Journal of prenatal medicine最新文献_第6页

Placental mesenchymal dysplasia, a case of intrauterine sudden death in a normal-sized fetus. 胎盘间充质发育不良:正常大小胎儿宫内猝死一例。

Journal of prenatal medicine Pub Date : 2013-01-01

Maria Chiara Sudano, Laura D'Emidio, Lucia Mangiafico, Luisa Mobili, Claudio Giorlandino

{"title":"Placental mesenchymal dysplasia, a case of intrauterine sudden death in a normal-sized fetus.","authors":"Maria Chiara Sudano, Laura D'Emidio, Lucia Mangiafico, Luisa Mobili, Claudio Giorlandino","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: placental mesenchymal dysplasia (PMD) is a rare placental anomaly characterized by placentomegaly and grape-like vesicles which resemble molar pregnancy.Case: we report the case of 33-year-old woman (1-gravid) who visited our clinic at 11 weeks of gestation due to a suspected molar pregnancy. Ultrasound examination showed an enlarged placenta with multiple vesicular lesions. Maternal human chorionic gonadotropin level was normal and chorionic villus sampling showed a normal male karyotype (46 XY). The fetus exhibited no specific anomalies and fetal growth was normal during pregnancy with no signs of fetal suffering. At 31 weeks, the pregnancy ended owing to intrauterine fetal death (IUFD). The patient delivered a normal-sized male fetus (1800 g) with no definite anomalies. A pathological examination led to a diagnosis of placental mesenchymal dysplasia.Conclusion: in the presence of placental ultrasound anomalies with no other sign of fetal suffering, the pregnancy should be considered at risk and, therefore, should be monitored carefully including the option of hospitalization.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"7 1","pages":"9-11"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671814/pdf/9-11.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31577704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbetocin versus oxytocin in caesarean section with high risk of post-partum haemorrhage. 催产素与催产素在高危产后出血剖宫产中的应用。

Journal of prenatal medicine Pub Date : 2013-01-01 DOI: 10.11138/JPM/2013.7.1.012

G. Larciprete, Carlotta Montagnoli, M. Frigo, V. Panetta, C. Todde, B. Zuppani, C. Centonze, A. Bompiani, I. Malandrenis, A. Cirese, H. Valensise

{"title":"Carbetocin versus oxytocin in caesarean section with high risk of post-partum haemorrhage.","authors":"G. Larciprete, Carlotta Montagnoli, M. Frigo, V. Panetta, C. Todde, B. Zuppani, C. Centonze, A. Bompiani, I. Malandrenis, A. Cirese, H. Valensise","doi":"10.11138/JPM/2013.7.1.012","DOIUrl":"https://doi.org/10.11138/JPM/2013.7.1.012","url":null,"abstract":"OBJECTIVES the aims of the present study were to compare the haemodynamic effects of oxytocin and carbetocin and to assess the efficacy of these two drugs in terms of blood loss and the additional uterotonic needed in caesarean section at high risk of primary post-partum haemorrhage. METHODS women in the carbetocin group (group A) received a bolus of 100 μg IV; women in the control group (group B) received 20 IU of oxytocin in 1000 ml of 0,9% Na-Cl solution IV (150 mL/hour). The main parameter evaluated was the haemodynamic effects of drugs and the need for additional uterotonic agents. In addition we compared the drop in haemoglobin level, the uterine tone, the uterine fundal state and the diuresis. RESULTS regarding the haemodynamic effects, both drugs have a hypotensive effect, but we found a greater reduction in blood pressure within the oxytocin group. Significantly more women needed additional uterotonic agents in the oxytocin group (23,5% vs 0%, p<0.01), though there was no significant difference in estimated blood loss and in the drop haemoglobin level (p>0.05). There was a significant difference in the diuresis, higher in carbetocin group (1300 ml ± 450 ml vs 1100 ml ± 250 ml, p=0.01). CONCLUSIONS a single injection of carbetocin appears to be more effective than a continuous infusion of oxytocin to prevent the PPH, with a similar haemodynamic profile and minor antidiuretic effect.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"37 1","pages":"12-8"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81369812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 58

