International journal of biotechnology for wellness industries最新文献

{"title":"Perah oil: a potential substitute for omega-3 oils and its chemical properties","authors":"N. Tan, B. M. Siddique, I. Muhamad, L. Salleh, N. Hassan","doi":"10.6000/1927-3037.2013.02.01.4","DOIUrl":"https://doi.org/10.6000/1927-3037.2013.02.01.4","url":null,"abstract":"Abstract: The perah seed oil is a potential source for high unsaturated and omega 3 oil. It can be an alternative choice for regular vegetable oil. The chemical and physical properties need to be investigated and evaluated for it to be used feasibly in the food industries and health care products. Modern day’s faster and sophisticated instruments and techniques are used to evaluate the physicochemical properties of edible or vegetable oils. This study includes FTIR spectroscopy GC-MS and GC to evaluate the chemical properties of it while colour was used to study the physical property. The peaks by FTIR were found at 3300-3000 cm -1 , 2960‐2850 cm -1 , 1760‐1670 cm -1 , 1650‐1580 cm -1 , and 1340‐1020 cm -1 . The GC-MS discover the potential beneficial compounds that available in extracted perah oil which are squalene, Vitamin E,and L.beta.-sitosterol. The GC data demonstrate about the free fatty acid profile which showed the high unsaturation in all oil samples extracted by different solvents. However, the colour measure for the visual suitable acceptability use for food or cosmetic application.","PeriodicalId":90181,"journal":{"name":"International journal of biotechnology for wellness industries","volume":"2 1","pages":"22-28"},"PeriodicalIF":0.0,"publicationDate":"2013-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71248370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MarA, SoxS and Rob of <i>Escherichia coli</i> - Global regulators of multidrug resistance, virulence and stress response.","authors":"Valérie Duval,&nbsp;Ida M Lister","doi":"10.6000/1927-3037.2013.02.03.2","DOIUrl":"https://doi.org/10.6000/1927-3037.2013.02.03.2","url":null,"abstract":"<p><p>Bacteria have a great capacity for adjusting their metabolism in response to environmental changes by linking extracellular stimuli to the regulation of genes by transcription factors. By working in a co-operative manner, transcription factors provide a rapid response to external threats, allowing the bacteria to survive. This review will focus on transcription factors MarA, SoxS and Rob in <i>Escherichia coli</i>, three members of the AraC family of proteins. These homologous proteins exemplify the ability to respond to multiple threats such as oxidative stress, drugs and toxic compounds, acidic pH, and host antimicrobial peptides. MarA, SoxS and Rob recognize similar DNA sequences in the promoter region of more than 40 regulatory target genes. As their regulons overlap, a finely tuned adaptive response allows <i>E. coli</i> to survive in the presence of different assaults in a co-ordinated manner. These regulators are well conserved amongst <i>Enterobacteriaceae</i> and due to their broad involvement in bacterial adaptation in the host, have recently been explored as targets to develop new anti-virulence agents. The regulators are also being examined for their roles in novel technologies such as biofuel production.</p>","PeriodicalId":90181,"journal":{"name":"International journal of biotechnology for wellness industries","volume":"2 3","pages":"101-124"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.6000/1927-3037.2013.02.03.2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32367206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biosorption of Cr(III), Fe(II), Cu(II), Zn(II) Ions from Liquid Laboratory Chemical Waste by Pleurotus ostreatus","authors":"Muhammad Arbanah, M. Najwa, K. Halim","doi":"10.6000/1927-3037/2012.01.03.01","DOIUrl":"https://doi.org/10.6000/1927-3037/2012.01.03.01","url":null,"abstract":"Heavy metals present in the liquid laboratory chemical waste should be removed due to their hazards to human health and environment. Among them, Cr(III), Cu(II), Fe(II), Zn(II) are usually exist. The conventional treatments in the heavy metals removal have several limitations which encourage researchers to search for alternative treatment methods. One of possible method in the removal of heavy metal ion is through biosorption. Therefore, the present study aims to evaluate the effectiveness of white root fungus (mushroom) viz., P.ostreatus to absorb Cr(III), Cu(II), Fe(II), Zn(II) from liquid laboratory chemical waste. It was found that the best operating treatment process was at pH above 4.0. The highest biosorption efficiency for Fe(II) and Cu(II) was shown at pH 6 with 80.52% and 45.20% while Zn(II) at pH 4 (5.04%) and Cr(III) at pH 5 with 21.14% at agitation speed of 150 rpm and temperature of 25°C. Throughout the research, the percentage of removal was found to be increased with the increasing of contact time between P.ostreatus and liquid laboratory chemical waste. Almost 17.02% of Cr( III ), 55.35% of Fe(II), 15.34% of Cu(II) and 