Blood Pressure Monitoring最新文献

{"title":"Combination of treatment intensity score and interankle diastolic blood pressure is associated with cardiovascular prognosis among adults with controlled hypertension who have pre-existing cardiovascular disease.","authors":"Zhe Zhang, Zeyuan Fan, Limin Han","doi":"10.1097/MBP.0000000000000775","DOIUrl":"https://doi.org/10.1097/MBP.0000000000000775","url":null,"abstract":"<p><strong>Background: </strong>Despite adequate blood pressure control, many hypertensive patients remain at risk of cardiocerebral events. This study investigated the relationship between antihypertensive treatment intensity score (TIS) and interankle diastolic blood pressure difference (dIAND), and their utility in risk stratification.</p><p><strong>Methods: </strong>We analyzed 368 patients with well-controlled hypertension (24-hour ambulatory blood pressure monitoring ≤ 130/80 mmHg), and pre-existing cardiovascular disease. Patients were stratified by median TIS (0.625) into low (TIS1) and high (TIS2) intensity groups. dIAND was calculated as the absolute difference in diastolic pressure between ankles. Patients were followed for 3 years for adverse cardiocerebral events.</p><p><strong>Results: </strong>During follow-up (median 36 months), 73 major events were documented. The high TIS group exhibited significantly higher event rates (25.8 vs. 14.6%, log-rank P = 0.021), and remained an independent predictor after multivariable adjustment [adjusted hazard ratio: 1.92, 95% confidence interval (CI): 1.07-3.45, P = 0.027]. A modest correlation was observed between TIS and dIAND (r = 0.26, P < 0.001). Patients with dIAND ≥15 mmHg had higher event rates (35.0 vs. 18.0%; P = 0.015); this association was attenuated in multivariable models. Notably, the combination of high TIS and elevated dIAND identified a subgroup with a 3.22-fold increased risk (adjusted hazard ratio: 3.22, 95% CI: 1.51-6.85, P = 0.002) compared with the reference group (TIS ≤ 0.625 and dIAND < 15 mmHg).</p><p><strong>Conclusion: </strong>TIS independently predicts cardiocerebral risk and correlates with dIAND. The combined assessment may refine risk stratification in controlled hypertension, offering a practical approach to identify high-risk patients requiring intensified management.</p>","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the BTL ambulatory blood pressure monitoring NG ambulatory blood pressure monitoring device according to the Universal Standard International Organization for Standardization 81060-2:2018.","authors":"Jan David, Xenie Budinska, Sarka Peskova, Radka Adamkova","doi":"10.1097/MBP.0000000000000776","DOIUrl":"https://doi.org/10.1097/MBP.0000000000000776","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to validate the BTL ambulatory blood pressure monitoring NG ambulatory blood pressure (BP) monitoring device in a general population, including children aged 4-12 years, according to the International Organization for Standardization 81060-2:2018 standard with amendments A1:2020 and A2:2024.</p><p><strong>Methods: </strong>The study included both clinical and ambulatory validation. In the clinical part, 85 participants (50 adults and 35 children) underwent same-arm sequential measurements with alternating test device and reference readings. The ambulatory part involved 35 adults tested using a dynamic protocol on a bicycle ergometer with at least a 15% heart rate increase. All procedures strictly followed standard requirements, including arm circumference and BP distributions.</p><p><strong>Results: </strong>The device met all validation criteria defined by the standard. In clinical testing, mean differences were -0.52 mmHg systolic and -0.39 mmHg diastolic, with standard deviations of 4.44 and 4.17 mmHg. All cuff subgroups also met criterion 1, and criterion 2 was fulfilled with standard deviations of 3.80 mmHg systolic and 3.35 mmHg diastolic, including the children subgroup. In the ambulatory validation, mean differences were -0.40 mmHg systolic and -0.50 mmHg diastolic, with standard deviations of 5.88 and 5.05 mmHg.</p><p><strong>Conclusion: </strong>To our knowledge, this is the first published validation of an ambulatory BP monitoring device that fully followed the unified 81060-2:2018 standard, including amendments A1:2020 and A2:2024. The device fulfilled all clinical and ambulatory validation criteria across all required distributions and age groups, including children.