Journal of prenatal medicine最新文献_第10页

The impact of preeclampsia in pregnancy. 先兆子痫对妊娠的影响。

Journal of prenatal medicine Pub Date : 2011-01-01

Aferdita Manaj, Arben Rrugia, Nikita Manoku

{"title":"The impact of preeclampsia in pregnancy.","authors":"Aferdita Manaj, Arben Rrugia, Nikita Manoku","doi":"","DOIUrl":"","url":null,"abstract":"Objective. To observe the influence of preeclampsia during pregnancy. Materials and methods. 5711 patient's records of the year 2008 and 6188 patient's records of the year 2009 of Obstetric/Gynecologic hospital 'Queen Geraldina' have been consulted. The age of women that we studied in 2008 was between 23-35 and in 2009 was be-tween 25-34 years old. We have made a careful diagnose of inducted hypertension of pregnancy and preeclampsia. Results. The incidence of preeclampsia in the population was 4.1% (n =238) in 2008 and 3.1% (n=192) in 2009.The incidence of the cases that developed from preeclampsia to eclampsia were respectively 1.6% (n=4) and 1.5% (n=3) on 2009. Babies which have preeclamptic mothers were preterm in 13% (n=31) of cases, and 14.5% (n=28) of which have severe hypotrophia vs. 10% (n=24) and 11% (n=21) severe hypotrophia in 2009. Babies mortality on the preeclamptic population were respectively 8% (n=19) and 7.8% (n=15). Conclusions. From the survey resulted that patients diagnosed with preeclampsia manifested on a high rate hypertension and proteinuria. Prematurity, severe hypotrophy and baby's mortality were the major complications of preeclampsia. Women with preeclampsia were especially the youngest.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"5 1","pages":"19-22"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279149/pdf/prenatal-05-0019.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30520536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperechogenic fetal bowel: an ultrasonographic marker for adverse fetal and neonatal outcome? 胎儿肠道高回声：胎儿和新生儿不良结局的超声标志物？

Journal of prenatal medicine Pub Date : 2011-01-01

Maria Antonietta De Oronzo

引用次数: 0

Update on systemic lupus erythematosus pregnancy. 妊娠系统性红斑狼疮的最新进展。

Journal of prenatal medicine Pub Date : 2010-10-01

Irene Iozza, Stefano Cianci, Angela Di Natale, Giovanna Garofalo, Anna Maria Giacobbe, Elsa Giorgio, Maria Antonietta De Oronzo, Salvatore Politi

{"title":"Update on systemic lupus erythematosus pregnancy.","authors":"Irene Iozza, Stefano Cianci, Angela Di Natale, Giovanna Garofalo, Anna Maria Giacobbe, Elsa Giorgio, Maria Antonietta De Oronzo, Salvatore Politi","doi":"","DOIUrl":"","url":null,"abstract":"Women with Systemic Lupus Erythematosus (SLE) still face significant risks when embarking on a pregnancy. Improvements in the field of pathophysiology, in diagnosis and a greater number of therapeutic options in the treatment of SLE, have made the medical community regard these patients with less trepidation. Despite these advances, however, the risk of significant morbidity to both the mother and the fetus still exists. THE INTERACTION OF LUPUS AND PREGNANCY IS VERY COMPLEX: the consensus is that pregnancy can worsen the lupus disease process, even if this is not predictable, and pregnancy can mimic the clinical manifestations of lupus, particularly preeclampsia/eclampsia. More specifically, pregnancy is associated in 50 to 60% of cases with a clinical flare manifesting as renalor hematological symptoms. Severe flares are uncommon (10%) and the risk of maternal death is now2 to 3%. The risk of the fetus remains high, however with increased risk of spontaneous fetal wastage and premature births, by 4.8 and 6.8 times, respectively. It is well documented that antiphospholipid syndrome and antiphospholipid antibodies are strongly associated with fetal wastage. Low-dose aspirin orheparin improves fetal outcome in these cases.Timing a pregnancy to coincide with a period of disease quiescence for at least 6 months strongly increases the chances for a healthy and uneventful pregnancy for both mother and baby. Close surveillance, with monitoring of blood pressure, proteinuria and placental blood flow by doppler studies helps the early diagnosis and treatment of complications such as preeclampsia andfoetal distress. Women with SLE frequently need treatment throughout pregnancy based on hydroxychloroquine, lowdose steroids and azathioprine. This update, based on previous available literature, should inform rheumatologists, obstetricians and neonatologists who guide patients in their reproductive decisions.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"4 4","pages":"67-73"},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279186/pdf/prenatal-04-0067.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30520531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parvovirus B19 during pregnancy: a review. 妊娠期细小病毒B19:综述。

