Case reports in nephrology and urology最新文献_第4页

Acute Kidney Injury due to Crescentic Glomerulonephritis in a Patient with Polycystic Kidney Disease. 多囊肾病患者新月形肾小球肾炎致急性肾损伤1例。

Case reports in nephrology and urology Pub Date : 2013-07-11 Print Date: 2013-07-01 DOI: 10.1159/000353850

Reuben Maggard, Raafat Makary, Carmela L Monteiro, Leighton R James

引用次数: 1

A Rare Case of Type I RenalTubular Acidosis with Membranous Nephropathy Presenting as Hypokalemic Paralysis. 罕见的1型肾小管性酸中毒伴膜性肾病，表现为低钾性麻痹。

Case reports in nephrology and urology Pub Date : 2013-07-01 Print Date: 2013-06-01 DOI: 10.1159/000353768

Sham Sunder, Satyanand Sathi, K Venkataramanan, Himanshu Verma, Minakshi Bhardwaj, J Rajesh, Himanshu Mahapatra

引用次数: 3

Rosuvastatin-induced acute interstitial nephritis. 瑞舒伐他汀致急性间质性肾炎。

Case reports in nephrology and urology Pub Date : 2013-06-13 eCollection Date: 2013-01-01 DOI: 10.1159/000353175

Francesco Londrino, Tito Zattera, Valeria Falqui, Valentina Corbani, Marco Cavallini, Teseo Stefanini, Nadia Chiappini, Michela Ardini, Valentina Martina, Giuseppe Rombolà

{"title":"Rosuvastatin-induced acute interstitial nephritis.","authors":"Francesco Londrino, Tito Zattera, Valeria Falqui, Valentina Corbani, Marco Cavallini, Teseo Stefanini, Nadia Chiappini, Michela Ardini, Valentina Martina, Giuseppe Rombolà","doi":"10.1159/000353175","DOIUrl":"https://doi.org/10.1159/000353175","url":null,"abstract":"We report a case of acute interstitial nephritis (AIN), most likely induced by rosuvastatin, in an 83-year-old male patient. The patient underwent angioplasty of the left internal carotid artery, after which he began a regimen of rosuvastatin (20 mg/day). After 3 weeks the patient was admitted to our unit for acute renal failure with mild proteinuria with negligible urinary sediment. A left kidney biopsy showed dense interstitial infiltrates, mainly composed of lymphocytes with evident tubulitis. Rosuvastatin withdrawal plus prednisolone (1 mg/kg/day) treatment, which was slowly tapered over a period of 4 weeks, allowed for a complete recovery of renal function. To our knowledge, this is the first case report of rosuvastatin-induced AIN. Acute renal failure is associated with a clear increase in morbidity, length of hospital stay and mortality. Moreover, since statins are among the most widely prescribed drugs in Western countries, we think that the risk of AIN should be taken into account as a possible side effect of rosuvastatin. ","PeriodicalId":89663,"journal":{"name":"Case reports in nephrology and urology","volume":" ","pages":"87-90"},"PeriodicalIF":0.0,"publicationDate":"2013-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000353175","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40272922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Delayed progression to dialysis with early and intensive management of predialysis chronic kidney disease: a case-based approach. 透析前慢性肾病的早期和强化管理延迟透析进展:一种基于病例的方法。

Case reports in nephrology and urology Pub Date : 2013-06-11 eCollection Date: 2013-01-01 DOI: 10.1159/000353265

