{"title":"Yet Why Not Say What Happened?","authors":"Jacqueline W, Ayal Schaffer","doi":"10.1111/bdi.13515","DOIUrl":"https://doi.org/10.1111/bdi.13515","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto Stefana, Paolo Fusar-Poli, Pierluigi Politi, Eduard Vieta, Eric A. Youngstrom
{"title":"Sexual Feelings in the Psychotherapy Room: Comparing Their Occurrence in Patients With Unipolar Depression, Bipolar Disorder, and Neither of These","authors":"Alberto Stefana, Paolo Fusar-Poli, Pierluigi Politi, Eduard Vieta, Eric A. Youngstrom","doi":"10.1111/bdi.13511","DOIUrl":"10.1111/bdi.13511","url":null,"abstract":"<p>We read with interest the paper by Yaghmaei et al. [<span>1</span>], which highlights the significant impact of sexual challenges faced by individuals with bipolar disorder on their quality of life, as well as on their families. Their research underscores the need for early family-tailored sexual health interventions and the importance of recognizing these issues in both diagnostic and therapeutic contexts.</p><p>We agree with Yaghmaei et al. and wish to extend the discussion to another crucial aspect of the lives of these patients: the psychotherapeutic context.</p><p>Changes in the sexual patterns of psychiatric patients are evident not only within their families but also profoundly influence the therapeutic environment and dynamic. For example, behaviors such as innuendo, unsolicited sexual advances, changes in couture and make-up, and even sexual exhibitionism are notable, particularly during certain stages of bipolar illnesses. From its very beginning, the realm of psychotherapy is not immune to these erotic undertones. Most psychotherapists, at various points in their career, will experience romantic or sexual overtures from their patients. In certain situations, these advances can even evoke reciprocal feelings in the therapist. When not properly managed, such dynamics can jeopardize the therapeutic relationship, hinder treatment progress, and, in extreme cases, result in breaches of professional conduct. Although the literature suggests is it not the most common ethical violation providers are sanctioned for [<span>2</span>], sexual misconduct is a serious and recognized issue in the field. Herbert Strean's 1994 publication, “Therapists who have sex with their patients,” continues to be an enlightening read. Pooled data indicate that more than 4% of surveyed mental health professionals surveyed have admitted to crossing sexual boundaries with one or more of their patients [<span>3</span>]. Furthermore, it is crucial to acknowledge that the prevalence and types of ethical violations can vary significantly by region, cultural context, therapist's unresolved personal problems, and the specific group of mental health professionals studied [<span>4</span>].</p><p>A pressing question remains: Are erotic behaviors in therapy sessions more prevalent among patients with bipolar disorder compared to those with other diagnoses? The forthcoming, original data seek to shed some light on this pivotal issue.</p><p>The data presented herein are from a secondary analysis of a cross-sectional study aimed at developing and preliminarily validating a self-report inventory that assesses patients' perceptions and affective reactions to their therapists during psychotherapy sessions [<span>5</span>]. The sample comprised 701 adults diagnosed with psychiatric disorders, all of whom underwent individual psychotherapy and resided in the United States. Participants were recruited from March through April 2022 through two national registers for clinical research ","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"27 1","pages":"69-71"},"PeriodicalIF":5.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bdi.13511","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Character of Depression","authors":"Gin S. Malhi, Erica Bell, Gracie Meng-Cin Tsai, Ching-Wen Hung, Mei-tzu Tsai, Chia-Yi Wu","doi":"10.1111/bdi.13514","DOIUrl":"10.1111/bdi.13514","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"27 1","pages":"72-73"},"PeriodicalIF":5.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronic Serotonin Syndrome Masquerading as Anxiety and Agitation in a Patient With Mood Disorder: A Clinical Dilemma!","authors":"Nicola Keeth, Jonathan G. Leung, Balwinder Singh","doi":"10.1111/bdi.13513","DOIUrl":"10.1111/bdi.13513","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"27 2","pages":"163-165"},"PeriodicalIF":5.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susan K. Service, Juan F. De La Hoz, Ana M. Diaz-Zuluaga, Alejandro Arias, Aditya Pimplaskar, Chuc Luu, Laura Mena, Johanna Valencia-Echeverry, Mauricio Castaño Ramírez, Carrie E. Bearden, Chiara Sabatti, Victor I. Reus, Carlos López-Jaramillo, Nelson B. Freimer, Loes M. Olde Loohuis