Placental mesenchymal dysplasia, a case of intrauterine sudden death in a normal-sized fetus. 胎盘间充质发育不良:正常大小胎儿宫内猝死一例。

Journal of prenatal medicine Pub Date : 2013-01-01 DOI: 10.11138/JPM/2013.7.1.009

Maria Chiara Sudano, L. D'emidio, L. Mangiafico, L. Mobili, C. Giorlandino

{"title":"Placental mesenchymal dysplasia, a case of intrauterine sudden death in a normal-sized fetus.","authors":"Maria Chiara Sudano, L. D'emidio, L. Mangiafico, L. Mobili, C. Giorlandino","doi":"10.11138/JPM/2013.7.1.009","DOIUrl":"https://doi.org/10.11138/JPM/2013.7.1.009","url":null,"abstract":"INTRODUCTION placental mesenchymal dysplasia (PMD) is a rare placental anomaly characterized by placentomegaly and grape-like vesicles which resemble molar pregnancy. CASE we report the case of 33-year-old woman (1-gravid) who visited our clinic at 11 weeks of gestation due to a suspected molar pregnancy. Ultrasound examination showed an enlarged placenta with multiple vesicular lesions. Maternal human chorionic gonadotropin level was normal and chorionic villus sampling showed a normal male karyotype (46 XY). The fetus exhibited no specific anomalies and fetal growth was normal during pregnancy with no signs of fetal suffering. At 31 weeks, the pregnancy ended owing to intrauterine fetal death (IUFD). The patient delivered a normal-sized male fetus (1800 g) with no definite anomalies. A pathological examination led to a diagnosis of placental mesenchymal dysplasia. CONCLUSION in the presence of placental ultrasound anomalies with no other sign of fetal suffering, the pregnancy should be considered at risk and, therefore, should be monitored carefully including the option of hospitalization.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"128 1","pages":"9-11"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87915035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Increased nuchal translucency and short femur length as possible early signs of osteogenesis imperfecta type III. 颈部透明度增加和股骨长度短可能是成骨不全III型的早期症状。

Journal of prenatal medicine Pub Date : 2013-01-01

Antonella Vimercati, Mariantonietta Panzarino, Ilaria Totaro, Annarosa Chincoli, Luigi Selvaggi

{"title":"Increased nuchal translucency and short femur length as possible early signs of osteogenesis imperfecta type III.","authors":"Antonella Vimercati, Mariantonietta Panzarino, Ilaria Totaro, Annarosa Chincoli, Luigi Selvaggi","doi":"","DOIUrl":"","url":null,"abstract":"Objective: this paper reports an association between an increased Nuchal Translucency (NT) and Osteogenesis Imperfecta (OI), a type of skeletal dysplasia. Measurement of fetal NT at 10-14 weeks of gestation is a sensitive and effective screening method for chromosomal abnormalities.Methods: a 35-year- old Caucasian woman in her fourth pregnancy was referred to our clinic for an ultrasound scan at 12 weeks of gestation, that confirmed increased Nuchal Translucency. Chorionic villi sampling was performed, showing a normal karyotype. The patient was evaluated by a team of experienced ultra sonographers for pregnancy follow-up at our Department, that is a tertiary center.Results: in our case the ultrasound scan at 12 week of gestation revealed only an increased NT (3 mm). Cytogenetic analysis on chorionic villi demonstrated a normal male karyotype. US follow-up, performed every 3-4 weeks, confirmed normal anthropometric parameters except for shortening of both femurs, but at 23 weeks an incorrect attitude of the feet was revealed. A clinical and radiographic diagnosis of OI type III was made only at birth, and through follow-up continuing to date.Discussion: NT screening was successful for chromosomal abnormalities at 11-14 weeks of gestation. An increased NT thickness is also associated with numerous fetal anomalies and genetic syndromes in a chromosomally normal fetus. In our case there were no sonographic signs of imperfect osteogenesis in the first trimester, although there was an increased NT with a normal karyotype.Conclusion: currently, in literature, there are not other cases of OI type III associated with an increased NT. Our report is the first to suggest an association between an increased nuchal translucency, short femur length and osteogenesis imperfecta type III.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"7 1","pages":"5-8"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671815/pdf/5-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31486539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbetocin versus oxytocin in caesarean section with high risk of post-partum haemorrhage. 催产素与催产素在高危产后出血剖宫产中的应用。

