Beyoglu Eye Journal最新文献

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3D-Printed Placido Disc for Intraoperative Keratoscopy. 用于术中角膜镜检查的 3D 打印 Placido 盘。
Beyoglu Eye Journal Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.14744/bej.2024.30643
Ali Devebacak, Cumali Degirmenci, Melis Palamar
{"title":"3D-Printed Placido Disc for Intraoperative Keratoscopy.","authors":"Ali Devebacak, Cumali Degirmenci, Melis Palamar","doi":"10.14744/bej.2024.30643","DOIUrl":"10.14744/bej.2024.30643","url":null,"abstract":"","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"9 2","pages":"59-60"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the H-Indexes of Editorial Board Members in Ophthalmology Journals Published in Türkiye. 评估在土耳其出版的眼科期刊中编委会成员的 H 指数。
Beyoglu Eye Journal Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.14744/bej.2024.03030
Murat Erdag, Mehmet Citirik
{"title":"Assessing the H-Indexes of Editorial Board Members in Ophthalmology Journals Published in Türkiye.","authors":"Murat Erdag, Mehmet Citirik","doi":"10.14744/bej.2024.03030","DOIUrl":"10.14744/bej.2024.03030","url":null,"abstract":"<p><strong>Objectives: </strong>The focus of this study was to assess and compare the h-indexes of editorial board members from eight ophthalmology journals in Türkiye and explore the potential correlations between these indexes and the sub-specialties of board members.</p><p><strong>Methods: </strong>Conducted in December 2023, this cross-sectional study utilized publicly available data from Google Scholar (GS), Web of Science, and Scopus. The h-index and number of publications by editorial board members from eight Turkish ophthalmology journals were analyzed. Statistical analysis for this study involved the use of SPSS, employing descriptive statistics, one-way analysis of variance, and <i>post hoc</i> tests for group comparisons.</p><p><strong>Results: </strong>Of the 415 editorial board members, 26 were not ophthalmologists and 12 worked abroad; the credentials of 10 could not be verified. A total of 367 authors were evaluated, revealing significant differences in publication numbers and h-indices among the different subspecialties. Notably, the retinal specialists demonstrated higher productivity. Variability in citation counts was observed across databases, with GS having the widest range. Differences were also noted in the publication and h-index among the editorial boards of different journals.</p><p><strong>Conclusion: </strong>The h-index and number of publications effectively reflected the active status of ophthalmology authors. This study contributes valuable information regarding Turkish ophthalmology journals and their editorial boards, serving as an inspiration for young ophthalmologists. These findings underscore the diverse successes of ophthalmologists across subspecialties, encouraging the exploration of less-explored areas in academic pursuits.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"9 2","pages":"101-105"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intracerebral Hemorrhage Manifesting as Optic Aphasia: A Case Report. 表现为视失语症的脑内出血:病例报告。
Beyoglu Eye Journal Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.14744/bej.2024.43765
Christopher Andrean Putra Johansyah, Leliana Bambang
{"title":"Intracerebral Hemorrhage Manifesting as Optic Aphasia: A Case Report.","authors":"Christopher Andrean Putra Johansyah, Leliana Bambang","doi":"10.14744/bej.2024.43765","DOIUrl":"10.14744/bej.2024.43765","url":null,"abstract":"<p><p>Optic aphasia is a rare neurological disorder that affects the visual-semantic ability of patients with normal vision and is caused by a lesion in the left occipital lobe. The signs and symptoms of optic aphasia are similar to those of associative visual agnosia, where patients have difficulty recognizing objects both in shape and function, resulting in challenges performing daily tasks. The transformation to optic aphasia or associative visual agnosia is closely related to the degree of damage to the corpus callosum, with