Two cases of complete hydatidiform mole and coexistent live fetus.

Journal of prenatal medicine Pub Date : 2013-01-01
Antonella Vimercati, Alessandra Caterina de Gennaro, Isabella Cobuzzi, Silvana Grasso, Marinella Abruzzese, Fabiana Divina Fascilla, Gennaro Cormio, Luigi Selvaggi
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Abstract

The aim of this study was to report the clinical features, management, and outcome of complete hydatidiform mole with a coexisting viable fetus. Two cases are reported. In both cases ultrasound examination demonstrated a normally growing live fetus alongside a normal placenta and an additional intrauterine echogenic mass with features of hydatidiform mole. The hCG levels were significantly increased and fetal karyotypes were normal. A cesarean section performed at 28 weeks' gestation in the first case and at 26 weeks' gestation in the second one resulted in the delivery of live normal infant and two adjoining placentas in both cases. Microscopic examination of the abnormal placentas confirmed complete hydatidiform mole. The babies did well and serial maternal serum hCG levels showed a declining trend and were undetectable by a few months after delivery. Continuation of a twin pregnancy with complete hydatidiform mole (CHMF) is an acceptable option. There is, although, an increased risk of developing maternal and fetal complications. Close surveillance of an ongoing pregnancy is compulsory to detect potential early signs of complications.

完整葡萄胎2例,活胎共存。
本研究的目的是报道完全葡萄胎与共存存活胎儿的临床特征、处理和结局。报告了两例。这两例超声检查均显示正常生长的活胎儿,伴有正常胎盘和子宫内超声肿块,伴有葡萄胎的特征。hCG水平明显升高,胎儿核型正常。在第一例妊娠28周和第二例妊娠26周时分别进行了剖宫产手术,结果两例均分娩出正常的活婴和两个相邻的胎盘。显微镜检查异常胎盘证实完全葡萄胎。婴儿表现良好,连续母亲血清hCG水平呈下降趋势,分娩后几个月无法检测到。继续双胎妊娠完全葡萄胎(CHMF)是一个可接受的选择。不过,孕妇和胎儿出现并发症的风险会增加。密切监测正在进行的妊娠是必要的,以发现潜在的并发症的早期迹象。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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