Bioelectromagnetics最新文献

Extremely low-frequency electromagnetic fields targeting spleen modifies the populations of immunocytes in the spleen

IF 1.8 3区生物学

Bioelectromagnetics Pub Date : 2024-12-17 DOI: 10.1002/bem.22532

Sijia Chen PhD, Wei Wei PhD, Ziang Wang MSc, Jiazhen Zhu MSc, Hailong Zhang PhD, Guihu Wang PhD, Ni Guo MSc, Jun Li PhD, Yanhua Mu PhD, Naming Zhang PhD, Zongfang Li PhD

{"title":"Extremely low-frequency electromagnetic fields targeting spleen modifies the populations of immunocytes in the spleen","authors":"Sijia Chen PhD, Wei Wei PhD, Ziang Wang MSc, Jiazhen Zhu MSc, Hailong Zhang PhD, Guihu Wang PhD, Ni Guo MSc, Jun Li PhD, Yanhua Mu PhD, Naming Zhang PhD, Zongfang Li PhD","doi":"10.1002/bem.22532","DOIUrl":"10.1002/bem.22532","url":null,"abstract":"Our study focused on investigating the bioeffects of extremely low-frequency electromagnetic fields (ELF-EMFs) on the immune function of the spleen. We designed an electromagnetic instrument that can locally target on spleen, the spleens of mice were locally exposed to the ELF-EMF (50 Hz, 30 mT) for 14 days (4 h/day). Parallelly, the isolated splenic T cells were exposed to ELF-EMF (50 Hz, 15 mT) for 2 h. After the exposure, the splenocyte showed a reduced apoptosis rate. Among the splenocytes, the CD4+ T cells and natural killer cells accumulated, the percentage of B cells decreased. In vitro study demonstrated that ELF-EMF induced the alteration of T cell subsets, showing an increased percentage of CD4+ T cells and a decreased percentage of CD8+ T cells. Within CD4+ T cells, the population of T helper (Th) 17 cells increased, and the population of regulatory T cells (Treg) cells decreased. The enrichment of the nuclear factor (NF)-κB pathway in the splenic T cells was found to be reduced after exposure to ELF-EMF. Our findings suggest that ELF-EMF regulated the immune function of the spleen by changing the proportion of immune cells in the spleen. Specifically, the differentiation of spleen T cells was induced by ELF-EMF toward Th17 cells and inhibited by ELF-EMF into Treg cells. The NF-κB signaling pathway probably accounts for the effects of ELF-EMF on the spleen T cells.","PeriodicalId":8956,"journal":{"name":"Bioelectromagnetics","volume":"46 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bem.22532","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Platycodon grandiflorum seeds exposure to static magnetic field on germination and early seedling growth

IF 1.8 3区生物学

Bioelectromagnetics Pub Date : 2024-12-15 DOI: 10.1002/bem.22530

Xingxing Yang PhD, Xin Wang, Xuhan Zhang, Jinlan Hu, Jing Wang, Yansong Chen PhD, Yong Zhu PhD

{"title":"Effects of Platycodon grandiflorum seeds exposure to static magnetic field on germination and early seedling growth","authors":"Xingxing Yang PhD, Xin Wang, Xuhan Zhang, Jinlan Hu, Jing Wang, Yansong Chen PhD, Yong Zhu PhD","doi":"10.1002/bem.22530","DOIUrl":"10.1002/bem.22530","url":null,"abstract":"Effects of non-uniform upward (north) and downward (south) 300 mT static magnetic field (SMF) 14 days (24 h/day) treatment of Platycodon grandiflorum seeds on germination, seedling growth, enzyme activities, malondialdehyde (MDA) level and seedling chlorophyll content were investigated under laboratory conditions. Germination rate, index and potential from magnetically exposed Anhui and Hebei Platycodon grandiflorum seeds were significantly not affected (p > 0.05), however, the values of these germination variables were notably higher in Anhui Platycodon grandiflorum seeds than Hebei seeds. Treatment of Hebei Platycodon grandiflorum seeds with 300 mT SMFs increased (p < 0.05) the catalase (CAT), superoxide dismutase (SOD), α-and β-amylase activities and chlorophyll content significantly, the root length and MDA level of Anhui seeds were reduced, while the MDA level was had no obviously affect. The results suggest that non-uniform upward 300 mT SMF had potential to active the antioxidant enzymes (catalase and superoxide dismutase) and hydrolytic enzymes (α-and β-amylase activities) and increase the chlorophyll content of Platycodon grandiflorus seeds under laboratory conditions.","PeriodicalId":8956,"journal":{"name":"Bioelectromagnetics","volume":"46 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of mobile phone electromagnetic fields on the human resting state wake EEG and event-related potential: A systematic review and meta-analysis 手机电磁场对人体静息唤醒脑电图和事件相关电位的影响：系统回顾和荟萃分析。

