{"title":"MOBILE COMMUNICATIONS FOR USING IN TELEMEDICINE","authors":"M. Saeedi, M. Torabi, Sakineh Hamidi, H. Ranji","doi":"10.3844/AMJSP.2014.8.12","DOIUrl":"https://doi.org/10.3844/AMJSP.2014.8.12","url":null,"abstract":"Telemedicine the use of telecommunication and information technologies in order to provide clinical health care at a distance helps eliminate distance barriers and can improve access to medical services that would often not be consistently available in distant rural communities. It is also used to save lives in critical care and emergency situations. Although there were distant precursors to telemedicine, it is essentially a product of 20th century telecommunication and information technologies. These technologies permit communications between patient and medical staff with both convenience and fidelity, as well as the transmission of medical, imaging and health informatics data from one site to another. Early forms of telemedicine achieved with telephone and radio have been supplemented with video telephony, advanced diagnostic methods supported by distributed client/server applications and additionally with telemedical devices to support in-home care. There is a growing trend in the health domain to incorporate Smartphones and other wireless technologies to provide more efficient, cost effective and higher quality healthcare. With newer more sophisticated mobile devices for example, Smartphones this is an escalating practice. To date the use of mobile phone technology in the healthcare domain (mHealth) has been limited to uses such as disseminating information. However, mHealth is beginning to include software and data applications based on mobile devices and technologies. This movement is largely due to the advent of newer technologies associated with Smartphones. Some Smartphones can now be considered to be intelligent sensors with sensing capabilities such as Global Positioning System (GPS) location, proximity and accelerometers. This study examines the use of such technology in providing seamless mobile communications for telemedicine.","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"5 1","pages":"8-12"},"PeriodicalIF":0.0,"publicationDate":"2014-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2014.8.12","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70192855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christos G. Paganias, George Tsakotos, Stephanos D. Koutsostathis, G. Macheras
{"title":"THE PROCESS OF POROUS TANTALUM IMPLANTS OSSEOUS INTEGRATION A REVIEW","authors":"Christos G. Paganias, George Tsakotos, Stephanos D. Koutsostathis, G. Macheras","doi":"10.3844/AMJSP.2014.63.72","DOIUrl":"https://doi.org/10.3844/AMJSP.2014.63.72","url":null,"abstract":"Porous tantalum is a biomaterial that was recently introduced in orthopaedics in order to overcome problems of the past related to implant loosening. Its use has led to very good results, especially in difficult cases where severe bone defect is present, as it is found to have osteoconductive and possibly, osteoinductive properties. So, it is of great inter est to shed light to the mechanisms through which t his material leads to new bone formation after being im planted. For this reason, a review of the current literature was undertook. Porous tantalum is, biolo gically, relatively inert, meaning that its bonding capacity to the bone is restricted. In order to overcome this o bstacle, it undergoes thermal processing in alkalin e environment. This process leads to extensive hydroxyapatite form ation on its surface and thus, to better integratio n of porous tantalum implants. Apart from this, new bone tissue formation occurs inside the pores of porous tantal um after its implantation and this new bone retains the characte ristics of normal bone, i.e., bone remodeling and H aversian systems formation. This finding is enhanced by the observation that porous tantalum is an appropriate substrate for osteoblast adherence, proliferation and differe ntiation. Furthermore, the finding that osteoblasts derived from old women (>60 years old) and cultivated on porous tantalum may grow faster than osteoblasts taken fro m younger women (<45 years old) and cultivated on other substrates, can partially explain porous tantalu m good performance in cases of patients with severe bone d efects. In conclusion, porous tantalum chemical and mechanical properties are those that, probably, def ine the already noticed good performance of this ma terial. However, further research is needed to totally clar ify the mechanisms through which they contribute to that.","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"5 1","pages":"63-72"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2014.63.72","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70192846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Reis, M. Orsini, M. Leite, M. Freitas, J. Souza, V. Bastos, C. Bruno, Mariane Doelinger Barbosam, C. O. Vilaça, A. Oliveira