Stephen Thomsen

{"title":"Delayed progression to dialysis with early and intensive management of predialysis chronic kidney disease: a case-based approach.","authors":"Stephen Thomsen","doi":"10.1159/000353265","DOIUrl":"https://doi.org/10.1159/000353265","url":null,"abstract":"In addition to hypertension and diabetes, disorders in mineral metabolism and bone disease (e.g. affecting phosphorus, calcium, parathyroid hormone, and vitamin D) are common complications of chronic kidney disease (CKD) and contribute to morbidity and mortality. Consequently, CKD requires multifactorial treatment to slow CKD progression and avoid end-stage renal disease. CKD progression and treatment outcomes are monitored by measuring the estimated glomerular filtration rate (eGFR), which decreases by 2-12 ml/min/1.73 m(2) per year depending on the stage of CKD and comorbidities, such as diabetes. This paper presents representative case studies illustrating the delay and reversal of CKD progression with comprehensive, individualized treatment regimens, including non-calcium phosphate binders, antihypertensives, lipid-lowering drugs, calcimimetics, and other drugs as required, to treat each component of CKD including CKD-mineral and bone disorder. Four patients are included, with an average age of 70-81 years and CKD stage 3 or 4 accompanied by various comorbidities, most notably diabetes and hypertension. The range of treatment and follow-up durations was 6-7 years. In each case, there was evidence of slowing or prevention of CKD progression, according to eGFR and serum creatinine, regardless of the patient's age or CKD stage. Despite a baseline eGFR of <20 ml/min/1.73 m(2) in 1 female patient, after 6 years of follow-up, her eGFR had stabilized and was maintained at >15 ml/min/1.73 m(2). These observations reinforce the value of early nephrology referral and comprehensive management of CKD and underlying conditions (hypertension and diabetes) beginning at eGFR <60 ml/min/1.73 m(2). ","PeriodicalId":89663,"journal":{"name":"Case reports in nephrology and urology","volume":" ","pages":"74-86"},"PeriodicalIF":0.0,"publicationDate":"2013-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000353265","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40272921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A case of malignancy-associated cryoglobulinemia. 恶性肿瘤相关冷球蛋白血症1例。

Case reports in nephrology and urology Pub Date : 2013-06-11 eCollection Date: 2013-01-01 DOI: 10.1159/000353170

C Kennedy, R Doyle, N Mayer, M Clarkson

引用次数: 0

A case of arteriovenous fistula after renal biopsy in an IgA nephropathy patient with macroscopic hematuria. IgA肾病伴肉眼血尿患者肾活检后出现动静脉瘘1例。

Case reports in nephrology and urology Pub Date : 2013-05-17 eCollection Date: 2013-01-01 DOI: 10.1159/000351510

Satoshi Horikoshi, Akiko Takahata, Akihiko Shiraishi, Hiromitsu Fukuda, Isao Ohsawa, Ryohei Kuwatsuru, Yasuhiko Tomino

引用次数: 2

Disseminated mucormycosis in a patient with recent kidney transplantation: a case report and review of the literature. 一名近期接受肾移植的患者体内的播散性粘孢子菌病：病例报告和文献综述。

Case reports in nephrology and urology Pub Date : 2013-05-07 eCollection Date: 2013-01-01 DOI: 10.1159/000351517

Mohamad Hazem Hatahet, Mohanram Narayanan, Constance Cleaves, Riyam Zreik

{"title":"Disseminated mucormycosis in a patient with recent kidney transplantation: a case report and review of the literature.","authors":"Mohamad Hazem Hatahet, Mohanram Narayanan, Constance Cleaves, Riyam Zreik","doi":"10.1159/000351517","DOIUrl":"10.1159/000351517","url":null,"abstract":"Mucormycosis is an invasive fungal infection commonly seen in diabetics and immunocompromised patients. We report a case of disseminated mucormycosis in a 47-year-old diabetic male who underwent deceased donor renal allograft transplantation about 5 weeks prior to presentation. Our patient presented with increasing fatigue, diarrhea and oligoanuria and was found to have significant acute kidney injury. Doppler ultrasound of the allograft revealed segmental decreased renal perfusion in the upper pole of the allograft with moderate hydronephrosis. Nephrostomy tube placement yielded minimal urine output. An allograft biopsy showed diffuse C4d-positive staining and fungal hyphae suggestive of Mucor infection. Computed tomography (CT) imaging revealed a right upper lobe mass, a small hypodensity in the liver and normal findings in the head. Despite prompt management including discontinuation of immunosuppression, amphotericin B and allograft nephrectomy, the patient had a rapid decompensation, developed respiratory failure requiring intubation, hypotension and supraventricular tachycardia with multiple new areas of hypoattenuation on head CT - all of which ultimately resulted in his death. A review of the literature revealed that mucormycosis is a relatively rare disease with a cumulative 12-month incidence rate of 0.07% in solid organ transplant recipients. Disseminated disease was found in about 23% of cases, with a mortality rate of 96%. ","PeriodicalId":89663,"journal":{"name":"Case reports in nephrology and urology","volume":" ","pages":"58-63"},"PeriodicalIF":0.0,"publicationDate":"2013-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bb/a6/cru-0003-0058.PMC3808793.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40272448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Initially Nondiagnosed Fabry's Disease when Electron Microscopy Is Lacking: The Continuing Story of Focal and Segmental Glomerulosclerosis. 当缺乏电子显微镜时，最初未诊断的法布里病:局灶性和节段性肾小球硬化的持续故事。

