Journal of gastroenterology and hepatology research最新文献_第6页

Differences In quality of life between patients with functional dyspepsia after esophagogastroduodenoscopy with empiric treatment and placebo 经验性治疗与安慰剂对食道胃十二指肠镜检查后功能性消化不良患者生活质量的影响

Journal of gastroenterology and hepatology research Pub Date : 2021-01-01 DOI: 10.53388/ghr2021-06-034

S. Sumardjo, N. Ratnasari, P. Bayupurnama

{"title":"Differences In quality of life between patients with functional dyspepsia after esophagogastroduodenoscopy with empiric treatment and placebo","authors":"S. Sumardjo, N. Ratnasari, P. Bayupurnama","doi":"10.53388/ghr2021-06-034","DOIUrl":"https://doi.org/10.53388/ghr2021-06-034","url":null,"abstract":"Functional dyspepsia is a common health problem found in society. Few of multifactorial aspects which become the underlying cause of functional dyspepsia are anxiety and psychosocial problem. Esophagogastroduodenoscopy (EGD) examination can display exact information to patient with functional dyspepsia and expected to increase patient’s quality of life. It is still necessary to evaluate the advantages of EGD examination in improving patient’s quality of life.A Randomized double blind controlled trial was conducted to compare between group of patients who have been given an empiric treatment(Proton pump inhibitor and prokinetic agents) and other who have been given a placebo for 2 weeks after underwent EGD examination in patients with functional dyspepsia. The primary outcome of this study is the decrease of NDI-SF score on both of groups at the end of study.A total of 42 patients (22 in EGD+placebo group [Group I] and 20 in EGD + treatment group[Group II]) were enrolled. NDI-SF score decreased significantly in both groups, Group I (26.23±8.43 vs 19.59±7.62, P=0.001) and Group II (27.32±7.57 vs 19.21±5.68, P=0.002), 15 days after underwent EGD examination. NDI-SF score improvement between two groups 15 days after EGD was not significantly different (P=0.814). This study showed improvement in quality of life of patients whom diagnosed with functional dyspepsia after EGD examination in both groups. This improvement was not significantly different between two groups and showed the placebo effect of EGD on functional dyspepsia patient.","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"103 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80639777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the Effective Mechanism of Fructus Aurantii Immaturus in the Treatment of Chronic Atrophic Gastritis Based on Network Pharmacology and Molecular Docking Technology 基于网络药理学和分子对接技术分析枳实治疗慢性萎缩性胃炎的作用机制

Journal of gastroenterology and hepatology research Pub Date : 2021-01-01 DOI: 10.53388/ghr2021-03-028

Jing-Nuan Wu, Yingbing Mei, Nierui Huang, Sisi Li

引用次数: 0

Explanatory Factors for Severe Acute Malnutrition in 6 - 59 months of age Patients Admitted in the Therapeutic Nutritional Unit of N’Djamena, Chad 乍得恩贾梅纳营养治疗中心收治的6 - 59个月患者严重急性营养不良的解释因素

Journal of gastroenterology and hepatology research Pub Date : 2021-01-01 DOI: 10.53388/ghr2021-06-033

Neguemadji Ngardig, Kankeu Tonpouwo, Maryan Gelle, Alla-hein Appolinaire, B. Boy, N. Hange, Manoj Kumar, Sana Irfan, Lemingar Dessinsa, M. Kezia

{"title":"Explanatory Factors for Severe Acute Malnutrition in 6 - 59 months of age Patients Admitted in the Therapeutic Nutritional Unit of N’Djamena, Chad","authors":"Neguemadji Ngardig, Kankeu Tonpouwo, Maryan Gelle, Alla-hein Appolinaire, B. Boy, N. Hange, Manoj Kumar, Sana Irfan, Lemingar Dessinsa, M. Kezia","doi":"10.53388/ghr2021-06-033","DOIUrl":"https://doi.org/10.53388/ghr2021-06-033","url":null,"abstract":"Introduction: Globally Severe acute malnutrition(SAM) affects more than 29 million children under the age of five. Demographic and Health Survey and Multiple Indicators in Chad (EDS-MICS) of 2014-2015 survey found an acute malnutrition level of 13% out of which 9% was moderate and 4% was severe. The Causes of SAMS are multifactorial, relating to multiple domains such as society, culture, environment, education, livelihoods, agriculture, water, hygiene, etc. Despite this established evidence, the evidence of parental knowledge is unknown. Objective: The objective of our study was to determine the explanatory factors of SAM and its level of knowledge, understanding by the parents. Materials and Methods: A prospective descriptive study was conducted in 238 children aged 6-59 months admitted to therapeutic nutritional unit Alerte Santé of Ndjamena from November 15 to December 30, 2017. Results: During the study, the male sex (58.8%), the age group of 12-17 months (26.9%) and 6-8 months (24.4%) were the most represented and are the majorities in the urban area (72.3%). We were able to identify the various explanatory factors among which the level of education of mothers (62.2%), exclusive breastfeeding (2.3%), the food taboo (81%) are not insignificant. Malnutrition would be decompensated by the breakdown of food access (59%) and digestive diseases (74.8%) and respiratory diseases (73.5%). We found that parents have poor knowledge of malnutrition (87%). Conclusion: A good understanding of these main factors of malnutrition by parents might help to effectively combat severe acute malnutrition.","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"118 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87947797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Focus on microvascular invasion in hepatocellular carcinoma: a pathological perspective 肝细胞癌微血管侵袭的病理观察