{"title":"Predicting Diagnostic Conversion From Major Depressive Disorder to Bipolar Disorder: An EHR Based Study From Colombia","authors":"Susan K. Service, Juan F. De La Hoz, Ana M. Diaz-Zuluaga, Alejandro Arias, Aditya Pimplaskar, Chuc Luu, Laura Mena, Johanna Valencia-Echeverry, Mauricio Castaño Ramírez, Carrie E. Bearden, Chiara Sabatti, Victor I. Reus, Carlos López-Jaramillo, Nelson B. Freimer, Loes M. Olde Loohuis","doi":"10.1111/bdi.13512","DOIUrl":"10.1111/bdi.13512","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Most bipolar disorder (BD) patients initially present with depressive symptoms, resulting in a delayed diagnosis of BD and poor clinical outcomes. This study aims to identify features predictive of the conversion from Major Depressive Disorder (MDD) to BD by leveraging electronic health record (EHR) data from the Clínica San Juan de Dios Manizales in Colombia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We employed a multivariable Cox regression model to identify important predictors of conversion from MDD to BD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Analyzing 15 years of EHR data from 13,607 patients diagnosed with MDD, a total of 1610 (11.8%) transitioned to BD. Predictive features of the conversion to BD included severity of the initial MDD episode, presence of psychosis and hospitalization at first episode, family history of BD, and female gender. Additionally, we observed associations with medication classes (positive associations with prescriptions of mood stabilizers, antipsychotics, and negative associations with antidepressants) and a positive association with suicidality, a feature derived from natural language processing (NLP) of clinical notes. Together, these risk factors predicted BD conversion within 5 years of the initial MDD diagnosis, with a recall of 72% and a precision of 38%.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Our study confirms previously identified risk factors identified through registry-based studies (female gender and psychotic depression at the index MDD episode) and identifies novel ones (suicidality extracted from clinical notes). These results simultaneously demonstrate the validity of using EHR data for predicting BD conversion and underscore its potential for the identification of novel risk factors, thereby improving early diagnosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"27 1","pages":"47-56"},"PeriodicalIF":5.0,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bdi.13512","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patients' Perspectives on the Consequences of Eliminating Prepubertal-Pediatric Bipolar Disorder as a Valid Diagnosis","authors":"Katrin I. Kutlucinar, Kathryn Burrows","doi":"10.1111/bdi.13510","DOIUrl":"10.1111/bdi.13510","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"27 1","pages":"67-68"},"PeriodicalIF":5.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduard Vieta, Mauricio Tohen, Diane McIntosh, Lars Vedel Kessing, Martha Sajatovic, Roger S. McIntyre
{"title":"Early use of long-acting injectable antipsychotics in bipolar disorder type I: An expert consensus","authors":"Eduard Vieta, Mauricio Tohen, Diane McIntosh, Lars Vedel Kessing, Martha Sajatovic, Roger S. McIntyre","doi":"10.1111/bdi.13498","DOIUrl":"10.1111/bdi.13498","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Long-acting injectable antipsychotics (LAIs) are not routinely offered to patients living with bipolar disorder type I (BP-I), despite widespread evidence that supports their benefits over oral antipsychotics, particularly in early disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A round-table meeting of psychiatrists convened to discuss barriers and opportunities and provide consensus recommendations around the early use of LAIs for BP-I.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>LAIs are rarely prescribed to treat BP-I unless a patient has severe symptoms, sub-optimal adherence to oral antipsychotics, or has experienced multiple relapses. Beyond country-specific accessibility issues (e.g., healthcare infrastructure and availability/approval status), primary barriers to the effective use of LAIs were identified as attitudinal and knowledge/experience-based. Direct discussions between healthcare providers and patients about treatment preferences may not occur due to a preconceived notion that patients prefer oral antipsychotics. Moreover, as LAIs have historically been limited to the treatment of schizophrenia and the most severe cases of BP-I, healthcare providers might be unaware of the benefits LAIs provide in the overall management of BP-I. Improved treatment adherence associated with LAIs compared to oral antipsychotics may support improved outcomes for patients (e.g., reduced relapse and hospitalization). Involvement of all stakeholders (healthcare providers, patients, and their supporters) participating in the patient journey is critical in early and shared decision-making processes. Clinical and database studies could potentially bridge knowledge gaps to facilitate acceptance of LAIs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This review discusses the benefits of LAIs in the management of BP-I and identifies barriers to use, while providing expert consensus recommendations for potential solutions to support informed treatment decision-making.