Beyoglu Eye Journal最新文献

{"title":"Comparison of the Accuracy, Comprehensiveness, and Readability of ChatGPT, Google Gemini, and Microsoft Copilot on Dry Eye Disease.","authors":"Dilan Colak, Burcu Yakut, Abdullah Agin","doi":"10.14744/bej.2025.76743","DOIUrl":"https://doi.org/10.14744/bej.2025.76743","url":null,"abstract":"<p><strong>Objectives: </strong>This study compared the performance of ChatGPT, Google Gemini, and Microsoft Copilot in answering 25 questions about dry eye disease and evaluated comprehensiveness, accuracy, and readability metrics.</p><p><strong>Methods: </strong>The artificial intelligence (AI) platforms answered 25 questions derived from the American Academy of Ophthalmology's Eye Health webpage. Three reviewers assigned comprehensiveness (0-5) and accuracy (-2 to 2) scores. Readability metrics included Flesch-Kincaid Grade Level, Flesch Reading Ease Score, sentence/word statistics, and total content measures. Responses were rated by three independent reviewers. Readability metrics were also calculated, and platforms were compared using Kruskal-Wallis and Friedman tests with <i>post hoc</i> analysis. Reviewer consistency was assessed using the intraclass correlation coefficient (ICC).</p><p><strong>Results: </strong>Google Gemini demonstrated the highest comprehensiveness and accuracy scores, significantly outperforming Microsoft Copilot (p<0.001). ChatGPT produced the most sentences and words (p<0.001), while readability metrics showed no significant differences among models (p>0.05). Inter-observer reliability was highest for Google Gemini (ICC=0.701), followed by ChatGPT (ICC=0.578), with Microsoft Copilot showing the lowest agreement (ICC=0.495). These results indicate Google Gemini's superior performance and consistency, whereas Microsoft Copilot had the weakest overall performance.</p><p><strong>Conclusion: </strong>Google Gemini excelled in content volume while maintaining high comprehensiveness and accuracy, outperforming ChatGPT and Microsoft Copilot in content generation. The platforms displayed comparable readability and linguistic complexity. These findings inform AI tool selection in health-related contexts, emphasizing Google Gemini's strengths in detailed responses. Its superior performance suggests potential utility in clinical and patient-facing applications requiring accurate and comprehensive content.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"10 3","pages":"168-174"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Serum Vitamin and Mineral Levels in Benign Essential Blepharospasm: A Comparative Study.","authors":"Burcu Yakut, Anilcan Atac, Ahu Yilmaz, Feyza Onder","doi":"10.14744/bej.2025.92260","DOIUrl":"https://doi.org/10.14744/bej.2025.92260","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare serum levels of folic acid, Vitamin B12, 25-hydroxy (OH) Vitamin D, calcium (Ca), zinc (Zn), phosphorus, and magnesium (Mg) between patients with benign essential blepharospasm (BEB) and healthy controls and to examine their associations with disease severity and frequency.</p><p><strong>Methods: </strong>A retrospective study was conducted on 20 patients with BEB (13 females, 7 males) and 25 healthy controls (15 females, 10 males) from our clinic. Serum levels of folic acid, Vitamin B12, 25-OH Vitamin D, Ca, phosphorus, Mg, and Zn, as well as ophthalmologic examination results, were analyzed. BEB severity and frequency were assessed using the Jankovic Rating Scale (0-4).</p><p><strong>Results: </strong>Serum levels of Vitamin B12, folic acid, Zn, Ca, phosphorus, and Mg were within normal limits for both groups. However, serum Vitamin D levels were below normal in both groups. No significant differences were found between the BEB and control groups regarding serum Vitamin B12, 25-OH Vitamin D, Ca, phosphorus, Mg, and Zn levels (p>0.05). Notably, serum folic acid levels were significantly lower in the BEB group compared to controls (6.19±2.75 vs. 8.95±4.10, p=0.011). In addition, a significant negative correlation was observed between serum folic acid levels and Jankovic severity (r=-0.378, p=0.011) and frequency scores (r=-0.392, p=0.008).</p><p><strong>Conclusion: </strong>These findings suggest that folic acid may play a role in BEB pathogenesis. Further studies are needed to explore the underlying mechanisms and potential benefits of micronutrient supplementation in BEB management.