Kevin G. Byrnes, Cameron Alexander, Mariam Lami, Marie Edison, Aqua Asif, Alexander Ng, Quentin Mak, Bing Jie Chow, Mathew Smith, Kevin Keane, Kevin Gallagher, Arjun S. Nathan, Sinan Khadhouri, Nikita R. Bhatt, Veeru Kasivisvanathan
{"title":"The LANDMARK project: providing summaries of key papers that have shaped urological practice","authors":"Kevin G. Byrnes, Cameron Alexander, Mariam Lami, Marie Edison, Aqua Asif, Alexander Ng, Quentin Mak, Bing Jie Chow, Mathew Smith, Kevin Keane, Kevin Gallagher, Arjun S. Nathan, Sinan Khadhouri, Nikita R. Bhatt, Veeru Kasivisvanathan","doi":"10.1111/bju.16548","DOIUrl":"10.1111/bju.16548","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"134 6","pages":"919-921"},"PeriodicalIF":3.7,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bju.16548","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patrick Gordon, Daryl Thompson, Oneel Patel, Ronald Ma, Damien Bolton, Joseph Ischia
{"title":"Ureteric stenting outside of the operation theatre: challenges and opportunities.","authors":"Patrick Gordon, Daryl Thompson, Oneel Patel, Ronald Ma, Damien Bolton, Joseph Ischia","doi":"10.1111/bju.16533","DOIUrl":"https://doi.org/10.1111/bju.16533","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the safety, efficacy, tolerability, and cost-effectiveness of bedside or office-based ureteric stent insertion.</p><p><strong>Methods: </strong>Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Protocols (PRISMA-P) and A MeaSurement Tool to Assess systematic Reviews (AMSTAR) 2 guidelines, we searched PubMed/the Medical Literature Analysis and Retrieval System Online (MEDLINE), the Excerpta Medica dataBASE (EMBASE), Google Scholar, Cochrane Central Register of Controlled Trials (CENTRAL), and Dimensions for English-language studies from 1978 to April 2023. Inclusion criteria focused on primary ureteric stent placements outside of the operating theatre (OT).</p><p><strong>Results: </strong>A total of 15 studies involving 2072 stents were included. Success rates for correctly positioned stents in bedside or office-based insertions ranged from 60% to 95.8%, with most studies reporting ≥80% success rates. Common failure reasons included impacted stones and difficulty identifying the ureteric orifice. Pain and tolerability were assessed using various methods, with validated tools indicating moderate pain levels, but most patients would undergo the procedure again under local anaesthesia. Complication rates were generally low, with minor complications such as haematuria or postoperative fever being the most common. Procedural costs were significantly lower in non-OT settings, with estimates indicating savings of up to four-fold.</p><p><strong>Conclusion: </strong>Bedside or office-based ureteric stent insertion is a viable alternative to OT procedures, offering high success rates, manageable pain levels, low complication rates, and substantial cost savings. This approach is particularly advantageous in settings with limited OT access, highlighting its potential for broader adoption in urological practice. Future research should focus on standardising pain assessment methods and randomised studies.</p>","PeriodicalId":8985,"journal":{"name":"BJU International","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to letter 'Bladder-centric benign prostatic hyperplasia management post-laser enucleation of the prostate'.","authors":"Cristina Cano Garcia, Andreas Becker","doi":"10.1111/bju.16542","DOIUrl":"https://doi.org/10.1111/bju.16542","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alessandro Izzo, Gianluca Spena, Giovanni Grimaldi, Giuseppe Quarto, Luigi Castaldo, Raffaele Muscariello, Dario Franzese, Francesco Passaro, Riccardo Autorino, Antonio Tufano, Sisto Perdonà
{"title":"Single-port robot-assisted nephroureterectomy via a supine anterior approach: step-by-step technique.","authors":"Alessandro Izzo, Gianluca Spena, Giovanni Grimaldi, Giuseppe Quarto, Luigi Castaldo, Raffaele Muscariello, Dario Franzese, Francesco Passaro, Riccardo Autorino, Antonio Tufano, Sisto Perdonà","doi":"10.1111/bju.16537","DOIUrl":"https://doi.org/10.1111/bju.16537","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The ‘balls’ of an ideal man?","authors":"Farrokh Habibzadeh","doi":"10.1111/bju.16538","DOIUrl":"10.1111/bju.16538","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"134 6","pages":"918-919"},"PeriodicalIF":3.7,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142370919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leilei Xia, J. Everett Knudsen, Daniel S. Roberson, Erika L. Wood, Anosh Dadabhoy, Sofia Romano, Thomas J. Guzzo, Trinity J. Bivalacqua, Siamak Daneshmand
{"title":"Residual cancer at radical cystectomy with or without neoadjuvant chemotherapy: a pathological stage‐matched comparison","authors":"Leilei Xia, J. Everett Knudsen, Daniel S. Roberson, Erika L. Wood, Anosh Dadabhoy, Sofia Romano, Thomas J. Guzzo, Trinity J. Bivalacqua, Siamak Daneshmand","doi":"10.1111/bju.16529","DOIUrl":"https://doi.org/10.1111/bju.16529","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"23 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samantha Conroy,Ibrahim Jubber,Aidan P Noon,Derek J Rosario,Jon Griffin,Susan Morgan,Rachel Hubbard,Steve Kennish,Stephen Mitchell,Suresh Venugopal,Kate Linton,Ramanan Rajasundaram,Syed A Hussain,James W F Catto