Journal of prenatal medicine Pub Date : 2010-10-01

Elsa Giorgio, Maria Antonietta De Oronzo, Irene Iozza, Angela Di Natale, Stefano Cianci, Giovanna Garofalo, Anna Maria Giacobbe, Salvatore Politi

引用次数: 0

Iniencephaly with mediastinal bronchogenic cyst: A case report. 无脑畸形伴纵隔支气管源性囊肿：病例报告

Journal of prenatal medicine Pub Date : 2010-10-01

Yeşim Akdemir, Habibe Ayvacı, Oya Demirci, Davut Sahin, Ersan Demirağ, Hamdullah Sözen, Mehmet Uludoğan

引用次数: 0

Uterine artery Doppler flow studies in obstetric practice. 子宫动脉多普勒血流在产科实践中的研究。

Journal of prenatal medicine Pub Date : 2010-10-01

Rosalba Giordano, Alessandra Cacciatore, Mattea Romano, Beatrice La Rosa, Ilenia Fonti, Roberto Vigna

引用次数: 0

Shoulder dystocia: an Evidence-Based approach. 肩难产：循证方法。

Journal of prenatal medicine Pub Date : 2010-07-01

Salvatore Politi, Laura Dʼemidio, Pietro Cignini, Maurizio Giorlandino, Claudio Giorlandino

{"title":"Shoulder dystocia: an Evidence-Based approach.","authors":"Salvatore Politi, Laura Dʼemidio, Pietro Cignini, Maurizio Giorlandino, Claudio Giorlandino","doi":"","DOIUrl":"","url":null,"abstract":"Shoulder Dystocia (SD) is the nightmare of obstetricians. Despite its low incidence, SD still represents a huge risk of morbidity for both the mother and fetus. Even though several studies showed the existence of both major and minor risk factors that may complicate a delivery, SD remains an unpreventable and unpredictable obstetric emergency. When it occurs, SD is difficult to manage due to the fact that there are not univocal algorithms for its management.Nevertheless, even if it is appropriately managed, SD is one of the most litigated cause in obstetrics, because it is frequently associated with permanent birth-related injuries and mother complications.All the physicians should be prepared to manage this obstetric emergency by attending periodic training, even if SD is difficult to teach for its rare occurrence and because in clinical practice it is often handled by experienced obstetricians.THE PURPOSE OF THIS STUDY IS TO REVIEW THE LITERATURE CONCERNING THE EVERLASTING PROBLEMS OF SD: identification of risk factors for the early detection of delivery at high risk of SD and a systematic management of this terrifying obstetric emergency in order to avoid the subsequent health, medico-legal and economic complications.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"4 3","pages":"35-42"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279180/pdf/prenatal-04-0035.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30521715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of maternal and neonatal outcomes in women with HELLP syndrome and women with severe preeclampsia without HELLP syndrome. HELLP综合征妇女与无HELLP综合征的重度子痫前期妇女孕产妇和新生儿结局的比较

