Medical devices & sensors最新文献

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Clinical study of a chest-based cuffless blood pressure monitoring system 胸部无袖带血压监测系统的临床研究
Medical devices & sensors Pub Date : 2020-05-13 DOI: 10.1002/mds3.10091
Fatemeh Heydari, Malikeh P. Ebrahim, Jean-Michel Redoute, Keith Joe, Katie Walker, Alberto Avolio, Mehmet R. Yuce
{"title":"Clinical study of a chest-based cuffless blood pressure monitoring system","authors":"Fatemeh Heydari,&nbsp;Malikeh P. Ebrahim,&nbsp;Jean-Michel Redoute,&nbsp;Keith Joe,&nbsp;Katie Walker,&nbsp;Alberto Avolio,&nbsp;Mehmet R. Yuce","doi":"10.1002/mds3.10091","DOIUrl":"10.1002/mds3.10091","url":null,"abstract":"<p>This work presents a clinical study of a chest-based blood pressure (BP) monitoring technique. This research was designed to examine pulse transit time (PTT) and to measure beat-to-beat and cuff-based systolic BP (SBP) and diastolic BP (DBP). The PTT values were extracted as the time difference between the end of the pre-ejection period (PEP) measured using an on-body continuous-wave radar (CWR) sensor and the pulse arrival time (PAT) in central arteries extracted from the shoulders' bio-impedance (BImp) signal. The system was investigated under three experimental conditions: (a) resting at various postures; (b) rising exercise stress, followed by resting; and (c) spraying inconstant doses of glyceryl trinitrate (GTN) medicine and recovery. Data were collected from 43 volunteers who participated in posture recordings, 26 undertook exercises and 17 experienced GTN spray. The BImp-based PTT was compared with PPG-based one (peripheral) in terms of BP estimation. Various mathematical methods of calculating BPs from PTTs were investigated to gain the most accurate outcomes. We demonstrate the accuracy of each model in this work. Our study found that cuffless BP determined from PTT derived from central arteries shows more than 3% accuracy compared to that determined from peripheral arteries.</p>","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mds3.10091","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42717448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
In situ electrical stimulation for enhanced bone growth: A mini-review 原位电刺激促进骨生长:一个小回顾
Medical devices & sensors Pub Date : 2020-05-12 DOI: 10.1002/mds3.10090
Chandra Khatua, Dipten Bhattacharya, Vamsi Krishna Balla
{"title":"In situ electrical stimulation for enhanced bone growth: A mini-review","authors":"Chandra Khatua,&nbsp;Dipten Bhattacharya,&nbsp;Vamsi Krishna Balla","doi":"10.1002/mds3.10090","DOIUrl":"10.1002/mds3.10090","url":null,"abstract":"<p>The role of electrical stimuli in directing cellular activities during natural tissue healing and regeneration process has been well recognized. This observation has prompted the development and use of exogenous electrical stimulations in the treatment of delayed unions and non-unions of bone fracture in different parts of the human skeletal system. Considerable amount of clinical evidences has also been generated on the benefits of exogenous bone growth stimulators. However, the clinical efficacy and safety of these exogenous electrical stimulating methods are being argued to be inconsistent and inconclusive, due to lack of sufficient number of well-controlled, randomized clinical studies. As a result, there has been significant interest in the development of smart biomaterials, which can generate in situ electrical stimuli, for accelerated bone repair, healing and regeneration. These smart biomaterials are essentially either composite biomaterials containing electrically active materials or biomaterials that can be polarized. The primary objective of this mini review was to provide an overview of different exogenous electrical stimulation methods and biocomposites for in situ stimulation, which can be used for bone growth and healing. The first part is focused on exogenous stimulation methods, and the second part discusses the use of biocomposites containing electrically active materials such as piezoelectric materials and multiferroic materials for accelerated repair and regeneration of bone.</p>","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mds3.10090","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43862165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Rationally designed chimeric solid‐binding peptides for tailoring solid interfaces 合理设计的嵌合固体结合肽用于剪裁固体界面
Medical devices & sensors Pub Date : 2020-05-09 DOI: 10.1002/mds3.10065
Deniz T. Yucesoy, Dimitry Khatayevich, C. Tamerler, M. Sarikaya
