Behavioral and neural biology最新文献_第7页

The effects of morphine on memory consolidation in mice involve both D1 and D2 dopamine receptors 吗啡对小鼠记忆巩固的影响涉及D1和D2多巴胺受体

Behavioral and neural biology Pub Date : 1994-03-01 DOI: 10.1016/S0163-1047(05)80069-X

Claudio Castellano , Vincenzo Cestari , Simona Cabib , Stefano Puglisi-Allegra

{"title":"The effects of morphine on memory consolidation in mice involve both D1 and D2 dopamine receptors","authors":"Claudio Castellano , Vincenzo Cestari , Simona Cabib , Stefano Puglisi-Allegra","doi":"10.1016/S0163-1047(05)80069-X","DOIUrl":"10.1016/S0163-1047(05)80069-X","url":null,"abstract":"<div><p>Post-training administration of morphine (0.25, 0.5, or 1 mg/kg) dose-dependently impairs retention of an inhibitory avoidance response in mice. The effects on retention performance induced by the drug appear to be due to an effect on memory consolidation. In fact, they were observed when drugs were given at short, but not long, periods of time after training, i.e., when the memory trace was susceptible to modulation. Moreover, these effects are not to be ascribed to an aversive or a rewarding or nonspecific action of the drugs on retention performance, because the latencies during the retention test of those mice that had not received a footshock during the training were not affected by post-training drug administration. Pretreatment with either selective D1 or D2 dopamine (DA) receptor antagonists SCH 23390 and (-)-sulpiride administered at per se noneffective doses (0.025 and 6 mg/kg, respectively) potentiated the effects of morphine, while either selective D1 or D2 receptor agonists SKF 38393 and LY 171555 at per se noneffective doses (5 and 0.25 mg/kg, respectively) antagonized the effects of the opiate on memory consolidation. No significant differences were evident between the effects of D1 and D2 receptor active compounds, thus suggesting that D1 and D2 receptor types are similarly involved in the effects of morphine on memory consolidation, in agreement with previously reported results. These results are discussed in terms of a possible inverse relationship of endogenous opioid and DA systems in the brain that are involved in memory processes.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"61 2","pages":"Pages 156-161"},"PeriodicalIF":0.0,"publicationDate":"1994-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0163-1047(05)80069-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18908021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 51

Differential recovery of inhibitory avoidance learning by striatal, cortical, and mesencephalic fetal grafts 纹状体、皮质和中脑胎儿移植对抑制性回避学习的差异恢复

Behavioral and neural biology Pub Date : 1994-03-01 DOI: 10.1016/S0163-1047(05)80076-7

A.L. Piña, C.E. Ormsby, F. Bermúdez-Rattoni

{"title":"Differential recovery of inhibitory avoidance learning by striatal, cortical, and mesencephalic fetal grafts","authors":"A.L. Piña, C.E. Ormsby, F. Bermúdez-Rattoni","doi":"10.1016/S0163-1047(05)80076-7","DOIUrl":"10.1016/S0163-1047(05)80076-7","url":null,"abstract":"<div><p>Four groups of male Wistar rats showing disrupted inhibitory avoidance conditioning due to striatal lesions were studied. Three groups received striatal, cortical, or ventral mesencephalic brain grafts and the fourth group remained as a lesioned control. Sixty days postgraft the animals were retrained in an inhibitory avoidance task. The striatal-grafted animals were the only group that significantly improved in the ability to acquire the inhibitory avoidance task. Acetylcholinesterase histochemistry revealed positive patches of cells in the striatal grafts. Cortical grafts showed less reactivity, without patches. Immunocytochemical analyses for tyrosine hydroxylase revealed positive cell reactivity in the mesencephalic grafts and few positive fibers were detected in the border between the striatal grafts and the host tissue. These results demonstrate that striatal but not cortical or mesencephalic brain grafts can promote the restoration of the ability to acquire an inhibitory avoidance task and suggest that the acetylcholine tissue content is involved in the behavioral recovery.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"61 2","pages":"Pages 196-201"},"PeriodicalIF":0.0,"publicationDate":"1994-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0163-1047(05)80076-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19194053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Multivariate analysis of behavioral aging highlights some unexpected features of complex systems organization 行为老化的多变量分析突出了复杂系统组织的一些意想不到的特征

Behavioral and neural biology Pub Date : 1994-03-01 DOI: 10.1016/S0163-1047(05)80064-0

Alessandro Giuliani , Orlando Ghirardi , Antonio Caprioli , Stefano di Serio , Maria Teresa Ramacci , Luciano Angelucci

引用次数: 19

Pavlovian inhibitory conditioning and tolerance-reversal to scopolamine-induced adipsia in rats 巴甫洛夫抑制条件反射和对东莨菪碱诱导的肥胖大鼠的耐受逆转

Behavioral and neural biology Pub Date : 1994-03-01 DOI: 10.1016/S0163-1047(05)80072-X

Javier Vila C., Florencio Miranda H.