Journal of gastroenterology and hepatology research Pub Date : 2021-01-01 DOI: 10.53388/ghr2021-03-031

Han Wang, Wen-Ling Cong

引用次数: 0

Hospital Reconversion of the Gastrointestinal Endoscopy Service at The National Medical Center November 20 Issste During the Covid-19 Pandemic 新冠肺炎大流行期间，国家医疗中心胃肠内窥镜服务的医院改造11月20日发布

Journal of gastroenterology and hepatology research Pub Date : 2020-12-31 DOI: 10.24966/GHR-2566/100030

Teresa Gómez

引用次数: 0

The Liver’s Fate Amid COVID-19 Pandemic COVID-19大流行期间肝脏的命运

Journal of gastroenterology and hepatology research Pub Date : 2020-12-21 DOI: 10.17554/j.issn.2224-3992.2020.09.977

M. B. Bestari, S. Abdurachman

引用次数: 1

The Effects of Nutrients on Stress and Aggression: Integrative Approaches to Behavioral and Emotional Modification 营养物质对应激和攻击的影响:行为和情绪调节的综合方法

Journal of gastroenterology and hepatology research Pub Date : 2020-12-21 DOI: 10.17554/j.issn.2224-3992.2020.09.975

Vimala Alagappan, Ripal Shah, Robert C. Meisner

{"title":"The Effects of Nutrients on Stress and Aggression: Integrative Approaches to Behavioral and Emotional Modification","authors":"Vimala Alagappan, Ripal Shah, Robert C. Meisner","doi":"10.17554/j.issn.2224-3992.2020.09.975","DOIUrl":"https://doi.org/10.17554/j.issn.2224-3992.2020.09.975","url":null,"abstract":"As research on the interplay of nutrition and mental health evolves, “nutritional medicine” is attracting new enthusiasm from clinicians across a broad range of clinical subspecialties. In this review, we describe potential relevance of 6 nutrients in particular — Vitamin A, Vitamin C, Zinc, Magnesium, L-tryptophan, and Omega-3 fatty acids — on reducing or preventing the target symptoms of stress and aggression. Briefly: (1) Vitamin A may reduce the physical symptoms of stress, including inflammation, while (2) Vitamin C may reduce psychological distress and attenuate acute mammalian stress-response; stress may (3) increase the body’s demand for Mg and exacerbate Mg deficiency, while Mg deficiency itself may increase vulnerability under particular stressors; (4) Zinc deficiency appears to correlate with psychological adaptive potential; (5) Omega-3 fatty acids may mitigate aggression and anger for stressed mammalians. Tryptophan (6) depletion, finally, appears to correlate with increased aggression. Broadly speaking, as the literature evolves, there increasingly appears to be meaningful correlations between these nutrients and stress and aggression that justifies a call for further research.","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44005271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

COVID-19 Outbreak and IBD Patient: A Challenge COVID-19疫情和IBD患者:一个挑战

Journal of gastroenterology and hepatology research Pub Date : 2020-12-21 DOI: 10.17554/j.issn.2224-3992.2020.09.981

M. Maher, Hazem M Rizk

引用次数: 0

Prevention of PEG Tube Misplacement in the Transverse Colon: Method of Introducing a Gastrografin into the Stomach 预防横结肠内PEG管错位:胃内引入胃grafin的方法

Journal of gastroenterology and hepatology research Pub Date : 2020-10-21 DOI: 10.17554/j.issn.2224-3992.2020.09.968

H. Ono, H. Yokoyama, H. Yoshida, H. Fukushima, M. Kawakami, M. Okamura, T. Aoki, N. Asakage, K. Nagashima, Y. Danjo, H. Hayashi, H. Nishihara, Y. Shimizu, T. Shimamura, M. Kusano