IF 1.8 3区生物学

Bioelectromagnetics Pub Date : 2024-11-22 DOI: 10.1002/bem.22531

Anna C. Prins BSc, Koen Baas PhD, Johan N. van der Meer PhD, Marc Jacobs PhD, Aart J. Nederveen PhD

{"title":"The effect of mobile phone electromagnetic fields on the human resting state wake EEG and event-related potential: A systematic review and meta-analysis","authors":"Anna C. Prins BSc, Koen Baas PhD, Johan N. van der Meer PhD, Marc Jacobs PhD, Aart J. Nederveen PhD","doi":"10.1002/bem.22531","DOIUrl":"10.1002/bem.22531","url":null,"abstract":"The rapid growth of mobile phone usage and its use of radiofrequency electromagnetic fields (RF-EMF) have raised concerns about potential health risks. Researchers have conducted studies to examine the effects of RF-EMF on the brain using electroencephalography (EEG). We conducted a systematic quality assessment and meta-analysis of published research in this field to establish high-quality studies as references for future protocols. The electronic search yielded 244 records from which a total of 51 studies were included in the review after excluding studies based on study design, and data or report availability. Of these 51 studies, 31 (61%) focused on resting state wake EEG and 20 (39%) on event-related potentials (ERP). None of the 51 studies were free from risk of bias. From the 51 included studies, we were able to use seven studies to create three different groups for meta-analysis for resting state wake EEG and five studies to create 10 different groups for meta-analysis for ERP. Per group the number of studies varies from 1 to 5. Our procedure is the first systematic quality assessment in this field and revealed three important findings. First, there is evidence of an effect on the EEG of a 2G protocol using an eyes-open condition. Second, we did not find evidence for EEG effects during task performance. This suggests that the impact of EMF during task performance is less pronounced compared to the resting state condition. Third, this meta-analysis shows that the field is unable to create an evidence base for most comparisons due to heterogeneity. We therefore advise that all future studies are double-blind in nature, adhere to the methodological standard of randomized experiments, and publish their protocols first.","PeriodicalId":8956,"journal":{"name":"Bioelectromagnetics","volume":"46 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bem.22531","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142685926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Numerical and analytical inspection of magnetic field effects in the radical pair mechanism by a simplified rate equation model 通过简化速率方程模型对自由基对机制中的磁场效应进行数值和分析检验。

IF 1.8 3区生物学

Bioelectromagnetics Pub Date : 2024-11-04 DOI: 10.1002/bem.22528

Andreas Deser, Jens Kuhne, Heinrich A. M. Leymann

引用次数: 0

Action potential threshold variability for different electrostimulation models and its potential impact on occupational exposure limit values 不同电刺激模型的动作电位阈值变化及其对职业接触限值的潜在影响。

IF 1.8 3区生物学

Bioelectromagnetics Pub Date : 2024-11-03 DOI: 10.1002/bem.22529

Florian Soyka, Thomas Tarnaud, Carsten Alteköster, Ruben Schoeters PhD, Tom Plovie MSc, Wout Joseph, Emmeric Tanghe