some studies hypothetically suggesting that complete damage to the corpus callosum leads to optic aphasia, whereas incomplete damage causes associative visual agnosia. We present a case of a 60-year-old man with a history of intracerebral hemorrhage in the left occipitotemporoparietal lobe. The patient complained of intermittent episodes of painless, blurry vision. Upon examination, we observed that the patient was unable to read the Snellen chart, although he could draw the letter. Furthermore, we discovered that the patient had difficulty naming objects and instruments, even though he was able to express their shape and function through gestures and mimicry. The signs and symptoms of the patient, along with the result of the multi-slice non-contrast CT scan, suggest that he had optic aphasia rather than associative visual agnosia. A comprehensive neuropsychological and aphasia examination needs to be performed to further assess the condition of our patient and establish the diagnosis.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"9 2","pages":"109-113"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Anxiety, Depression, Self-Esteem, and Quality-of-Life in Patients Undergoing Surgical Removal of an Eye. 评估眼球摘除手术患者的焦虑、抑郁、自尊和生活质量。
Beyoglu Eye Journal Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.14744/bej.2024.05826
Ayse Burcu Dirim, Ibrahim Cagri Turker, Asli Besirli, Mine Ozturk, Elif Ceren Yesilkaya, Oguz Kaan Kutucu, Ekin Ece Oskan
{"title":"Assessment of Anxiety, Depression, Self-Esteem, and Quality-of-Life in Patients Undergoing Surgical Removal of an Eye.","authors":"Ayse Burcu Dirim, Ibrahim Cagri Turker, Asli Besirli, Mine Ozturk, Elif Ceren Yesilkaya, Oguz Kaan Kutucu, Ekin Ece Oskan","doi":"10.14744/bej.2024.05826","DOIUrl":"10.14744/bej.2024.05826","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study was to compare anxiety, depression, self-esteem, and quality of life in patients who underwent surgical removal of an eye with those of controls as well as to test the correlations of these variables in both groups.</p><p><strong>Methods: </strong>Beck anxiety inventory (BAI), Beck depression inventory (BDI), 36-item short-form health survey (SF-36), and Rosenberg self-esteem scale were administered to 29 patients with surgical removal of an eye and 30 control subjects.</p><p><strong>Results: </strong>The patient group had significantly lower scores on physical functioning, role limitations due to physical and emotional problems, pain, and general health perception domains of SF-36, as well as significantly higher BDI (p=0.004) scores as compared to controls. The study groups did not differ significantly with respect to BAI scores and energy/vitality, mental health, and social functioning domain scores of SF-36 (p>0.05).</p><p><strong>Conclusion: </strong>This population of monocular patients had similar mental health-related and Beck's Anxiety Inventory scores equivalent to the control group despite the surgical removal of one eye. However, lower scores for some SF-36 domains and higher depression levels in this patient group suggest that psychiatric rehabilitation should be considered after eye removal to improve the psychological outcomes and quality of life in these patients.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"9 2","pages":"86-94"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Affecting the Results of Ahmed Glaucoma Valve Implantation in Diabetic Neovascular Glaucoma With or Without Previous Pars Plana Vitrectomy. 影响糖尿病新生血管性青光眼患者接受艾哈迈德青光眼瓣膜植入术(无论之前是否进行过玻璃体旁切除术)效果的因素。
Beyoglu Eye Journal Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.14744/bej.2024.64497
Hatice Tekcan, Serhat Imamoglu, Yucel Ozturk