{"title":"Prevention of PEG Tube Misplacement in the Transverse Colon: Method of Introducing a Gastrografin into the Stomach","authors":"H. Ono, H. Yokoyama, H. Yoshida, H. Fukushima, M. Kawakami, M. Okamura, T. Aoki, N. Asakage, K. Nagashima, Y. Danjo, H. Hayashi, H. Nishihara, Y. Shimizu, T. Shimamura, M. Kusano","doi":"10.17554/j.issn.2224-3992.2020.09.968","DOIUrl":"https://doi.org/10.17554/j.issn.2224-3992.2020.09.968","url":null,"abstract":"AIM: A colocutaneous fistula is a rare late complication of percutaneous endoscopic gastrostomy (PEG) feeding placement that occurs as a result of the interposition of the colon between the anterior abdominal and gastric walls. In the current study, we sought to retrospectively study the method of introducing the water-soluble contrast agent into the stomach by using a nasogastric tube before PEG feeding placement, with the intention to develop a method to prevent PEG-related colocutaneous fistula. MATERIALS AND METHODS: Between October 2003 and April 2020, 341 patients underwent PEG placement at Seiwa Memorial Hospital. Patients were divided into two groups: 232 patients in Group A were given water-soluble contrast agent and 109 patients in Group B were not. All patients underwent PEG using introducer method placement after gastropexy under fluoroscopy. RESULTS: In Group A, 139 (59.9%) patients received PEG with a water-soluble contrast agent placed into the transverse colon, 75 (32.3%) received PEG with gas in the colon, and 7 (3.0%) patients received surgical gastrostomy. In Group B, 38 (34.8%) patients received PEG with gas in the colon, 60 (55.1%) patients received PEG with finger palpation and transillumination, and 10 (9.2%) patients received surgical gastrostomy. Colocutaneous fistula was not observed in either group, but there was a significant difference in the frequency of surgical gastrostomy between Group A and B ( p = 0.0148). CONCLUSION: The use of water-soluble contrast agent in the stomach was safe, reliable, and cost effective for PEG tube placement, and is recommended to decrease surgical gastrostomy.","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"9 1","pages":"3320-3324"},"PeriodicalIF":0.0,"publicationDate":"2020-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47249627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thirty-Day Unplanned Readmission and Its Effect on 90-Day Mortality in Hepatocellular Carcinoma Patients Undergoing Partial Hepatectomy 肝部分切除术后30天非计划再切除及其对肝癌患者90天死亡率的影响

Journal of gastroenterology and hepatology research Pub Date : 2020-10-21 DOI: 10.17554/j.issn.2224-3992.2020.09.973

Yongyue Qi, T. LeVan, G. Haynatzki, C. Are, P. Farazi

{"title":"Thirty-Day Unplanned Readmission and Its Effect on 90-Day Mortality in Hepatocellular Carcinoma Patients Undergoing Partial Hepatectomy","authors":"Yongyue Qi, T. LeVan, G. Haynatzki, C. Are, P. Farazi","doi":"10.17554/j.issn.2224-3992.2020.09.973","DOIUrl":"https://doi.org/10.17554/j.issn.2224-3992.2020.09.973","url":null,"abstract":"Background : Despite advances of surgical techniques, hepatectomy continues to be potentially dangerous and is associated with postoperative mortality, morbidity and readmission. The objective of this study was to determine the effect of 30-day unplanned readmission on ‘conditional’ 90-day mortality among hepatocellular carcinoma (HCC) patients that underwent partial hepatectomy. Methods : National Cancer Database (NCDB) was queried from 2004 to 2012 for patients with hepatocellular carcinoma (HCC) who underwent partial hepatectomy. Thirty-day unplanned readmission rate, and associated risk factors, was determined for 7,696 patients. The association between 30-day unplanned readmission and conditional 90-day mortality was further addressed. Results : The 30-day unplanned readmission rate for patients with HCC that underwent partial hepatectomy was 5.2%. Risk factors associated with 30-day unplanned readmission were sex, race/ethnicity, Charlson-Deyo score, and annual hospital hepatectomy volume. An overall adjusted odds ratio of having conditional 90-day mortality was 2.325 times higher (95% CI 1.643 - 3.219) among patients with a history of 30-day unplanned readmission than those without. This association was dependent on age, sex, race/ethnicity, insurance status, alpha-fetoprotein (AFP), liver fibrosis, Charlson-Deyo comorbidity score and annual hospital hepatectomy volume. Conclusion : Efforts in patient care should be taken to reduce 30-day unplanned readmission after partial hepatectomy for patients with HCC to reduce conditional 90-day mortality.","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"9 1","pages":"3330-3339"},"PeriodicalIF":0.0,"publicationDate":"2020-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44412342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0