Journal of prenatal medicine Pub Date : 2010-07-01

Abdulkadir Turgut, Oya Demirci, Elif Demirci, Mehmet Uludoğan

{"title":"Comparison of maternal and neonatal outcomes in women with HELLP syndrome and women with severe preeclampsia without HELLP syndrome.","authors":"Abdulkadir Turgut, Oya Demirci, Elif Demirci, Mehmet Uludoğan","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To examine and to compare postpartum maternal and neonatal complications and morbidities in women with HELLP syndrome (HELLP group) and women with severe preeclampsia without HELLP syndrome (severe preeclamptic group).Methods: In this retrospective study, 111 patients in the HELLP group were matched with 467 patients in the severe preeclamptic group according to maternal and neonatal complications and morbidities.Results: The rate of transfusion of blood products and acute renal failure was significantly greater in women with HELLP syndrome. One maternal mortality (0.9 % ) was found in women withHELLP syndrome, and no maternal mortality in women in severe preeclamptic group a. There were significant differences between the HELLP group and the severe preeclamptic group in neonatal mortality and morbidity. It was found that HELLP syndrome cases had significantly lower gestational age and fetal bodyweight. The simultaneous presence of HELLP syndrome and preeclampsia, along with oliguria, ascites, thrombocytopenia, elevated liver enzymes and caesarean delivery, was associated with post-partum complications.Conclusion: This study shows that maternal and neonatal morbidity and mortality are increased in pregnancies complicated by severe preeclampsia with HELLP syndrome. Neonatal mortality and morbidity appear to be influenced primarily by gestational age at delivery.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"4 3","pages":"51-8"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279181/pdf/prenatal-04-0051.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30521718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The use of DHPLC (Denaturing High Performance Liquid Chromatography) in II level screening of the CFTR gene in Prenatal Diagnosis. DHPLC（变性高效液相色谱法）在产前诊断中CFTR基因II级筛选中的应用。

Journal of prenatal medicine Pub Date : 2010-07-01

Alvaro Mesoraca, Manuela Di Natale, Antonella Cima, Gianluca Di Giacomo, Monica Sarti, Maria Antonietta Barone, Domenico Bizzoco, Pietro Cignini, Luisa Mobili, Laura Dʼemidio, Claudio Giorlandino

{"title":"The use of DHPLC (Denaturing High Performance Liquid Chromatography) in II level screening of the CFTR gene in Prenatal Diagnosis.","authors":"Alvaro Mesoraca, Manuela Di Natale, Antonella Cima, Gianluca Di Giacomo, Monica Sarti, Maria Antonietta Barone, Domenico Bizzoco, Pietro Cignini, Luisa Mobili, Laura Dʼemidio, Claudio Giorlandino","doi":"","DOIUrl":"","url":null,"abstract":"Objective: The aim of the study is to evaluate the role of Denaturing High Performance Liquid Chromatography (DHPLC) in the second level screening of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene.Methods: A 9-month prospective study, between June 2008 and March 2009 at Artemisia Fetal Medical Centre, included 3829 samples of amniotic fluid collected from women undergoing mid-trimester amniocentesis.The genetic diagnosis of CF was based on research of the main mutations of the CFTR gene on fetal DNA extracted from the amniocytes, (first level screening) using different commercial diagnostic systems. A second level screening using DHPLC, on the amniotic fluid and on a blood sample from the couple, was offered in case of fetuses heterozygous at first level screening.Results: Of 3829 fetuses, 134 were found to be positive, 129 heterozygous and 5 affected. Of the 129 couples, following appropriate genetic counselling, 53 requested a second level screening. Through the use of DHPLC, 44 couples were found to be negative, and in nine couples, nine rare mutations were identified.Conclusions: The first level screening can be useful to evidence up to 75% of the CF mutations. The second level screening can identify a further 10% of mutant alleles. DHPLC was found to be a reliable and specific method for the rapid identification of the rare CFTR mutations which were not revealed in initial first level screening.","PeriodicalId":89592,"journal":{"name":"Journal of prenatal medicine","volume":"4 3","pages":"45-8"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279182/pdf/prenatal-04-0045.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30521717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonvisualization of fetal gallbladder: a case report and review of the literature. 胎儿胆囊不可见:1例报告及文献复习。

Journal of prenatal medicine Pub Date : 2010-07-01

Annamaria Giacobbe, Elsa Giorgio, Angela Dinatale, Maria Antonietta De Oronzo, Irene Iozza, Giovanna Garofalo, Salvatore Politi

引用次数: 0