ISRN urology最新文献_第3页

Should Finasteride Be Routinely Given Preoperatively for TURP? 非那雄胺应该作为TURP术前常规用药吗?

ISRN urology Pub Date : 2013-07-29 eCollection Date: 2013-01-01 DOI: 10.1155/2013/458353

O M Aboumarzouk, M Z Aslam, A Wedderburn, K Turner, O Hughes, H G Kynaston

{"title":"Should Finasteride Be Routinely Given Preoperatively for TURP?","authors":"O M Aboumarzouk, M Z Aslam, A Wedderburn, K Turner, O Hughes, H G Kynaston","doi":"10.1155/2013/458353","DOIUrl":"https://doi.org/10.1155/2013/458353","url":null,"abstract":"Objective. The aim of the review was to compare the use of finasteride to placebo in patients undergoing TURP procedures. Material & Methods. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (1966-November 2011), EMBASE (1980-November 2011), CINAHL, Clinicaltrials.gov, Google Scholar, reference lists of articles, and abstracts from conference proceedings without language restriction for studies comparing finasteride to placebo patients needing TURPs. Results. Four randomised controlled trials were included comparing finasteride to a placebo. A meta-analysis was not conducted due to the disparity present in the results between the studies. Three of the studies found that finasteride could reduce either intra- or postoperative bleeding after TURP. One study found finasteride to significantly lower the microvessel density (MVD) and vascular endothelial growth factor (VEGF). None of the studies reported any long-term complications related to either the medication or the procedure. Conclusion. finasteride reduces bleeding either during or after TURP. ","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"458353"},"PeriodicalIF":0.0,"publicationDate":"2013-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/458353","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31690582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Emergent intervention criterias for controlling sever bleeding after percutaneous nephrolithotomy. 经皮肾镜取石术后大出血控制的紧急干预标准。

ISRN urology Pub Date : 2013-07-28 eCollection Date: 2013-01-01 DOI: 10.1155/2013/760272

Ural Oguz, Berkan Resorlu, Mirze Bayindir, Tolga Sahin, Omer Faruk Bozkurt, Ali Unsal

{"title":"Emergent intervention criterias for controlling sever bleeding after percutaneous nephrolithotomy.","authors":"Ural Oguz, Berkan Resorlu, Mirze Bayindir, Tolga Sahin, Omer Faruk Bozkurt, Ali Unsal","doi":"10.1155/2013/760272","DOIUrl":"https://doi.org/10.1155/2013/760272","url":null,"abstract":"Objectives. To determine when emergent intervention for bleeding after percutaneous nephrolithotomy (PCNL) is required. Methods. We reviewed analysis data of 850 patients who had undergone PCNL in our center. Blood transfusion was needed for 60 (7%) patients during and/or after surgery. We routinely performed followup of the urine output per hour, blood pressure, and hemoglobin levels after PCNL. Five (0.6%) of them had severe bleeding that emergent intervention was needed. Results. The mean age of the 5 patients who had emergent surgery due to severe bleeding was 42.2 (19-56) years. Mean duration of surgery was 44.75 (25-65) minutes. Mean stone size was 27 (15-38) mm. Mean decrease of hemoglobin was 4.8 (3.4-5.8) ng/dL, and unit of transfused blood was 4.4 (3-6). Mean blood pH was 7.21. There were metabolic acidosis and anuria/oliguria in all these patients. One of 5 patients suffered from cardiopulmonary arrest because of massive bleeding four hours after the PCNL, and despite cardiac resuscitation, he died. Hemorrhaging was controlled by open surgery in the other 4 patients. Two patients experienced cardiac arrest during the open surgery but they responded to cardiac resuscitation. There were no metabolic asidosis and anuria/oliguria, and bleeding was managed only with blood transfusion for the other 55 patients. Conclusion. Severe bleeding after PCNL is rare and can be mortal. If metabolic asidosis and anuria/oliguria accompanied the drop of hemoglobin, emergent surgical intervention should be performed because vascular collapse may follow, and it may be too difficult to stabilise the patient. ","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"760272"},"PeriodicalIF":0.0,"publicationDate":"2013-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/760272","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31690583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Adverse effects of androgen deprivation therapy for prostate cancer: prevention and management. 雄激素剥夺治疗前列腺癌的不良反应:预防和处理。

