ISRN urology最新文献_第4页

Outcomes after Radical Prostatectomy in Ghanaians: A Surgeon's Early Experience. 加纳人根治性前列腺切除术后的结果:一位外科医生的早期经验。

ISRN urology Pub Date : 2013-04-24 Print Date: 2013-01-01 DOI: 10.1155/2013/832496

Mathew Yamoah Kyei, Edward James Mensah, Samuel Gepi-Attee, Devine Kwami, Kwabena Ampadu, Emmanuel Asante, George Oko Klufio, Edward Donkoh Yeboah

{"title":"Outcomes after Radical Prostatectomy in Ghanaians: A Surgeon's Early Experience.","authors":"Mathew Yamoah Kyei, Edward James Mensah, Samuel Gepi-Attee, Devine Kwami, Kwabena Ampadu, Emmanuel Asante, George Oko Klufio, Edward Donkoh Yeboah","doi":"10.1155/2013/832496","DOIUrl":"https://doi.org/10.1155/2013/832496","url":null,"abstract":"Background. There is a lack of expertise in the procedure of open radical retropubic prostatectomy in West Africa therefore necessitating the training of urologists in the subregion in this procedure. Aim. This report looks at the early outcomes of a single surgeon in this procedure after an SIU fellowship. Methodology. A prospective study of the initial twenty consecutive patients with clinically localized prostate cancer that underwent open radical retropubic prostatectomy at the Korle Bu Teaching hospital, Accra. Results. The mean followup was 19.5 months (range 7 months-36 months). The mean age was 62.7 yrs. For the clinical stage, 60% were T1c and 40% T2a with a mean Gleason score of 6.5. The mean estimated blood loss was 1140.0 mLs with a transfusion rate of 70%. For the pathologic stage, pT2 cancers formed 60%, pT3 25%, and pT4 5% with a mean Gleason score of 6.8. No lymph node involvement was noted. The perioperative complications rate was 15%, a postoperative potency recovery rate of 78.6% with all the patients being continent of urine. The tPSA of 95% of the patients had remained less than 0.4 ng/mL. Conclusion. The SIU scholarship offers an avenue for training in radical prostatectomy for sub-Saharan Africa.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"832496"},"PeriodicalIF":0.0,"publicationDate":"2013-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/832496","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31458976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Sexually transmitted infections and male circumcision: a systematic review and meta-analysis. 性传播感染与男性包皮环切:一项系统回顾和荟萃分析。

ISRN urology Pub Date : 2013-04-16 Print Date: 2013-01-01 DOI: 10.1155/2013/109846

Robert S Van Howe

{"title":"Sexually transmitted infections and male circumcision: a systematic review and meta-analysis.","authors":"Robert S Van Howe","doi":"10.1155/2013/109846","DOIUrl":"https://doi.org/10.1155/2013/109846","url":null,"abstract":"The claim that circumcision reduces the risk of sexually transmitted infections has been repeated so frequently that many believe it is true. A systematic review and meta-analyses were performed on studies of genital discharge syndrome versus genital ulcerative disease, genital discharge syndrome, nonspecific urethritis, gonorrhea, chlamydia, genital ulcerative disease, chancroid, syphilis, herpes simplex virus, human papillomavirus, and contracting a sexually transmitted infection of any type. Chlamydia, gonorrhea, genital herpes, and human papillomavirus are not significantly impacted by circumcision. Syphilis showed mixed results with studies of prevalence suggesting intact men were at great risk and studies of incidence suggesting the opposite. Intact men appear to be of greater risk for genital ulcerative disease while at lower risk for genital discharge syndrome, nonspecific urethritis, genital warts, and the overall risk of any sexually transmitted infection. In studies of general populations, there is no clear or consistent positive impact of circumcision on the risk of individual sexually transmitted infections. Consequently, the prevention of sexually transmitted infections cannot rationally be interpreted as a benefit of circumcision, and any policy of circumcision for the general population to prevent sexually transmitted infections is not supported by the evidence in the medical literature.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"109846"},"PeriodicalIF":0.0,"publicationDate":"2013-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/109846","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31458975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Impact of self-watching double j stent insertion on pain experience of male patients: a randomized control study using visual analog scale. 自我观察双j型支架置入对男性患者疼痛体验的影响:采用视觉模拟量表的随机对照研究。

ISRN urology Pub Date : 2013-04-15 Print Date: 2013-01-01 DOI: 10.1155/2013/523625

