Biochemistry and Molecular Biology Education最新文献_第4页

Enhancing complex bioprocess learning through simulation technology and hybrid teaching: A case study in university education 通过模拟技术和混合教学加强复杂生物工艺学习：大学教育案例研究。

IF 1.2 4区教育学

Biochemistry and Molecular Biology Education Pub Date : 2024-05-06 DOI: 10.1002/bmb.21838

Davor Cotoras

{"title":"Enhancing complex bioprocess learning through simulation technology and hybrid teaching: A case study in university education","authors":"Davor Cotoras","doi":"10.1002/bmb.21838","DOIUrl":"10.1002/bmb.21838","url":null,"abstract":"The utilization of computer simulators in university education is progressively being embraced to offer students a practical exposure to industrial bioprocesses. Bioreactor computer simulators hold various advantages over conventional laboratory experiments, such as cost-effectiveness and enhanced safety. The research objective is to assess the effectiveness of integrating bioreactor computer simulators into hybrid teaching to promote active and collaborative learning experiences and evaluate their impact on student participation and understanding. A hybrid strategy combining synchronous, face-to-face, and online teaching has been implemented to enhance the teaching-learning processes in the Industrial Bioprocesses course for Biochemistry students. The simulation software BIOSTAT®T Yeast was used. This software models the production of ethanol with Saccharomyces cerevisiae through batch cultivation and the determination of the kLa value of a bioreactor. In the first simulation activity, students analyzed the software response based on parameter values input by the instructor, while in the second simulation activity, students autonomously used the computer simulator under the primary oversight of the instructor. The survey results indicate that the pedagogical innovation was positively received and significantly motivating for the students. Comparing student satisfaction surveys between the two simulation activities suggests that fostering student autonomy and engagement through simulation technology can improve satisfaction and learning outcomes in bioprocess education.","PeriodicalId":8830,"journal":{"name":"Biochemistry and Molecular Biology Education","volume":"52 5","pages":"519-526"},"PeriodicalIF":1.2,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140849657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and assessment of a virtual escape-room game for teaching industrial bioprocesses 开发和评估用于工业生物工艺教学的虚拟逃生游戏

IF 1.2 4区教育学

Biochemistry and Molecular Biology Education Pub Date : 2024-05-04 DOI: 10.1002/bmb.21837

Davor Cotoras, Felipe Valenzuela-Ibaceta, Diego Salas, Franco Cárdenas

{"title":"Development and assessment of a virtual escape-room game for teaching industrial bioprocesses","authors":"Davor Cotoras, Felipe Valenzuela-Ibaceta, Diego Salas, Franco Cárdenas","doi":"10.1002/bmb.21837","DOIUrl":"10.1002/bmb.21837","url":null,"abstract":"This article presents a study on the implementation of a virtual escape-room game as a novel teaching methodology in biochemistry education. The game aimed to engage students in producing monoclonal antibodies against SARS-CoV-2 while reinforcing theoretical concepts and fostering teamwork. Three versions of the game were tested, incorporating modifications to address student feedback on and improve the overall experience. The study employed a satisfaction survey to gather insights from students regarding their perception of the game. Results showed that the implementation of answer flexibility using RegEx had a significant positive impact on student satisfaction and motivation. The introduction of RegEx allowed for a more realistic and immersive gaming experience, as students could provide varied answers while still being evaluated correctly. Overall, the findings highlight the effectiveness of the game's design, the suitability of the Google Forms platform for distance learning, and the importance of incorporating answer flexibility through RegEx. These results provide valuable guidance for educators seeking to enhance student engagement and satisfaction through the use of escape-room games in biochemistry education.","PeriodicalId":8830,"journal":{"name":"Biochemistry and Molecular Biology Education","volume":"52 4","pages":"453-461"},"PeriodicalIF":1.2,"publicationDate":"2024-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140830480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing engagement and learning in advanced biochemistry through the application of flow theory 通过应用流动理论提高高级生物化学的参与度和学习效果

IF 1.2 4区教育学

Biochemistry and Molecular Biology Education Pub Date : 2024-04-30 DOI: 10.1002/bmb.21836

