Advances in genomics and genetics最新文献_第6页

Genetic analysis of some characters related to yield in vegetable soybean (Glycine max (L.) Merrill) 菜用大豆(Glycine max (L.))产量相关性状的遗传分析美林)

Advances in genomics and genetics Pub Date : 2012-04-12 DOI: 10.14456/TJG.2011.13

Saranyu Thaworn, R. Juwattanasomran, S. Kongchuensin, W. Kasettranun

引用次数: 1

Assessing genetic diversity of Andrographis paniculata (Burm. f.) Nees, an important medicinal plant of Thailand using RAPD markers 穿心莲的遗传多样性评价。f。)利用RAPD标记分析泰国重要药用植物Nees

Advances in genomics and genetics Pub Date : 2012-04-12 DOI: 10.14456/TJG.2011.4

Parwat Wijarat, V. Keeratinijakal, T. Toojinda, A. Vanavichit, S. Tragoonrung

{"title":"Assessing genetic diversity of Andrographis paniculata (Burm. f.) Nees, an important medicinal plant of Thailand using RAPD markers","authors":"Parwat Wijarat, V. Keeratinijakal, T. Toojinda, A. Vanavichit, S. Tragoonrung","doi":"10.14456/TJG.2011.4","DOIUrl":"https://doi.org/10.14456/TJG.2011.4","url":null,"abstract":"“Fha-Tha-Laai-Joan” ( Andrographis paniculata (Burm. f.) Nees is a medicinal plant widely used in Thailand and some other countries for therapeutic valued, but the lack of their genetic information may cause confusion in its utilization. The Randomly Amplified Polymorphic DNA (RAPD) markers were used to identify and elucidate the phylogenetic relationships among 58 accessions of A. paniculata collected throughout Thailand. Of thirty random primers tested, only eight primers generated a total of 66 bands, of which 26 bands were polymorphic, with an average of 10.5 bands per primer pair. Polymorphic information content (PIC) ranging from 0.034 to 0.405 with an average of 0.172 and 77.59% of A. paniculata accessions showed low PIC scores in a range between 0.00-0.068, indicating low diversity in these accessions. An effective number of allele per locus ( n e ) as 1.018 and very low expected heterozygosity ( H e ), with 0.21 were detected. Genetic similarities of 66 RAPD profiles were estimated via the Jaccard’s coefficient and then the data were processed using UPGMA clustering method. The phylogenetic tree derived from RAPD data revealed that A. paniculata were divided into only one group in which the high similarity values were between 0.81-1.00. The results obtained can be indicated that the distributions of A. paniculata among each region are likely to belong to the same variety and are relatively undifferentiated across a large geographic range.","PeriodicalId":89652,"journal":{"name":"Advances in genomics and genetics","volume":"53 1","pages":"115-125"},"PeriodicalIF":0.0,"publicationDate":"2012-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74024953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

DNA methylation and genetic study of interspecific hybridization in Jatropha curcas L. 麻疯树DNA甲基化及种间杂交遗传研究。