Naser S Hussein, M R Norazan

{"title":"Impact of self-watching double j stent insertion on pain experience of male patients: a randomized control study using visual analog scale.","authors":"Naser S Hussein, M R Norazan","doi":"10.1155/2013/523625","DOIUrl":"https://doi.org/10.1155/2013/523625","url":null,"abstract":"Objective. To confirm safety and feasibility of double J stent insertion under local anesthesia and to assess the effect of detailed explanation and observing double J stent insertion on pain experience of male patients. Material and Methods. Eighty consenting males, randomized and divided prospectively into group A, who were allowed to observe DJ stent insertion, and group B, were not observed. All DJ stent insertions were done by senior urologist in operating urology room with or without fluoroscopy guidance. At the end of the procedure the vital signs and duration of the procedure were documented and patients were asked to fill unmarked 100 mm visual analogue pain scale (VAS) as soon as the surgeon leaves operating room. Results. Mean age of entire study group was 38.8 years; the majority of the patients had DJ stent insertion for obstructed ureteric stone, with uneventful outcomes. Postprocedural systolic blood pressure and mean pain using VAS showed statistically significant difference between groups A and B. Conclusion. DJ stent insertion under local anesthesia is a safe and feasible procedure. We recommended self-watching and detailed explanation to patients who underwent DJ stent insertion to reduce the pain and anxiety associated with the procedure.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"523625"},"PeriodicalIF":0.0,"publicationDate":"2013-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/523625","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31444817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Nonscalpel vasectomy as family planning method: a battle yet to be conquered. 非手术刀输精管结扎作为计划生育方法:一场尚未征服的战斗。

ISRN urology Pub Date : 2013-04-11 Print Date: 2013-01-01 DOI: 10.1155/2013/752174

Pankaj Kumar Garg, Bhupendra Kumar Jain, Deepti Choudhary, Ashish Chaurasia, Satya Deo Pandey

{"title":"Nonscalpel vasectomy as family planning method: a battle yet to be conquered.","authors":"Pankaj Kumar Garg, Bhupendra Kumar Jain, Deepti Choudhary, Ashish Chaurasia, Satya Deo Pandey","doi":"10.1155/2013/752174","DOIUrl":"https://doi.org/10.1155/2013/752174","url":null,"abstract":"Though nonscalpel vasectomy (NSV) technique was introduced in India in 1992 to increase male participation in family planning, it has failed to get adequate momentum and to achieve its goal. We conducted a cross-sectional questionnaire-based survey to get insight into apathy of men towards NSV. The study included 428 respondents. Most of the respondents (97.4%) were aware of NSV as a method for permanent male sterilization. The majority of them (97.2%) knew that NSV is done without any charge and cash incentive is given to the NSV client after the procedure. Though 68.0% respondents agreed that permanent sterilization is a possible option for them, only 34.1% respondents were willing to adopt NSV as a method of family planning. Fear of surgical procedure (40.7%), permanent nature of procedure (22.2%), and religious belief (19.0%) were the common reasons for unwillingness to adopt NSV. We conclude that there is a need to design and develop need-based information, education and communication (IEC) strategy to bridge the existing information gap among the eligible couples regarding NSV to improve its adoption. Involvement of community leaders and satisfied clients and utilization of television and radio would enhance the effectiveness of such interventions.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"752174"},"PeriodicalIF":0.0,"publicationDate":"2013-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/752174","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31444818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Robotic-assisted radical prostatectomy after the first decade: surgical evolution or new paradigm. 第一个十年后的机器人辅助根治性前列腺切除术:手术发展或新范式。

ISRN urology Pub Date : 2013-04-03 Print Date: 2013-01-01 DOI: 10.1155/2013/157379

Douglas W Skarecky

引用次数: 39

The effect of erythropoietin on ischemia/reperfusion injury after testicular torsion/detorsion: a randomized experimental study. 促红细胞生成素对睾丸扭转/扭转后缺血/再灌注损伤影响的随机实验研究。

ISRN urology Pub Date : 2013-03-31 Print Date: 2013-01-01 DOI: 10.1155/2013/351309