Jiafa Wu, Ying Wu, Shaobin Gu

{"title":"Enhancing engagement and learning in advanced biochemistry through the application of flow theory","authors":"Jiafa Wu, Ying Wu, Shaobin Gu","doi":"10.1002/bmb.21836","DOIUrl":"10.1002/bmb.21836","url":null,"abstract":"This study identified a lackluster classroom atmosphere in advanced biochemistry, characterized by low levels of active student participation in interactive communication and subpar quality of after-class learning tasks. The issues stemmed not only from students' learning attitudes, such as insufficient attention to the curriculum, but also from the course's inherent lack of challenge. Employing flow theory, we optimized teaching content, enhanced course difficulty, reformed assessment methods, and incorporated information-based teaching tools to redesign the instructional process. Through a questionnaire survey, students evaluated teaching effectiveness after implementation of the changes: a majority expressed satisfaction with the moderate difficulty of the course and enjoyment of the classroom instruction, and reported experiencing positive emotional flow. Peer experts commended the course, noting its lively atmosphere and the students' acquisition of both basic research methods and foundational knowledge. The findings will be used to continually enhance graduate students' innovation abilities and sense of achievement through ongoing reforms.","PeriodicalId":8830,"journal":{"name":"Biochemistry and Molecular Biology Education","volume":"52 5","pages":"512-518"},"PeriodicalIF":1.2,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140830578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Teaching effects of the online and offline flipped classroom model (FCM) in the post-epidemic era: Development and feasibility study 后流行病时代线上线下翻转课堂模式（FCM）的教学效果：开发与可行性研究

IF 1.2 4区教育学

Biochemistry and Molecular Biology Education Pub Date : 2024-04-22 DOI: 10.1002/bmb.21834

Shumin Wang, Yizhi Liu, Fengze Wang, Baochang Zhao, Lijun Gao, Miao Guo

{"title":"Teaching effects of the online and offline flipped classroom model (FCM) in the post-epidemic era: Development and feasibility study","authors":"Shumin Wang, Yizhi Liu, Fengze Wang, Baochang Zhao, Lijun Gao, Miao Guo","doi":"10.1002/bmb.21834","DOIUrl":"10.1002/bmb.21834","url":null,"abstract":"With the rapid development of multimedia technology, the student centered flipped classroom model (FCM) and massive open online courses (MOOCs) have been increasingly introduced and implemented in higher medical education. However, comparative analyses of the offline face-to-face FCM and completely online FCM have been rarely reported. In this study, we focused specifically on a set of flipped classrooms in which prerecorded videos were provided before class. Using the Zhihuishu platform as the major online course platform, our team built a MOOC and evaluated the teaching effectiveness of the FCM in both the offline face-to-face class and the online electronic live class for medical genetics education. Questionnaires, paper-based and oral exams were used to collect data on the teaching effects of the different teaching methods. We found that student satisfaction and overall student performance in the offline FCM group was significantly higher than that in the completely online teaching group. Although online FCM allowed students to play back and review anywhere and anytime after class, students taught in offline FCM had a significantly higher degree of knowledge mastery, had a deeper understanding of theoretical knowledge, and were better at knowledge comprehensive application. The effects of their training on genetic disease clinical diagnosis and treatment skills were significantly better, and their capacity for scientific research was also significantly improved. Our research discussed the advantages of the online courses and the problems brought about by using these technologies, and it provided insight into online teaching practices in the era of internet-based medical education.","PeriodicalId":8830,"journal":{"name":"Biochemistry and Molecular Biology Education","volume":"52 5","pages":"492-504"},"PeriodicalIF":1.2,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140803777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bridging the biochemistry lecture and laboratory courses: Construction and application of the “Innovative Experimental Design” module 衔接生物化学讲座和实验课程：创新实验设计 "模块的构建与应用

IF 1.2 4区教育学

Biochemistry and Molecular Biology Education Pub Date : 2024-04-15 DOI: 10.1002/bmb.21835

Pengfei Li, Boya Zhang, Shuaifei He, Yuqing Lu, Wenli Jiang, Qingsong Zhong, Shu Quan, Haizhen Wu, Mian Zhou

引用次数: 0

Comparative evaluation of open book and conventional assessment methods in medical undergraduate students 医学本科生开卷和传统评估方法的比较评估

IF 1.2 4区教育学

Biochemistry and Molecular Biology Education Pub Date : 2024-04-03 DOI: 10.1002/bmb.21831