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"10 3","pages":"149-153"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Health Tourism and Corneal Refractive Surgery: Insights From a Single Referral Center.","authors":"Yusuf Berk Akbas, Ahmet Alperen Koc","doi":"10.14744/bej.2025.41713","DOIUrl":"https://doi.org/10.14744/bej.2025.41713","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this study was to compare the characteristics, clinical outcomes, and complications of health tourism patients who underwent corneal refractive surgery with the local patient group.</p><p><strong>Methods: </strong>This retrospective study analyzed the medical records of 736 health tourism patients and 853 local patients who presented for corneal refractive surgery. Patient demographics, type of laser procedure, visual and refractive outcomes, complications, and follow-up period were recorded.</p><p><strong>Results: </strong>The mean ages of health tourism patients and local patients were 27.1±5.9 and 26.3±5.3 (p=0.216), respectively. The percentage of patients who underwent surgery was significantly higher among health tourism patients (91.0%) compared to local patients (78.2%) (p<0.01). There were no significant differences in uncorrected distance visual acuity, corrected distance visual acuity, or spherical equivalent at the 3-month post-operative examination. The median follow-up period for health tourism patients was 1 (1-360) day, while for local patients, it was 360 (30-1080) days (p<0.001). The percentage of patients who received laser-assisted <i>in situ</i> keratomileusis surgery was significantly higher in the health tourism group (89.9% vs. 82.0%, p<0.001). There were no significant differences in perioperative or early post-operative complications.</p><p><strong>Conclusion: </strong>Health tourism patients were more likely to have undergone surgery and had a significantly shorter follow-up period. This may particularly affect the follow-up of the long-term complications.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"10 3","pages":"154-158"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Swept-Source Optical Coherence Tomography and Optical Coherence Tomography Angiography Findings in Patients with Solar Retinopathy.","authors":"Erkut Kucuk, Huseyin Yesilyurt, Kursad Ramazan Zor, Omer Ozer, Muge Coban Karatas","doi":"10.14744/bej.2025.93206","DOIUrl":"https://doi.org/10.14744/bej.2025.93206","url":null,"abstract":"<p><strong>Objectives: </strong>Solar retinopathy is a retinal disease caused by exposure to ultraviolet radiation from sunlight, primarily affecting the outer retinal layers, including photoreceptors and the retinal pigment epithelium. This cross-sectional study aimed to present the optical coherence tomography (OCT) and OCT angiography (OCTA) findings in patients with solar retinopathy.</p><p><strong>Methods: </strong>Fourteen eyes from 11 patients with a history of solar exposure during a partial solar eclipse were included. OCT and OCTA were performed and parameters including central macular and choroidal thickness, outer retinal defect thickness, retinal pigment epithelium (RPE)-Bruch membrane thickness, outer retinal defect area on en face OCT, OCTA foveal avascular zone area, and vessel density in the central fovea were measured. Their correlation with the visual acuity (VA) was investigated.</p><p><strong>Results: </strong>Hyporeflective outer retinal defects including the ellipsoid and interdigitation zones were observed in all eyes in B scan and en face structural OCT. OCTA indicated a normal vascular pattern with no choriocapillaris flow deficits corresponding to the outer retinal defects. A significant positive correlation was found between VA and RPE-Bruch membrane thickness under the outer retinal defect. There was no significant relationship between VA and other OCT and OCTA parameters.</p><p><strong>Conclusion: </strong>The outer retina is affected in solar retinopathy. En face structural OCT enables the measurement of the area of outer retinal defect. The significant relationship between VA and RPE-Bruch membrane thickness suggests that this may be an indicator of severity.