Case reports in nephrology and urology Pub Date : 2013-05-04 eCollection Date: 2013-01-01 DOI: 10.1159/000351516

H Trimarchi, A Karl, M S Raña, M Forrester, V Pomeranz, F Lombi, A Iotti

{"title":"Initially Nondiagnosed Fabry's Disease when Electron Microscopy Is Lacking: The Continuing Story of Focal and Segmental Glomerulosclerosis.","authors":"H Trimarchi, A Karl, M S Raña, M Forrester, V Pomeranz, F Lombi, A Iotti","doi":"10.1159/000351516","DOIUrl":"https://doi.org/10.1159/000351516","url":null,"abstract":"Focal and segmental glomerulosclerosis is classified as either primary or secondary. We present a patient with a past history of biopsy-proven focal and segmental glomerulosclerosis. Despite initial response to dual blockade and steroids, proteinuria raised when steroids were decreased. After the patient was restarted on steroids, proteinuria did not improve. Another biopsy confirmed the previous diagnosis but suggested Fabry's disease, later confirmed by electron microscopy, α-galactosidase A serum and leukocyte deficiency as well as genetic studies. Proteinuria decreased when agalsidase β was prescribed in parallel with steroid tapering, increased with steroid discontinuation and improved with meprednisone administration. This report highlights the relevance of electron microscopy in kidney biopsy. In glomerulosclerosis, despite specific treatment, secondary hemodynamic and immunologic pathways may contribute to the development of proteinuria and accelerate the renal disease progression due to the primary disease. We discuss possible pathophysiologic pathways involved in proteinuria in Fabry's disease according to the biopsy and the therapeutic response. ","PeriodicalId":89663,"journal":{"name":"Case reports in nephrology and urology","volume":" ","pages":"51-7"},"PeriodicalIF":0.0,"publicationDate":"2013-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000351516","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40272447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Hyponatremia - a rare but serious complication of amiodarone: a case report and review of the literature. 低钠血症-胺碘酮罕见但严重的并发症:1例报告及文献复习。

Case reports in nephrology and urology Pub Date : 2013-04-19 Print Date: 2013-01-01 DOI: 10.1159/000350910

Linh Pham, Andrea J Shaer, Thomas Marnejon

{"title":"Hyponatremia - a rare but serious complication of amiodarone: a case report and review of the literature.","authors":"Linh Pham, Andrea J Shaer, Thomas Marnejon","doi":"10.1159/000350910","DOIUrl":"https://doi.org/10.1159/000350910","url":null,"abstract":"Introduction: Hyponatremia secondary to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) during amiodarone therapy is a rare but potentially lethal adverse effect. We report a case of severe hyponatremia associated with amiodarone, and discuss its clinical implications.Case report: An 84-year-old Caucasian man with a past medical history of hypertension and diabetes was admitted to the hospital with a non-ST elevation myocardial infarction. He underwent coronary artery bypass graft and developed atrial fibrillation on postoperative day 2. A loading dose of amiodarone followed by a maintenance dose was started. The serum sodium level was 136 mmol/l at discharge and subsequently decreased to 105 mmol/l 11 days later, at which time the patient represented with altered mental status. The diagnosis of SIADH was made based on euvolemic hypoosmotic hyponatremia, lack of any other medication known to cause SIADH and urine that was less than maximally dilute. The serum sodium increased gradually to 123 mmol/l after 36 h of treatment with hypertonic saline, demeclocycline and fluid restriction.Conclusion: SIADH-induced hyponatremia associated with amiodarone occurs rarely. Since severe hyponatremia is associated with significant neurological damage and mortality, clinicians should carefully monitor serum sodium during amiodarone therapy.","PeriodicalId":89663,"journal":{"name":"Case reports in nephrology and urology","volume":"3 1","pages":"46-50"},"PeriodicalIF":0.0,"publicationDate":"2013-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000350910","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31442051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Secondary membranous nephropathy associated with guillain-barré syndrome. 继发性膜性肾病与格林-巴罗综合征相关。

Case reports in nephrology and urology Pub Date : 2013-04-10 Print Date: 2013-01-01 DOI: 10.1159/000350903

Edward J Filippone, Mitul Kanzaria, Rodney Bell, Eric Newman, John L Farber

引用次数: 2