Behavioral and neural biology最新文献

{"title":"Author index for volume 60","authors":"","doi":"10.1016/0163-1047(93)90618-R","DOIUrl":"https://doi.org/10.1016/0163-1047(93)90618-R","url":null,"abstract":"","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 3","pages":"Page 287"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90618-R","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137190718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of catecholaminergic depletion of the amygdala and insular cortex on the potentiation of odor by taste aversions","authors":"Juan Fernandez-Ruiz ,&nbsp;Maria Isabel Miranda ,&nbsp;Federico Bermúdez-Rattoni ,&nbsp;René Drucker-Colín","doi":"10.1016/0163-1047(93)90314-8","DOIUrl":"10.1016/0163-1047(93)90314-8","url":null,"abstract":"<div><p>This experiment examined the effects of catecholamine depletion of the amygdala or insular cortex on the acquisition of olfactory and gustatory learning tasks. Bilateral lesions with 6-hydroxydopamine (4 <em>μ</em>g/0.5 <em>μ</em>l) were done in either amygdala or insular cortex of Wistar male rats, with two groups receiving sham lesions. All four groups of animals were trained and tested in the potentiation of odor by taste aversion paradigm. The results showed that the amygdala-lesioned group acquired the taste, but not the odor aversion, while the insular cortexlesioned group acquired odor, but not taste aversion. Both sham groups showed strong taste and odor aversions. Catecholamine levels in both lesioned groups were significantly lower than those in the sham groups. These results suggest that catecholamines are necessary in the insular cortex for the acquisition of taste and in the amygdala for the acquisition of odor aversion in the potentiation of odor by taste aversion paradigm.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 3","pages":"Pages 189-191"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90314-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19285671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual experience and preferences for odors of estrous females in staggerer mutant male mice","authors":"Christophe Féron,&nbsp;Claude Baudoin","doi":"10.1016/0163-1047(93)90561-U","DOIUrl":"10.1016/0163-1047(93)90561-U","url":null,"abstract":"<div><p>Staggerer mutant male mice generally do not mate and olfactory disabilities may be involved. Choice tests were used to determine the preference of C57BL/6 male mice with the staggerer mutation for urine and vaginal secretions from receptive and unreceptive females. The staggerer mutation does not prevent the olfactory discrimination between vaginal secretions of estrous and anestrous females. Male preferences for odors of receptive females are related to the presence of sexual experience.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 3","pages":"Pages 280-281"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90561-U","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19284842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cumulative subject index for volumes 59–60","authors":"","doi":"10.1016/0163-1047(93)90637-W","DOIUrl":"https://doi.org/10.1016/0163-1047(93)90637-W","url":null,"abstract":"","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 3","pages":"Pages 288-295"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90637-W","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137190717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serotonergic influence on olfactory learning in the neonate rat","authors":"John H. McLean ,&nbsp;Andrea Darby-King ,&nbsp;Regina M. Sullivan ,&nbsp;Shelley R. King","doi":"10.1016/0163-1047(93)90257-I","DOIUrl":"10.1016/0163-1047(93)90257-I","url":null,"abstract":"<div><p>The role of the serotonergic innervation of the olfactory bulb was examined in neonate rat pups (Sprague—Dawley) by utilizing an olfactory learning paradigm (<span>Sullivan, McGaugh, &amp; Leon, 1991</span>;<span>Sullivan, Wilson, &amp; Leon, 1989</span>). One hundred fifty nanoliters of the neurotoxin 5,7-dihydroxytryptamine (5,7-dHT, 10 <em>μ</em>g/<em>μ</em>l) was injected into each anterior olfactory nucleus of Postnatal Day 2 (PND 2) pups in order to selectively deplete the serotonergic (5-HT) innervation of the olfactory bulb. On PND 8, control, sham-operated, or 5-HT-depleted pups were presented with stroke (unconditioned stimulus) paired with peppermint odor (conditioned stimulus) or were presented with peppermint alone. Other pups remained naive, i.e., they were not presented with either stroke or odor. The following day, the pups were placed on a mesh screen above two boxes containing either fresh