{"title":"Factors Affecting the Results of Ahmed Glaucoma Valve Implantation in Diabetic Neovascular Glaucoma With or Without Previous Pars Plana Vitrectomy.","authors":"Hatice Tekcan, Serhat Imamoglu, Yucel Ozturk","doi":"10.14744/bej.2024.64497","DOIUrl":"10.14744/bej.2024.64497","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to compare the outcomes of Ahmed glaucoma valve implantation (AGVI) in neovascular glaucoma (NVG) due to proliferative diabetic retinopathy (PDR) with or without a pars plana vitrectomy (PPV) history and to analyze the factors affecting surgical failure.</p><p><strong>Methods: </strong>Patients with NVG secondary to PDR undergoing AGVI at a single center were reviewed retrospectively. The surgical failure rates and post-operative complications were compared between eyes with (PPV-AGVI group) and without previous PPV (AGVI group). Failure was defined as loss of light perception or intraocular pressure (IOP) >17 mmHg despite maximum medication, or need of additional intervention for IOP control or for the management of complications. Survival analysis was investigated by Kaplan-Meier test. The possible factors for failure were analyzed with logistic regression analysis.</p><p><strong>Results: </strong>The failure rates were 21.9% during the mean follow-up of 27.56±15.38 months and 14.3% during 23.63±12.38 months, in PPV-AGVI group (n=32) and in AGVI group (n=49), respectively (p=0.37). The frequency of complications and surgical intervention need for management of post-operative complications was similar between groups (p>0.05). There was no significant difference in survival analysis (p=0.13). The history of intravitreal anti-vascular endothelial growth factor (anti-VEGF) injection before AGVI was significantly associated with failure (odds ratio = 26.941, p=0.02).</p><p><strong>Conclusion: </strong>The results of AGVI performed with long scleral tunnel technique were comparable in terms of failure rates, between NVG patients with and without previous diabetic vitrectomy. The only significant factor for failure was intravitreal anti-VEGF pre-treatment. This may be related to the necessity of anti-VEGF therapy in aggressive PDR, and also, anti-VEGF agents may increase fibrosis in the anterior chamber angle.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"9 2","pages":"76-85"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolated Inferior Rectus Muscle Rupture and Surgical Repair: A Case Report. 孤立的下直肌断裂和手术修复:病例报告
Beyoglu Eye Journal Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.14744/bej.2024.91489
Elif Ertan, Seyfi Aydin, Havva Kaldirim
{"title":"Isolated Inferior Rectus Muscle Rupture and Surgical Repair: A Case Report.","authors":"Elif Ertan, Seyfi Aydin, Havva Kaldirim","doi":"10.14744/bej.2024.91489","DOIUrl":"10.14744/bej.2024.91489","url":null,"abstract":"<p><p>We describe the case of a 37-year-old male who experienced an isolated rupture of the inferior rectus muscle in the right eye following a facial impact from a wire. Upon examination, a minor restriction in downward gaze was observed. An orbital computed tomography scan confirmed the integrity of the globe and the absence of an orbital fracture-subsequent surgical exploration involved identifying and suturing together the distal and proximal ends of the affected muscle. Postoperatively, normal eye movements were restored.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"9 2","pages":"106-108"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in Corneal Dynamics and Effective Optical Zone After Transepithelial Photorefractive Keratectomy for Myopia. 经皮层光屈光性角膜切除术治疗近视后角膜动力学和有效光学区的变化。
Beyoglu Eye Journal Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.14744/bej.2024.93075
Gulay Yalcinkaya Cakir, Ihsan Cakir, Burcin Kepez Yildiz, Yusuf Yildirim
