AbdElAziz El Taweel, Rehab Salem, O. El-Shimi, Fatma Abdalla
{"title":"Insulin Resistance in Patients with Androgenic Alpoecia”","authors":"AbdElAziz El Taweel, Rehab Salem, O. El-Shimi, Fatma Abdalla","doi":"10.21608/bjas.2023.241783.1267","DOIUrl":"https://doi.org/10.21608/bjas.2023.241783.1267","url":null,"abstract":"Background: Androgenic Up to half of men and females are susceptible to androgenetic alopecia (AGA), a genetically determined condition caused by an overreaction to androgens. The loss of scalp hair in male-pattern baldness is related to androgen metabolism and the hair development cycle, both of which insulin is thought to regulate (Nabaie et al., 2009). We found significant differences in insulin, glucose, and HOMA-IR between the patients and controls when we defined hyperinsulinaemia as a fasting serum insulin level of > 10 U/mL. Androgenic alopecia patients had elevated insulin, glucose, and HOMA-IR compared to healthy individuals. This shows that individuals with androgenic alopecia may have unique metabolic profiles, which points to possible underlying mechanisms in the aetiology and evolution of AGA. Based on our findings, we know that HOMA-IR is positively correlated with insulin levels, and that a higher HOMA-IR is strongly linked to being female.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139315717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preliminary Outcomes of Base Metacarpal Fractures Surgical Management","authors":"Emad Esmat, Eslam Tabl, Samir Monib, Ahmed EL DIN","doi":"10.21608/bjas.2023.232964.1239","DOIUrl":"https://doi.org/10.21608/bjas.2023.232964.1239","url":null,"abstract":"Background: Base Surgery for metacarpal fractures is complicated by the wide variety of treatment options. This research fills a gap in the literature by contrasting the two treatment options for unstable base metacarpal fractures: fixation and temporary arthrodesis. Methods Patients with closed metacarpal fractures who satisfied certain criteria participated in this randomised experiment at a university hospital. Subjects were randomly allocated to either Group A (fixation methods) or Group B. (temporary arthrodesis). Information about the patients' demographics, preoperative evaluations, surgical procedures, and recovery schedules were documented. Subjective and objective ratings, imaging studies, and objective assessments of function all contributed to the final tally. FindingsFifteen participants were included in the research overall. The two groups were similar to one another demographically. Differences emerged between the groups with respect to the length of the operation, the quantity of C-arm pictures, and the time it took to achieve union. Total Active Motion (TAM) and other objective evaluation indicators showed that both groups performed similarly. The occurrence of complications was similar across the two groups. Results from treating unstable base metacarpal fractures with either fixation or temporary arthrodesis were positive, the authors write. The two groups were comparable in terms of demographics, postoperative functional evaluations, and complication rates.roups.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139325299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Hamed, Ghada Mohamed, Hend Nasr, Eman Abdulaziz
{"title":"Serum Clusterin Level in with Post Adolescent Acne","authors":"Ahmed Hamed, Ghada Mohamed, Hend Nasr, Eman Abdulaziz","doi":"10.21608/bjas.2023.237325.1255","DOIUrl":"https://doi.org/10.21608/bjas.2023.237325.1255","url":null,"abstract":"","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139330151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Abdallah, Hesham khaled, Al-Shimaa Mohamed, Basant Mohammad
{"title":"Impact of Early Adulthood Obesity on Left and Right Ventricular Function (An Echocardiographic Study)”","authors":"Ahmed Abdallah, Hesham khaled, Al-Shimaa Mohamed, Basant Mohammad","doi":"10.21608/bjas.2023.234076.1241","DOIUrl":"https://doi.org/10.21608/bjas.2023.234076.1241","url":null,"abstract":"The Worldwide rates of obesity, particularly among children and young adults, are Increasing. Heart failure, coronary disease, and peripheral vascular disease have all been linked to obesity, and the incidence of their consequences has also been found to fluctuate accordingly. Obese patients often exhibit early signs of heart failure, including subclinical left ventricular dysfunction.The aim of this study was to determine the effect of early age obesity on left and right ventricular functions using echocardiography. 75 healthy volunteers were included in our study who presented to Department of cardiovascular medicine at benha university hospitals in the period between July 2022 to May 2023. All volunteers were evaluated using Echocardiography at Benha University Hospital's Cardiology department and divided into two groups. Group I (control) consisted of participants with a body mass index (BMI) of 25 or less (non-obese), while Group 2 (Case) consisted of participants with a BMI of 30 or more (Obese). Heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) showed no statistically significant differences between the groups. There were no statistically significant variations in PWTd across the groups. Mitral E wave velocity, Mitral A wave velocity, and the E/A ratio showed no statistically significant differences between groups. Obese group had a greater IVSd than the control group.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139332663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