Monica Irungbam, Shailata Prisi, Ritika Shrivastava, Binita Goswami

{"title":"Comparative evaluation of open book and conventional assessment methods in medical undergraduate students","authors":"Monica Irungbam, Shailata Prisi, Ritika Shrivastava, Binita Goswami","doi":"10.1002/bmb.21831","DOIUrl":"10.1002/bmb.21831","url":null,"abstract":"Medical science is a dynamic field of knowledge that is constantly broadening with upcoming clinical research and analysis. Traditional medical education has been focused on textbook-based recall assessments—closed book assessment (CBA). However, the availability of newer technologies has made the accessibility to encyclopedic knowledge expeditious, which demands for a new approach for medical education. As medical professionals, the purpose of learning should be higher cognitive skills such as interpretation and synthesis. So, analyzing students’ ability to comprehend the concepts and learning to apply it in a realistic context than merely recalling the facts has come into attention. In this study, we aimed to evaluate and compare the performance of 250 first-year MBBS students at Maulana Azad Medical College, New Delhi, India, between closed book and open book method for biochemistry. Students were divided into two groups, Group A and Group B, based on their average monthly internal assessment marks. CBA was followed by open book assessment (OBA) 1 week apart with similar questionnaire pattern and allotted time. A significant difference in average marks obtained by the two groups was observed in CBA. Group A scored better in CBA, but performance was comparable with Group B in OBA. OBA and CBA can contribute to an assessment program in part because of their complementary pros and cons, and OBA should not be thought of as an alternative to CBA, but their value may be in expanding beyond what is measured by CBA.","PeriodicalId":8830,"journal":{"name":"Biochemistry and Molecular Biology Education","volume":"52 4","pages":"436-441"},"PeriodicalIF":1.2,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140589807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-COVID-19 approach to teaching an undergraduate laboratory class focused on experimental design and data interpretation COVID-19 后以实验设计和数据解释为重点的本科实验课教学方法。

IF 1.2 4区教育学

Biochemistry and Molecular Biology Education Pub Date : 2024-03-28 DOI: 10.1002/bmb.21833

Jessie King, Barnaby Kelly, Nayla Rhein, Rhonda Rosengren

{"title":"Post-COVID-19 approach to teaching an undergraduate laboratory class focused on experimental design and data interpretation","authors":"Jessie King, Barnaby Kelly, Nayla Rhein, Rhonda Rosengren","doi":"10.1002/bmb.21833","DOIUrl":"10.1002/bmb.21833","url":null,"abstract":"To best prepare students for the real-world research environment, key skills, including experimental design, data analysis, communication of results, and critical thinking, should be key components of undergraduate science courses. Furthermore, the impact of the COVID-19 pandemic on in-person teaching has resulted in a need to develop courses that enable flexible learning. This paper details the laboratory component of a senior-level toxicology class that was developed to emphasize all these skills and allow for flexible learning. The aim of the laboratory class was for students to determine how curcumin protected against acetaminophen-induced hepatoxicity. To stimulate critical thinking, students were required to choose a maximum of four experiments from the six on offer. Before conducting an experiment, students stated a hypothesis and selected the appropriate treatment groups. Once an experiment was completed, students were given access to a complete dataset, on which they performed statistical analysis and drew conclusions. Students who were unable to attend the laboratory session in person were able to complete the required pre-lab work and access the dataset. Following each experiment, students could write a lab summary, and receive thorough feedback. The final assessment was a written manuscript of their findings as well as a chance to respond to reviewer comments. This teaching approach prioritized the critical thinking, analysis, and experimental design aspects of scientific research. Overall, this structure was well received by students and it could easily be adapted for use on other life science courses.","PeriodicalId":8830,"journal":{"name":"Biochemistry and Molecular Biology Education","volume":"52 4","pages":"442-452"},"PeriodicalIF":1.2,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bmb.21833","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140304631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of interactive mathematical simulations in Fundamentals of Biochemistry, a LibreText online educational resource, to promote understanding of dynamic reactions 在 LibreText 在线教育资源《生物化学基础》中使用交互式数学模拟，以促进对动态反应的理解。

IF 1.2 4区教育学

Biochemistry and Molecular Biology Education Pub Date : 2024-03-22 DOI: 10.1002/bmb.21830

