Biochemical Systematics and Ecology最新文献_第5页

Constituents from the leaves of Tricalysia oligoneura K. Schum (Rubiaceae) with antileishmanial and cytotoxic activities 具有抗利什曼原虫和细胞毒活性的少毛镰刀叶成分

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2026-04-01 Epub Date: 2025-12-08 DOI: 10.1016/j.bse.2025.105202

Gwladys Djikam Sime , Auguste Abouem A. Zintchem , Jeanne Louise Nkot , André Néhémie Bitombo , Mbabi Nyemeck Norbert II , Andrea Calcaterra , Khalid Mohammed Khan , Dominique Serge Ngono Bikobo , Muhammad Iqbal Choudhary , Dieudonné Emmanuel Pegnyemb

{"title":"Constituents from the leaves of Tricalysia oligoneura K. Schum (Rubiaceae) with antileishmanial and cytotoxic activities","authors":"Gwladys Djikam Sime , Auguste Abouem A. Zintchem , Jeanne Louise Nkot , André Néhémie Bitombo , Mbabi Nyemeck Norbert II , Andrea Calcaterra , Khalid Mohammed Khan , Dominique Serge Ngono Bikobo , Muhammad Iqbal Choudhary , Dieudonné Emmanuel Pegnyemb","doi":"10.1016/j.bse.2025.105202","DOIUrl":"10.1016/j.bse.2025.105202","url":null,"abstract":"<div><div>Phytochemical investigation of the leaves of Tricalysia oligoneura K. Schum led to the isolation and characterization of a novel oleanane type triterpen (1), a phytosphingosine type ceramide (2) along with one known steroid (3), three previously identified triterpenoids (4−6), one ent-kauran type diterpene (7), two known flavonoids (8−9), and one sugar derivative (10). Structure elucidation was accomplished through spectroscopic analyses and comparison with previously reported data. To the best of our knowledge, this is the first comprehensive report describing metabolites from Tricalysia oligoneura, thereby enriching the chemical profile of the species and providing valuable insights into the chemotaxonic relationships within the genus Tricalysia. In addition, all isolated compounds were evaluated for their antileishmanial and cytotoxic activities against Leishmania donovani 1S (MHOM/SD/62/1S) promastigotes and on RAW 264.7 macrophage cells respectively. Compounds 1 and 2 exhibited moderate leishmanicidal activities with IC50 values of 33.51 and 35 μM respectively in comparison with the positive control, Amphotericin B (IC50 = 0.0017 μM). The crude extract exhibited good activity (IC50 value 13.62 μg/mL) against the parasite but relatively low selectivity (SI = 5.05).</div><div>These findings suggest T. oligoneura may represent a promising source of new biologically active compounds further and support its chemotaxonomic placement within the Tricalysia genus.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"125 ","pages":"Article 105202"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145746950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic differentiation of Teucrium montanum L. (Lamiaceae) from serpentinite and calcareous habitats 蛇纹石和钙质生境中蒙古茶的代谢分化

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2026-04-01 Epub Date: 2025-11-27 DOI: 10.1016/j.bse.2025.105198

Nenad Zlatić , Danijela Mišić , Milica Milutinović , Uroš Gašić , Milan Stanković