ISRN urology Pub Date : 2013-07-25 eCollection Date: 2013-01-01 DOI: 10.1155/2013/240108

Petros Sountoulides, Thomas Rountos

{"title":"Adverse effects of androgen deprivation therapy for prostate cancer: prevention and management.","authors":"Petros Sountoulides, Thomas Rountos","doi":"10.1155/2013/240108","DOIUrl":"https://doi.org/10.1155/2013/240108","url":null,"abstract":"The prostate is an androgen-dependent organ. The increase, growth, homeostasis, and function of the prostate largely depend upon the intraprostatic and serum concentrations of androgens. Therefore, androgens are essential for the physiologic growth of prostatic epithelium. Prostate cancer, the second leading cause of death for men, is also androgen dependent, and androgen suppression is the mainstay of treatment for advanced and metastatic disease. In the state of metastatic disease, androgen suppression is a palliative treatment leading to a median progression-free survival of 18-20 months and an overall survival of 24-36 months. Theoretically, the majority of patients will develop hormone-refractory disease provided that they will not die from other causes. Although androgen suppression therapy may be associated with significant and sometimes durable responses, it is not considered a cure, and its potential efficacy is further limited by an array of significant and bothersome adverse effects caused by the suppression of androgens. These effects have potentially significant consequences on a variety of parameters of everyday living and may further decrease health-related quality of life. This review focuses on the aetiology of these adverse effects and provides information on their prevention and management. ","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"240108"},"PeriodicalIF":0.0,"publicationDate":"2013-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/240108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31690581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 49

Radical Cystectomy after BCG Immunotherapy for High-Risk Nonmuscle-Invasive Bladder Cancer in Patients with Previous Prostate Radiotherapy. 既往前列腺放疗的高危非肌浸润性膀胱癌患者行卡介苗免疫治疗后根治性膀胱切除术。

ISRN urology Pub Date : 2013-07-17 eCollection Date: 2013-01-01 DOI: 10.1155/2013/405064

Manoj V Rao, Marcus L Quek, Gautam Jayram, Chandy Ellimoottil, Timothy Sondej, Cory M Hugen, Robert C Flanigan, Gary D Steinberg

{"title":"Radical Cystectomy after BCG Immunotherapy for High-Risk Nonmuscle-Invasive Bladder Cancer in Patients with Previous Prostate Radiotherapy.","authors":"Manoj V Rao, Marcus L Quek, Gautam Jayram, Chandy Ellimoottil, Timothy Sondej, Cory M Hugen, Robert C Flanigan, Gary D Steinberg","doi":"10.1155/2013/405064","DOIUrl":"https://doi.org/10.1155/2013/405064","url":null,"abstract":"Purpose. Intravesical Bacillus Calmette-Guerin (BCG) immunotherapy is indicated for high-grade nonmuscle-invasive bladder cancer (NMIBC). The efficacy of BCG in patients with a history of previous pelvic radiotherapy (RT) may be diminished. We evaluated the outcomes of radical cystectomy for BCG-treated recurrent bladder cancer in patients with a history of RT for prostate cancer (PC). Methods. A retrospective chart review was performed to identify patients with primary NMIBC. We compared the outcomes of three groups of patients who underwent radical cystectomy for BCG-refractory NMIBC: those with a history of RT for PC, those who previously underwent radical prostatectomy (RP), and a cohort without PC or RT exposure. Results. From 1996 to 2008, 53 patients underwent radical cystectomy for recurrent NMIBC despite BCG. Those with previous pelvic RT were more likely to have a higher pathologic stage and decreased recurrence-free survival compared to the groups without prior RT exposure. Conclusion. Response rates for intravesical BCG therapy may be impaired in those with prior prostate radiotherapy. Patients with a history of RT who undergo radical cystectomy after failed BCG are more likely to be pathologically upstaged and have decreased recurrence-free survival. Earlier consideration of radical cystectomy may be warranted for those with NMIBC who previously received RT for PC. ","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"405064"},"PeriodicalIF":0.0,"publicationDate":"2013-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/405064","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31667658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Transurethral resection of prostate abscess: is it different from conventional transurethral resection for benign prostatic hyperplasia? 经尿道前列腺脓肿切除术:与常规经尿道前列腺增生切除术有何不同?