Fahimeh Kazemi Rashed, Babollah Ghasemi, Hamid Deldade Mogaddam, Mehran Mesgari

{"title":"The effect of erythropoietin on ischemia/reperfusion injury after testicular torsion/detorsion: a randomized experimental study.","authors":"Fahimeh Kazemi Rashed, Babollah Ghasemi, Hamid Deldade Mogaddam, Mehran Mesgari","doi":"10.1155/2013/351309","DOIUrl":"https://doi.org/10.1155/2013/351309","url":null,"abstract":"This study was conducted to investigate the protective effect of erythropoietin (EPO) on ischemia/reperfusion related changes after testicular torsion/detorsion. In a randomized experimental trial 30 male rats were randomly allocated into six equal groups of five rats each. Group I (orchiectomy for histopathologic examination), group II (sham operation), group III (torsion for 2 hours, and ischemia/detorsion for 24 hours, and orchiectomy); group IV (torsion for 2 hours, ischemia/detorsion for 24 hours with erythropoietin injection then orchiectomy), group V (torsion for 2 hours and detorsion and EPO injection and orchiectomy 1 week later, group VI (torsion for 2 hours/detorsion and orchiectomy 1 week later). Two groups (groups 4 and 5) received different protocols of erythropoietin administration after testicular torsion/distortion. other groups were not receiving erythropoietin. Johnsen's spermatogenesis scoring method and Cosentino's histologic staging method were used to assess main outcome measures of the study. After the experimentation, Johnsen's score in EPO Groups was statistically different from the score in some groups not receiving erythropoietin. Cosentino's score in EPO groups was statistically different from the score in all groups not receiving erythropoietin. Neovascularization, vascular necrosis, vascular congestion, edema, hemorrhage, and acute inflammation were observed in some groups. This study shows short-term protective efficacy of erythropoietin on rat testicular injury after ischemia/reperfusion.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"351309"},"PeriodicalIF":0.0,"publicationDate":"2013-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/351309","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31458974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Does combination therapy with desmopressin and tolterodine improve the treatment outcomes of patients with monosymptomatic nocturnal enuresis? A randomized clinical controlled trial. 去氨加压素和托特罗定联合治疗能改善单症状性夜间遗尿症患者的治疗效果吗?一项随机临床对照试验。

ISRN urology Pub Date : 2013-03-25 Print Date: 2013-01-01 DOI: 10.1155/2013/413146

Fahimeh Kazemi Rashed, Davoud Nourizade, Sakineh Hajebrahimi, Kamaleddin Hasanzade, Abdolreza Otoofat

{"title":"Does combination therapy with desmopressin and tolterodine improve the treatment outcomes of patients with monosymptomatic nocturnal enuresis? A randomized clinical controlled trial.","authors":"Fahimeh Kazemi Rashed, Davoud Nourizade, Sakineh Hajebrahimi, Kamaleddin Hasanzade, Abdolreza Otoofat","doi":"10.1155/2013/413146","DOIUrl":"https://doi.org/10.1155/2013/413146","url":null,"abstract":"Several therapeutic options have been described for children with nocturnal enuresis, but still their efficacy and outcomes are controversial. This study compares the combined Desmopressin and Tolterodine efficacy versus Desmopressin alone efficacy in the treatment of nocturnal enuresis. One hundred children 5-16 years old with nocturnal enuresis were enrolled in a randomized trial study and were assigned to two equal groups. In a double-blind manner, we used 2 mg of Tolterodine tablet plus 20 μ g of nasal Desmopressin in group A and 20 μ g of nasal Desmopressin plus placebo in group B. The two groups were matched for age and sex (P = 0.547, P = 0.414). The mean number of the wet nights was reduced in both groups (P < 0.001, P < 0.001). Upon ICCS scoring in the Tolterodine + Desmopressin group, 27 (54%) had full response, 17 (34%) had partial response, and 5 (10%) had an unsuccessful outcome. In the Desmopressin + placebo group, 17 (34%) had full response, 23 (46%) had partial response, and 10 (20%) had an unsuccessful outcome. The response in the Tolterodine + Desmopressin group was significantly higher (P = 0.049). Regarding the results, combined Tolterodine plus Desmopressin is slightly more effective than monotherapy.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"413146"},"PeriodicalIF":0.0,"publicationDate":"2013-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/413146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31361427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Frequent DNA Hypermethylation at the RASSF1A and APC Gene Loci in Prostate Cancer Patients of Pakistani Origin. 巴基斯坦裔前列腺癌患者RASSF1A和APC基因位点频繁的DNA高甲基化

ISRN urology Pub Date : 2013-01-01 Epub Date: 2013-01-30 DOI: 10.1155/2013/627249

Ahmed Yaqinuddin, Sohail A Qureshi, Shahid Pervez, Mohammed Umair Bashir, Ressam Nazir, Farhat Abbas

{"title":"Frequent DNA Hypermethylation at the RASSF1A and APC Gene Loci in Prostate Cancer Patients of Pakistani Origin.","authors":"Ahmed Yaqinuddin, Sohail A Qureshi, Shahid Pervez, Mohammed Umair Bashir, Ressam Nazir, Farhat Abbas","doi":"10.1155/2013/627249","DOIUrl":"https://doi.org/10.1155/2013/627249","url":null,"abstract":"DNA methylation has emerged as a potentially robust biomarker for prostate cancer (PCa). Since DNA methylomes appear to be disease as well as population specific, we have assessed the DNA methylation status of RASSF1A, APC, and p16 (potential biomarkers of PCa) in Pakistani population. Primary prostate cancer tissues were obtained from 27 formalin-fixed paraffin-embedded blocks (FFPE) of cancer patients who underwent radical prostatectomy and transurethral resection of prostate (TURP) during 2003-2008. As controls, twenty-four benign prostatic FFPE tissues were obtained from patients who underwent TURP for benign prostatic hyperplasia during 2008. DNA was extracted, and methylation-specific PCR was used to assess the methylation status for RASSF1A, APC, and p16 gene promoters. Our results revealed that the RASSF1A promoter was hypermethylated in all the tested cancer samples but was also hypermethylated in 3 out of 24 control tissues. The APC promoter was hypermethylated in 15 out of 27 cancer samples and in none of the control samples. Strikingly, none of the samples showed methylation at the p16 promoter. Our findings suggest that RASSF1A and APC gene promoters are frequently hypermethylated in the Pakistani population and therefore have the potential to develop into universally dependable biomarkers for detecting PCa.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"627249"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/627249","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31257597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