13.34% of Zn(II) were removed from chemical waste. This validates that P.ostreatus is potential as biosorbent for liquid laboratory chemical waste treatment.","PeriodicalId":90181,"journal":{"name":"International journal of biotechnology for wellness industries","volume":"1 1","pages":"152-162"},"PeriodicalIF":0.0,"publicationDate":"2012-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71249755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reversing Early Stage Prostate Cancer in a Hypertensive Patient: A Case Study on Nutritional cum Phyto-therapy","authors":"S. Yap","doi":"10.6000/1927-3037/2012.01.03.06","DOIUrl":"https://doi.org/10.6000/1927-3037/2012.01.03.06","url":null,"abstract":"While prostate cancer is the most common male malignancy in the West, it is ranked as the number two cancer death for non-smokers in many developing countries. This case study demonstrates how an early stage prostate cancer might be treated by a comprehensive and evidence-based nutritional cum phytotherapy if patient is given the option of using it. According to the ANMP ( www.anmp.org.my ), a nutritional therapy is used to treat, control, or prevent chronic disorders by impacting on the hormonal, neurological, and immune functions of the patient. It may take a decade or longer to develop a malignancy. Three quarter of prostate cancer occurs in men over fifty five years when they go through andropause, which is evidenced partly by elevation in their oestrogen levels. However, being overweight or obese may trigger early progression of prostate cancer in men.","PeriodicalId":90181,"journal":{"name":"International journal of biotechnology for wellness industries","volume":"1 1","pages":"199-209"},"PeriodicalIF":0.0,"publicationDate":"2012-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71249954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paraconiothyrium sp. P83F4/1: antioxidant and antiproliferative activities of endophytic fungus associated with Rheedia brasiliensis plant","authors":"Patrícia Lunardelli Negreiros de Carvalho, Priscilla Oliveira Amaral, Ana Lúcia Tasca Gois Ruiz, S. M. Alencar, L. Pfenning, J. Carvalho, P. Rosalen, M. Ikegaki","doi":"10.6000/1927-3037/2012.01.03.03","DOIUrl":"https://doi.org/10.6000/1927-3037/2012.01.03.03","url":null,"abstract":"The endophyte Paraconiothyrium sp. P83F4/1 was isolated from leaves of the Rheedia brasiliensis medicinal plant from a bioprospecting study. This is the first report of isolation of Paraconiothyrium in leaves of R. brasiliensis and the fermentation product obtained with this fungus in ethyl acetate was evaluated for their potential bioactive through antioxidant assay by DPPH (radical 1,1-diphenyl-2-picrylhydrazyl) method and antiproliferative assays in human tumoral cells using the sulphorhodamine B (SRB) technique for evaluating the cellular growth. The antioxidant assay, tested at 90 mg/mL, the fungal extract showed scavenging capacity of 58.92 %, being significant (p<0.05) compared the standard commercial butyl hydroxy toluene: 39.52 %. In the antiproliferative assay, the extract was selective on human keratinocyte cells (HaCat) with GI 50 0.95 mg/mL, whose mean log GI 50 = - 0.02, according to National Cancer Institute (NCI-USA) criteria, it makes a powerful extract. Cells HaCat are involved directly in diseases such as psoriasis. These results indicate the antioxidant and antiproliferative potentials of the crude extract of fermentation of the endophytic fungus Paraconiothyrium sp. P83F4/1 isolated from the leaves of R. brasiliensis.","PeriodicalId":90181,"journal":{"name":"International journal of biotechnology for wellness industries","volume":"1 1","pages":"172-176"},"PeriodicalIF":0.0,"publicationDate":"2012-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71249818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Photo-Protective Activity of Crataegus monogyna Extract Proved by Complementary Mechanisms of Skin Inflammation, Damage of Extracellular Matrix, Cellular Survival and Proliferation Disorders","authors":"B. Dumitriu, L. Olariu, D. Ene, L. Zglimbea, N. Roșoiu","doi":"10.6000/1927-3037/2012.01.03.04","DOIUrl":"https://doi.org/10.6000/1927-3037/2012.01.03.04","url":null,"abstract":"The skin photo-ageing and photo-carcinogenesis are based on cellular mechanisms triggered by UV-radiation, starting with oxidative stress and inflammation, activation of matrix-metalloproteinase (MMP) that increase the structural protein degradation, ending with DNA damage and apoptosis induction. In order to claim the photo-protective activity of an ingredient it’s important to explore the main pathways involved in this complex process, highlighting its target action. Our studies are based on a cellular screening of UV-A and UV-B irradiated keratinocytes (HaCat cell line), focusing on the apoptosis induction, cell cycle sequentiation, metalloproteinase’s expression, pro-inflammatory cytokines release and IL1α as sensitization molecule, as well as the antioxidant capacity of the extract, and acting on catalase