{"title":"Rationally designed chimeric solid‐binding peptides for tailoring solid interfaces","authors":"Deniz T. Yucesoy, Dimitry Khatayevich, C. Tamerler, M. Sarikaya","doi":"10.1002/mds3.10065","DOIUrl":"https://doi.org/10.1002/mds3.10065","url":null,"abstract":"Joining biology with materials science requires the ability to design, engineer and control biology/solid-state materials interfaces at the molecular level. The specific molecular interactions that take place among biomolecules, known as molecular recognition, enable all aspects of molecular processes in living systems prerequisite to the biological functions. Having the ability to establish specific biological interactions between the solid materials and biological constituents is essential for precise design of biologically viable soft interfaces that are molecularly tailored at solid surfaces. Solid-binding peptides offer excellent opportunities in surface biofunctionalization over the traditionally utilized chemical approaches","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mds3.10065","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48582955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
A perspective on sepsis pathogenesis, biomarkers and diagnosis: A concise survey 脓毒症的发病机制、生物标志物和诊断:一个简明的调查
Medical devices & sensors Pub Date : 2020-05-04 DOI: 10.1002/mds3.10089
Souvik Kundu, Shawana Tabassum, Ratnesh Kumar
{"title":"A perspective on sepsis pathogenesis, biomarkers and diagnosis: A concise survey","authors":"Souvik Kundu,&nbsp;Shawana Tabassum,&nbsp;Ratnesh Kumar","doi":"10.1002/mds3.10089","DOIUrl":"10.1002/mds3.10089","url":null,"abstract":"<p>Sepsis is a potentially fatal physiological state caused by an imbalance in the body's immune response to an infection and is one of the most common causes for deaths in the non-coronary intensive care unit worldwide. In this article, the state of art on sepsis is presented in a manner that facilitates easy comprehension also for the non-medical researchers by introducing sepsis, its causes, extent and comparison of diagnostic techniques (conventional labeled as well as label-free detection). The article also provides a comprehensive discussion on sepsis biomarkers, to help researchers from multi-disciplinary domain in developing devices and ideas to complement the existing sepsis diagnosis systems for quick and premature detection of the physiological condition and reduce mortality by means of early treatments.</p>","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mds3.10089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41331039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Examining the design, manufacturing and analytics of smart wearables 检查智能可穿戴设备的设计、制造和分析
Medical devices & sensors Pub Date : 2020-04-28 DOI: 10.1002/mds3.10087
Ximena López, K. Afrin, Bimal P. Nepal
{"title":"Examining the design, manufacturing and analytics of smart wearables","authors":"Ximena López, K. Afrin, Bimal P. Nepal","doi":"10.1002/mds3.10087","DOIUrl":"https://doi.org/10.1002/mds3.10087","url":null,"abstract":"Recent advancements in sensors, device manufacturing and big data technologies have enabled the design and manufacturing of smart wearables for a wide array of applications in health care. These devices can be used to remotely monitor and diagnose various diseases and aid in the rehabilitation of patients. Smart wearables are an unobtrusive and affordable alternative to costly and time-consuming healthcare efforts such as hospitalization and late diagnosis. Developments in micro- and nanotechnologies have led to the miniaturization of sensors, hybrid 3D printing of flexible plastics, embedded electronics and intelligent fabrics, as well as wireless communication mediums that permit the processing, storage and communication of data between patients and healthcare facilities.","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mds3.10087","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42393890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Bio-electrochemical response to sense implant degradation 传感植入物降解的生物电化学响应
Medical devices & sensors Pub Date : 2020-04-28 DOI: 10.1002/mds3.10088
Jibril Shittu, Maryam Sadeghilaridjani, Mayur Pole, Aditya Ayyagari, Sundeep Mukherjee
{"title":"Bio-electrochemical response to sense implant degradation","authors":"Jibril Shittu,&nbsp;Maryam Sadeghilaridjani,&nbsp;Mayur Pole,&nbsp;Aditya Ayyagari,&nbsp;Sundeep Mukherjee","doi":"10.1002/mds3.10088","DOIUrl":"10.1002/mds3.10088","url":null,"abstract":"<p>In vivo monitoring of biomedical implants to detect early stages of failure is currently unavailable. State-of-the-art imaging techniques do not provide information about small-scale localized changes in the implant and surrounding environment, which are key to early detection of failure. Here, we discuss different electrochemical responses of implants during degradation which may be utilized to develop biosensors to monitor implant degradation in vivo. This review is focused on identifying the need, potential measurement techniques and degradation response obtained from sensors based on electrochemical signature of biomedical implants. Benefits of designing these novel sensors include continuous monitoring, early failure detection, reduced post-surgery and prevention of catastrophic failure from implant degradation.</p>","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mds3.10088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"112313416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