{"title":"AMYOTROPHIC LATERAL SCLEROSIS: HOW TO UNDERSTAND SUCH DIVERSE AND SO ENTANGLED PHYSIOPATHOLOGY?","authors":"C. Reis, M. Orsini, M. Leite, M. Freitas, J. Souza, V. Bastos, C. Bruno, Mariane Doelinger Barbosam, C. O. Vilaça, A. Oliveira","doi":"10.3844/AMJSP.2014.37.38","DOIUrl":"https://doi.org/10.3844/AMJSP.2014.37.38","url":null,"abstract":"","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"5 1","pages":"37-38"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2014.37.38","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70192694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"GENOTYPIC IDENTIFICATION OF CANDIDA SPP. ISOLATED FROM ONYCHOCANDIDIASIS PATIENTS BY PHENOTYPIC METHODS, PCR AND RAPD-PCR","authors":"Z. Imran, H. AL-Ghalibi","doi":"10.3844/AMJSP.2014.1.7","DOIUrl":"https://doi.org/10.3844/AMJSP.2014.1.7","url":null,"abstract":"Candidal Onychomycosis (COM) is a common nail disease which plays as sources pathogenic reservoir giving a rise to repeated candidiasis infections. This study aimed to evaluate PCR assays and phenotypic tests for identification of yeasts isolated from COM patients. The study included 100 clinically suspected patients of COM attending the main hospital and clinics in Al-Dewania province in the middle of Iraq during September 2011 to April 2012. One hundred yeast isolates were identified morphologically by CHROMagar medium. DNA was extracted from 14 representative’s isolates for accurate identification by PCR and fingerprinted by RAPD-PCR. Phenotypic examination of 100 yeasts isolates on CHROMagar revealed that these isolates were classified into 7 different species belonged to Candida form genus, PCR assay revealed that primer pair ITS1 and ITS4 was successfully amplified ITS1-5.8S-ITS2 rDNA region for 14 isolates of Candida spp. yielding a unique PCR products approximately 510-650bp in length. The results of RAPD-PCR assay showed that both primers (TAGGATCAGA and AGGTCACTGA) were genotyped 14 isolates of Candida into seven main genotypes; three of these genotypes had highly percentage of homologous (80-100%) among related isolates were studied in each Candida isolates, while the others four genotypes had 10-50% homologous. This study concluded that for accurate and prices identification must used PCR and fingerprinted by RAPD-PCR assays, the results of CHROMagar were correlated with gene expression for each Candida isolates, while the results of RAPD PCR assay were correlated with degrees similarity and difference of genotypes for Candida isolates under interest.","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"5 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2014.1.7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70192617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Sureshkumar, R. Gopalakrishnan, Abdulghafur, Venkatsubramanian Ramasubramainain
{"title":"Vancomycin Mic Creep Among Methicillin-Resistant Staphylococcus aureus: A Report","authors":"D. Sureshkumar, R. Gopalakrishnan, Abdulghafur, Venkatsubramanian Ramasubramainain","doi":"10.3844/AMJSP.2013.197.200","DOIUrl":"https://doi.org/10.3844/AMJSP.2013.197.200","url":null,"abstract":"The objective of the study was to analyze the vancomycin MIC distribution against bloodstream MRSA isolates for a period of 1 year in India. This retrospective study analyzed 71 blood stream MRSA strains isolated at a tertiary care hospital in India between January 2008 and December 2008. The vancomycin MIC was determined by broth microdilution method. Only one isolate per patient was analyzed. The range of vanocmycin MIC for the 71 isolates in this study was varied between 0.25-3 µg mL-1. Only 29 isolates had MIC less than 1 µg mL-1 and 17 isolates MIC were more than 2 µg mL-1. In this study the phenomenon of vancomycin MIC creep was noticed in more than 75% of MRSA bloodstream isolates. We suggest further in vivo studies to determine the clinical significance of this MIC creep.","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"4 1","pages":"197-200"},"PeriodicalIF":0.0,"publicationDate":"2013-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2013.197.200","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70192411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Taherianfard, B. Geramizadeh, M. Banihashemi, Afsaneh Asgari Taiee, R. Ensannejad