Advances in genomics and genetics Pub Date : 2012-04-12 DOI: 10.14456/TJG.2011.5

Sirinan Suwannoi, T. Kanchanaketu, P. Kusolkumbot, N. Sangduen, V. Hongtrakul

{"title":"DNA methylation and genetic study of interspecific hybridization in Jatropha curcas L.","authors":"Sirinan Suwannoi, T. Kanchanaketu, P. Kusolkumbot, N. Sangduen, V. Hongtrakul","doi":"10.14456/TJG.2011.5","DOIUrl":"https://doi.org/10.14456/TJG.2011.5","url":null,"abstract":"Genetic relationship among Jatropha curcas L., J. gossypifolia L., J. integerrima Jacq ., J. podagrica Hook., J. multifida L. and Ricinus communis L. was studied using 10 AFLP primer pairs. A total of 564 DNA bands were generated and used for cluster analysis. Using UPGMA method, R. communis was clearly separated from Jatropha spp, as well as separated the Jatropha spp. into two groups. The first group comprised of J. curcas , J. integerrima and J. podagrica , whereas the second group consisted of J. multifida and J. gossypifolia . The interspecific hybridization was carried out between J. curcas and other Jatropha species. The results showed that cross between J. curcas and J. integerrima was the most successful. However, some hybrids were also obtained from J. curcas x J. podagrica and J. curcas x J. multifida . The observed ratio of female and male flowers of hybrids from J. curcas and J. integerrima were 1:9.1 to 1:14.9 which fall between two parents. Percentage of methylation in all hybrid derived from J. curcas x J. integerrima was lower than that of the parents. Principal component analysis of methylation fingerprints revealed that the pattern of DNA methylation in all hybrids from J. curcas x J. integerrima was more similar to J. curcas than J. integerrima. Meiotic cells of the hybrids from J. curcas x J. integerrima, J. curcas x J. podagrica and J. curcas x J. multifida were also studied. Majority of the cells investigated were normal. However, some abnormal tetrads were observed in some cells of hybrids.","PeriodicalId":89652,"journal":{"name":"Advances in genomics and genetics","volume":"62 1","pages":"94-105"},"PeriodicalIF":0.0,"publicationDate":"2012-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76156764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Screening Thai landrace rice for blast resistance gene Pi9, Pi36, Pigm(t) using DNA markers 利用DNA标记筛选泰国地方水稻抗稻瘟病基因Pi9、Pi36、Pigm(t)

Advances in genomics and genetics Pub Date : 2012-04-02 DOI: 10.14456/TJG.2011.8

Kritkittisak Phaitreejit, Eng-orn Srikaew, C. Jantasuriyarat, Tanee Sriwongchai, Sureeporn Kate-ngam

引用次数: 2

The genomics and genetics of endometrial cancer. 子宫内膜癌的基因组学和遗传学。

Advances in genomics and genetics Pub Date : 2012-03-01 DOI: 10.2147/AGG.S28953

Andrea J O'Hara, Daphne W Bell

{"title":"The genomics and genetics of endometrial cancer.","authors":"Andrea J O'Hara, Daphne W Bell","doi":"10.2147/AGG.S28953","DOIUrl":"10.2147/AGG.S28953","url":null,"abstract":"<p><p>Most sporadic endometrial cancers (ECs) can be histologically classified as endometrioid, serous, or clear cell. Each histotype has a distinct natural history, clinical behavior, and genetic etiology. Endometrioid ECs have an overall favorable prognosis. They are typified by high frequency genomic alterations affecting PIK3CA, PIK3R1, PTEN, KRAS, FGFR2, ARID1A (BAF250a), and CTNNB1 (β-catenin), as well as epigenetic silencing of MLH1 resulting in microsatellite instability. Serous and clear cell ECs are clinically aggressive tumors that are rare at presentation but account for a disproportionate fraction of all endometrial cancer deaths. Serous ECs tend to be aneuploid and are typified by frequent genomic alterations affecting TP53 (p53), PPP2R1A, HER-2/ERBB2, PIK3CA, and PTEN; additionally, they display dysregulation of E-cadherin, p16, cyclin E, and BAF250a. The genetic etiology of clear cell ECs resembles that of serous ECs, but it remains relatively poorly defined. A detailed discussion of the characteristic patterns of genomic alterations that distinguish the three major histotypes of endometrial cancer is reviewed herein.</p>","PeriodicalId":89652,"journal":{"name":"Advances in genomics and genetics","volume":"2012 2","pages":"33-47"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415201/pdf/nihms384557.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30830051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leaf polarity establishment and the two sets of regulators 叶片极性的建立和两套调节器

Advances in genomics and genetics Pub Date : 2012-01-01 DOI: 10.14456/TJG.2012.8

Chokchai Kittiwongwattana

引用次数: 0

Predominant genotypes and alleles of the Val-9Ala polymorphisms in the mitochondrial targeting sequence leading the manganese superoxide dismutase gene associated with their superoxide dismutase activity and total antioxidant status of healthy Thai subjec 健康泰国人锰超氧化物歧化酶基因的线粒体靶向序列Val-9Ala多态性的主要基因型和等位基因与其超氧化物歧化酶活性和总抗氧化状态相关