引用次数: 3

Learning under partial reinforcement in the toad (Bufo arenarum): Effects of lesions in the medial pallium 蟾蜍(Bufo arenarum)部分强化下的学习:内侧白质损伤的影响

Behavioral and neural biology Pub Date : 1994-01-01 DOI: 10.1016/S0163-1047(05)80042-1

Rubén N. Muzio, Enrique T. Segura, Mauricio R. Papini

引用次数: 30

Modulation of respiratory pump rate by reproductive behaviors in freely behaving pairs of aplysia fasciata 自由行为的筋膜阔板对繁殖行为对呼吸泵频率的调节

Behavioral and neural biology Pub Date : 1994-01-01 DOI: 10.1016/S0163-1047(05)80048-2

Miriam Levy, Sylvia Markovich, Abraham J. Susswein

引用次数: 8

Serotonin depletion inhibits feeding in carnivorous leeches (Haemopis) 5 -羟色胺缺失抑制食肉水蛭(血蛭)的摄食

Behavioral and neural biology Pub Date : 1994-01-01 DOI: 10.1016/S0163-1047(05)80043-3

Valerie Goldburt, Behir A. Sabban, Anna L. Kleinhaus

{"title":"Serotonin depletion inhibits feeding in carnivorous leeches (Haemopis)","authors":"Valerie Goldburt, Behir A. Sabban, Anna L. Kleinhaus","doi":"10.1016/S0163-1047(05)80043-3","DOIUrl":"10.1016/S0163-1047(05)80043-3","url":null,"abstract":"<div><p>The effect of reserpine on the serotonin content of the central nervous system and the feeding behavior of the carnivorous leech <em>Haemopis marmorata</em> was investigated. Leeches were hand-fed to satiation by presentation of pieces of chicken liver held in forceps for three meals at 4-day intervals prior to and 1 week following three consecutive injections of 100 μg reserpine in the crop. A group matched by weight and preinjection food intake was injected with the vehicle in a blind experimental design. Histochemical and chemical determinations showed that reserpine effectively depleted the serotonin content of the animal's central nervous system. Furthermore, the food intake of reserpine-treated animals was significantly less than that of the sham-injected group. However, the depleted animals continued to ingest approximately 40% of the amount consumed during the preinjection period. These results show that reserpine successfully depleted the serotonin in the carnivorous leech <em>H. marmorata</em> and decreased the food intake of this leech species. They suggest that feeding behavior in <em>Haemopis</em> is partially but not exclusively dependent on serotonin and that, in contrast to the sanguivorous leeches, additional factors may be necessary for its regulation.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"61 1","pages":"Pages 47-53"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0163-1047(05)80043-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19121224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

An investigation of habituation in the jellyfish Aurelia aurita 水母习性的研究

Behavioral and neural biology Pub Date : 1994-01-01 DOI: 10.1016/S0163-1047(05)80044-5

Mary C. Johnson, Karl L. Wuensch

引用次数: 20

Influence of auditory experience on the development of brain stem auditory-evoked potentials in mallard duck embryos and hatchlings 听觉体验对绿头鸭胚胎及幼雏脑干听觉诱发电位发育的影响

Behavioral and neural biology Pub Date : 1994-01-01 DOI: 10.1016/S0163-1047(05)80040-8

Lubov P. Dmitrieva, Gilbert Gottlieb

{"title":"Influence of auditory experience on the development of brain stem auditory-evoked potentials in mallard duck embryos and hatchlings","authors":"Lubov P. Dmitrieva, Gilbert Gottlieb","doi":"10.1016/S0163-1047(05)80040-8","DOIUrl":"10.1016/S0163-1047(05)80040-8","url":null,"abstract":"<div><p>The development of brain stem auditory-evoked potentials (BAEP) was studied in devocalized ducklings reared in auditory isolation and in vocal ducklings exposed to enhanced species-specific auditory stimulation with embryonic contact-contentment calls (CTs). Thresholds and latency of BAEP wave P<sub>1</sub> in the mute ducklings indicated that even short-term auditory deprivation affected the development of auditory sensitivity, substantially reducting the rate of decline in BAEP thresholds and latencies of P<sub>1</sub>, especially in the low-frequency (500 and 750 Hz) and high-frequency (above 2.0 kHz) ranges. The ducklings exposed to enhanced stimulation, on the other hand, showed an accelerated decline in BAEP thresholds and latencies of P<sub>1</sub> across all test frequencies, with the most marked influence on low (below 1.5 kHz) and high (above 2.5 kHz) frequencies. The influence of species-specific auditory experience had its most potent effect during the embryonic critical period for postnatal auditory perceptual (behavioral) development, at which time the embryo produces and hears a special low-frequency (1.5–2.5 kHz) version of its own contact-contentment vocalization.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"61 1","pages":"Pages 19-28"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0163-1047(05)80040-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19123107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Modification of 8-OH-DPAT effects on learning by manipulation of the assay conditions 8-OH-DPAT对学习的影响

Behavioral and neural biology Pub Date : 1994-01-01 DOI: 10.1016/S0163-1047(05)80041-X

Alfredo Meneses , Enrique Hong

{"title":"Modification of 8-OH-DPAT effects on learning by manipulation of the assay conditions","authors":"Alfredo Meneses , Enrique Hong","doi":"10.1016/S0163-1047(05)80041-X","DOIUrl":"10.1016/S0163-1047(05)80041-X","url":null,"abstract":"<div><p>A role for the 5-HT<sub>1A</sub> receptor in learning and memory has been suggested by diverse evidence. The present paper deals with the acute effect of 8-OH-DPAT (a 5-HT<sub>1A</sub> agonist) administered to rats before or after training in an autoshaped lever-press response (a model of associative learning). The results show that 8-OH-DPAT improved consolidation of the conditioned response (CR) when injected post-training, but impaired it with pretraining administration. Both effects were time-dependent. When the compound was administered pre- or post-training to free-feeding or prefeeding animals, they did not learn the CR. When it was administered to retrained food-deprived animals, the compound was also inactive. However, with retrained animals on a free-feeding schedule, pre- or post-training administration of 8-OH-DPAT enhanced retrieval in a dose-dependent fashion. Pretraining administration of 8-OH-DPAT impaired food intake and exploration, and therefore learning. The present results strongly suggest a role of 5-HT<sub>1A</sub> receptors in the consolidation and retrieval of learning. Such improvement is independent of food intake.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"61 1","pages":"Pages 29-35"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0163-1047(05)80041-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19123108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 33