Henry V. Jakubowski, Henry Agnew, Bartholomew Jardine, Herbert M. Sauro

{"title":"Use of interactive mathematical simulations in Fundamentals of Biochemistry, a LibreText online educational resource, to promote understanding of dynamic reactions","authors":"Henry V. Jakubowski, Henry Agnew, Bartholomew Jardine, Herbert M. Sauro","doi":"10.1002/bmb.21830","DOIUrl":"10.1002/bmb.21830","url":null,"abstract":"Biology is perhaps the most complex of the sciences, given the incredible variety of chemical species that are interconnected in spatial and temporal pathways that are daunting to understand. Their interconnections lead to emergent properties such as memory, consciousness, and recognition of self and non-self. To understand how these interconnected reactions lead to cellular life characterized by activation, inhibition, regulation, homeostasis, and adaptation, computational analyses and simulations are essential, a fact recognized by the biological communities. At the same time, students struggle to understand and apply binding and kinetic analyses for the simplest reactions such as the irreversible first-order conversion of a single reactant to a product. This likely results from cognitive difficulties in combining structural, chemical, mathematical, and textual descriptions of binding and catalytic reactions. To help students better understand dynamic reactions and their analyses, we have introduced two kinds of interactive graphs and simulations into the online educational resource, Fundamentals of Biochemistry, a LibreText biochemistry book. One is available for simple binding and kinetic reactions. The other displays progress curves (concentrations vs. time) for simple reactions and complex metabolic and signal transduction pathways. Users can move sliders to change dissociation and kinetic constants as well as initial concentrations and see instantaneous changes in the graphs. They can also export data into a spreadsheet for further processing, such as producing derivative Lineweaver-Burk and traditional Michaelis–Menten graphs of initial velocity (v0) versus substrate concentration.","PeriodicalId":8830,"journal":{"name":"Biochemistry and Molecular Biology Education","volume":"52 4","pages":"426-435"},"PeriodicalIF":1.2,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140183599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring in the classroom the relationship between alcohol intake and behavioral disorders through an animal model 在课堂上通过动物模型探索酒精摄入与行为障碍之间的关系。

IF 1.2 4区教育学

Biochemistry and Molecular Biology Education Pub Date : 2024-03-19 DOI: 10.1002/bmb.21829

Samanta Hernández-García, M. Alejandra Guerrero-Rubio, Paula Henarejos-Escudero, Pedro Martínez-Rodríguez, Fernando Gandía-Herrero

{"title":"Exploring in the classroom the relationship between alcohol intake and behavioral disorders through an animal model","authors":"Samanta Hernández-García, M. Alejandra Guerrero-Rubio, Paula Henarejos-Escudero, Pedro Martínez-Rodríguez, Fernando Gandía-Herrero","doi":"10.1002/bmb.21829","DOIUrl":"10.1002/bmb.21829","url":null,"abstract":"Alcohol consumption has profound effects on behavior, such as impaired judgment, addiction or even death. It is estimated that alcohol contributes to around three million deaths worldwide, 13.5% of them in young people with ages between 20 and 39 years. Consequently, it is necessary to raise awareness among college and high school students of the risk related to alcohol drinking. The small nematode Caenorhabditis elegans is an animal widely used as a model organism to study nearly all aspects of Biochemistry. It is a powerful tool to test the potential bioactivity and molecular mechanisms of natural compounds and drugs in vivo. Therefore, it is an interesting topic to include in an undergraduate course of Biotechnology, Biochemistry or Biology students among other scientific vocations. C. elegans is also used as a neurobiological model to evaluate substances' neurotoxicity and behavioral effects. The proposed experiment introduces students to the handling of this preclinical model and to the evaluation of behavioral alterations induced by chemicals in scientific research. The effects of different doses of ethanol on C. elegans behavior are studied using a versatile chemotaxis assay. This laboratory experiment is suitable for an undergraduate course. The practical session can be used in the global strategies of information and awareness of educational centres to mitigate the impact of alcohol abuse among students, both in formal courses or in Science fairs or exhibitions.","PeriodicalId":8830,"journal":{"name":"Biochemistry and Molecular Biology Education","volume":"52 4","pages":"474-479"},"PeriodicalIF":1.2,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bmb.21829","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140157538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The quantum mechanics of skincare: A context for the biochemistry curriculum 护肤品的量子力学：生物化学课程的背景。

IF 1.2 4区教育学

Biochemistry and Molecular Biology Education Pub Date : 2024-03-08 DOI: 10.1002/bmb.21827

Peter A. C. McPherson, Lynsey Alphonso, Ben M. Johnston

引用次数: 0