</p>","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validating the accuracy of Omron HBP-1320 electronic blood pressure monitor in pediatric and adult populations according to Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (ISO 81060-2:2018/Amd 1:2020).","authors":"Li Qin, Jie Dong, Hong Jiang, Ya Sun, Jiayi Zhai, Yaya Xue, Ming Liu, Fulai Shen, Yicheng Qiu, Jianhui Xie, Wuquan Huang","doi":"10.1097/MBP.0000000000000774","DOIUrl":"https://doi.org/10.1097/MBP.0000000000000774","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the accuracy of the Omron HBP-1320 electronic blood pressure (BP) monitor for ambulatory BP measurement in both pediatric and adult populations according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) (ISO 81060-2:2018/Amd 1:2020) protocol.</p><p><strong>Methods: </strong>Subjects who met age, gender, BP, and cuff distribution criteria specified by the AAMI/ESH/ISO (ISO 81060-2:2018/Amd1:2020) protocol were recruited for this study. BP measurements were performed using the same-arm sequential measurement method. The test device was equipped with cuffs suitable for arm circumferences ranging from 12.0 to 42.0 cm.</p><p><strong>Results: </strong>A total of 87 participants were initially recruited, with 85 (35 children and 50 adults) included in the final analysis after excluding two participants. The mean age of all participants was 38.1 ± 28.98 years, with children averaging 6.7 ± 2.23 years and adults 60.1 ± 15.39 years. For validation criterion 1, the mean ± SD of differences between the test device and reference BP measurements was 2.3 ± 5.47 mmHg for SBP and 1.3 ± 5.65 mmHg for DBP. Both mean differences were ≤5 mmHg, and SDs ≤ 8 mmHg, meeting the criterion. For validation criterion 2, the mean differences were 2.3 ± 3.93 mmHg for SBP and 1.3 ± 5.13 mmHg for DBP, satisfying the thresholds of ≤6.55 mmHg for SBP and ≤6.82 mmHg for DBP.</p><p><strong>Conclusion: </strong>The Omron HBP-1320 electronic BP monitor meets the requirements of the AAMI/ESH/ISO (ISO 81060-2:2018/Amd 1:2020) validation standard for adults and children.</p>","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of phenotypic age acceleration with the risk of all-cause and cardiovascular disease-related mortality in patients with hypertension.","authors":"Qiao Yu, Baoling Shang, Haijiao Sun, Wei Jiang, Qian Cao, Xu Zou","doi":"10.1097/MBP.0000000000000766","DOIUrl":"10.1097/MBP.0000000000000766","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the associations between phenotypic age acceleration (PhenoAgeAccel) and all-cause/cardiovascular disease (CVD)-related mortality in hypertensive patients.</p><p><strong>Methods: </strong>We analyzed data from 14 352 hypertensive adults (≥20 years) in the National Health and Nutrition Examination Survey 1999-2010. PhenoAge was calculated using chronological age and nine biomarkers (albumin, creatinine, glucose, C-reactive protein, lymphocyte%, mean cell volume, red blood cell distribution width, alkaline phosphatase, and white blood cell count). PhenoAgeAccel was derived as residuals from linear regression of PhenoAge on chronological age. Participants were stratified by PhenoAge [<46.6792 (792-64.774 (T1-T2), ≥64.774 (≥T2)] and PhenoAgeAccel [<-4.3382 (382-0.9896 (T1-T2), ≥0.9896 (≥T2)] tertiles. Cox proportional hazards models assessed mortality risks.</p><p><strong>Results: </strong>Increased all-cause mortality was observed in hypertensive patients with PhenoAge in T1-T2 group [hazards ratio = 4.38, 95% confidence interval (CI): 3.79-5.06] and greater than or equal to T2 (hazards ratio = 14.22, 95% CI: 12.32-16.43). Significant association between PhenoAgeAccel greater than or equal to T2 and increased risk of all-cause mortality in hypertensive patients (hazards ratio = 1.41, 95% CI: 1.29-1.55) was identified. PhenoAge of T1-T2 (hazards ratio = 5.15, 95% CI: 3.86-6.86) and greater than or equal to T2 (hazards ratio = 20.20, 95% CI: 14.98-27.26) were related to increased CVD-related mortality in hypertensive patients. Increased risk of CVD-related mortality was identified in hypertensive patients with PhenoAgeAccel greater than or equal to T2 (hazards ratio = 1.35, 95% CI: 1.17-1.56).</p><p><strong>Conclusion: </strong>Elevated PhenoAge and PhenoAgeAccel significantly predict higher all-cause and CVD mortality in hypertension, supporting clinical risk stratification.</p>","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":" ","pages":"222-233"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144783417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Omron J7136 and HEM-7361T blood pressure monitors according to the International Organization for Standardization protocol (ISO 81060-2:2018 + Amd.1:2020).","authors":"Yi Zhou, Xin-Yu Wang, Yi Zhou, Yan Li, Ji-Guang Wang","doi":"10.1097/MBP.0000000000000756","DOIUrl":"10.1097/MBP.0000000000000756","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the accuracy of OMRON J7136 and HEM-7361T oscillometric blood pressure (BP) monitors in the general population according to the International Organization for Standardization (ISO) 81060-2:2018 and amendment (Amd) 1:2020 standard.