{"title":"Action potential threshold variability for different electrostimulation models and its potential impact on occupational exposure limit values","authors":"Florian Soyka, Thomas Tarnaud, Carsten Alteköster, Ruben Schoeters PhD, Tom Plovie MSc, Wout Joseph, Emmeric Tanghe","doi":"10.1002/bem.22529","DOIUrl":"10.1002/bem.22529","url":null,"abstract":"Occupational exposure limit values (ELVs) for body internal electric fields can be derived from thresholds for action potential generation. These thresholds can be calculated with electrostimulation models. The spatially extended nonlinear node model (SENN) is often used to determine such thresholds. Important parameters of these models are the membrane channel dynamics describing the ionic transmembrane currents as well as the temperature at which the models operate. This work compares action potential thresholds for five different membrane channel dynamics used with the SENN model. Furthermore, two more detailed double-cable models by Gaines et al. (MRG-Sensory and MRG-Motor) are also considered in this work. Thresholds calculated with the SENN model and the MRG models are compared for frequencies between 1 Hz and 100 kHz and temperatures at 22°C and 37°C. Results show that MRG thresholds are lower than SENN thresholds. Deriving alternative ELVs from these thresholds shows that the alternative ELVs can change significantly with different ion channel dynamics (up to a factor of 22). Using the double cable model could lead to approximately ten times lower alternative exposure limit values. On the contrary, using the SENN model with different membrane channel dynamics could also lead to higher alternative exposure limit values. Therefore, future exposure guidelines should take the influence of different electrostimulation models into account when deriving ELVs.","PeriodicalId":8956,"journal":{"name":"Bioelectromagnetics","volume":"46 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bem.22529","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The influence of eyelashes on electric field distribution and absorbed power density in the cornea under millimeter-wave exposure 睫毛对毫米波照射下角膜电场分布和吸收功率密度的影响

IF 1.8 3区生物学

Bioelectromagnetics Pub Date : 2024-10-14 DOI: 10.1002/bem.22526

Negin Foroughimehr PhD, Zoltan Vilagosh PhD, Ali Yavari PhD, Andrew Wood PhD

{"title":"The influence of eyelashes on electric field distribution and absorbed power density in the cornea under millimeter-wave exposure","authors":"Negin Foroughimehr PhD, Zoltan Vilagosh PhD, Ali Yavari PhD, Andrew Wood PhD","doi":"10.1002/bem.22526","DOIUrl":"10.1002/bem.22526","url":null,"abstract":"As millimeter wave (MMW) technology, particularly in fifth-generation (5G) devices, gains prominence, there is a crucial need for comprehensive electromagnetic (EM) models of ocular tissues to understand and characterize EM exposure conditions accurately. This study employs numerical modeling to investigate the interaction between MMW and the cornea, aiming to characterize EM field distributions and absorption within an anatomically accurate eye model while considering the influence of eyelashes. Using the finite-difference time-domain (FDTD) method, we conduct simulations of EM radiation interactions from 20.0 to 100.0 GHz with a human eye model. Moreover, we analyze the temperature distribution increase within the eye model using a thermal sensor in XFdtd, employing a scheme based on the finite difference (FD) method. Our findings reveal a nonuniform distribution of the EM field, particularly intensified in corneal regions adjacent to eyelashes and eyelids. Despite similar EM field patterns, the presence or absence of eyelashes has minimal impact on temperature differences. However, the study highlights increased radiation absorption by the eyelid's epidermis at 100.0 GHz, reducing the rise in the cornea's temperature.","PeriodicalId":8956,"journal":{"name":"Bioelectromagnetics","volume":"45 8","pages":"375-386"},"PeriodicalIF":1.8,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bem.22526","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142457202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterising core body temperature response of free-moving C57BL/6 mice to 1.95 GHz whole-body radiofrequency-electromagnetic fields 自由移动的 C57BL/6 小鼠对 1.95 GHz 全身射频电磁场的核心体温反应特征。

IF 1.8 3区生物学

Bioelectromagnetics Pub Date : 2024-10-14 DOI: 10.1002/bem.22527

Emma Sylvester BMedHlthSc (Hons), Chao Deng PhD, Robert McIntosh PhD, Steve Iskra PhD, John Frankland BComp (Hons), Raymond McKenzie BAppSc (Phys) (Hons), Rodney J. Croft PhD

