{"title":"血浆扩张期间的高氯血症酸中毒:体液和高氯血症酸中毒","authors":"B. Tavernier, Sébastien Faivre, C. Bourdon","doi":"10.1111/J.1778-428X.2010.01135.X","DOIUrl":null,"url":null,"abstract":"SUMMARY \n \nMany crystalloid and colloid plasma expanders can induce ‘hyperchloremic’ metabolic acidosis. This finding, first reported over 50 years ago, has received renewed interest following the recent availability of ‘balanced’ solutions. Several questions must be addressed and answered before making recommendations with regard to the use of these solutions. Do acidosis and hyperchloremia always go hand in hand? What is the clinical impact of hyperchloremic acidosis? Are all ‘balanced’ plasma expanders equivalent? Should isotonic saline-based plasma expanders be abandoned? Several elements of reflection are summarized in this brief review. On the basis on the currently available literature, it is not objectively possible to propose clear-cut guidelines.","PeriodicalId":90375,"journal":{"name":"Transfusion alternatives in transfusion medicine : TATM","volume":"11 1","pages":"3-9"},"PeriodicalIF":0.0000,"publicationDate":"2010-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1778-428X.2010.01135.X","citationCount":"2","resultStr":"{\"title\":\"Hyperchloremic acidosis during plasma expansion: FLUIDS AND HYPERCHLOREMIC ACIDOSIS\",\"authors\":\"B. Tavernier, Sébastien Faivre, C. Bourdon\",\"doi\":\"10.1111/J.1778-428X.2010.01135.X\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"SUMMARY \\n \\nMany crystalloid and colloid plasma expanders can induce ‘hyperchloremic’ metabolic acidosis. This finding, first reported over 50 years ago, has received renewed interest following the recent availability of ‘balanced’ solutions. Several questions must be addressed and answered before making recommendations with regard to the use of these solutions. Do acidosis and hyperchloremia always go hand in hand? What is the clinical impact of hyperchloremic acidosis? Are all ‘balanced’ plasma expanders equivalent? Should isotonic saline-based plasma expanders be abandoned? Several elements of reflection are summarized in this brief review. On the basis on the currently available literature, it is not objectively possible to propose clear-cut guidelines.\",\"PeriodicalId\":90375,\"journal\":{\"name\":\"Transfusion alternatives in transfusion medicine : TATM\",\"volume\":\"11 1\",\"pages\":\"3-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1111/J.1778-428X.2010.01135.X\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Transfusion alternatives in transfusion medicine : TATM\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/J.1778-428X.2010.01135.X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transfusion alternatives in transfusion medicine : TATM","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/J.1778-428X.2010.01135.X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hyperchloremic acidosis during plasma expansion: FLUIDS AND HYPERCHLOREMIC ACIDOSIS
SUMMARY
Many crystalloid and colloid plasma expanders can induce ‘hyperchloremic’ metabolic acidosis. This finding, first reported over 50 years ago, has received renewed interest following the recent availability of ‘balanced’ solutions. Several questions must be addressed and answered before making recommendations with regard to the use of these solutions. Do acidosis and hyperchloremia always go hand in hand? What is the clinical impact of hyperchloremic acidosis? Are all ‘balanced’ plasma expanders equivalent? Should isotonic saline-based plasma expanders be abandoned? Several elements of reflection are summarized in this brief review. On the basis on the currently available literature, it is not objectively possible to propose clear-cut guidelines.