Journal of prenatal medicine Pub Date : 2013-01-01

Giovanni Larciprete, Carlotta Montagnoli, Mariagrazia Frigo, Valentina Panetta, Cristina Todde, Benedetta Zuppani, Chiara Centonze, Alessandro Bompiani, Ioannis Malandrenis, Alio Cirese, Herbert Valensise

{"title":"Carbetocin versus oxytocin in caesarean section with high risk of post-partum haemorrhage.","authors":"Giovanni Larciprete, Carlotta Montagnoli, Mariagrazia Frigo, Valentina Panetta, Cristina Todde, Benedetta Zuppani, Chiara Centonze, Alessandro Bompiani, Ioannis Malandrenis, Alio Cirese, Herbert Valensise","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: the aims of the present study were to compare the haemodynamic effects of oxytocin and carbetocin and to assess the efficacy of these two drugs in terms of blood loss and the additional uterotonic needed in caesarean section at high risk of primary post-partum haemorrhage.Methods: women in the carbetocin group (group A) received a bolus of 100 μg IV; women in the control group (group B) received 20 IU of oxytocin in 1000 ml of 0,9% Na-Cl solution IV (150 mL/hour). The main parameter evaluated was the haemodynamic effects of drugs and the need for additional uterotonic agents. In addition we compared the drop in haemoglobin level, the uterine tone, the uterine fundal state and the diuresis.Results: regarding the haemodynamic effects, both drugs have a hypotensive effect, but we found a greater reduction in blood pressure within the oxytocin group. Significantly more women needed additional uterotonic agents in the oxytocin group (23,5% vs 0%, p<0.01), though there was no significant difference in estimated blood loss and in the drop haemoglobin level (p>0.05). There was a significant difference in the diuresis, higher in carbetocin group (1300 ml ± 450 ml vs 1100 ml ± 250 ml, p=0.01).Conclusions: a single injection of carbetocin appears to be more effective than a continuous infusion of oxytocin to prevent the PPH, with a similar haemodynamic profile and minor antidiuretic effect.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"7 1","pages":"12-8"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671813/pdf/12-18.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31577705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two cases of complete hydatidiform mole and coexistent live fetus. 完整葡萄胎2例，活胎共存。

Journal of prenatal medicine Pub Date : 2013-01-01 DOI: 10.11138/JPM/2013.7.1.001

A. Vimercati, A. D. de Gennaro, I. Cobuzzi, S. Grasso, M. Abruzzese, F. Fascilla, G. Cormio, L. Selvaggi

{"title":"Two cases of complete hydatidiform mole and coexistent live fetus.","authors":"A. Vimercati, A. D. de Gennaro, I. Cobuzzi, S. Grasso, M. Abruzzese, F. Fascilla, G. Cormio, L. Selvaggi","doi":"10.11138/JPM/2013.7.1.001","DOIUrl":"https://doi.org/10.11138/JPM/2013.7.1.001","url":null,"abstract":"The aim of this study was to report the clinical features, management, and outcome of complete hydatidiform mole with a coexisting viable fetus. Two cases are reported. In both cases ultrasound examination demonstrated a normally growing live fetus alongside a normal placenta and an additional intrauterine echogenic mass with features of hydatidiform mole. The hCG levels were significantly increased and fetal karyotypes were normal. A cesarean section performed at 28 weeks' gestation in the first case and at 26 weeks' gestation in the second one resulted in the delivery of live normal infant and two adjoining placentas in both cases. Microscopic examination of the abnormal placentas confirmed complete hydatidiform mole. The babies did well and serial maternal serum hCG levels showed a declining trend and were undetectable by a few months after delivery. Continuation of a twin pregnancy with complete hydatidiform mole (CHMF) is an acceptable option. There is, although, an increased risk of developing maternal and fetal complications. Close surveillance of an ongoing pregnancy is compulsory to detect potential early signs of complications.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"102 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91229248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 28