rania anwar, Nancy W. Mikhael, Ghada M. Abdel-Khalek, Inas A. Elsayed
{"title":"salivary calprotectin level in patients with oral lichen planus","authors":"rania anwar, Nancy W. Mikhael, Ghada M. Abdel-Khalek, Inas A. Elsayed","doi":"10.21608/bjas.2023.233859.1242","DOIUrl":"https://doi.org/10.21608/bjas.2023.233859.1242","url":null,"abstract":"Objectives: assessment the concentration of calprotectin in the saliva of patients with oral lichen planus compared to healthy individuals and its relation with severity of the disease . Background: Calprotectin, a calcium-binding protein, is a key player in the pathogenesis of numerous inflammatory diseases, such as psoriasis and acne vulgaris. However, it has not been well studied in patients with oral lichen planus. Data Sources: By searching and reviewing Medline databases (Pub Med and Medscape) and looking for studies that examined the possible role of calprotectin in patients with oral lichen planus available till 2022. Study Selection: We independently reviewed all studies to determine if they met our criteria for inclusion. We included studies that met the following criteria;1.Written and published in English language. 2. Published in peer-reviewed journals.3.Explain how the level of salivary calprotectin may be linked to oral lichen planus and how it may affect severity of the disease . Data Extraction: Studies that did not meet our criteria were excluded from our review. We assessed the quality of the studies based on whether they had ethical approval, specified eligibility criteria, used appropriate controls, and provided adequate information and well-defined evaluation measures. We used a data collection form to independently extract data from each eligible study, focusing on the outcomes that were relevant to our study. Conclusions: Salivary calprotectin level is increased in patients with oral lichen planus compared to healthy control subjects","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139331626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tri-malleolar Ankle Fractures: Trans-syndesmotic Versus Posterior Malleolar Fixation","authors":"M. Hegazy, Ahmed R. Zakaria, Mohamed Mounir","doi":"10.21608/bjas.2023.232705.1238","DOIUrl":"https://doi.org/10.21608/bjas.2023.232705.1238","url":null,"abstract":"Background: Trimalleolar fractures are often referred to as posterior malleolar fractures and have been the subject of continuing interest for a long time as one of the most controversial issues of the treatment of ankle injuries. The aim of this work was to evaluate the effect of posterior malleolus fractures direct reduction and internal fixation on syndesmotic injuries reduction, compared to the direct syndesmotic fixation in trimalleolar ankle fractures, on the functional and short radiological outcomes. Methods: This was a prospective randomized comparative study on the effect of posterior malleolus fractures reduction and internal fixation on syndesmotic injuries reduction, compared to the direct syndesmotic fixation in trimalleolar ankle fractures, on the functional and short radiological outcomes. Patients were divided into two equal groups: Group A: 15 patients with Posterior malleolar fracture left with no direct reduction and internal fixation and group B: 15 patients with posterior malleolar fragment that was fixed directly by screw or plate and screw. 1 case was excluded from group due to open syndesmosis during cotton test intraoperatively during fixing of posterior malleolus, so the patient needed trans syndesmotic screw. Results: Operative duration was significantly lower in group A than group B (p <0.001). Regarding the potential complications of procedures in groups A and B, infection occurred in only 1 (6.67%) patient in group B and didn’t occur in group A, and mechanical irritation occurred in only 1 (6.67%) patient in group A and didn’t occur in","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139331781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of pediatric genu varum by temporary hemiepiphysiodesis using 8-shaped plate","authors":"Adel Adawy, Mohamed Meselhy, Abdallah Eliwa","doi":"10.21608/bjas.2023.232642.1237","DOIUrl":"https://doi.org/10.21608/bjas.2023.232642.1237","url":null,"abstract":"Background: Genu varum, a common juvenile orthopaedic disease, may cause gait problems and functional difficulties. Hemiepiphysiodesis using an 8-shaped plate is a new technique, although its clinical and radiological results need study. This research examined the clinical and radiological outcomes of hemiepiphysiodesis with 8-shaped plate for juvenile genu varum. Methods: Thirty children aged 3–15 with genu varum were investigated antegrade and retrogradely. The patients had clinical, radiological, and laboratory tests before surgery. Under general anaesthesia, patients were examined for operation time, intraoperative and postoperative problems, radiological follow-up, and hospital stay. Final follow-up was six months following surgery. Results: The research group had a mean age of 6.6 years and 43 percent females and 57 percent men. Correction was done bilaterally (7%), left (10%), and right (13%), targeting femur and tibia (50%) or femur just (10%) or tibia only (40 percent ). Mean hospitalisation was 0.8 days, and average correction was 10.6 months. Surface infections (7%), LIMITED ROM (10%), and damaged screws (3%) were the only difficulties, with 80% with no issues. Rebound correlates with complications. Intercondylar distance, mechanical axis deviation, proximal tibial angle, and distal femoral angle improved significantly. Logistic regression did not find rebound or complications risk variables. Conclusions: 8-plate insertion is a successful therapy for genu varum in children, although rebound and complications must be monitored.ssary.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"238 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139334876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sherine Ahmed, Ghada Mohamed, Amira Abd El-Ghafar, Hanaa Taha
