Biochemical Systematics and Ecology最新文献_第5页

Inter and intraspecies variability of terpene profiles of four spruce species growing in the Czech Republic: a chemotaxonomic study 捷克共和国生长的四种云杉种间和种内萜烯谱的变异性：一项化学分类研究

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2025-07-29 DOI: 10.1016/j.bse.2025.105095

Alexandra Malhocká, Martina Švábová

{"title":"Inter and intraspecies variability of terpene profiles of four spruce species growing in the Czech Republic: a chemotaxonomic study","authors":"Alexandra Malhocká, Martina Švábová","doi":"10.1016/j.bse.2025.105095","DOIUrl":"10.1016/j.bse.2025.105095","url":null,"abstract":"<div><div>Inter and intraspecific variability in terpene abundance is a key marker in chemotaxonomic studies of conifers. Quantitative distribution as well as qualitative trends in terpene abundance in Norway spruce, Siberian spruce, blue spruce, and Sitka spruce were identified using cold solvent extraction combined with gas chromatography/mass spectrometry. The spruces species showed a high variability of terpene profiles within studied parts of the trees but always the same qualitative trend corresponding to the assignment to Picea and Casista sections. While in Norway spruce and Siberian spruce (section Picea) α-pinene, camphene, bornyl acetate dominated in the needles, α-pinene, β-pinene, and pimara-7,15-dien-3-one were the most abundant in the resins from tree trunks. In contrast, α-pinene, β-pinene, and methyl abietate dominated in the cones. While limonene, camphene and camphor dominated in the needles of section Casista, high amounts of α-pinene and thunbergol were reached in the resins from tree trunks. In contrast, α-pinene, β-pinene, and Labda-8(20),14-dien-13-ol dominated in the cones. Between P. abies and cultivars ‘Cupressina’ and 'Finedonensis' a significant homogeneity in the qualitative trends of terpene abundance was revealed. The distinguishing terpene was diterpene thunbergol. Significant seasonal variability in the abundance of the monoterpenes tricyclene, β-pinene, and bornyl acetate, and the sesquiterpene germacrene D-4-ol was found. In conclusion, the results confirmed high chemotype and genotype dependence of spruce species in terpene abundance, with the exception of β-phellandrene in the 'Finedonensis', whose abundance was highly unstable.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105095"},"PeriodicalIF":2.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemical constituents from the seeds of Khaya grandifoliola C.DC; their chemophenetic significance and antibacterial activities 大叶茶籽化学成分的研究它们的化学化学意义和抗菌活性

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2025-07-29 DOI: 10.1016/j.bse.2025.105104

Akafack Lyliane Sorelle , Appolinaire Kene Dongmo , Billy Toussie Tchegnitegni , Blandine Kampa-kuemkon Nkenfou , Jean Francois Zeutsop , Raymond Ngansop Nono , Pépin Nkeng-Efouet Alango , Bruno Ndjakou Lenta , Norbert Sewald , Jean Rodolphe Chouna

{"title":"Chemical constituents from the seeds of Khaya grandifoliola C.DC; their chemophenetic significance and antibacterial activities","authors":"Akafack Lyliane Sorelle , Appolinaire Kene Dongmo , Billy Toussie Tchegnitegni , Blandine Kampa-kuemkon Nkenfou , Jean Francois Zeutsop , Raymond Ngansop Nono , Pépin Nkeng-Efouet Alango , Bruno Ndjakou Lenta , Norbert Sewald , Jean Rodolphe Chouna","doi":"10.1016/j.bse.2025.105104","DOIUrl":"10.1016/j.bse.2025.105104","url":null,"abstract":"<div><div>Chemical exploration of the CH2Cl2/MeOH extract of the seeds of Khaya grandifoliola C.DC led to the isolation of one previously unreported limonoid (7), together with 19 known compounds. The structures of all the isolated compounds were established by interpretation of their spectroscopic and spectrometric data, including 1D and 2D NMR and HRESIMS analysis. The full NMR assignment of 2α,3β-dihydroxymexicanolide (2) and that of the new compound 7 were reported together with the chemophenetic significance of the isolated compounds. The crude extract, fractions, and some isolates were screened for their antibacterial properties against five pathogenic strains: three Gram negative, Escherichia coli ATCC25922, Klebsiella pneumoniae NR41BB, Salmonella typhimurium (clinical isolate), and two Gram positive, Staphylococcus aureus ATCC12600 and Enterococcus faecalis ATCC51299. Fraction D displayed a significant activity against Escherichia. coli ATCC25922 with an MIC value of 31.25 μg/mL. Among the pure compounds, the best MIC (31.25 μg/mL) was obtained with proceranolide (1) against E. coli ATCC25922. The isolates were also screened for their cytotoxic activity against the human cervix carcinoma KB-3-1 cell line, and no significant activity was observed.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105104"},"PeriodicalIF":2.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144723655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemical constituents from the branches of Broussonetia papyrifera and their chemotaxonomic significance 纸莎草分枝的化学成分及其化学分类意义