Two cases of complete hydatidiform mole and coexistent live fetus. 完整葡萄胎2例，活胎共存。

Journal of prenatal medicine Pub Date : 2013-01-01

Antonella Vimercati, Alessandra Caterina de Gennaro, Isabella Cobuzzi, Silvana Grasso, Marinella Abruzzese, Fabiana Divina Fascilla, Gennaro Cormio, Luigi Selvaggi

{"title":"Two cases of complete hydatidiform mole and coexistent live fetus.","authors":"Antonella Vimercati, Alessandra Caterina de Gennaro, Isabella Cobuzzi, Silvana Grasso, Marinella Abruzzese, Fabiana Divina Fascilla, Gennaro Cormio, Luigi Selvaggi","doi":"","DOIUrl":"","url":null,"abstract":"The aim of this study was to report the clinical features, management, and outcome of complete hydatidiform mole with a coexisting viable fetus. Two cases are reported. In both cases ultrasound examination demonstrated a normally growing live fetus alongside a normal placenta and an additional intrauterine echogenic mass with features of hydatidiform mole. The hCG levels were significantly increased and fetal karyotypes were normal. A cesarean section performed at 28 weeks' gestation in the first case and at 26 weeks' gestation in the second one resulted in the delivery of live normal infant and two adjoining placentas in both cases. Microscopic examination of the abnormal placentas confirmed complete hydatidiform mole. The babies did well and serial maternal serum hCG levels showed a declining trend and were undetectable by a few months after delivery. Continuation of a twin pregnancy with complete hydatidiform mole (CHMF) is an acceptable option. There is, although, an increased risk of developing maternal and fetal complications. Close surveillance of an ongoing pregnancy is compulsory to detect potential early signs of complications.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"7 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671816/pdf/1-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31486538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thyroid physiology and common diseases in pregnancy: review of literature. 妊娠期甲状腺生理与常见疾病:文献综述。

Journal of prenatal medicine Pub Date : 2012-10-01

Pietro Cignini, Ester Valentina Cafà, Claudio Giorlandino, Stella Capriglione, Anna Spata, Nella Dugo

引用次数: 0

Epidemiology and risk factors of amniotic band syndrome, or ADAM sequence. 羊膜带综合征或 ADAM 序列的流行病学和风险因素。

Journal of prenatal medicine Pub Date : 2012-10-01

Pietro Cignini, Claudio Giorlandino, Francesco Padula, Nella Dugo, Ester Valentina Cafà, Anna Spata

{"title":"Epidemiology and risk factors of amniotic band syndrome, or ADAM sequence.","authors":"Pietro Cignini, Claudio Giorlandino, Francesco Padula, Nella Dugo, Ester Valentina Cafà, Anna Spata","doi":"","DOIUrl":"","url":null,"abstract":"Amniotic band sequence (ABS) is the term applied to a wide range of congenital anomalies, most typically limb and digital amputations and constriction rings, that occur in association with fibrous bands (1). These alterations may be associated or not with cutaneous and visceral abnormalities.This work, which is a literature review, examines several studies that relate to cases of amniotic band syndrome (SBA). In particular, our attention was focused on the causes and pathogenesis of the SBA. These for the most part are still unknown, but from what we observe in different jobs, are due to a mechanism of vascular damage. Therefore in this paper we examine chemical risk factors, like smoking, drug use, maternal hyperglycemia, mechanical risk factors such as the puncture of the amniotic sac after amniocentesis. We also speak of the altitude as a risk factor related to blood pressure, of the increased incidence of disease in primigravid, in women with a low level of education, in which the pregnancy was not planned, and then we talk of a higher incidence in young fathers and of the role of familiarity.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"6 4","pages":"59-63"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530965/pdf/59-63_pietro_cignini_def.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31149810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sudden intrauterine unexplained death: time for change. 突如其来的宫内不明原因死亡:是时候改变了。

Journal of prenatal medicine Pub Date : 2012-10-01

Claudio Giorlandino, Alvaro Mesoraca, Pietro Cignini

引用次数: 0