Comparison of maternal and neonatal outcomes in women with HELLP syndrome and women with severe preeclampsia without HELLP syndrome.

Journal of prenatal medicine Pub Date : 2010-07-01
Abdulkadir Turgut, Oya Demirci, Elif Demirci, Mehmet Uludoğan
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Abstract

Objective: To examine and to compare postpartum maternal and neonatal complications and morbidities in women with HELLP syndrome (HELLP group) and women with severe preeclampsia without HELLP syndrome (severe preeclamptic group).

Methods: In this retrospective study, 111 patients in the HELLP group were matched with 467 patients in the severe preeclamptic group according to maternal and neonatal complications and morbidities.

Results: The rate of transfusion of blood products and acute renal failure was significantly greater in women with HELLP syndrome. One maternal mortality (0.9 % ) was found in women withHELLP syndrome, and no maternal mortality in women in severe preeclamptic group a. There were significant differences between the HELLP group and the severe preeclamptic group in neonatal mortality and morbidity. It was found that HELLP syndrome cases had significantly lower gestational age and fetal bodyweight. The simultaneous presence of HELLP syndrome and preeclampsia, along with oliguria, ascites, thrombocytopenia, elevated liver enzymes and caesarean delivery, was associated with post-partum complications.

Conclusion: This study shows that maternal and neonatal morbidity and mortality are increased in pregnancies complicated by severe preeclampsia with HELLP syndrome. Neonatal mortality and morbidity appear to be influenced primarily by gestational age at delivery.

HELLP综合征妇女与无HELLP综合征的重度子痫前期妇女孕产妇和新生儿结局的比较
目的:探讨并比较HELLP综合征妇女(HELLP组)和无HELLP综合征的重度子痫前期妇女(重度子痫前期组)产后母婴并发症及发病率。方法:回顾性分析111例HELLP组患者与467例重度先兆子痫组患者根据母婴并发症及发病情况进行配对。结果:女性HELLP综合征患者输血及急性肾功能衰竭发生率显著增高。在HELLP综合征妇女中发现1例产妇死亡率(0.9%),而在重度子痫前期a组妇女中没有产妇死亡率。HELLP组和重度子痫前期a组在新生儿死亡率和发病率上有显著差异。发现HELLP综合征患者的胎龄和胎体质量明显降低。同时出现HELLP综合征和先兆子痫,以及少尿、腹水、血小板减少、肝酶升高和剖腹产,与产后并发症有关。结论:本研究表明妊娠合并重度子痫前期伴HELLP综合征的产妇和新生儿发病率和死亡率增高。新生儿死亡率和发病率似乎主要受分娩时胎龄的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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