bedding or bedding with peppermint odor for five 1-min trials. Control and sham-operated pups that were previously trained by the odor/stroke paradigm spent significantly more time over the peppermint odor than similarly trained 5-HT-depleted pups, pups trained using the odor only paradigm, or naive pups. Immunocytochemistry verified that the 5,7-dHT injections specifically depleted the 5-HT innervation of the olfactory bulb and left the 5-HT innervation of more caudal levels of the neuraxis (e.g., piriform cortex) intact. The locomotor behavior of the pups was not affected by the 5-HT depletions. This study is the initial investigation to suggest that 5-HT innervation to the olfactory bulb is important in the acquisition or expression of olfactorybased learned behavior in the neonate rat.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 2","pages":"Pages 152-162"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90257-I","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18906158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acknowledgment","authors":"","doi":"10.1016/0163-1047(93)90313-7","DOIUrl":"https://doi.org/10.1016/0163-1047(93)90313-7","url":null,"abstract":"","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 2","pages":"Page 187"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90313-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92034169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interaction of β-endorphin and GABAergic drugs in the regulation of memory storage","authors":"Claudio Castellano,&nbsp;Ines B. Introini-Collison ,&nbsp;James L. McGaugh","doi":"10.1016/0163-1047(93)90215-4","DOIUrl":"10.1016/0163-1047(93)90215-4","url":null,"abstract":"<div><p>These experiments examined the interaction of <em>β</em>-endorphin and GABAergic drugs, administered post-training, in influencing retention of an inhibitory avoidance response. Male CD1 mice were trained in an inhibitory avoidance task, given immediate post-training ip injections and tested 24 h later for retention. <em>β</em>-Endorphin (0.5, 1.0, or 2.0 <em>μ</em>g/kg) and muscimol (0.5, 1.0, or 2.0 mg/kg) produced dose-dependent impairment of retention; picrotoxin (0.25, 0.5, or 1.0 mg/kg) and bicuculline (0.1, 0.25, or 0.5 mg/kg) produced dose-dependent enhancement of retention. A low subeffective dose of muscimol (0.5 mg/kg) potentiated the retention-impairing effect of <em>β</em>-endorphin (1.0 <em>μ</em>g/kg). In addition, concurrent administration of low, subeffective doses of bicuculline (0.1 mg/kg) or picrotoxin (0.25 mg/kg) attenuated the retention-impairing effects of <em>β</em>-endorphin (1.0 <em>μ</em>g/kg). The findings are consistent with previous evidence indicating that <em>β</em>-endorphin influences memory through an interaction with GABAergic mechanisms.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 2","pages":"Pages 123-128"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90215-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19109711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time gradient for post-test vulnerability to scopolamine-induced amnesia following the initial acquisition session of a spatial reference memory task in mice","authors":"Abdoulaye Toumane ,&nbsp;Thomas P. Durkin","doi":"10.1016/0163-1047(93)90243-B","DOIUrl":"10.1016/0163-1047(93)90243-B","url":null,"abstract":"<div><p>The time course for vulnerability to the amnestic effects of the cholinergic antagonist, scopolamine, during the postacquisition period has been investigated. We have examined the effects of post-test injections of scopolamine (1 mg/kg ip) given at different times from 30 s for up to 6 h following the end of the first acquisition session of a concurrent spatial discrimination (reference memory) protocol in an 8-arm radial maze on subsequent long-term (24 h) retention performance in C57BL/6 mice. Results show that the immediate (30 s) post-test injection of scopolamine—HCl on Day 1 produces marked perturbation (amnesia) of long-term retention as attested to by significant deficits in various indices of spatial discrimination performance gain on Day 2 as compared to control subjects injected either with scopolamine—MBr or saline. The severity of this scopolamine-induced amnesia declines only slightly as a function of the treatment period 30 s—3 h post-test. However, no evidence for amnesia is observed if scopolamine—HCl injections are delayed for 6 h postsession. This important latter observation attests to the absence of any significant proactive effects of scopolamine on the ability of mice to perform the retention test via possible long-term effects on attention, motivation, or