{"title":"EFFECT OF BISPHENOL A ON PASSIVE AVOIDANCE PERFORMANCE IN MALE RATS","authors":"M. Taherianfard, B. Geramizadeh, M. Banihashemi, Afsaneh Asgari Taiee, R. Ensannejad","doi":"10.3844/AMJSP.2013.190.196","DOIUrl":"https://doi.org/10.3844/AMJSP.2013.190.196","url":null,"abstract":"Bisphenol A (BPA) is used to manufacture polycarbonate plasti c products in resins lining metal cans, in dental sealants and in blends with other types of plastic products. In sharp cont rast, there are many published studies that BPA has a wide range of significant adverse effects including structural and neurochemical changes throughout the brain associated with behavioral changes, such as hyperactivity, learning deficits and increased aggression in both males and females. So the aim of the present study was to investigate effect of BPA on learning and memory in passive avoidance learning model. Thirty six male Sprague Dawley rats weighing 180-260 g were used. The animals were divided into six groups: 1- control group (without any treatment) 2-sham group (received sesame oil the same volume as experimental, n = 6 ); 3-5 experimental (received BPA 5, 50, 100 and 150 mg kg -1 day, n = 24). BPA was administrated by oral intake by gavage for 15 days. Learning and memory were performed by shuttle-box. Data was analyzed by Kruskal-Wallis nonparametric test. The level of sig nificance was considered P<0.05. Our data showed that BPA does not have a significant difference in time spent in light in doses of 5, 50 mg kg -1 day in learning and memory. BPA with dose of 100 and 150 mg kg -1 day showed a significant decrease in time spent in light relative to the control and sham in learning and memory. According to our results, BPA impaired learning and avoidance memory with high doses in the passive avoidance learning task.","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"4 1","pages":"190-196"},"PeriodicalIF":0.0,"publicationDate":"2013-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2013.190.196","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70192353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Sánchez-Aguilar, L. Ibarra-Lara, B. Zamora-López, A. Sánchez-Mendoza, A. Zamorano-Carrillo
{"title":"DETECTING PATTERNS IN 5' UNTRANSLATED REGIONS OF GENES INVOLVED IN THE REGULATION OF BLOOD PRESSURE AND OXIDATIVE STRESS","authors":"M. Sánchez-Aguilar, L. Ibarra-Lara, B. Zamora-López, A. Sánchez-Mendoza, A. Zamorano-Carrillo","doi":"10.3844/AMJSP.2013.184.189","DOIUrl":"https://doi.org/10.3844/AMJSP.2013.184.189","url":null,"abstract":"Hypertension is a chronic physical condition with multifactorial causes. Although genetic factors have been associated to this pathological condition, characterization of the sequence patterns in the regulatory sites, for example, in 3’ or 5’ Untranslated Regions (UTR), remains to be explored. In particular, the 5’ UTR of genes associated with the regulation of blood pressure and oxidative stress are analyzed in this article. To gain insight into how certain DNA motifs are involved with high blood pressure, we decided to perform a study with sequences from genes reported as regulators of blood pressure and oxidative stress. 5’ UTR gene sequences were submitted to patterns recognition by the Multiple Em for Motif Elicitation (MEME) software. Afterward, the motifs obtained were searched for in the Transcription Element Search System (TESS) and Consite platforms, in order to identify the submitted sequence as element response of some transcription factor described previously. Three different motifs in each group of vasorelaxing-and vasocontractile-related gene sequences were detected. In the vasorelaxing group, motif lengths were 39 to 50 nucleotides and were located from -361 to -167 bp before the Open Reading Frame (ORF). In turn, motifs in vasocontractile group sequences were located from -619 to -570 nucleotides, with a length of from 18 to 40 nucleotides. Regarding the nucleic acid content in the motifs found, adenine was more prevalent in vasorelaxing-related sequences with 45% of the average frequency, whereas guanine on those vasocontractile-related sequences with 38%. Distinct motif sequences and variations of nucleotide content in the promoter region of vasorelaxing and vasocontractile-activity related genes were detected. These motifs of each group of genes, with a putative antagonistic role between them, might be a differential cis-regulatory elements of transcriptional machinery.","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"4 1","pages":"184-189"},"PeriodicalIF":0.0,"publicationDate":"2013-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2013.184.189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70192298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. A. M. Q. Carreira, F. Pena, M. Rachid, Leandro D. Tellerman, Fabiana A Montaleone, Daniel C.A. Goncalves, Maria Eduarda D.C. Lobo