</p><p><strong>Method: </strong>Subjects were recruited to fulfill the age, gender, BP, and cuff distributions of the ISO Universal Standard in the general population using the same arm sequential BP measurement method. Three cuffs of the OMRON J7136 were used for arm circumference 17-22 cm (small), 22-32 cm (medium), and 32-42 cm (large). A single cuff 17-36 cm was used on the OMRON HEM-7361T.</p><p><strong>Results: </strong>The mean ± SD of the differences between the OMRON J7136 and reference BP readings was -2.14 ± 6.45/-1.43 ± 5.88 mmHg (systolic/diastolic) for criterion 1. The SD of the average BP differences between the OMRON J7136 and reference BP per subject was 5.49/5.36 mmHg (systolic/diastolic) for criterion 2. For the study on the OMRON HEM-7361T, the corresponding values were -2.56 ± 6.35/-3.18 ± 5.67 mmHg (systolic/diastolic) for criterion 1 and 5.33/5.32 mmHg (systolic/diastolic) for criterion 2.</p><p><strong>Conclusion: </strong>The OMRON J7136 and HEM-7361T BP monitors both fulfilled the requirements of the ISO Universal Standard (ISO 81060-2:2018/AMD 1:2020) in the general population and can be recommended for self-measurement in adults.</p>","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":" ","pages":"236-242"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The possible role of disrupted circadian blood pressure rhythm and excess early morning blood pressure surge in the prediction of future hypertension and hypertension-related target organ damage in patients with a high normal blood pressure profile.","authors":"Cemal Köseoğlu, Can Ramazan Öncel, Ali Çoner","doi":"10.1097/MBP.0000000000000761","DOIUrl":"10.1097/MBP.0000000000000761","url":null,"abstract":"","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":"30 5","pages":"243-244"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144941397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antihypertensive treatment of a patient with normal blood pressure: case report and call for paying attention.","authors":"Hasan Atmaca, Mustafa Kemal Erol, Ertan Yetkin","doi":"10.1097/MBP.0000000000000758","DOIUrl":"10.1097/MBP.0000000000000758","url":null,"abstract":"<p><p>The current 2024 European Society of Cardiology (ESC) guideline for the management of elevated blood pressure and hypertension defines blood pressure less than 115/65 mmHg by ambulatory blood pressure monitoring (ABPM) as nonelevated, blood pressures in-between 115-129 and 65-79 mmHg as elevated blood pressure, and hypertension as ≥130/80 mmHg. There, might be patients seeking medical attention for the symptoms, apparently nonspecific but suggestive of hypertension with optimal, or not elevated, or elevated blood pressure values. A female patient with complaints of headache and dizziness lasting for 2 months has been evaluated in cardiology outpatient clinic and assessed by ABPM. It has been told that she had previously blood pressure of 90-100/50-60 mmHg and was suffering from headache when systolic blood pressure exceeds 110 mmHg. Her 24-h ABPM revealed systolic and diastolic blood pressure as 106/63 mmHg showing nighttime decrease compared with daytime pressures (98/59 mmHg and 108/68 mmHg, respectively). Thereafter, she was instructed to keep continuing the life-style modification and given to beta-blocker (bisoprolol 5 mg) as an antihypertensive treatment. At the end of the 2 weeks of follow-up period, she was headache-free and was feeling comfortable and well with a mean home blood pressure of 98/56 mmHg. We have presented prosperous antihypertensive treatment of a female patient suffering from headache and dizziness with a numerically normal or nonelevated blood pressure. In the presence of symptoms and having not elevated or elevated blood pressure levels, patients' history on previous measure of blood pressure might facilitate our decision-making process.