IF 2 4区生物学

Biochemical Systematics and Ecology Pub Date : 2025-07-28 DOI: 10.1016/j.bse.2025.105097

Cong-Xi Gao , Wen-Jie Ma , Wu-Yan Chen , Hong-Ji Shi , Ding Tian , Jian-Lin Hu , Kou Wang

{"title":"Chemical constituents from the branches of Broussonetia papyrifera and their chemotaxonomic significance","authors":"Cong-Xi Gao , Wen-Jie Ma , Wu-Yan Chen , Hong-Ji Shi , Ding Tian , Jian-Lin Hu , Kou Wang","doi":"10.1016/j.bse.2025.105097","DOIUrl":"10.1016/j.bse.2025.105097","url":null,"abstract":"<div><div>Phytochemical investigation of the branches of Broussonetia papyrifera (Moraceae) resulted in the isolation of thirty-one compounds, including: nine flavans (1–9), five diarylpropanoids (10–14), three steroids (15–17), two anthraquinones (18, 19), two hydroxybenzoic acids (20, 21), three terpenoids (22, 25, 27), six phenylpropanoids (23, 24, 26, 29–31), and one heterocyclic compound (28). Among them, seven compounds (1, 9, 10, 13, 14, 23, and 31) were isolated from the Moraceae family for the first time. Evaluation of the flavan and diarylpropanoid compounds (1–14) for anti-atopic dermatitis (AD) activity demonstrated that eight compounds inhibited IL-13 secretion in HaCaT cells. Notably, compounds 2, 10, and 12 displayed the most potent activity, reducing IL-13 secretion below levels achieved by the positive control dexamethasone. Furthermore, the chemotaxonomic significance of the isolated constituents is discussed in detail.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105097"},"PeriodicalIF":2.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lignans from the leaves of Pieris formosa and their chemotaxonomic significance 台湾梨叶木脂素及其化学分类意义

IF 1.4 4区生物学

Biochemical Systematics and Ecology Pub Date : 2025-07-26 DOI: 10.1016/j.bse.2025.105093

Changfeng Ye , Yuanyuan Feng , Yenan Sun , Jiaxing Yu , Yan Wu , Guijuan Zheng , Adila Abudurexiti , Guangmin Yao

引用次数: 0

Phytochemical study of the stem bark of Erismadelphus exsul Mildbr. (Vochysiaceae) and chemotaxonomic significance of the isolated secondary metabolites 黄樟茎皮的植物化学研究。（Vochysiaceae）及其分离次生代谢物的化学分类意义

IF 1.4 4区生物学

Biochemical Systematics and Ecology Pub Date : 2025-07-25 DOI: 10.1016/j.bse.2025.105094

Marc II Mabounda Moutsinga , Guy Raymond Feuya Tchouya , Paulin Nkolo , Hibrahim Foundikou , Rudy-Karelle Lemah-Yottoh , Ghismel Nzamba Moussavou , Berthier Edouard Nkizo'o Ella , Yugal Kishore Mohanta , Jacques Lebibi