{"title":"Metabolic differentiation of Teucrium montanum L. (Lamiaceae) from serpentinite and calcareous habitats","authors":"Nenad Zlatić , Danijela Mišić , Milica Milutinović , Uroš Gašić , Milan Stanković","doi":"10.1016/j.bse.2025.105198","DOIUrl":"10.1016/j.bse.2025.105198","url":null,"abstract":"<div><div>Plant secondary metabolites are ubiquitous in plants and play many physiological and ecological roles. Their species-specific qualitative and quantitative composition can vary within and among populations, and as influenced by environmental and genetic factors. Teucrium montanum L. is defined as a facultative serpentinophyte because, besides serpentinite (SER), it inhabits calcareous (CAL) habitats, where it experiences different physical-chemical soil characteristics (e.g. amount of trace elements, water, thermal regime). This research is conducted towards understanding the influence of the edaphic characteristics of SER and CAL habitats on the variability of methanol-soluble metabolites in T. montanum, aiming to identify high-resolution chemical markers to discriminate between ecotypes. Non-targeted metabolomics resulted in the identification of 95 compounds, mainly organic acids, phenolics, and terpenoids. Qualitative phytochemical composition is clearly differentiated in samples from CAL and SER habitats. The inter-population variability of twenty native populations from CAL and SER soils was investigated by metabolic profiling of aboveground parts targeting seventeen phenolic compounds. The quantitative composition of targeted metabolites varies among populations and is significantly influenced by edaphic factors. However, differences between SER and CAL habitats were statistically significant only for a few metabolites. CAL populations are characterized by higher chlorogenic and syringic acids content, while SER populations contain higher catechin, quercetin and isoquercitrin amounts. These compounds can be used as a fingerprint for a serpentinite/calcareous type of habitat and indicators of corresponding ecotypes of T. montanum.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"125 ","pages":"Article 105198"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145622529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Comparative phytochemical evaluation, antioxidant, antimicrobial and enzyme inhibitory properties of crude extracts of Ficus spp. 榕树粗提物的植物化学评价、抗氧化、抑菌及酶抑制性能比较。

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2026-04-01 Epub Date: 2025-11-21 DOI: 10.1016/j.bse.2025.105192

Shikha Dhiman, Dimple Guleria, Priyanka Sharma, Amit Kumar Sehgal

{"title":"Comparative phytochemical evaluation, antioxidant, antimicrobial and enzyme inhibitory properties of crude extracts of Ficus spp.","authors":"Shikha Dhiman, Dimple Guleria, Priyanka Sharma, Amit Kumar Sehgal","doi":"10.1016/j.bse.2025.105192","DOIUrl":"10.1016/j.bse.2025.105192","url":null,"abstract":"<div><div>Plants and plant-derived chemicals are crucial to be discovered and produced to facilitate the cure of many different kinds of ailments. The genus ‘Ficus’ represents an influential group of trees with tremendous therapeutic properties. This research was conducted using in vitro techniques to ascertain the comparative antioxidant capacity, antibacterial impact, enzyme inhibitory activity and phytochemical constituents of the leaves of F. hispida, F. benghalensis and F. semicordata by in vitro methods. Antioxidant potential was assessed by DPPH (1,1-diphenyl-2-picryl-hydrazyl) and a reducing power test. To evaluate the antibacterial potential disk-diffusion and broth microdilution methods were used. The phytochemical investigations were performed using quantitative assays, preliminary methods and Gas Chromatography-Mass Spectrometry. The antidiabetic potential was assessed by alpha-amylase inhibition and anti-ulcer activity was checked using urease inhibition assay. According to the study's findings, the leaves of F. benghalensis and F. semicordata displayed superior antioxidant properties to those of F. hispida. The strongest antibacterial potential was shown in the acetone extract from the leaf of F. semicordata against Escherichia coli. Findings revealed antidiabetic potential and the most noteworthy activity was demonstrated in the F. semicordata acetone extract, whereas the F. benghalensis leaf methanol extract exhibited the highest urease inhibition.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"125 ","pages":"Article 105192"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145555132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytochemicals from the flowers of Anthoshorea roxburghii (G.Don) P.S.Ashton & J.Heck. and their chemotaxonomic significance 刺梨花的植物化学成分（g.p onshorea roxburghii） P.S.Ashton & j.c heck。以及它们的化学分类意义

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2026-04-01 Epub Date: 2025-11-21 DOI: 10.1016/j.bse.2025.105180

Siriporn Yaisaeng , Mongkol Nontakitticharoen , Jarupong Prasopsuk , Oue-artorn Limtragool , Kitisak Poopasit , Surapon Saensouk , Chantana Boonyarat , Siripit Pitchuanchom