A dual 5α-reductase inhibitor dutasteride caused reductions in vascular density and area in benign prostatic hyperplasia. 双5α-还原酶抑制剂杜他雄胺引起良性前列腺增生血管密度和面积的减少。

ISRN urology Pub Date : 2013-01-01 Epub Date: 2013-01-17 DOI: 10.1155/2013/863489

Masayoshi Zaitsu, Akiko Tonooka, Koji Mikami, Mami Hattori, Yuta Takeshima, Toshimasa Uekusa, Takumi Takeuchi

{"title":"A dual 5α-reductase inhibitor dutasteride caused reductions in vascular density and area in benign prostatic hyperplasia.","authors":"Masayoshi Zaitsu, Akiko Tonooka, Koji Mikami, Mami Hattori, Yuta Takeshima, Toshimasa Uekusa, Takumi Takeuchi","doi":"10.1155/2013/863489","DOIUrl":"https://doi.org/10.1155/2013/863489","url":null,"abstract":"Objectives. Dutasteride, a dual 5α-reductase inhibitor, is used to treat benign prostatic hyperplasia. Nevertheless, its histopathological effects on the morphometrics of blood vessels and glands are still controversial. The aim here was to assess the histopathological effects of dutasteride in cases of benign prostatic hyperplasia in a retrospective study. Methods. Patients with benign prostatic hyperplasia more than 40 cm(3) in prostatic volume were administered 0.5 mg of dutasteride daily or left untreated prior to receiving a transurethral resection of the prostate. Images of sections stained with hematoxylin/eosin and with anti-CD31 antibody were analyzed. Results. In the dutasteride-treated group, the duration of administration was 16.3 ± 8.1 weeks. Artery/arteriole density and vein/venule density in benign prostatic tissue were both lower in the dutasteride-treated group than in the control group. The vein/venule area as a percentage of the whole area was also lower in the dutasteride-treated group, while the artery/arteriole area did not show a significant difference. Glandular/CD31-expressing vessel densities as well as glandular/CD31-expressing vessel areas were comparable between the two groups. Conclusions. Dutasteride reduced the artery/arteriole and vein/venule densities and the proportion of vein/venule area in the tissue of patients with benign prostatic hyperplasia.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":"2013 ","pages":"863489"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/863489","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31231651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Comparison of distal hypospadias repair in circumcised patients and uncircumcised patients. 包皮环切术患者与未行包皮环切术患者尿道下裂远端修复术的比较。

ISRN urology Pub Date : 2013-01-01 Epub Date: 2013-02-26 DOI: 10.1155/2013/957581

Fahimeh Kazemi Rashed, Rasool Gholizade

{"title":"Comparison of distal hypospadias repair in circumcised patients and uncircumcised patients.","authors":"Fahimeh Kazemi Rashed, Rasool Gholizade","doi":"10.1155/2013/957581","DOIUrl":"10.1155/2013/957581","url":null,"abstract":"Hypospadias is the most common anomaly in the male genital tract with an incidence of 0.8-8.2 per 1000 live male births. Routinely, hypospadias cases are repaired after one year of age, and it is recommended that a child with hypospadias not to be circumcised until hypospadias repair is completed. This study was conducted to determine whether or not circumcision prior to hypospadias repair increases the risk of complications. 30 circumcised patients and 30 persons without a history of circumcision and hypospadias were enrolled in this study and underwent surgery for hypospadias repair. The results of surgery compared between two groups. In the uncircumcised group, the mean durations of surgery and hospitalization were 55.61 ± 58.11 min and 3.17 ± 1.79 days. In circumcised group, the mean duration of surgery and hospitalization were 66.17 ± 33.65 minutes and 3.7 ± 1.62 days. There was no significant difference between these criteria and other complications of the two groups. This study shows that postoperative complications in circumcised distal hypospadias patients do not increase. Cosmetic and functional results were excellent. If there are failures in therapy and in case of postoperative complications, it is better to notice other factors such as infection.","PeriodicalId":89401,"journal":{"name":"ISRN urology","volume":" ","pages":"957581"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40230014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0