{"title":"Characterising core body temperature response of free-moving C57BL/6 mice to 1.95 GHz whole-body radiofrequency-electromagnetic fields","authors":"Emma Sylvester BMedHlthSc (Hons), Chao Deng PhD, Robert McIntosh PhD, Steve Iskra PhD, John Frankland BComp (Hons), Raymond McKenzie BAppSc (Phys) (Hons), Rodney J. Croft PhD","doi":"10.1002/bem.22527","DOIUrl":"10.1002/bem.22527","url":null,"abstract":"The present study investigated the core body temperature (CBT) response of free-moving adult male and female C57BL/6 mice, during and following a 2-h exposure to 1.95 GHz RF-EMF within custom-built reverberation chambers, using temperature capsules implanted within the intraperitoneal cavity and data continuously logged and transmitted via radiotelemetry postexposure. Comparing RF-EMF exposures (WBA-SAR of 1.25, 2.5, 3.75, and 5 W/kg) to the sham-exposed condition, we identified a peak in CBT within the first 16 min of RF-EMF exposure (+0.15, +0.31, +0.24, +0.37°C at 1.25, 2.5, 3.75, and 5 W/kg respectively; statistically significant at WBA-SAR ≥ 2.5 W/kg only), which largely dissipated for the remainder of the exposure period. Immediately before the end of exposure, only the CBT of the 5 W/kg condition was statistically differentiable from sham. Based on our findings, it is apparent that mice are able to effectively compensate for the increased thermal load at RF-EMF strengths up to 5 W/kg. In addition, the elevated CBT at the end of the exposure period in the 5 W/kg condition was statistically significantly reduced compared to the sham condition immediately after RF-EMF exposure ceased. This would indicate that measures of CBT following the end of an RF-EMF exposure period may not reflect the actual change in the CBT of mice caused by RF-EMF exposure in mice.","PeriodicalId":8956,"journal":{"name":"Bioelectromagnetics","volume":"45 8","pages":"387-398"},"PeriodicalIF":1.8,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bem.22527","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142457201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective effect of radiofrequency exposure against menadione-induced oxidative DNA damage in human neuroblastoma cells: The role of exposure duration and investigation on key molecular targets 射频照射对人类神经母细胞瘤细胞中由甲萘醌诱导的 DNA 氧化损伤的保护作用：暴露持续时间的作用和对关键分子靶点的研究

IF 1.8 3区生物学

Bioelectromagnetics Pub Date : 2024-09-24 DOI: 10.1002/bem.22524

Anna Sannino PhD, Mariateresa Allocca PhD, Maria R. Scarfì MSc, Stefania Romeo PhD, Olga Zeni PhD

{"title":"Protective effect of radiofrequency exposure against menadione-induced oxidative DNA damage in human neuroblastoma cells: The role of exposure duration and investigation on key molecular targets","authors":"Anna Sannino PhD, Mariateresa Allocca PhD, Maria R. Scarfì MSc, Stefania Romeo PhD, Olga Zeni PhD","doi":"10.1002/bem.22524","DOIUrl":"10.1002/bem.22524","url":null,"abstract":"In our previous studies, we demonstrated that 20 h pre-exposure of SH-SY5Y human neuroblastoma cells to 1950 MHz, UMTS signal, at specific absorption rate of 0.3 and 1.25 W/kg, was able to reduce the oxidative DNA damage induced by a subsequent treatment with menadione in the alkaline comet assay while not inducing genotoxicity per se. In this study, the same cell model was used to test the same experimental conditions by setting different radiofrequency exposure duration and timing along the 72 h culture period. The results obtained in at least three independent experiments indicate that shorter exposure durations than 20 h, that is, 10, 3, and 1 h per day for 3 days, were still capable to exert the protective effect while not inducing DNA damage per se. In addition, to provide some hints into the mechanisms underpinning the observed phenomenon, thioredoxin-1, heat shock transcription factor 1, heat shock protein 70, and poly [ADP-ribose] polymerase 1, as key molecular players involved in the cellular stress response, were tested following 3 h of radiofrequency exposure in western blot and qRT-PCR experiments. No effect resulted from molecular analysis under the experimental conditions adopted.","PeriodicalId":8956,"journal":{"name":"Bioelectromagnetics","volume":"45 8","pages":"365-374"},"PeriodicalIF":1.8,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bem.22524","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulsed electromagnetic fields attenuate human musculocutaneous nerve damage induced by biceps eccentric contractions 脉冲电磁场可减轻肱二头肌偏心收缩引起的人体肌皮神经损伤。

IF 1.8 3区生物学

Bioelectromagnetics Pub Date : 2024-09-24 DOI: 10.1002/bem.22525

Karina Kouzaki PhD, Koichi Nakazato PhD

引用次数: 0

A comparative study of simulated electric fields of transcranial magnetic stimulation targeting different cortical motor regions 针对不同皮层运动区的经颅磁刺激模拟电场比较研究

IF 1.8 3区生物学

Bioelectromagnetics Pub Date : 2024-09-16 DOI: 10.1002/bem.22523

Jack Jiaqi Zhang PhD, Bella Bingbing Zhang MSc, Zhongfei Bai PhD, Kenneth N. K. Fong PhD

引用次数: 0