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"27 1","pages":"7-16"},"PeriodicalIF":5.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bdi.13498","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142494582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychotherapy online: Bridging the gap between recommendations and reality","authors":"Ralph Kupka, Manja Koenders, Susan Zyto","doi":"10.1111/bdi.13509","DOIUrl":"10.1111/bdi.13509","url":null,"abstract":"<p>There is a simple, layman's version of bipolar disorder: an episodic mental illness with seriously disturbing manic and depressive episodes, and after recovery long periods of euthymia in which all is well again. Medication is effective in the acute symptomatic treatment, and maintenance pharmacotherapy prevents future episodes, if prescribed and taken indefinitely. Psychoeducation will increase insight and awareness of the characteristics of the illness, and thereby facilitate acceptance, self-management, and treatment compliance.</p><p>Anyone who has to deal with bipolar illness, either as a patient, a family member, a caregiver, or a professional, knows that the reality is far more complex. If this is true for the acute management and pharmacotherapy, it is even more for the time after the storm has calmed down. Subsyndromal residual symptoms and mood instability, subtle but annoying cognitive impairments, occupational and interpersonal problems as a result of past manic behavior, an injured self-image, and doubts about what to expect in the future, may all have a negative impact on psychosocial functioning and emotional wellbeing. Highly prevalent comorbid psychiatric conditions like anxiety disorders, personality disorders, and substance abuse further complicate this situation.</p><p>Of the psychological approaches, psychoeducation is now a well-established intervention which is part of standard treatment. In addition, family-focused therapy (FFT), cognitive behavioral therapy (CBT), and interpersonal and social rhythm therapy (IPSRT) are also recommended in most clinical guidelines, in combination with pharmacotherapy. A major concern is: while most treated patients with bipolar disorder will receive pharmacotherapy, and many will have had some form of psychoeducation, how many do get one of these recommended psychotherapies? How many psychologists and psychotherapist have an interest in bipolar disorder, let alone will be trained in these specific interventions? Bipolar disorder has long been viewed as a highly biologically rooted psychiatric illness, where pharmacotherapy is the cornerstone of acute curative and long-term preventive treatment. Moreover, dare psychotherapists treat a person with an anxiety or personality disorder, when she/he also suffers from bipolar disorder? The recently established ISBD Psychological Interventions Taskforce<span><sup>1</sup></span> is a welcome initiative to improve this situation, as is this special issue of Bipolar Disorders Journal.</p><p>Tremain et al.<span><sup>2</sup></span> address several important issues that underscore the potential for psychological treatment in addition to pharmacotherapy and clinical management of mood episodes.</p><p>First, we have to extend treatment of bipolar disorder beyond symptomatic recovery. Van der Voort et al.<span><sup>3</sup></span> showed that functional recovery in recurrent depressive and bipolar disorder seriously lags behind recovery of a depressive ep","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"26 7","pages":"746-747"},"PeriodicalIF":5.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bdi.13509","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142457217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary on ‘Comorbidity of bipolar disorder and borderline personality disorder: Phenomenology, course and treatment considerations’ by Temes et al.","authors":"Roger T. Mulder","doi":"10.1111/bdi.13508","DOIUrl":"10.1111/bdi.13508","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"26 7","pages":"748-749"},"PeriodicalIF":5.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142457216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Holy Grail revisited: What works for whom?","authors":"Holly A. Swartz","doi":"10.1111/bdi.13507","DOIUrl":"10.1111/bdi.13507","url":null,"abstract":"","PeriodicalId":8959,"journal":{"name":"Bipolar Disorders","volume":"26 7","pages":"744-745"},"PeriodicalIF":5.0,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}