{"title":"Phytochemical study of the stem bark of Erismadelphus exsul Mildbr. (Vochysiaceae) and chemotaxonomic significance of the isolated secondary metabolites","authors":"Marc II Mabounda Moutsinga , Guy Raymond Feuya Tchouya , Paulin Nkolo , Hibrahim Foundikou , Rudy-Karelle Lemah-Yottoh , Ghismel Nzamba Moussavou , Berthier Edouard Nkizo'o Ella , Yugal Kishore Mohanta , Jacques Lebibi","doi":"10.1016/j.bse.2025.105094","DOIUrl":"10.1016/j.bse.2025.105094","url":null,"abstract":"<div><div>Erismadelphus exsul Mildbr. belongs to family Vochysiaceae and is traditionally important to native communities of Gabon for its medicinal value and frequently use in rituals. It has been highly valued for centuries for its application in the treatment of various diseases and the preservation of spiritual health through traditional knowledge. Owing to a deep scientific investigation, eleven known compounds have been isolated from the CH2Cl2/MeOH (1:1) extract of the stem bark using liquid-liquid extraction and chromatographic separation methods, and identified through spectroscopic analysis and physical data in comparison with data from the existing literature. These compounds include β-sitosterol (1), stigmasterol (2), betulinic acid (3), oleanolic acid (4), ursolic acid (5), sitosterol 3-O-β-d-glucopyranoside (6), genistein 7-O-glucoside-6″-malonate (7), 3′-O-methyl-3,4-O,O-methylidene ellagic acid (8), 3-O-methylellagic acid-3′-O-α-rhamnopyranoside (9), bellericagenin A (10) and bellericaside A (11). Current work deals with the isolation and identification of the compounds, along with the discussion of their chemotaxonomic significance for future exploration in successful use in pharmaceutical product development.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105094"},"PeriodicalIF":1.4,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144702590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive UHPLC-Q-TOF-IMS based non-targeted metabolome analysis of Rhynchostylis retusa. L Blume revealed chemometric variations. A case study from Western Himalayas 基于UHPLC-Q-TOF-IMS的柳条草非靶向代谢组学综合分析L Blume揭示了化学计量学的变化。西喜马拉雅地区的案例研究

IF 1.4 4区生物学

Biochemical Systematics and Ecology Pub Date : 2025-07-23 DOI: 10.1016/j.bse.2025.105092

Anjna Kumari , Rishabh Kaundal , Pallavi Kumari , Dinesh Kumar

{"title":"Comprehensive UHPLC-Q-TOF-IMS based non-targeted metabolome analysis of Rhynchostylis retusa. L Blume revealed chemometric variations. A case study from Western Himalayas","authors":"Anjna Kumari , Rishabh Kaundal , Pallavi Kumari , Dinesh Kumar","doi":"10.1016/j.bse.2025.105092","DOIUrl":"10.1016/j.bse.2025.105092","url":null,"abstract":"<div><div>Rhynchostylis retusa (R. retusa) is an epiphytic medicinal orchid native to tropical and subtropical regions, including Western Himalayas. Pharmacological reports suggested its antimicrobial, anti-inflammatory, and antioxidant activities. Indian western Himalayas, especially Himachal Pradesh, provide a unique environment to grow R. retusa due to distinct ecological conditions, known to influence biosynthesis of metabolites. Thus, this study was focused to find out the chemometric variations using UHPLC-Q-TOF-IMS among differential geographical roots of R. retusa. Comprehensively, R. retusa roots of four distinct locations (Hamirpur, Mandi, Bilaspur and Kangra) revealed the identification of 43 compounds, belonging to polyphenols, flavonoids, stilbenes etc. Further, identified metabolites were found varied at different locations due to the ecological conditions. These variations were clearly observed with chemometric analysis of different samples. The principal component and hierarchical clustering analysis showed abundance of polyphenols, similarities and discrimination, including their metabolites among the locations. This is the first report on the comprehensive metabolite profiling of R. retusa and that will be helpful to differentiate or assess the quality of material based on chemical makeup. Moreover, chromatographic coupled with mass spectrometry identified chemical makeup of R. retusa, that could be the responsible key components of traditional health benefits and reported therapeutic activities.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105092"},"PeriodicalIF":1.4,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144686857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of habitat and herbivory stress on essential oil yield in Cinnamomum longipaniculatum 生境和草食胁迫对长尖香樟精油产量的影响