{"title":"Phytochemicals from the flowers of Anthoshorea roxburghii (G.Don) P.S.Ashton & J.Heck. and their chemotaxonomic significance","authors":"Siriporn Yaisaeng , Mongkol Nontakitticharoen , Jarupong Prasopsuk , Oue-artorn Limtragool , Kitisak Poopasit , Surapon Saensouk , Chantana Boonyarat , Siripit Pitchuanchom","doi":"10.1016/j.bse.2025.105180","DOIUrl":"10.1016/j.bse.2025.105180","url":null,"abstract":"<div><div>The phytochemical ne resveratrol oligomer, pauciflorol B (1); two flavonols, kaempferol (2) and quercetin (3); three flavonol glycosides, kaempferol-3- O-glucoside (4), quercetin-3-O-glucoside (5), and quercetin-3-O-rhamnoside (6); one steroid glycoside, β-sitosterol-3-O-β-d-glucopyranoside (7) and one phenolic glycoside, arbutin (8). Their structures were elucidated by spectroscopic techniques (IR, 1H NMR, 13C NMR, and 2D NMR) and mass spectrometry. Compound 1 exhibited stronger α-glucosidase inhibitory activity (IC50 = 213.09 ± 6.67 μM) than the reference drug acarbose (IC50 = 341.14 ± 6.34 μM). Compounds 4 and 8 were isolated from the Dipterocarpaceae family for the first time. Additionally, compounds 1, 4, 6, and 8 have not been reported in plants of the genus Shorea and Anthoshorea. Furthermore, the significance of these isolates from a chemotaxonomic approach was also presented.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"125 ","pages":"Article 105180"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145555131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A new aromatic glucoside from the leaves of Prunus persica and its chemotaxonomic significance 桃李叶中一种新的芳香糖苷及其化学分类意义

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2026-04-01 Epub Date: 2025-12-08 DOI: 10.1016/j.bse.2025.105204

Yujie Xu , Qing Liu , Changpeng Lu , Yan Yuan , Kai Tian , Liqun Guo , Yanhong Li , Jingxian Sun , Xiangzhong Huang

{"title":"A new aromatic glucoside from the leaves of Prunus persica and its chemotaxonomic significance","authors":"Yujie Xu , Qing Liu , Changpeng Lu , Yan Yuan , Kai Tian , Liqun Guo , Yanhong Li , Jingxian Sun , Xiangzhong Huang","doi":"10.1016/j.bse.2025.105204","DOIUrl":"10.1016/j.bse.2025.105204","url":null,"abstract":"<div><div>A previously undescribed aromatic glucoside, named prunusica (1), together with four known aromatic glucosides (2–5), five C13-norisoprenoid megastigmane glucosides (6–10), and three flavonoid glycosides (11–13), were isolated from the leaves of Prunus persica. Their structures was determined by comprehensive analysis, including 1D and 2D NMR spectroscopy, HR-ESI-MS, ECD calculations, and acid hydrolysis coupled with GC analysis. With the exception of 3 and flavonoid glycosides, other compounds were obtained from the plant for the first time. From the present investigation, Compounds 5, 7, and 10 were reported for the first time within the genus Prunus. These works enrich the chemical diversity of secondary metabolites in P. persica and provide valuable chemical basis for further chemotaxonomic and phytochemical research on this species.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"125 ","pages":"Article 105204"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145746949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flavonoid O- and C-glycosides from the leaves of four Zingiber species in Myanmar 缅甸四种生姜叶中的类黄酮O-和c -糖苷

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2026-04-01 Epub Date: 2025-12-16 DOI: 10.1016/j.bse.2025.105206

Tsukasa Iwashina , Nobuyuki Tanaka , Takahisa Nakane , Mu Mu Aung , Masao Goto , Yuko Ishikawa-Takano , Takayuki Mizuno

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Floral scent differentiation among species of the root-holoparasitic family Lennoaceae and its implications for pollination ecology 根茎全寄生植物菊科植物的花香分化及其传粉生态学意义

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2026-04-01 Epub Date: 2025-11-24 DOI: 10.1016/j.bse.2025.105196

Nadia Castro-Cárdenas , Pactli F. Ortega-González , Francisco J. Espinosa-García , Daniel Sánchez , Yolanda M. García-Rodríguez , Sonia Vázquez-Santana

