toxicity. The primary objective of this open-label, non-comparative, multicenter pilot study was to test the safety of iron isomaltoside 1000 in patients with CHF and anemia. In addition, its effect on markers of iron deficiency, anemia and on quality of life was assessed. Twenty patients with CHF and iron deficiency anemia attended six visits during the 8-week study period. Iron isomaltoside 1000 was infused at baseline (mean dose 868 mg, range 650–1000 mg). No treatment-related adverse reactions, no acute anaphylactic or delayed allergic reactions and no clinically significant changes in routine clinical laboratory safety tests or vital signs were observed. Markers of iron deficiency, anemia and quality of life improved from baseline with increase in mean value of 49% at 4 weeks in overall quality of life. Iron isomaltoside 1000 administered as a fast single infusion without a test dose to patients with CHF improved quality-of-life assessments and was well tolerated in this pilot safety study.","PeriodicalId":90375,"journal":{"name":"Transfusion alternatives in transfusion medicine : TATM","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1778-428X.2010.01145.X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63396972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 33

Can we reduce routine blood ordering in spinal surgery 我们能在脊柱手术中减少常规抽血吗

Transfusion alternatives in transfusion medicine : TATM Pub Date : 2010-12-01 DOI: 10.1111/J.1778-428X.2011.01148.X

V. Kouritas, S. Graham, Gautam Marwah, S. Papastefanou

{"title":"Can we reduce routine blood ordering in spinal surgery","authors":"V. Kouritas, S. Graham, Gautam Marwah, S. Papastefanou","doi":"10.1111/J.1778-428X.2011.01148.X","DOIUrl":"https://doi.org/10.1111/J.1778-428X.2011.01148.X","url":null,"abstract":"SUMMARY \u0000 \u0000Spinal reconstruction can be associated with major blood loss; because of the non existence of ordering guidelines, blood products are ordered preoperatively in excessive quantities. The aim of our study was to investigate the efficiency of our ordering routine. \u0000 \u0000 \u0000 \u0000The records of 205 spinal surgery patients, over a period of 3 years were reviewed. The crossmatched to transfused (C-T) ratio was calculated for each pathology group and the safe number of units transfused was determined. \u0000 \u0000 \u0000 \u0000A total of 929 units were crossmatched, whereas 84 patients required transfusion. In all, 404 units were not used (C-T ratio = 1.8). The greatest number of unused but cross matched units was observed in painful back surgery (C-T ratio = 3.9, P < 0.01 vs. other pathologies). For all the other pathology groups (scoliosis, tumor and fracture) fewer units can be ordered, except in neuromuscular scoliosis group (6 units used on average for each case). For spinal fusion, artificial disc replacement or simple discectomy, a group and save routine is adequate. \u0000 \u0000 \u0000 \u0000In conclusion, less blood can be ordered for spinal surgery, except for cases of neuromuscular scoliosis. The blood units crossmatched for painful back surgery, were more than actually needed. With technological advancement historical blood crossmatching policies may need re-evaluation.","PeriodicalId":90375,"journal":{"name":"Transfusion alternatives in transfusion medicine : TATM","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1778-428X.2011.01148.X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63397101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Perioperative optimization of oxygen delivery: PERIOPERATIVE OXYGEN DELIVERY 围手术期氧输送优化:围手术期氧输送

Transfusion alternatives in transfusion medicine : TATM Pub Date : 2010-09-30 DOI: 10.1111/J.1778-428X.2010.01134.X

B. Conte, J. L’hermite, J. Ripart, J. Lefrant

引用次数: 6

Hyperchloremic acidosis during plasma expansion: FLUIDS AND HYPERCHLOREMIC ACIDOSIS 血浆扩张期间的高氯血症酸中毒:体液和高氯血症酸中毒

Transfusion alternatives in transfusion medicine : TATM Pub Date : 2010-09-30 DOI: 10.1111/J.1778-428X.2010.01135.X

B. Tavernier, Sébastien Faivre, C. Bourdon

引用次数: 2

Metabolic effects of plasma expanders: METABOLIC EFFECTS OF PLASMA EXPANDERS 血浆扩张剂的代谢作用:血浆扩张剂的代谢作用

Transfusion alternatives in transfusion medicine : TATM Pub Date : 2010-09-30 DOI: 10.1111/J.1778-428X.2010.01137.X

L. Muller, J. Lefrant

{"title":"Metabolic effects of plasma expanders: METABOLIC EFFECTS OF PLASMA EXPANDERS","authors":"L. Muller, J. Lefrant","doi":"10.1111/J.1778-428X.2010.01137.X","DOIUrl":"https://doi.org/10.1111/J.1778-428X.2010.01137.X","url":null,"abstract":"SUMMARY \u0000 \u0000 \u0000All plasma expanders exert metabolic effects – either favorable effects such as correction of hypovolemia-induced lactic acidosis or renal failure, or unwanted adverse effects such as hypotonic solution-induced hyponatremia, acid-base disorders such as hyperchloremic acidosis and effects related to buffers associated with plasma expanders (lactate, acetate). The use of crystalloids alone is associated with a risk of interstitial fluid overload responsible for organ dysfunction in anesthesia and intensive care. The exclusive and prolonged use of high doses of colloids is associated with a risk of severe renal failure. Crystalloids appear to be sufficient to correct tissue hypoperfusion induced by moderate hypovolemia. Alternating prescription of isotonic saline and balanced plasma expanders should be able to avoid the metabolic complications of these two types of crystalloids. Administration of colloids is safe when the recommended maximum doses are observed. When administration of a colloid is indicated, a latest generation hydroxyethyl starch solution appears to present the best benefit/risk ratio.","PeriodicalId":90375,"journal":{"name":"Transfusion alternatives in transfusion medicine : TATM","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1778-428X.2010.01137.X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63397260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5