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"10 3","pages":"127-133"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selenium: Could It Be the Game-Changer for Ocular Surface and Anterior Chamber in Graves' Disease?","authors":"Pelin Kiyat, Gokcen Semiz","doi":"10.14744/bej.2025.38700","DOIUrl":"https://doi.org/10.14744/bej.2025.38700","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effects of selenium supplementation on ocular surface parameters and anterior segment architecture in euthyroid Graves' disease (GD) patients without ophthalmopathy.</p><p><strong>Methods: </strong>This cross-sectional study included 218 consecutive euthyroid GD patients without clinical manifestations of Graves' ophthalmopathy (GO). Patients underwent comprehensive ophthalmological examination, including the Ocular Surface Disease Index (OSDI) questionnaire, tear film break-up time (T-BUT), Oxford scale scoring, and Pentacam Scheimpflug imaging for anterior segment parameters assessment. Selenium intake was questioned, and based on selenium intake, participants were divided into two groups: the selenium intake group (n=106), receiving selenium supplementation (100 µg twice daily for 6 months) with standard anti-thyroid therapy, and the control group (n=112), receiving only standard anti-thyroid therapy.</p><p><strong>Results: </strong>The mean age was 45.7±7.8 years (range: 30-61) in the selenium intake group (n=106; 48 females, 58 males) and 46.1±7.5 years (range: 30-60) in the control group (n=112; 52 females, 60 males), with no significant difference between groups (p=0.821 for age, p=0.904 for gender distribution). The mean duration of selenium supplementation was 11.4±4.2 months. The selenium group showed significantly better ocular surface parameters, with lower OSDI scores and higher T-BUT values compared to the control group (p<0.001 for both). Oxford staining scores were lower in the selenium group, though not statistically significant (p=0.244). Pentacam analysis revealed significantly higher anterior chamber volume (p=0.024) and central corneal thickness (p<0.001) in the selenium group, while anterior chamber depth and angle width were higher but not statistically significant (p=0.322 and p=0.276, respectively).</p><p><strong>Conclusion: </strong>Selenium supplementation is associated with better ocular surface parameters and different anterior segment architecture in euthyroid GD patients without ophthalmopathy. Clinical associations observed in these cases may be related to selenium's antioxidant and anti-inflammatory properties through glutathione peroxidase and thioredoxin reductase activity, suggesting selenium as a potentially beneficial therapeutic approach for ocular surface integrity in GD.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"10 3","pages":"181-187"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of Retinopathy of Prematurity Between 2021 and 2024: Results from a Single Center.","authors":"Osman Kizilay, Serap Karaca, Bilge Batu Oto, Gokhan Celik","doi":"10.14744/bej.2025.21549","DOIUrl":"https://doi.org/10.14744/bej.2025.21549","url":null,"abstract":"<p><strong>Objectives: </strong>Retinopathy of prematurity (ROP) is a multifactorial disease characterized by abnormal vascularization of the immature retina. Although the most important risk factors are gestational age (GA) and birth weight (BW), the quality of neonatal intensive care also affects its incidence. This study aimed to evaluate the incidence of ROP and the need for treatment in infants screened for ROP according to the 2021 Turkish Prematurity Screening Guidelines for Retinopathy.</p><p><strong>Methods: </strong>Records of premature babies screened for ROP at a single center between January 2021 and December 2024 were retrospectively evaluated. The results of the examinations, need for treatment, and hospital centers where premature infants were examined in accordance with the new guidelines were recorded.</p><p><strong>Results: </strong>Between 2021 and 2024, 8,503 premature infants were screened for ROP at our clinic. A total of 1,623 infants were diagnosed with ROP, and 147 were treated using either laser photocoagulation or intravitreal bevacizumab. The number of babies with a BW over 1,700 g who were screened for ROP was 6,581; of these, 738 (11.21%) developed ROP, and 28 babies (0.42%) were treated. The number of babies born at ≥34 weeks' GA and who were screened for ROP was 4,029; of these, 173 (4.29%) developed ROP, and one baby (0.024%) was treated. Among the 1,623 patients diagnosed with ROP, 147 were treated, and 1,476 had spontaneously regressed ROP.