Advances in genomics and genetics Pub Date : 2012-01-01 DOI: 10.14456/TJG.2012.4

W. Attatippaholkun, Kornwipa Wikainapakul, S. Waikakul, S. Tunsakul

{"title":"Predominant genotypes and alleles of the Val-9Ala polymorphisms in the mitochondrial targeting sequence leading the manganese superoxide dismutase gene associated with their superoxide dismutase activity and total antioxidant status of healthy Thai subjec","authors":"W. Attatippaholkun, Kornwipa Wikainapakul, S. Waikakul, S. Tunsakul","doi":"10.14456/TJG.2012.4","DOIUrl":"https://doi.org/10.14456/TJG.2012.4","url":null,"abstract":"Genotype distributions and allele frequencies of the Val-9Ala polymorphisms in the mitochondrial targeting sequence leading the manganese superoxide dismutase gene as well as associations with their superoxide dismutase activity and total antioxidant status of healthy Thai subjects were determined. The Val-9Ala polymorphisms in MTS-MnSOD gene of 221 healthy Thais including 135 females and 86 males were genotyped by a real-time PCR using protocol and all reagents of TaqMan Allelic Discrimination Demonstration Kit (PE Applied Biosystem, USA). The SOD activity of whole blood cells and plasma total antioxidant status (TAS) of each subject were assayed manually using protocol and all reagents of RANSOD and TAS kits (Randox Laboratories,UK) respectively. The Val/Val, Val/Ala genotypes and the Val allele frequency were found to be predominant rather than the Ala/Ala genotype and the Ala allele frequency in healthy Thai subjects both females and males similar to those previous reports of healthy Chinese, Japanese and Korean subjects. The average values of SOD activity and TAS level in healthy Thais were 2,129.±778 U/g Hb and 1.27±0.26 mmol/L respectively. The association of each genotype with SOD activity as well as TAS levels of Thai females and males showed that the average values of SOD activity and TAS in healthy Thais with the Val/Val and the Val/Ala genotypes were not statistically different (p>0.05) and not lower than those of the Ala/Ala genotypes. In conclusion, the predominant genotypes were the Val/Val and the Val/Ala and they were not associated with low levels of SOD and TAS.","PeriodicalId":89652,"journal":{"name":"Advances in genomics and genetics","volume":"30 1","pages":"89-103"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79683818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Genetic strategies to accomplish cellulosic ethanol production 实现纤维素乙醇生产的遗传策略

Advances in genomics and genetics Pub Date : 2011-01-01 DOI: 10.14456/TJG.2011.12

Tanathorn Vitisant, Chompunuch Virunanon, W. Chulalaksananukul

{"title":"Genetic strategies to accomplish cellulosic ethanol production","authors":"Tanathorn Vitisant, Chompunuch Virunanon, W. Chulalaksananukul","doi":"10.14456/TJG.2011.12","DOIUrl":"https://doi.org/10.14456/TJG.2011.12","url":null,"abstract":"Cellulosic ethanol production is one of thefuels which play an important role for human naturein the near future. However, ethanol production atpresent uses sugar feedstock substrate from sugarcane and starch from cassava. These substrates arefood resources for human and animals thus are notappropriate substrates for liquid fuel production. Forthis reason, cellulosic biomass from cellulose andhemicellulose is an alternative option for liquid fuelproduction to overcome competitive problems onfood cultivated area. However, higher cost ofcellulosic ethanol production than petroleum fuels is an important issue that has an impact on liquid fuelmanufacture. In this review, useful strategies forcellulosic ethanol process improvement aredescribed in order to create potent alternative energywith economically and commercially acceptableprofit. The strategies can be divided into three parts:first, production of hydrolysis enzyme by plant;second, pretreatment of biomass by controllinglignin and cellulose property; and third, increasingpolysaccharide amount in biomass for ethanolfermentation. In sumary, all strategies will beenhanced together to access the goal to develop theuse of cellulosic ethanol in the near future.","PeriodicalId":89652,"journal":{"name":"Advances in genomics and genetics","volume":"76 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91222015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0