ISRN urology Pub Date : 2013-06-11 Print Date: 2013-01-01 DOI: 10.1155/2013/109505

Neeraj Kumar Goyal, Apul Goel, Satyanarayan Sankhwar, Divakar Dalela

{"title":"Transurethral resection of prostate abscess: is it different from conventional transurethral resection for benign prostatic hyperplasia?","authors":"Neeraj Kumar Goyal, Apul Goel, Satyanarayan Sankhwar, Divakar Dalela","doi":"10.1155/2013/109505","DOIUrl":"https://doi.org/10.1155/2013/109505","url":null,"abstract":"Purpose. To present our experience of prostate abscess management by modified transurethral resection (TUR) technique. Methods. Seventeen men with prostate abscess undergoing TUR between 2003 and 2011 were retrospectively analyzed. Details of demography, surgical procedures, complications, and followup were noted. Results. With a mean age of 61.53 ± 8.58 years, all patients had multifocal abscess cavities. Initially, 6 men underwent classical TUR similar to the technique used for benign prostatic enlargement (group 1). Next, 11 men underwent modified TUR (group 2) in which bladder neck and anterior zone were not resected. The abscess cavities resolved completely, and no patient required a second intervention. One patient in group 1 and three in group 2 had postoperative fever requiring parenteral antibiotics (P = 0.916). Three patients in group 1 had transient urinary incontinence, whereas none of the patients in group 2 had this complication (P = 0.055). Four and five men in group 1 and 2 reported retrograde ejaculation, respectively (P = 0.740). Conclusion. The modified technique of prostate resection edges over conventional TURP in the form of reduced morbidity but maintains its high success rate for complete abscess drainage. It alleviates the need for secondary procedures, having an apparent advantage over limited drainage techniques. Use of this technique is emphasized in cases associated with BPH and lack of proper preoperative imaging. ","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"109505"},"PeriodicalIF":0.0,"publicationDate":"2013-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/109505","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31569397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Efficacy and Safety of Enoxaparin for Preventing Venous Thromboembolic Events following Urologic Laparoscopic Surgery. 依诺肝素预防泌尿外科腹腔镜手术后静脉血栓栓塞事件的有效性和安全性。

ISRN urology Pub Date : 2013-06-02 Print Date: 2013-01-01 DOI: 10.1155/2013/415918

Takeo Nomura, Mika Takahashi, Kazunori Iwasaki, Tomoya Oribe, Mayuka Shinohara, Yuko Fukuda, Shinsuke Mizoguchi, Fuminori Sato, Hiromitsu Mimata

{"title":"Efficacy and Safety of Enoxaparin for Preventing Venous Thromboembolic Events following Urologic Laparoscopic Surgery.","authors":"Takeo Nomura, Mika Takahashi, Kazunori Iwasaki, Tomoya Oribe, Mayuka Shinohara, Yuko Fukuda, Shinsuke Mizoguchi, Fuminori Sato, Hiromitsu Mimata","doi":"10.1155/2013/415918","DOIUrl":"https://doi.org/10.1155/2013/415918","url":null,"abstract":"There is a paucity of definitive evidence that supports the use of enoxaparin to prevent venous thromboembolism (VTE) after urologic laparoscopic surgery. The purpose of this study was to evaluate the efficacy and safety of postoperative subcutaneous enoxaparin injection in patients who underwent urologic laparoscopic surgery. A total of 63 patients were evaluated from June 2010 to December 2012. All patients received postoperative prophylaxis with enoxaparin (2000 IU twice daily for 5 days). None of the patients treated with enoxaparin developed symptomatic VTE, but two cases (3.2%) of pulmonary embolism were noted before initial enoxaparin administration. Statistically significant differences were observed between the prothrombin time (PT) and activated partial thromboplastin time (APTT) values and D-dimer levels obtained at baseline and on day 7 after surgery; however, the PT and APTT values did not exceed the normal range. In addition, signs of any adverse events were not encountered in any of the patients treated with enoxaparin. The use of enoxaparin immediately after a surgery may confer valuable thromboprophylaxis benefits for urologic laparoscopic surgery. ","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"415918"},"PeriodicalIF":0.0,"publicationDate":"2013-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/415918","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31549205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The effect of in vitro oxidative stress on the female rabbit bladder contractile response and antioxidant levels. 体外氧化应激对母兔膀胱收缩反应及抗氧化水平的影响。

