{"title":"Welcome Letter","authors":"","doi":"10.1111/bdi.13471","DOIUrl":"https://doi.org/10.1111/bdi.13471","url":null,"abstract":"<p>Welcome to the 26th Annual Conference of the International Society for Bipolar Disorders! The annual meeting brings together experts in bipolar disorders including researchers, educators, clinicians, and experts by experience. We are a global organization with representation from over 20 countries. Over three jam-packed days in Reykjavik, a first-time location for ISBD, we will share knowledge and wisdom about mood disorders. Through improved understanding of the causes and treatments for these conditions, we will be better prepared to support those we serve.</p><p>Meaningfully, 2024 marks the 30th anniversary of ISBD's inception. In 1994, Drs. David Kupfer and Ellen Frank hosted the first International Conference on Bipolar Disorders (ICBD), the precursor to ISBD, in Pittsburgh, Pennsylvania. An eager group of researchers and clinicians gathered on the University of Pittsburgh campus from June 23–24, 1994, for the latest updates on bipolar disorder. On June 17, 1999, ISBD was officially launched in Pittsburgh during the 3rd biennial ICBD meeting. Guided by Dr. Kupfer's vision for an international community of experts who gather regularly to share scientific advances and engage in advocacy for equitable research funding for bipolar disorders, ISBD was born. Thirty years later, ISBD is alive and well.</p><p>Selected from an outstanding pool of submissions, this year's program comprises 30 symposia, six workshops, 66 oral reports, and two poster sessions. We will also host the Women's Initiative to support gender diversity in our Society and an Early-Mid Career Committee networking session to advance the up-and-coming leaders in our field.</p><p>Among our truly exceptional line-up of presentations, I would like to highlight six invited plenary talks: <i>My Bipolar Journey</i> (Leah Charles-King), <i>Debate on Antidepressant Medication for Bipolar Disorder</i> (Ralph Kupka, Eduard Vieta, Lakshmi Yatham), <i>Genetic Architecture of Bipolar Disorder: Knowns and Unknowns</i> (Ole A. Andreassen), <i>From Speech to Emotion to Mood: Mental Health Modeling in Natural Environments</i> (Emily Mower Provost), <i>Older Age Bipolar Disorder: Cognitive and Somatic Comorbidities (</i>Annemiek Dols<i>), and Ongoing Bipolar Mood Instability: What Can, or Could, Psychological Interventions Offer?</i> (Kim Wright). Don't miss any of them!</p><p>Because of the large number of outstanding submissions this year, we expanded our oral report offerings. With 66 presentations, it is impossible to highlight all of them, but I wanted to call your attention to just a few offerings to give you a taste of the feast awaiting us: <i>Polygenic Scores and Mood Disorder Risk in Context of Family History and Developmental Psychopathology</i> (Rudolf Uher), <i>Elucidating Neurovascular Dynamics in Bipolar Disorder with Patient-Derived Vascularized Cerebral Organoids</i> (Annie Kathuria), <i>Fostering Network Opportunities and Creating a Community of Early and Mid-Career Members of t","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"26 S1","pages":"6"},"PeriodicalIF":5.0,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bdi.13471","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142244556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ajay K. Parsaik, Aanchal Chaudhary, Shivy Sharma, Brooke Ellen Delgoffe, Rachel Gabor, Balwinder Singh
{"title":"Effects of long-term lithium therapy on kidney functioning in mood disorders: A population-based historical cohort study","authors":"Ajay K. Parsaik, Aanchal Chaudhary, Shivy Sharma, Brooke Ellen Delgoffe, Rachel Gabor, Balwinder Singh","doi":"10.1111/bdi.13501","DOIUrl":"https://doi.org/10.1111/bdi.13501","url":null,"abstract":"Lithium is Food and Drug Administration-approved for bipolar disorder (BD) and is also used in depressive disorders but is underutilized due to concerns about chronic kidney disease (CKD). We explored clinical and demographic profiles of patients on long-term lithium therapy (LTLT) and assessed kidney function. Our aims were to identify the predictors for CKD stage ≥3 and the impact of lithium discontinuation post-CKD diagnosis.","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"3 1","pages":""},"PeriodicalIF":5.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer B. Levin, Melissa DelBello, Avani C. Modi, Farren Briggs, Larry F. Forthun, Molly McVoy, Joy Yala, Raechel Cooley, Jessica Black, Carla Conroy, Martha Sajatovic