IF 1.4 4区生物学

Biochemical Systematics and Ecology Pub Date : 2025-07-21 DOI: 10.1016/j.bse.2025.105091

Xin-Min Liu , Ying-zhou Chen , Qin Liu , Qiong-zhi Hu , Ya Tang

{"title":"Effects of habitat and herbivory stress on essential oil yield in Cinnamomum longipaniculatum","authors":"Xin-Min Liu , Ying-zhou Chen , Qin Liu , Qiong-zhi Hu , Ya Tang","doi":"10.1016/j.bse.2025.105091","DOIUrl":"10.1016/j.bse.2025.105091","url":null,"abstract":"<div><div>Leaf of Cinnamomum longipaniculatum contains around 60 % essential oil (EO) being 1,8-cineole the main component. This is the biggest EO producing tree species in China and Sichuan of China has a plantation of 36 000 ha. Despite many studies, EO content of very young leaves and its variation of a full year is understudied and the effects of different habitats and insect herbivore on EO yield is poorly understood. A 12-month long, half-month interval monitoring of leaf EO content in an industrial farm revealed an EO content ranging from 2.06 % to 4.25 %. Half-monthly EO content varied from 1.76 % in early March to 2.75 % in early September in fresh leaves, and from 2.55 % in late October to 4.13 % in early April in dry leaves. Leaf EO content was significantly higher in dry than in fresh (3 % versus 2.03 %), two-year old than one-year old (3.06–4.25 % versus 2.06–3.22 %) leaves. EO content differed significantly on different slope aspects (3.87 % on southwest, 3.52 % on southeast, 3.26 % on east, and 2.85 % on northwest), and on different slope gradients (2.99 % on 0–10° slopes, 3.27 % on 10–20° slopes, 3.80 % on 20–30° slopes). Insect herbivore significantly increased EO content and it was 2.91–3.63 % in damaged versus 2.06–3.22 %) in undamaged leaves. Results indicate that plantations on marginal lands with thin, poor and dry soils on steep slopes not only produce higher EO yield but does not compete with cereal crops for croplands. Fertilizers, insecticides and irrigation are unnecessary. This study provides important information for design and management of C. longipaniculatum plantations.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105091"},"PeriodicalIF":1.4,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144680345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phenolics from Toxicodendron vernicifluum (Stokes) F. A. Barkley (Anacardiaceae) and their chemotaxonomic significance 刺心科刺心藤的酚类物质及其化学分类意义

IF 1.4 4区生物学

Biochemical Systematics and Ecology Pub Date : 2025-07-17 DOI: 10.1016/j.bse.2025.105090

Cai-Wen Meng , Wen-Jing Zu , Jie Liu , Xue Qiu , Hong-Yun Bai , Jian-Yu Liu , Yong-Nan Xu , Mei-Chen Li

{"title":"Phenolics from Toxicodendron vernicifluum (Stokes) F. A. Barkley (Anacardiaceae) and their chemotaxonomic significance","authors":"Cai-Wen Meng , Wen-Jing Zu , Jie Liu , Xue Qiu , Hong-Yun Bai , Jian-Yu Liu , Yong-Nan Xu , Mei-Chen Li","doi":"10.1016/j.bse.2025.105090","DOIUrl":"10.1016/j.bse.2025.105090","url":null,"abstract":"<div><div>Phytochemical investigations on the heartwood of Toxicodendron vernicifluum (Stokes) F.A. Barkley resulted in the isolation of twenty-three compounds, including four flavonols (1-4), two flavones (5–6), one flavanone (7), two dihydroflavonols (8–9), three chalcones (10–12), two flavan-3,4-diols (13–14), seven tannins (15–21), and two phenylpropanoids (22–23). Structural elucidation was achieved through spectroscopic analysis (including NMR, MS, and UV) combined with comparison to previously reported data. Except for compound 1, all other compounds (2–23) were isolated from the genus Toxicodendron for the first time, and especially seventeen of them (2, 4–13, 15–19 and 23) were also isolated from the family Anacardiaceae for the first time. The chemotaxonomic significance of these isolates was also discussed.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105090"},"PeriodicalIF":1.4,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of an endophytic Streptomyces sp. from the liverwort Bazzania trilobata: A new source for abyssomicins 三叶棘球藻内生链霉菌的研究：一种新的深海菌素来源