{"title":"Changes in Corneal Dynamics and Effective Optical Zone After Transepithelial Photorefractive Keratectomy for Myopia.","authors":"Gulay Yalcinkaya Cakir, Ihsan Cakir, Burcin Kepez Yildiz, Yusuf Yildirim","doi":"10.14744/bej.2024.93075","DOIUrl":"10.14744/bej.2024.93075","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study was to analyze the changes in the effective optical zones (EOZ) using topographic techniques on the tangential curvature difference map at post-operative 1-year following transepithelial photorefractive keratectomy (T-PRK) and to identify parameters linked to the EOZ alterations.</p><p><strong>Methods: </strong>The study comprised 55 eyes of 55 myopic patients who underwent T-PRK. EOZs were measured using the tangential curvature difference map of the Scheimpflug tomography system. Correlations between the EOZ alterations and relevant parameters were assessed.</p><p><strong>Results: </strong>The EOZ was significantly lower than the programmed optical zone (p<0.001). The decrease in the EOZ was significantly relevant to the decrease in mean keratometry (p=0.01, B/95% confidence interval [CI]: 0.139/0.033 and 0.244, standardized Beta: 0.346) and the increase in maximum keratometry (p=0.003, B/95% CI: 0.072/0.026 and 0.118, standardized Beta: 0.406).</p><p><strong>Conclusion: </strong>The EOZ decreased in the 1<sup>st</sup> year after T-PRK in eyes with myopia. The decrease in the EOZ was correlated positively with the decrease in mean and maximum keratometry. T-PRK may be an effective and safe surgery for the correction of mild-to-moderate myopia.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"9 2","pages":"69-75"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156476/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tectonic and Therapeutic Urgent Penetrating Keratoplasty Outcomes. 构造性和治疗性急诊穿透性角膜移植术的结果。
Beyoglu Eye Journal Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.14744/bej.2024.69772
Yusuf Cem Yilmaz, Serife Ciloglu Hayat, Gizem Sayar Bilgin, Emre Altinkurt
{"title":"Tectonic and Therapeutic Urgent Penetrating Keratoplasty Outcomes.","authors":"Yusuf Cem Yilmaz, Serife Ciloglu Hayat, Gizem Sayar Bilgin, Emre Altinkurt","doi":"10.14744/bej.2024.69772","DOIUrl":"10.14744/bej.2024.69772","url":null,"abstract":"<p><strong>Objectives: </strong>It was aimed to to provide a comprehensive assessment of therapeutic and tectonic emergency keratoplasty procedures, along with a discussion on their indications, prognostic factors for functional success, and postoperative outcomes.</p><p><strong>Methods: </strong>Patients who underwent therapeutic or tectonic Penetrating Keratoplasty (PKP) procedures between 2010 to 2021 in our hospital were retrospectively reviewed. Patient files were evaluated in terms of demographic characteristics, medical and ocular history, visual acuity, initial ocular findings, presence of glaucoma, causative microorganisms, details of surgical procedures, complications, graft transparency and globe integrity. Visual acuity was measured as light perception, hand motion, counting finger, Snellen chart and subsequently converted to Logarithm of the Minimum Angle of Resolution (logMAR) for statistical analysis.</p><p><strong>Results: </strong>The study included a total of 43 patients, with 16 (37.2%) being female. The average age of the participants was 59.72±18.1 years. The corrected distance visual acuity improved from 2.3±0.66 logMAR preoperatively to 1.72±1.02 logMAR postoperatively (p=0.001). After PKP, anatomical success was achieved in all eyes and functional success was achieved in 23 (51.1%) eyes. It was observed that only preoperative glaucoma had a significant impact on graft survival rate (p=0.002, Figure 2), as well as functional success (p=0.022).</p><p><strong>Conclusion: </strong>Urgent keratoplasty is a viable treatment option for cases involving an actively uncontrolled infection or corneal disease with perforation. In cases of graft rejection, bacteria, fungi, and viral pathogens were detected as causative agents, whereas only bacteria were detected as the causative agents in cases of pre and post-operative endophthalmitis. Early diagnosis and treatment play crucial roles in achieving anatomical and functional success.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"9 2","pages":"61-68"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can Serum Biomarker Values from Second-Trimester Aneuploidy Screening Predict the development of Retinopathy of Prematurity in Premature Infants? 二胎非整倍体筛查得出的血清生物标志物值能否预测早产儿早产视网膜病变的发生?