{"title":"A 6-month, prospective, randomized controlled trial of customized adherence enhancement versus a bipolar-specific educational control in poorly adherent adolescents and young adults living with bipolar disorder","authors":"Jennifer B. Levin, Melissa DelBello, Avani C. Modi, Farren Briggs, Larry F. Forthun, Molly McVoy, Joy Yala, Raechel Cooley, Jessica Black, Carla Conroy, Martha Sajatovic","doi":"10.1111/bdi.13489","DOIUrl":"10.1111/bdi.13489","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Few studies have addressed medication adherence in adolescents and young adults (AYAs) with bipolar disorder (BD). This 6-month prospective randomized-controlled trial (RCT) tested customized adherence enhancement for adolescents and young adults (CAE-AYA), a behavioral intervention for AYAs versus enhanced treatment as usual (ETAU).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Inclusion criteria were AYAs age 13–21 with BD type I or II with suboptimal adherence defined as missing ≥20% of medications. Assessments were conducted at Screening, Baseline, and weeks 8, 12 and 24. Primary outcome was past 7 day self-reported Tablets Routine Questionnaire (TRQ) validated by electronic pillbox monitoring (SimpleMed). Symptom measures included the Hamilton Depression Rating Scale (HAM-D) and Young Mania Rating Scale (YMRS).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean sample age (<i>N</i> = 36) was 19.1 years (SD = 2.0); 66.7% (<i>N</i> = 24) female, BD Type I (81%). The mean missed medication on TRQ for the total sample was 35.4% (SD = 28.8) at screening and 30.4% (SD = 30.5) at baseline. Both CAE-AYA and ETAU improved on TRQ from screening to baseline. Baseline mean missed medication using SimpleMed was 51.6% (SD = 38.5). Baseline HAM-D and YMRS means were 7.1 (SD = 4.7) and 6.0 (SD = 7.3), respectively. Attrition rate at week 24 was 36%. Baseline to 24-week change on TRQ, adjusting for age, gender, educational level, living situation, family history, race, and ethnicity, showed improvement favoring CAE-AYA versus ETAU of 15%. SimpleMed interpretation was limited due to substantial missing data. There was a significant reduction in depression favoring CAE-AYA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>CAE-AYA may improve adherence in AYAs with BD, although conclusions need to be made cautiously given study limitations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Trials Registration</h3>\u0000 \u0000 <p>ClinicalTrials.gov identifier: NCT04348604.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"26 7","pages":"696-707"},"PeriodicalIF":5.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11560489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142131752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of delirious mania in the context of concurrent cardiac comorbidities and autonomic instability.","authors":"Cathy Daichang, Eric Rutkowski, Zeshawn Ali","doi":"10.1111/bdi.13502","DOIUrl":"https://doi.org/10.1111/bdi.13502","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142118922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Postpartum rage attacks in a female with bipolar II disorder and obsessive-compulsive disorder: Diagnostic and treatment challenges.","authors":"Verinder Sharma","doi":"10.1111/bdi.13499","DOIUrl":"https://doi.org/10.1111/bdi.13499","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142118924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"NMDA antagonists use in bipolar depression: A case report.","authors":"Kirolos Ibrahim, Sara Abell, Rif El-Mallakh","doi":"10.1111/bdi.13496","DOIUrl":"https://doi.org/10.1111/bdi.13496","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vincent Zhang, Alexis June Wirtz, Anmol Dhingra, Ashar Zahid, Najeeb Hussain
{"title":"Conceptualizing the relationship between synthetic cannabinoid use and neuroleptic malignant syndrome.","authors":"Vincent Zhang, Alexis June Wirtz, Anmol Dhingra, Ashar Zahid, Najeeb Hussain","doi":"10.1111/bdi.13503","DOIUrl":"https://doi.org/10.1111/bdi.13503","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gin S Malhi, Erica Bell, Uyen Le, Philip Boyce, Michael Berk
{"title":"Treatment resistant but not irremediable.","authors":"Gin S Malhi, Erica Bell, Uyen Le, Philip Boyce, Michael Berk","doi":"10.1111/bdi.13490","DOIUrl":"https://doi.org/10.1111/bdi.13490","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}