{"title":"Evaluation of Serum Urocortin 3 in acne vulgaris patients","authors":"Sherine Ahmed, Ghada Mohamed, Amira Abd El-Ghafar, Hanaa Taha","doi":"10.21608/bjas.2023.234112.1243","DOIUrl":"https://doi.org/10.21608/bjas.2023.234112.1243","url":null,"abstract":"Background: Acne vulgaris is a prevalent skin disorder characterized by various inflammatory lesions. The pathogenesis of acne involves complex interplays of multiple factors, including increased sebum production, inflammation, and immune responses. Urocortin 3 (UCN 3), a neuropeptide with diverse physiological functions, has been implicated in skin barrier function and immune modulation. However, its role in acne vulgaris remains poorly understood. Objective: This descriptive review aims to provide an overview of UCN 3, explore its known physiological functions, elucidate the pathogenesis of acne vulgaris, and discuss the multifactorial nature of acne development, considering genetic, environmental, and lifestyle factors. Conclusions: The reviewed literature indicates that Urocortin 3 (UCN 3) holds potential implications in acne pathogenesis, as evidenced by its presence in acne-affected skin and altered serum levels in acne patients. Its known physiological functions in stress regulation, inflammation, and immune responses suggest possible roles in acne development and severity. While specific mechanisms remain unclear, exploring UCN 3's interactions with known acne-related pathways may unveil novel therapeutic targets for acne management.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139334901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Postoperative confusion after anasthesia in elderly patients with femoral neck fracture","authors":"Ehab Afifi, Amany Fekry, Soaad Abo El-Wafa","doi":"10.21608/bjas.2023.231186.1234","DOIUrl":"https://doi.org/10.21608/bjas.2023.231186.1234","url":null,"abstract":"Background: Confusion, a One of the most prevalent issues in medicine is a mental and behavioural condition of diminished understanding, coherence, and ability for reason. The acute confusional condition known as delirium continues to be a leading cause of morbidity and death worldwide. There may be neurological predisposing variables when some older persons of the same age have the same procedure and others do not suffer postoperative delirium. Objectives: The purpose of this research was to evaluate the impact of anaesthesia on cognitive function in elderly individuals with femoral neck fracture. Conclusions: Delirium after hip fracture surgery is a frequent but dangerous complication. Metabolic dysfunction, drug-related issues, stress reactions, and anaesthetic type are all possible contributors. Interventions like anxiety reduction and pharmaceutical medications may be useful, but there is no one-size-fits-all approach to prevention.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"166 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139334846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidence of Early Onset Neonatal Acute Kidney Injury in the NICU of Benha University hospital","authors":"Hana Omar, Mohamed Abdelbaki, Houda Rabbany","doi":"10.21608/bjas.2023.234348.1244","DOIUrl":"https://doi.org/10.21608/bjas.2023.234348.1244","url":null,"abstract":"Background: Neonatal Acute Kidney Injury (AKI) is a critical concern in neonatal intensive care units (NICUs), impacting morbidity and mortality. Early identification of AKI and its risk factors is crucial for improved neonatal care. This study aimed to identify the incidence, predisposing factors, clinical features of AKI in neonates admitted in NICU. Methods: A total of 200 neonates out of 570 cases attending the outpatient clinic were enrolled in the study. Clinical information, maternal medical history, examination findings, laboratory parameters, and medication exposures were collected and analyzed. The KDIGO workgroup definition was adapted to define neonatal AKI. Results : Among neonates, 45.0% developed AKI. Gender and gestational age showed no significant differences between AKI and non-AKI groups. Birth weight below 1000g was associated with AKI (p = 0.03). Neonates with AKI were more likely to receive aminoglycosides and vancomycin (p < 0.001), exhibit oliguric urine output (p < 0.001), and have hypertensive blood pressure levels (p < 0.001). Higher CRP levels (p = 0.002), total leukocyte count (TLC) (p = 0.002), and hemoglobin levels (p = 0.04) were observed in the AKI group. Additionally, sodium and potassium imbalances (p < 0.001) and metabolic acidosis (p < 0.001) were prevalent in AKI cases. Conclusion: This study showed the effect of birth weight, medication exposure, and clinical markers on AKI development. Elevated C-reactive protein levels and blood parameter imbalances serve as important risk indicators","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139335685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}