</p><p><strong>Conclusion: </strong>Significant ROP requiring treatment may occur in infants born at >34 weeks of gestation and/or with a BW ≥1,700 g.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"10 3","pages":"142-148"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Depth of the Stromal Demarcation Line and Clinical Outcomes in Corneal Crosslinking Treatment with Hydroxypropyl Methylcellulose-Based and Vitamin E-TPGS-Based Riboflavin Solutions.","authors":"Hafize Gokben Ulutas, Ayse Balikci Tufekci","doi":"10.14744/bej.2025.23434","DOIUrl":"https://doi.org/10.14744/bej.2025.23434","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare the visual and topographic results and the depth of demarcation line in patients who underwent epithelial-off-cross-linking (CXL) with riboflavin solutions containing D alpha-tocopheryl polyethylene-glycol 1000 succinate (Vitamin E-TPGS) and 1.1% hydroxypropyl methylcellulose (HPMC).</p><p><strong>Methods: </strong>Patients with progressive keratoconus, 26 treated with HPMC (Group 1) and 34 treated with Vitamin E-TPGS (Group 2), were evaluated retrospectively. Best corrected visual acuity, spherical equivalent, refractive cylinder, and corneal topography parameters (keratometry of flat and steep meridians (K1 and K2), maximum keratometry (Kmax), central, thinnest, and apical corneal thickness) at baseline and post-operative follow-up visits were compared (1, 3, 6, and 12 months). Corneal stromal demarcation line depth (DLD) was measured centrally, nasally, and temporally (1.5 mm and 3 mm distance from the center of the cornea) by anterior segment optical coherence tomography at 1 month post-operatively, and changes in endothelial cell density (ECD) at 6 months were compared between the two groups.</p><p><strong>Results: </strong>There was no difference between the two groups in terms of age and gender. The mean DLD was deeper in group 1 (325.95±76.55 µm) than in group 2 (267.94±54.2 µm) (p=0.002). In the 3^rd month, K1, K2, and Kmax changes, while a decrease was observed in Group 1 compared to the baseline; an increase was observed in Group 2 (all p<0.05). At the end of the 1 year, K1, K2, and Kmax were decreased in both groups. There was no difference in ECD change between baseline and 6 months in both riboflavin solutions (p=0.12).</p><p><strong>Conclusion: </strong>HPMC-based riboflavin appears to be associated with a deeper demarcation line than Vitamin E-TPGS-based riboflavin. While a decrease in K values was observed in the earlier period in HPMC, no difference was observed between Vitamin E-TPGS and HPMC at the 12^th month in terms of efficacy. Both riboflavin solutions were safe for the endothelium.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"10 3","pages":"159-167"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Detector Analysis for the Identification of Academic Articles Synthesized by Artificial Intelligence in the Field of Ophthalmology.","authors":"Sebnem Kaya Ergen","doi":"10.14744/bej.2025.70973","DOIUrl":"https://doi.org/10.14744/bej.2025.70973","url":null,"abstract":"<p><strong>Objectives: </strong>The increasing use of large language models, such as ChatGPT, in academic writing has raised significant ethical concerns within the academic community. This study explores the potential challenges posed by the ability of artificial intelligence (AI) to produce realistic, evidence-based academic texts and investigates whether these challenges can be effectively controlled.</p><p><strong>Methods: </strong>Three original articles in the field of ophthalmology were provided as input to ChatGPT-4o to generate introduction sections. A total of 50 introduction texts were synthesized from 150 original articles. These AI-generated texts were analyzed using AI detectors (GPTZero, Writer, CorrectorApp, and ZeroGPT) and a plagiarism detector. In addition, the ability of AI detectors to differentiate between original and AI-generated texts was evaluated.