{"title":"Floral scent differentiation among species of the root-holoparasitic family Lennoaceae and its implications for pollination ecology","authors":"Nadia Castro-Cárdenas , Pactli F. Ortega-González , Francisco J. Espinosa-García , Daniel Sánchez , Yolanda M. García-Rodríguez , Sonia Vázquez-Santana","doi":"10.1016/j.bse.2025.105196","DOIUrl":"10.1016/j.bse.2025.105196","url":null,"abstract":"<div><div>Floral scents play a pivotal role in the pollination of various plant species by enhancing floral attractiveness and facilitating pollination. In holoparasitic plants, such as those belonging to the Lennoaceae family, floral scents can serve as an essential recognition signal between flowers and pollinators, since only inflorescences are observable. In this study, we identified the chemical compounds of floral scents emitted by the four species of Lennoaceae, Lennoa madreporoides, Pholisma arenarium, P. culiacana, and P. sonorae. We conducted an in-situ volatile capture using the dynamic headspace method and chemical analysis via gas chromatography coupled to mass spectrometry (GC-MS). Our research unveiled the chemical diversity of floral scents within the Lennoaceae family, where alkanes, alkenes, monoterpenes, and benzenoids predominated. Moreover, we observed notable differences in the concentration and chemical profiles of floral scents between genera and species. P. culiacana had distinctive, diverse aroma with 46 unique compounds. Its aroma was clearly different from those of the other two Pholisma species and L. madreporoides due to its high concentration of ketones and monoterpenoids. L. madreporoides's aroma was distinct due to its 25 unique volatile compounds and the predominance of alkanes. This study significantly increases the knowledge of floral scent composition within the Lennoaceae family, and the new insights obtained provide an important advance in our understanding of the attraction mechanisms of root-parasitic floral ecology.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"125 ","pages":"Article 105196"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145622530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hairy root establishment and diterpenoid production in Scutellaria barbata 半边黄芩毛状根的建立及二萜类化合物的产生

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2026-01-01 Epub Date: 2025-10-28 DOI: 10.1016/j.bse.2025.105162

Yingying Qiu , Hui Yang , Qingwen Wu, Mengjiao Wu, Lesha Hu, Lili Huang

{"title":"Hairy root establishment and diterpenoid production in Scutellaria barbata","authors":"Yingying Qiu , Hui Yang , Qingwen Wu, Mengjiao Wu, Lesha Hu, Lili Huang","doi":"10.1016/j.bse.2025.105162","DOIUrl":"10.1016/j.bse.2025.105162","url":null,"abstract":"<div><div>Scutellaria barbata D. Don is a traditional Chinese herb medicine widely used to treat carbuncles and swellings. In recent years, a series of clerodane diterpenoid alkaloids have been isolated from S. barbata and exhibited significant anti-tumor activities. However, their contents are extremely low and confined to the aerial parts. Here we investigated weather and to what extent the biosynthesis of clerodane diterpenoid alkaloid is retained in the hairy roots derived from S. barbata. Hairy roots were successfully induced using direct injection method with Rhizobium rhizogenes strain K599. The optimal injection site was leaf petiole with an induction rate between 36 and 44 %, and the optimal growth medium is 6,7-V medium. However, UPLC-QTOF analysis showed the representative clerodane diterpenoid alkaloids, scutebarbatine A-D, were not detected in the established hairy roots. In contrast, abietane-type diterpenoids, including miltiradiene, abietatriene and ferruginol, which typically localized in the roots of native plant, were successfully detected by GC-MS. qRT-PCR analysis revealed that the transcripts of clerodane-type diterpene synthases (diTPSs), SbarKPS1 and SbarKPS2, were extremely low in hairy roots, while abietane-type diTPSs, SbarCPS1-2 and SbarKSL2, were expressed at substantial levels, which is consistent with the distribution of diterpenoids in hairy roots. MeJA treatment moderately enhanced expression of SbarKPSs; however, scutebarbatine A-D were not induced within 1–7 days post-treatment. Taken together, this study established the hairy root system of S. barbata and implicate low expression of key diterpene biosynthetic enzymes as a major limiting factor in diterpenoid production in the established hairy root.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105162"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lignan contents of Schisandra chinensis from different cultivation sites and their relationship between fruit traits and soil properties 不同产地五味子木脂素含量及其与果实性状和土壤性状的关系