ISRN urology Pub Date : 2013-05-30 Print Date: 2013-01-01 DOI: 10.1155/2013/639685

Lisa Malone, Catherine Schuler, Robert E Leggett, Robert M Levin

{"title":"The effect of in vitro oxidative stress on the female rabbit bladder contractile response and antioxidant levels.","authors":"Lisa Malone, Catherine Schuler, Robert E Leggett, Robert M Levin","doi":"10.1155/2013/639685","DOIUrl":"https://doi.org/10.1155/2013/639685","url":null,"abstract":"Introduction. There are several bladder dysfunctions that are associated with oxidative stress to the urinary bladder. Two experimental models are known to cause this type of bladder damage. The first is direct oxidative damage caused by hydrogen peroxide (H2O2). The second is oxidative damage caused by ischemia followed by reperfusion (I/R). The specific aim of this study is to directly compare these two models of oxidative stress. Methods. Six adult female NZW rabbits were divided into two groups of three rabbits each. Eight full thickness strips from three rabbit bladders were taken for in vitro ischemia/reperfusion physiological analysis, while eight strips from three rabbit bladders were taken for in vitro H2O2 physiological analysis. All tissue was analyzed for total antioxidant activity (AA) and malondialdehyde (MDA) levels. In addition, samples of the water baths were also analyzed for AA. Results. In vitro I/R reduced the response to field stimulation (FS) to a significantly greater extent than the inhibition of the response to carbachol. In vitro H2O2 decreased all responses to approximately the same degree. Total AA levels at higher concentrations of H2O2 for all bath fluids were significantly higher than controls. MDA levels were significantly elevated in both models of oxidative stress. ","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"639685"},"PeriodicalIF":0.0,"publicationDate":"2013-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/639685","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31549206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Dipping technique for ureteroileal anastomosis in orthotopic ileal neobladder: 20-year experience in 670 patients-no stenosis with preservation of the upper tract. 原位回肠新膀胱输尿管油吻合术:20年670例经验-保留上尿路无狭窄。

ISRN urology Pub Date : 2013-05-26 Print Date: 2013-01-01 DOI: 10.1155/2013/725286

Mohamed M Wishahi, Hosam Elganzoury, Amr Elkhouly, Ahmed Mehena

{"title":"Dipping technique for ureteroileal anastomosis in orthotopic ileal neobladder: 20-year experience in 670 patients-no stenosis with preservation of the upper tract.","authors":"Mohamed M Wishahi, Hosam Elganzoury, Amr Elkhouly, Ahmed Mehena","doi":"10.1155/2013/725286","DOIUrl":"https://doi.org/10.1155/2013/725286","url":null,"abstract":"Objectives. Many techniques were described for ureteroileal anastomosis in orthotopic bladder substitution, ranging from nonrefluxing to refluxing techniques, all aiming at preservation of the upper tract. We describe our technique of dipping the ureter into the ileal pouch, which is simple and had no complications. Patients and Methods. Our technique implies dipping the ureter in the lateral side of the pouch, in right and left corners, with two rows of four sutures fixing the seromuscular layer of the ureter to the seromuscular layer of the ileal pouch. The procedure was applied in both normal ureteric calibre and dilated ureter. Total number of procedures done was 1,340 ureters in 670 patients after radical cystectomy for invasive carcinoma of the bladder of urothelial and nonurothelial cancer. Results. Followup of patients every six months and onward did not show stenosis in the ureteroileal anastomotic site. Filling of the ureter with contrast dye on ascending pouchogram was observed in patients who had considerably dilated ureters at the time of cystectomy. Normal ureter did not show clinical reflux but radiological filling of the ureter when the intravesical pressure exceeded the leak point pressure. Time to perform the dipping technique was 5-7 minutes for each site. Conclusion. Dipping technique for ureteroileal anastomosis in orthotopic ileal neobladder avoids the incidence of stenosis, preserves the upper tract, is a fast procedure, stands the evaluation in long-term followup, and was practiced successfully for twenty years.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"725286"},"PeriodicalIF":0.0,"publicationDate":"2013-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/725286","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31502962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Evaluating PSA Density as a Predictor of Biochemical Failure after Radical Prostatectomy: Results of a Prospective Study after a Median Follow-Up of 36 Months. 评估PSA密度作为根治性前列腺切除术后生化失败的预测因子:中位随访36个月后的前瞻性研究结果。