locomotor performance. These results thus constitute evidence for the existence of a limited (30 s–3 h) time gradient for vulnerability of the early memory trace to disruption by scopolamine. The present results are dis cussed in relation to our previous direct neurochemical observations describing the differential time courses of intervention of the ascending septohippocampal and nBM—cortical cholinergic pathways in the postlearning period. In particular, the presently observed time window concerning post-test vulnerability to scopolamine-induced amnesia corresponds more closely to the time course of the acute activation of the nBM—cortical cholinergic pathway, induced by testing with the same spatial memory protocol as used in the present study in mice.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 2","pages":"Pages 139-151"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90243-B","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19109609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"7-Chlorokynurenate, an antagonist of the glycine binding site on the NMDA receptor, inhibits memory formation in day-old chicks (Gallus domesticus)","authors":"Robert J. Steele,&nbsp;Michael G. Stewart","doi":"10.1016/0163-1047(93)90145-8","DOIUrl":"10.1016/0163-1047(93)90145-8","url":null,"abstract":"<div><p>Unilateral intracranial injection into the left intermediate and medial hyperstriatum ventrale of 100 <em>μ</em>mol · liter⁻¹ 7-chlorokynurenate, a highly selective antagonist of the glycine site on the <em>N</em>-methyl-<span>d</span>-aspartate receptor, prevents acquisition of memory for one-trial passive avoidance training in day-old chicks, in which the aversive stimulus is an unpleasant tasting substance, methyl anthranilate. Injections were given 30 min pretraining and the chicks were tested 30 min or 1 or 3 h post-training. Unilateral injections into the left intermediate and medial hyperstriatum ventrale were found to significantly block memory acquisition when birds were tested at all three time points, but unilateral injections in the right intermediate and medial hyperstriatum ventrale had no significant effect. Bilateral injections did not significantly increase the memory block. Injections of 7-chlorokynurenate given 5 min post-training failed to produce amnesia for the avoidance task when chicks were tested either 30 min or 1 h after training.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 2","pages":"Pages 89-92"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90145-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19109612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disruptive influence of norepinephrine depletion on sensory preconditioning, but not first-order conditioning, in preweanling rats","authors":"Wei-Jung A. Chen,&nbsp;Linda P. Spear,&nbsp;Norman E. Spear","doi":"10.1016/0163-1047(93)90187-M","DOIUrl":"10.1016/0163-1047(93)90187-M","url":null,"abstract":"<div><p>Learning and memory processes are known to be influenced by the action of norepinephrine (NE). The present study evaluated the influence of neonatal administration of the NE neurotoxin DSP4 on sensory preconditioning (SPC) in 16- and 28-day-old rats. Rats were subcutaneously administered 50 mg/kg DSP4 or saline within 24 h after birth and tested at 16 or 28 days in two experiments. The results from Experiment 1 indicated that nondepleted 16-day-old rats exhibited strong SPC, whereas this conditioning was disrupted by neonatal administration of DSP4. No SPC was seen in either neonatal treatment group at 28 days of age, confirming previous reports of an ontogenetic decline in SPC. In Experiment 2, no effects of DSP4 were observed on first-order conditioning at either age. The brains of representative subjects were separated into forebrain, cerebellum, and brain stem samples and were analyzed to determine the extent of NE depletion. This analysis showed that DSP4 produced a marked reduction in NE concentration in the forebrain, but not in the cerebellum or brain stem. The results of this study suggest a role for forebrain NE in SPC in preweanling rats. This modulatory noradrenergic influence appears to be exerted on the formation of associations between two relatively neutral stimuli during the preexposure phase, given the absence of an effect of DSP4 on primary conditioning.</p></div>","PeriodicalId":8732,"journal":{"name":"Behavioral and neural biology","volume":"60 2","pages":"Pages 110-117"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0163-1047(93)90187-M","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18517195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}