{"title":"Velocity of Heart Rate Recovery in Post-Exercise Under Different Protocols of Active Recovery","authors":"M. A. M. Q. Carreira, F. Pena, M. Rachid, Leandro D. Tellerman, Fabiana A Montaleone, Daniel C.A. Goncalves, Maria Eduarda D.C. Lobo","doi":"10.3844/AMJSP.2013.179.183","DOIUrl":"https://doi.org/10.3844/AMJSP.2013.179.183","url":null,"abstract":"Abnormalities in the modulation of parasympathetic activity have been identified as a possible pathophysiological link with the association between decreases in heart rate recovery after exercise test. Hypothesis: To investigate if the application of different protocols of active recovery promotes difference in reducing Heart Rate (HR) in Post-Exercise (PE). This was a prospective, randomized trial of patients undergoing Exercise Testing (ET) and applied to two different protocols of active recovery. They were divided into G1 with recovery of 1.5 mph/2.5% and G2 40% of the speed and slope of the peak in the PE. Variables were evaluated pre-test and intrinsic to the TE. We compared the recovery of FC 1 and 2 min in the PE. Statistical analysis used the chi-square test, Student’s t test and considered p","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"4 1","pages":"179-183"},"PeriodicalIF":0.0,"publicationDate":"2013-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2013.179.183","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70192284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Alzheimer’s Disease Prognosis is Captured by a Down-Upsized Incidence Poisson Distribution","authors":"R. Shanmugam","doi":"10.3844/AMJSP.2013.150.159","DOIUrl":"https://doi.org/10.3844/AMJSP.2013.150.159","url":null,"abstract":"Alzeimer disease is a daunting nightmare to both the medical and families of the patients. Tireless efforts are made by the medical researchers to treat Alzheimer’s patients. The Alzhiemer patients’ data provides clues about its prognosis and they can be identifies when the data are analyzed and understood correctly. The data analysis is a first step in the path to breakthrough treatment. Towards this aim, this article introduces a new statistical distribution and calls it Down-Upsized Incidence Poisson Distribution (DUIPD). The properties of DUIPD are obtained and illustrated to interpret the patterns in the prognosis of two group of Alzheimer’s patients. In one group, the patients received a doseage of lecithin and other in the control group received placebo drug.","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"4 1","pages":"150-159"},"PeriodicalIF":0.0,"publicationDate":"2013-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2013.150.159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70192655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"U.S. MALPRACTICE IN INTERNAL MEDICINE: CLOSED CLAIM CASES AS TOOLS FOR IDENTIFICATION, TEACHING AND PREVENTION","authors":"Kimberly Ku, T. Vettese, D. Levine","doi":"10.3844/AMJSP.2013.168.178","DOIUrl":"https://doi.org/10.3844/AMJSP.2013.168.178","url":null,"abstract":"Medical malpractice litigation as a system in the U .S. serves multiple goals, including the promotion of safer medicine and the compensation of wrongfully i njured patients. However, these aims are often at o dds with systems-oriented strategies needed to promote patient safety. Additionally, there is widespread d oubt of the actual fairness and efficiency of malpractic e litigation. Regardless of the details surrounding major tort reform, to prevent malpractice claims physicia ns need to practice greater awareness of the eviden cebased factors that place them at higher risk for a malpractice claim. Closed claims can be used as pos itive teaching tools that allow physicians to recognize f or themselves important preventive strategies in th e area of litigation. Internal medicine may not traditiona lly be thought of as a comparatively high-risk spec ialty field. In reality, however, an analysis of physicia ns facing a malpractice claim annually across all s pecialties shows that the field of internal medicine achieved greater proportions compared to specialty fields th at are more often times considered higher-risk, such as em ergency medicine and anesthesiology. This article a ims to help the internal medicine physician in (1) anal yzing the most frequent clinical events that have l ed to malpractice claims by using a few showcase examples and (2) introducing how these examples of closed claim cases can serve as a learning resource to red uce medical errors that most commonly lead to litig ation and thus harms to both patient and provider.","PeriodicalId":89887,"journal":{"name":"American medical journal","volume":"4 1","pages":"168-178"},"PeriodicalIF":0.0,"publicationDate":"2013-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3844/AMJSP.2013.168.178","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70192226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}