and superoxide-dismutase activity. The investigation techniques are flow cytometry (cellular parameters fluorescent staining and beads-based assay for soluble protein detection), zymography and enzymatic activity tests. The Crataegus monogyna extract, with a rich content of pro-antocians, flavones and polyphenolcarboxylic acids, show a UV-A cellular protection and dose dependent inhibition of inflammatory cytokines and MMP2 and 9 after both UV-A and UV-B irradiation. All these effects are sustained by a cumulative antioxidant capacity at enzymatic and intracellular oxygen radical level. These findings recommend the phyto-complex for the prevention or therapy of UV-photo damages.","PeriodicalId":90181,"journal":{"name":"International journal of biotechnology for wellness industries","volume":"1 1","pages":"177-188"},"PeriodicalIF":0.0,"publicationDate":"2012-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71249842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probiotics for everyone! The novel immunobiotic lactobacillus rhamnosus CRL1505 and the beginning of social probiotic programs in Argentina","authors":"J. Villena, S. Salva, M. Núñez, J. Corzo, René Tolaba, Julio Faedda, G. Font, S. Alvarez","doi":"10.6000/1927-3037/2012.01.03.05","DOIUrl":"https://doi.org/10.6000/1927-3037/2012.01.03.05","url":null,"abstract":"Lactobacillus rhamnosus CRL1505 (Lr1505) stimulates immune responses in the gut and in the respiratory tract and improves resistance against Salmonella typhimurium and Streptococcus pneumoniae infections in immunocompetent and immunocompromised mice. Considering that respiratory infectious diseases continue to be a major cause of death among preschool children in developing countries, the aim of the present study was to evaluate the effect of Lr1505 on the health of children. A randomized-controlled double-blind clinical trial in 298 healthy children (2-5 years old), attending daycare centers was performed. Yogurt containing Lr1505 was administered to children for 6 months (five times a week). Results were statistically compared with those of children from the same community that received a placebo yogurt (without probiotic). Administration of Lr1505 to young children reduced the incidence of infections: 66% of children in the placebo group presented symptoms of infection while only 34% of cases were detected in the Lr1505 group. Significant differences ( P <0.05) were detected in the incidence of intestinal infections, upper respiratory tract infections and angina when placebo and Lr1505 groups were compared. Children fed Lr1505 experienced fewer fevers and needed fewer antibiotics than those receiving the placebo. The protective effect of Lr1505 was associated with increased levels of mucosal IgA antibodies. Lr1505 is a promising resource for the development of prevention strategies against mucosal infections that could be effective tools for medical application. This new probiotic strain has been included into official Nutritional Programs in Argentina and it is given to more than 200 thousand children. This project has encouraged local milk production, thanks to the constant demand of probiotic yogurt containing L. rhamnosus CRL1505 by provincial governments, while incorporating innovation to small and medium enterprises.","PeriodicalId":90181,"journal":{"name":"International journal of biotechnology for wellness industries","volume":"1 1","pages":"189-198"},"PeriodicalIF":0.0,"publicationDate":"2012-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71249879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rosemary and Sage Outperformed Six other Culinary Herbs in Antioxidant and Antibacterial PropertiesRosemary and Sage Outperformed Six other Culinary Herbs in Antioxidant and Antibacterial Properties","authors":"E. Chan, L. Kong, K. Y. Yee, W. Chua, T. Loo","doi":"10.6000/1927-3037/2012.01.02.06","DOIUrl":"https://doi.org/10.6000/1927-3037/2012.01.02.06","url":null,"abstract":"The antioxidant and antibacterial properties of Labiatae culinary herbs are well documented but the effects of different drying methods are poorly studied. In this study, the antioxidant and antibacterial properties of fresh and oven-dried herbs of oregano, marjoram, rosemary, sage, basil, thyme, peppermint and spearmint were compared with available commercial herbs. Antioxidant properties of total phenolic content, total flavonoid content, caffeoylquinic acid content, free radical scavenging activity, ferric reducing power and ferrous ion chelating ability were assessed using the Folin-Ciocalteu, aluminium chloride, molybdate, DPPH radical scavenging, potassium ferricyanide and ferrozine assays, respectively. Antibacterial properties were assessed using the disc diffusion assay based on mean diameter of inhibitory zone and minimum inhibitory dose. The two drying treatments were oven drying at 50 o C (OD) and microwave pre-treatment followed by oven drying at 50 o C (MOD). Fresh rosemary and dried oregano had the strongest antioxidant properties. For most