Beyoglu Eye Journal Pub Date : 2024-06-01 eCollection Date: 2024-01-01 DOI: 10.14744/bej.2024.81598
Senol Sabanci, Mehmet Fatih Kucuk, Hasan Basri Savas, Elcin Suren, Muhammet Kazim Erol, And Yavuz, Haydar Sipahioglu
{"title":"Can Serum Biomarker Values from Second-Trimester Aneuploidy Screening Predict the development of Retinopathy of Prematurity in Premature Infants?","authors":"Senol Sabanci, Mehmet Fatih Kucuk, Hasan Basri Savas, Elcin Suren, Muhammet Kazim Erol, And Yavuz, Haydar Sipahioglu","doi":"10.14744/bej.2024.81598","DOIUrl":"10.14744/bej.2024.81598","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate serum biomarker values measured during second-trimester aneuploidy screening in terms of their predictive ability for the development of retinopathy of prematurity (ROP) in premature infants.</p><p><strong>Methods: </strong>This retrospective cohort study evaluated the data of 1985 idiopathic premature infants who underwent ROP screening from 2016 to 2022. The infants were divided into two groups according to the presence of ROP, and those with ROP were further evaluated in two subgroups based on the presence of proliferation. Comparisons were made concerning the serum multiple of the median values of unconjugated estriol (uE3), human chorionic gonadotropin (hCG), and alpha-fetoprotein (AFP) among aneuploidy screening biomarkers.</p><p><strong>Results: </strong>While 1628 premature infants were in the non-ROP group, 357 were in the ROP group. Of the infants with ROP, 72 were in the proliferative ROP group and 285 in the non-proliferative ROP group. There was no significant difference in the multiple of the median values of the evaluated serum biomarkers (uE3, hCG, and AFP) between the ROP and non-ROP groups or between the proliferative ROP, non-proliferative ROP, and non-ROP groups.</p><p><strong>Conclusion: </strong>The multiple of the median values of second-trimester aneuploidy screening serum biomarkers were not able to predict the development of ROP in premature infants. This result may have been caused by the fact that the blood tests were taken only once and in the same weeks.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"9 2","pages":"95-100"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding the Etiopathogenesis of Non-Arteritic Anterior Ischemic Optic Neuropathy with Laboratory Findings. 通过实验室检查结果了解非动脉炎性前部缺血性视神经病变的发病机制。
Beyoglu Eye Journal Pub Date : 2024-03-01 eCollection Date: 2024-01-01 DOI: 10.14744/bej.2023.09815
Neslisah Kutlu Uzakgider, Seda Karaca Adiyeke, Hasan Aytogan
{"title":"Understanding the Etiopathogenesis of Non-Arteritic Anterior Ischemic Optic Neuropathy with Laboratory Findings.","authors":"Neslisah Kutlu Uzakgider, Seda Karaca Adiyeke, Hasan Aytogan","doi":"10.14744/bej.2023.09815","DOIUrl":"https://doi.org/10.14744/bej.2023.09815","url":null,"abstract":"<p><strong>Objectives: </strong>The role of inflammation and hemostasis in non-arteritic anterior ischemic optic neuropathy (NAION) was investigated by examining related blood tests. The predictive values of these laboratory indicators and their effects on prognosis were reviewed.</p><p><strong>Methods: </strong>In this study, 48 patients diagnosed with NAION and 50 healthy volunteers were included. All subjects underwent full ophthalmological examination. All patients were treated with oral corticosteroids (methylprednisolone 1 mg/kg/day) for 15 days after that corticosteroid medication was reduced and stopped. Each patient was monitored at least for 12 months. The mean platelet volume (MPV), platelet distribution width (PDW), neutrophil/lymphocyte ratio (NLR), and red cell distribution width (RDW) values were recorded. These findings were compared with control group.</p><p><strong>Results: </strong>The mean MPV, RDW, and NLR values were significantly higher in NAION group (respectively, p<0.001, p=0.006, and p<0.001). There was no statistically significant difference between group 1 and group 2 in PDW values, but the mean PDW value was higher in the patient group compared to the control group (p=0.435). Based on the receiver operating characteristic (ROC) curve, the NLR had the strongest predictive value. This was followed by MPV, RDW, and PDW with lower diagnostic predictive values.</p><p><strong>Conclusion: </strong>MPV, NLR, and RDW were found to be elevated and have diagnostic predictive values in NAION patients. Easily accessible and simple laboratory methods could help us show systemic inflammation and ischemic events in NAION patients. As a result, inflammatory reactions besides ischemic changes may play a role in the etiopathogenesis of NAION. These biomarkers can be evaluated to ensure that patients with risk factors for the development of NAION.</p>","PeriodicalId":8740,"journal":{"name":"Beyoglu Eye Journal","volume":"9 1","pages":"8-13"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10944851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140179333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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