</p><p><strong>Results: </strong>There was a statistically significant difference in AI detector probabilities between original and AI-generated texts (p<0.001 for all detectors). GPTZero demonstrated a sensitivity of 100% and a specificity of 96% in distinguishing original from AI-generated texts, outperforming all other AI detectors. However, paraphrased AI-generated texts significantly reduced the detection accuracy of GPTZero (p<0.001).</p><p><strong>Conclusion: </strong>ChatGPT-4o demonstrated the ability to synthesize new texts with referenced citations within seconds, capable of bypassing plagiarism detectors. However, AI detectors showed limitations in achieving absolute accuracy and occasionally misclassified original texts. Even with the most accurate AI detectors, a simple paraphrasing method significantly compromised prediction accuracy, highlighting the need for improved detection strategies and ethical oversight.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"10 3","pages":"175-180"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Localized Conjunctival Amyloidosis Mimicking Lymphoma.","authors":"Betul Coskun, Esra Ucaryilmaz Ozhamam, Nilay Yuksel","doi":"10.14744/bej.2025.25991","DOIUrl":"https://doi.org/10.14744/bej.2025.25991","url":null,"abstract":"<p><p>A 27-year-old healthy male presented to our clinic with complaints of redness and burning in his left eye for the past 6 months. Biomicroscopic examination revealed a salmon-colored, elevated, painless mass lesion involving the entire lower fornix conjunctiva of the left eye. A conjunctival incisional biopsy was performed due to suspicion of lymphoproliferative disease. Histopathological examination confirmed amyloidosis. Further investigations did not reveal any evidence of systemic amyloidosis, lymphoma, or other lymphoproliferative diseases. During the 18-month follow-up after surgery, no recurrence or new findings were observed in the patient's ophthalmologic or systemic evaluations. Amyloidosis in the periocular region can present with various clinical findings. Although a classic salmon-colored conjunctival mass initially may suggest lymphoproliferative diseases, conjunctival amyloidosis should be considered in the differential diagnosis.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"10 3","pages":"188-193"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of Laser Hyaloidotomy in Premacular Hemorrhage: Identifying Predictors of Treatment Success and Need for Vitrectomy.","authors":"Ramesh Venkatesh, Vishma Prabhu, Prathibha Hande, Karishma Tendulkar","doi":"10.14744/bej.2025.04809","DOIUrl":"https://doi.org/10.14744/bej.2025.04809","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the outcomes of laser hyaloidotomy (LH) in treating premacular hemorrhage (PMH) and identify factors influencing treatment success.</p><p><strong>Methods: </strong>In this retrospective cohort study, patients with PMH of any etiology treated with LH were included. Patient demographics and PMH characteristics were documented. Treatment efficacy was assessed based on successful hyaloid puncture, blood drainage into the vitreous cavity, and the need for pars plana vitrectomy (PPV).</p><p><strong>Results: </strong>A total of 56 eyes from 51 patients (36 males, 15 females; mean age: 46.32±15.07 years) underwent LH for PMH (all cases had subhyaloid hemorrhage). The median symptom duration was two days (range: 0-30 days). The mean time interval between advising and performing LH was 4.92±12.82 days. Pretreatment visual acuity ranged from counting fingers to 6/36. LH was successful in 14 eyes (25%), while 42 eyes (75%) failed, primarily due to non-drainage of PMH (32 eyes, 76%) or persistent vitreous hemorrhage (10 eyes, 24%). PMH secondary to proliferative diseases universally requires PPV. PMH located within the retinal arcades or closer to the presumed fovea was more likely to necessitate PPV (p=0.001).</p><p><strong>Conclusion: </strong>LH demonstrated limited efficacy, particularly in PMH associated with proliferative diseases or in those confined within the inferior retinal arcade. These cases frequently required early PPV. Incorporating vitrectomy into the initial treatment strategy may optimize outcomes for specific PMH subgroups.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"10 3","pages":"134-141"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}