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2026-01-01 Epub Date: 2025-11-01 DOI: 10.1016/j.bse.2025.105170

Lin Liu, Bianbin Qi, Yue Liu, Jialin Liu, Hongmiao Li, Xiaotian Su, Liangying Zhang

{"title":"Lignan contents of Schisandra chinensis from different cultivation sites and their relationship between fruit traits and soil properties","authors":"Lin Liu, Bianbin Qi, Yue Liu, Jialin Liu, Hongmiao Li, Xiaotian Su, Liangying Zhang","doi":"10.1016/j.bse.2025.105170","DOIUrl":"10.1016/j.bse.2025.105170","url":null,"abstract":"<div><div>Schisandra chinensis, a traditional Chinese medicinal herb, is extensively cultivated in Liaoning Province. However, the quality of medicinal herbs varies due to the influence of the growth environment. This study investigated the differences in the six major lignans of S. chinensis from 25 cultivation sites. The results showed that schisandrol A was the predominant lignan, followed by schisandrin B and schisandrin A. Strong positive correlations were observed between schisandrol A, schisantherin A, and schisandrin A, as well as between schisandrin B, schisandrol B, and schisandrin C. The cultivation sites were categorized into four distinct clades, representing three types of lignan composition. OPLS-DA identified schisandrin B, schisandrin A, and schisandrol A as discriminant markers. Additionally, the main factors influencing lignan content were examined in relation to soil properties and fruit traits. Among the soil chemical properties across the cultivation sites, available Mn significantly influenced fruit traits. Fruit traits also exhibited considerable effect on lignan content, with most indicators negatively correlated with lignan content. The findings highlight the complexity of lignan accumulation and suggest that evaluating total lignan content solely based on schisandrol A is challenging. The study provides a scientific basis for quality evaluation and systematic cultivation of S. chinensis.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105170"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145424694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytochemical investigation of Commiphora stocksiana (Engl.) Engl. and its comparative metabolomic study with Commiphora wightii (Arn.) Bhandari. Using HPLC-MS-Qtof 黄花香薷植物化学研究（英文版）心血管病。及其与白粉虱的比较代谢组学研究班达里。使用HPLC-MS-Qtof

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2026-01-01 Epub Date: 2025-09-12 DOI: 10.1016/j.bse.2025.105122

Shivani Bhati, Aruna Joshi

{"title":"Phytochemical investigation of Commiphora stocksiana (Engl.) Engl. and its comparative metabolomic study with Commiphora wightii (Arn.) Bhandari. Using HPLC-MS-Qtof","authors":"Shivani Bhati, Aruna Joshi","doi":"10.1016/j.bse.2025.105122","DOIUrl":"10.1016/j.bse.2025.105122","url":null,"abstract":"<div><div>The oleo-gum resins and essential oils from genus Commiphora Jacq. have been widely used commercially for different medicinal purposes all over the world. This study presents a tentative phytochemical profile of one of its lesser-known endangered species Commiphora stocksiana (Engl.) Engl. and a comparative assessment with Commiphora wightii (Arn.) Bhandari stem fractions. The fractionation was performed across three different solvent polarities; analysis of the fractions were performed using HPLC-MS-QToF in both positive and negative electrospray ionization (ESI) modes. The statistical analysis performed for the comparative assessment of the two species revealed that methanolic fractions displayed the most pronounced species-level separation, followed by moderate differentiation in ethyl acetate fractions, while petroleum ether fractions exhibited considerable overlap, indicating compositional similarity. The spectral library-based comparison of the features observed in each fraction led to tentative identification of 61 metabolites of varying compound classes in C. stocksiana. Further MS/MS fragmentation analysis of some features observed in petroleum ether fraction of C. stocksiana revealed the presence of Guggulsterone E, confirmed by alignment with a positive control from C. wightii using exact ion chromatogram tool in MS-DIAL. These findings were verified using HPLC analysis by using reference standard mix of Guggulsterone E and Z isomer. Additional feature showed retro-Diels-Alder (RDA) type cleavage of precursor ions, suggesting the presence of ursane- and oleanane-type pentacyclic triterpenoids, highly similar to the boswellic acid derivatives.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105122"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145046805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0