</p>","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":" ","pages":"234-235"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to: 'The possible role of disrupted circadian blood pressure rhythm and excess early morning blood pressure surge in the prediction of future hypertension and hypertension-related target organ damage in patients with a high normal blood pressure profile'.","authors":"Theodoros Kalos, Kyriakos Dimitriadis, Nikolaos Pyrpyris, Konstantinos Tsioufis","doi":"10.1097/MBP.0000000000000763","DOIUrl":"10.1097/MBP.0000000000000763","url":null,"abstract":"","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":"30 5","pages":"245"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144941450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal duration and number of readings for unattended automated office blood pressure measurements in patients with type 2 diabetes.","authors":"Kasper F Struksnes, Jacob V Stidsen, Jens S Nielsen, Michael H Olsen, Thomas B Olesen","doi":"10.1097/MBP.0000000000000764","DOIUrl":"10.1097/MBP.0000000000000764","url":null,"abstract":"<p><strong>Objective: </strong>Unobserved automated office blood pressure (uAOBP) measurement is better correlated to daytime ambulatory blood pressure monitoring (dABPM) than traditional office blood pressure (BP) measurements. However, prolonged uAOBP duration may underestimate BP levels. We aimed to determine the duration of uAOBP that has the lowest proportion of white-coat hypertension (WCH) or masked hypertension (MH) compared with the gold-standard using dABPM in patients with type 2 diabetes (T2DM). Additionally, we examined variables associated with discrepancy between uAOBP and dABPM.</p><p><strong>Methods: </strong>A total of 135 patients with T2DM underwent dABPM as well as uAOBP. uAOBP recordings were taken in the sitting position without prior rest for 24 min at 3-min intervals. Hypertension was defined as blood pressure ≥135/85 mmHg. Multiple uAOBP measurement intervals were compared with dABPM by the proportions of patients with WCH, MH, or consistent classification.</p><p><strong>Results: </strong>Participants had a mean age of 57.7 years, 38% were female, and 66% used antihypertensive drugs. Average dABPM was 126.9/79.5 mmHg. Extension of uAOBP measurements from 3 to 24 min reduced the proportion with WCH significantly (20.7 vs. 27.4%, P  = 0.012), with an identical proportion of MH (4.4 vs. 3.7%). Higher BMI, higher urine albumin-creatinine ratio, and higher education were associated with MH, while WCH was associated with older age and early retirement.</p><p><strong>Conclusion: </strong>Extending the duration of uAOBP measurements from 3 to 24 min in patients with T2DM increased the proportion of patients with consistent classification by reducing WCH without increasing MH, but clinically relevant individual differences between uAOBP measurements and dABPM remained.</p>","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":" ","pages":"214-221"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144783424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of visit-to-visit variability in systolic blood pressure over 5 years and imperceptible atrial conduction: assessment by P-wave signal-averaged electrocardiography.","authors":"Shinichiro Tanaka, Toshiyuki Noda, Tomonori Segawa, Makoto Iwama, Hiroto Yagasaki, Takahiro Ueno, Taro Minagawa, Shinya Minatoguchi","doi":"10.1097/MBP.0000000000000757","DOIUrl":"10.1097/MBP.0000000000000757","url":null,"abstract":"<p><strong>Objective: </strong>Visit-to-visit variability in SBP (VVV-SBP) is associated with increased cardiac events, including atrial fibrillation (AF). P-wave signal-averaged electrocardiography (P-SAECG) detects subtle atrial conduction abnormalities such as atrial late potential (ALP). This study examined the association between VVV-SBP and atrial conduction.</p><p><strong>Methods: </strong>A total of 128 male participants (mean age: 50.8 ± 10.3 years) with normal cardiac function underwent annual blood pressure measurements over 5 years. VVV-SBP was assessed using both the SD and the coefficient of variation (CV) of SBP, calculated from five BP measurements taken annually during the 5 years prior to the P-SAECG. P-SAECG parameters included the filtered P-wave duration (FPD) and the root-mean-square voltage of the last 20 ms of the P-wave (RMS20). ALP positivity was defined as FPD > 120 ms and RMS20 < 3.5 µV.</p><p><strong>Results: </strong>ALP positivity was observed in 33 participants (25.8%). SD-SBP was higher in the ALP-positive group (9.59 ± 4.15 vs. 7.92 ± 3.66 mmHg; P  = 0.031). This trend was seen in CV-SBP (ALP-positive; 0.077 ± 0.031 vs. ALP-negative; 0.064 ± 0.027; P  = 0.022). ALP positivity was significantly less frequent in the lowest quartile and more frequent in the highest quartile of both SD-SBP and CV-SBP. In multivariable logistic regression analysis, higher quartiles of both SD-SBP and CV-SBP were independently associated with ALP positivity (e.g. SD-4; P  = 0.014; CV-4; P  = 0.009).</p><p><strong>Conclusion: </strong>Elevated VVV-SBP, assessed by SD and CV, is associated with impaired atrial conduction, highlighting its potential role as a predictor of atrial conduction abnormalities and a tool for AF risk stratification.</p>","PeriodicalId":8950,"journal":{"name":"Blood Pressure Monitoring","volume":" ","pages":"197-205"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}