herbs, oven drying resulted in loss of  antioxidant values compared to fresh herbs with the exception of oregano. Values of OD and MOD oregano, spearmint, thyme, peppermint and basil were higher than commercial samples, while those of rosemary were lower. Of the six commercial herbs, rosemary had the highest values, followed by oregano, spearmint, thyme, peppermint and basil. Rosemary, sage, peppermint and spearmint inhibited the growth of all three Gram-positive bacteria of Bacillus cereus , Micrococcus luteus and Staphylococcus aureus . Rosemary and sage had stronger antibacterial properties than green and black teas of Camellia sinensis . When used in combination, rosemary and sage can have enhanced antioxidant and antibacterial effects, which are desirable in developing nutraceutical products, and in controlling rancidity and bacterial growth in food.","PeriodicalId":90181,"journal":{"name":"International journal of biotechnology for wellness industries","volume":"1 1","pages":"142-151"},"PeriodicalIF":0.0,"publicationDate":"2012-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71250167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Effects of Several Parameters on the Growth of Chlorella vulgaris Using Taguchi's Experimental Approach","authors":"R. Barghbani, K. Rezaei, A. Javanshir","doi":"10.6000/1927-3037/2012.01.02.04","DOIUrl":"https://doi.org/10.6000/1927-3037/2012.01.02.04","url":null,"abstract":"Algae are part of photosynthetic organisms that play an important role in the aquatics nutrition. Like plants, algae need water, light and CO 2 to grow. Using Taguchi’s experimental approach (5 factors in four levels with 16 runs), effects of several parameters (NaCl, sodium bicarbonate and iron concentrations as well as light and temperature) on the growth of Chlorella vulgaris was studied. Increasing the concentrations of NaCl and sodium bicarbonate resulted in corresponding decreases in the growth of C. vulgaris . Media with 30.0g l -1 NaCl did not indicate any algal growth. Also, with 9.0 g l -1 sodium bicarbonate, biomass production was decreased. Chlorella vulgaris showed different growing behaviors at the various concentrations of iron (Fe +2 ) and at the different temperatures of this study . Maximum biomass production (approximately 3.56 g dry matter) was obtained at the 0.0 g l -1 sodium bicarbonate, 10.0g l -1 NaCl, 18.0 µmol l -1 iron and at 30±2 °C. Yellow and blue lights increased the algal growth. Analysis of variance showed that salinity (i.e., the NaCl concentration) had the highest impact on the biomass production.","PeriodicalId":90181,"journal":{"name":"International journal of biotechnology for wellness industries","volume":"12 1","pages":"128-133"},"PeriodicalIF":0.0,"publicationDate":"2012-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71250211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dilute Solution Viscometry Studies on a Therapeutic Mixture of Non-digestible Carbohydrates","authors":"S. Harding, F. Almutairi, G. Adams, G. Morris, C. J. Lawson, R. Gahler, S. Wood, Clifton Boulevard, E. Gate","doi":"10.6000/1927-3037/2012.01.02.01","DOIUrl":"https://doi.org/10.6000/1927-3037/2012.01.02.01","url":null,"abstract":"Recent work has shown the beneficial effects of a proprietary mixture of three non-digestible carbohydrates: konjac glucomannan, xanthan and alginate and these effects have been linked with a synergistic interaction observable with analytical ultracentrifugation, rheological and NMR measurements. These observations have been supported by fundamental dilute solution viscosity studies. Preparations of konjac glucomannan, xanthan and alginate have been checked with regards their molecular integrity (molar mass distribution) using a newly established method based on the analytical ultracentrifuge. The intrinsic viscosity behaviour for each of the individual polysaccharides were estimated at low ionic strength I (10 -3 M) and found to be (2090±120) ml/g, (4430±340) ml/g and (3460±330) ml/g for konjac glucomannan, xanthan and alginate respectively and at (10 -1 M) (2350±200) ml/g, (3370±310) ml/g and (1210±50) ml/g respectively. The intrinsic viscosity (η) was then determined for a proprietary mixture of the three (known as \"PGX®\") at both ionic strengths and compared with the predicted values for a non-interacting mixture. In I=10 -3 M solvent a significant difference was observed (3090+250) ml/g compared with the predicted value (2350+300) ml/g, although at higher ionic strength the interaction appears to have gone: (η) = (1990+250) ml/g compared with the predicted value of (2180+300) ml/g. This appears to reinforce the earlier observations that in PGX® there is a synergistic interaction which is ionic strength sensitive.","PeriodicalId":90181,"journal":{"name":"International journal of biotechnology for wellness industries","volume":"1 1","pages":"107-114"},"PeriodicalIF":0.0,"publicationDate":"2012-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71249983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}