IF 1.4 4区生物学

Biochemical Systematics and Ecology Pub Date : 2025-07-09 DOI: 10.1016/j.bse.2025.105077

Preston K. Manwill , Zach Shank , Thomas Wieboldt , Leah C. Blasiak , Russell T. Hill , Harinantenaina L. Rakotondraibe

{"title":"Investigation of an endophytic Streptomyces sp. from the liverwort Bazzania trilobata: A new source for abyssomicins","authors":"Preston K. Manwill , Zach Shank , Thomas Wieboldt , Leah C. Blasiak , Russell T. Hill , Harinantenaina L. Rakotondraibe","doi":"10.1016/j.bse.2025.105077","DOIUrl":"10.1016/j.bse.2025.105077","url":null,"abstract":"<div><div>Liverworts are the most ancient group of land plants and share intimate symbioses with microorganisms, yet their endophytes have remained unexplored as a source of unique compounds. As part of an ongoing search for novel and bioactive compounds from microbial associates of liverworts, an endophytic Streptomyces sp. LH003 cultured from Bazzania trilobata was identified as a new source for abyssomicins. Three compounds, namely abyssomicin 2 (1), abyssomicin 4 (2), and neoabyssomicin B (3) were isolated from the crude ethyl acetate extract of the endophytic Streptomyces sp. fermentation culture using sem-preparative HPLC. The chemical structures of the compounds were established using 1D and 2D NMR, HRESIMS, UV, ECD, and by comparison to published data. This work represents the first study of an endophyte obtained from the liverwort B. trilobata, and the first report of isolated metabolites from a liverwort-associated endophytic bacterium. The discovery of abyssomicins from this unique microbial source broadens the known ecological and taxonomic distribution of these compounds. The production of known antibacterial metabolites by an endophytic bacterium may have implications for microbial interactions within the liverwort. Additionally, this study discusses the distribution pattern of known abyssomicins across different bacterial genera, highlighting the distinct biosynthetic origins of these compounds.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105077"},"PeriodicalIF":1.4,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144596080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytotoxic stilbenoid from the leaves and stems of Cassia nodosa 决明子叶和茎的细胞毒性二苯乙烯类化合物

IF 1.4 4区生物学

Biochemical Systematics and Ecology Pub Date : 2025-07-08 DOI: 10.1016/j.bse.2025.105081

Qionghui Sun , Limei Yu , Changyan Shao , Chen Qing , Haji Akber Aisa , Rui Zhan , Yegao Chen

{"title":"Cytotoxic stilbenoid from the leaves and stems of Cassia nodosa","authors":"Qionghui Sun , Limei Yu , Changyan Shao , Chen Qing , Haji Akber Aisa , Rui Zhan , Yegao Chen","doi":"10.1016/j.bse.2025.105081","DOIUrl":"10.1016/j.bse.2025.105081","url":null,"abstract":"<div><div>One new stilbene, trans-3,2′-dihydroxy-3′,4′,5-trimethoxy stilbene (1), together with seven known ones (2–8) were isolated from the leaves and stems of Cassia nodosa Buch.-Ham. ex Roxb (Fabaceae). The structure of the new compound was elucidated via analyses of NMR (1 D and 2 D) and HRESIMS data. To the best of our knowledge, all the known compounds were isolated from the genus Cassia for the first time. Cytotoxicity and anti-neuroinflammatory activities assay of the isolated compounds revealed that 1 exhibited significant cytotoxicity superior to the positive control cisplatin against MDA-MB-231 and MCF-7 cell lines. Furthermore, the chemotaxonomic significance of the isolates was also discussed, building upon our previous studies on flavonoids, anthraquinones, terpenoids, and flavan derivatives from C. nodosa, which collectively enrich the phytochemical profile of this species and support its classification within the genus Cassia.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105081"},"PeriodicalIF":1.4,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144572558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0