{"title":"Real-word outcomes for high-risk non-muscle-invasive bladder cancer: screened patients for the BRAVO trial.","authors":"Samantha Conroy,Ibrahim Jubber,Aidan P Noon,Derek J Rosario,Jon Griffin,Susan Morgan,Rachel Hubbard,Steve Kennish,Stephen Mitchell,Suresh Venugopal,Kate Linton,Ramanan Rajasundaram,Syed A Hussain,James W F Catto","doi":"10.1111/bju.16516","DOIUrl":"https://doi.org/10.1111/bju.16516","url":null,"abstract":"OBJECTIVETo report real-world outcomes for high-risk non-muscle-invasive bladder cancer (HRNMIBC), including bacillus Calmette-Guérin (BCG) and radical cystectomy (RC), as randomised comparisons of these have not been possible.METHODSWe detail consecutive participants screened for the BRAVO randomised controlled trial comparing RC with BCG (International Standard Randomised Controlled Trial Number [ISRCTN]12509361). Patients were prospectively registered and case-note review used for outcomes. The primary outcome was overall survival. Secondary outcomes included recurrence, progression, metastasis, and bladder cancer-specific survival.RESULTS AND LIMITATIONSA total of 193 patients were screened, including 106 (54.9%) who received BCG, 43 (22.3%) primary RC, 37 (19.2%) 'other' treatment and seven (3.6%) hyperthermic intravesical mitomycin C. All-cause death occurred in 55 (28.5%) patients at median (interquartile range [IQR]) of 29.0 (19.5-42.0) months. In multivariable analysis, overall mortality was more common in older patients (hazard ratio [HR] 2.63, 95% confidence interval [CI] 1.35-5.13; Cox P = 0.004 for age >70 years), those recruited from district hospitals (HR 0.53, 95% CI 0.3-0.95; P = 0.032) and those who did not undergo RC as their first treatment (HR 2.16, 95% CI 1.17-3.99; P = 0.014). In all, 17 (8.8%) patients died from bladder cancer (BC) at median (IQR) of 22.5 (19-36.25) months. In multivariable analysis, BC-specific mortality was more common in older patients (HR 4.87, 95% CI 1.1-21.6; P = 0.037) and those with Tis/T1 disease (HR 2.26, 95% CI 1.23-4.16; P = 0.008) but did not vary with initial treatment.CONCLUSIONSPatients with HRNMIBC are at high-risk of mortality. Those choosing RC as their initial treatment have lower risks of mortality than others, although this may reflect fitness and selection.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"120 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142324932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"October's reviewers of the month","authors":"","doi":"10.1111/bju.16524","DOIUrl":"https://doi.org/10.1111/bju.16524","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"134 4","pages":"509"},"PeriodicalIF":3.7,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142313307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew M. Fang, Justin R. Gregg, Curtis Pettaway, Jingfei Ma, Janio Szklaruk, Tharakeswara K. Bathala, Devaki Shilpa S. Surasi, Brian F. Chapin
{"title":"Whole‐body MRI for staging prostate cancer: a narrative review","authors":"Andrew M. Fang, Justin R. Gregg, Curtis Pettaway, Jingfei Ma, Janio Szklaruk, Tharakeswara K. Bathala, Devaki Shilpa S. Surasi, Brian F. Chapin","doi":"10.1111/bju.16514","DOIUrl":"https://doi.org/10.1111/bju.16514","url":null,"abstract":"ObjectiveTo present a narrative review regarding the diagnostic accuracy of whole‐body magnetic resonance imaging (WBMRI) in staging patients with high‐risk prostate cancer (HRPCa) and compare it to established imaging modalities.MethodsA narrative review was carried out using PubMed using the following keywords: ‘whole body’, ‘magnetic resonance imaging’, ‘MRI’, ‘prostate cancer’, ‘risk stratification’, and ‘staging’. Articles that evaluated WBMRI as the imaging modality to stage patients with HRPCa were included, while studies that solely assessed for biochemical recurrence or metastatic disease progression were excluded.ResultsIn the evaluation of lymphatic metastases, WBMRI has demonstrated a comparable, if not improved, sensitivity and specificity compared to conventional imaging of computed tomography (CT). Furthermore, WBMRI demonstrates improved sensitivity and specificity in detecting bone metastases compared to bone scintigraphy (BS). However, with advent of prostate‐specific membrane antigen (PSMA) radioligands for positron emission tomography (PET), the diagnostic performance of WBMRI to detect metastatic disease appears inferior.ConclusionsThe diagnostic capabilities of WBMRI exceed that of conventional imaging of CT and BS in detecting metastatic disease in patients with HRPCa. However, WBMRI does not perform as well as PSMA PET/CT. Further study on cost comparisons between WBMRI and PSMA PET/CT are needed, as well as evaluations of combined PSMA PET/MRI are needed.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"601 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142276941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}