ISRN urology Pub Date : 2013-05-16 Print Date: 2013-01-01 DOI: 10.1155/2013/984951

Stavros Sfoungaristos, Petros Perimenis

{"title":"Evaluating PSA Density as a Predictor of Biochemical Failure after Radical Prostatectomy: Results of a Prospective Study after a Median Follow-Up of 36 Months.","authors":"Stavros Sfoungaristos, Petros Perimenis","doi":"10.1155/2013/984951","DOIUrl":"https://doi.org/10.1155/2013/984951","url":null,"abstract":"Purpose. To evaluate the predictive ability of PSA density for biochemical relapse after radical prostatectomy in patients operated for clinically localized disease and to compare its predictive strength with preoperative PSA and Gleason score. Patients and Methods. The study evaluated 244 patients with localized disease who underwent an open retropubic radical prostatectomy between February 2007 and April 2011. PSA was measured every 3 months after surgery with a mean follow-up period of 36 months. Two consecutive rises >0.2 ng/mL were considered as biochemical relapse. Results. Biochemical recurrence was observed in 71 (29.1%). A great correlation was found between relapse and PSA (P = 0.005), PSA density (P = 0.002), Gleason score (P = 0.015), pathological stage (P = 0.001), positive surgical margins (P = 0.021), and invasion of seminal vesicles (P < 0.001) and lymph nodes (P < 0.001). We also found that PSA density was associated with adverse pathological findings. In univariate and multivariate analysis both PSA (P = 0.006) and PSA density (P = 0.009) were found to be significant predictors for relapse in contrast to tumor grade. Conclusion. PSA density is a valuable parameter in estimating the danger of biochemical failure and it may increase predictive potential through the incorporation in preoperative nomograms.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"984951"},"PeriodicalIF":0.0,"publicationDate":"2013-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/984951","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31503902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Assessment of the effects of access count in percutaneous nephrolithotomy on renal functions by technetium-99m-dimercaptosuccinic Acid scintigraphy. 应用锝-99m-二巯基琥珀酸显像评价经皮肾镜取石术中通路计数对肾功能的影响。

ISRN urology Pub Date : 2013-05-08 Print Date: 2013-01-01 DOI: 10.1155/2013/827121

Abdullah Demirtaş, Mehmet Caniklioğlu, Mustafa Kula, Mustafa Sofikerim, Emre Can Akınsal, Mehmet Ali Ergül, Numan Baydilli, Oğuz Ekemekçioğlu

{"title":"Assessment of the effects of access count in percutaneous nephrolithotomy on renal functions by technetium-99m-dimercaptosuccinic Acid scintigraphy.","authors":"Abdullah Demirtaş, Mehmet Caniklioğlu, Mustafa Kula, Mustafa Sofikerim, Emre Can Akınsal, Mehmet Ali Ergül, Numan Baydilli, Oğuz Ekemekçioğlu","doi":"10.1155/2013/827121","DOIUrl":"https://doi.org/10.1155/2013/827121","url":null,"abstract":"Objective. To determine the effects of percutaneous nephrolithotomy on renal functions by using DMSA scintigraphy while considering access counts. Material and Methods. A total of 37 patients who had undergone percutaneous nephrolithotomy were included. Preoperative DMSA scans were performed a day before the surgery, whereas postoperative scans were randomized by evaluating them before (n = 25) and after (n = 12) the 6th postoperative month. Twenty-six of 37 cases underwent percutaneous nephrolithotomy with a single access site and 11 with multiple access sites. Results. There were no significant changes of total renal functions in the whole study group (P = 0.054). In the single access group, total functions were significantly elevated (P = 0.03) In the multiple access group, while treated site functions were significantly decreased (P = 0.01), total functions did not change significantly (P = 0.42). There was an insignificant decrease in those evaluated before the 6th postoperative month (P = 0.27) and an insignificant increase in the others (P = 0.11). Conclusion. We could not find a superiority of single access over multiple accesses. There is a temporary functional loss in the treated site.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"827121"},"PeriodicalIF":0.0,"publicationDate":"2013-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/827121","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31574515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8