A novel non-invasive wearable sensor for intraocular pressure measurement 一种新型无创可穿戴式眼压测量传感器
Medical devices & sensors Pub Date : 2020-04-22 DOI: 10.1002/mds3.10086
Angelica Campigotto, Yongjun Lai
{"title":"A novel non-invasive wearable sensor for intraocular pressure measurement","authors":"Angelica Campigotto,&nbsp;Yongjun Lai","doi":"10.1002/mds3.10086","DOIUrl":"10.1002/mds3.10086","url":null,"abstract":"<p>Glaucoma is a chronic eye disease where an increase in intraocular pressure (IOP) permanently damaging the optic nerve leading to irreversible vision loss. Intraocular pressure is the main factor for monitoring the progression of glaucoma and has been found to fluctuate throughout the day. A continuous monitoring system can track the fluctuations in the intraocular pressure throughout the day, improving the management of the disease. A novel non-invasive wearable sensor was created to monitor the fluctuating corneal curvature of the eye and directly relate the deformation to the intraocular pressure. The wearable sensor was able to capture on average 40.8 µm/mmHg with a standard deviation of 29.4 in fluid location per increase in intraocular pressure with an ability to return over 80% back to its original position indicating a good ability to accurately track the fluctuations in the IOP.</p>","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mds3.10086","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47191721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Effect of nanoparticles on surface characteristics of dental nanocomposite 纳米颗粒对牙用纳米复合材料表面特性的影响
Medical devices & sensors Pub Date : 2020-04-20 DOI: 10.1002/mds3.10081
Sepehr Salari, Sara Dadkan, Mehrdad Khakbiz, Mohammad Atai
{"title":"Effect of nanoparticles on surface characteristics of dental nanocomposite","authors":"Sepehr Salari,&nbsp;Sara Dadkan,&nbsp;Mehrdad Khakbiz,&nbsp;Mohammad Atai","doi":"10.1002/mds3.10081","DOIUrl":"10.1002/mds3.10081","url":null,"abstract":"<p>The main purpose of this study is to present a systematically assessment of wear characteristics of hybrid dental composites. Lanthanum oxide (La<sub>2</sub>O<sub>3</sub>) nanofillers are an imperative part of fillers in hybrid dental composites to increase their cosmetic features and radiopacity that are added as a second filler along with quartz microfillers. In this research, hybrid nanocomposite samples are synthesized by different content of La<sub>2</sub>O<sub>3</sub> nanofillers to study their effect on surface behaviour, friction coefficient and wear resistance that further discussed using scanning electron microscopy (SEM) images of the wear track and debris. The results provide a significant influence of nanofillers on wear resistance with samples having higher nanofillers showing lower wear resistance; however, coefficient of friction reaches an optimum and increase with higher content. The wear behaviour is also related to micro-hardness of specimens to find a detailed understanding of wear mechanism.</p>","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mds3.10081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"100489875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Expanded normative data for the balance tracking system modified clinical test of sensory integration and balance protocol 平衡跟踪系统改良版感觉统合与平衡临床测试方案的扩展标准数据
Medical devices & sensors Pub Date : 2020-04-20 DOI: 10.1002/mds3.10084
D. Goble, Elise C. Brown, C. Marks, Harsimran S. Baweja
{"title":"Expanded normative data for the balance tracking system modified clinical test of sensory integration and balance protocol","authors":"D. Goble, Elise C. Brown, C. Marks, Harsimran S. Baweja","doi":"10.1002/mds3.10084","DOIUrl":"https://doi.org/10.1002/mds3.10084","url":null,"abstract":"The modified Clinical Test of Sensory Integration and Balance (mCTSIB) is a popular protocol used to assess key sources of sensory feedback utilized during upright standing. The present study aimed to expand the age range of a previous normative sample of only young adult mCTSIB reference data collected using the Balance Tracking System (BTrackS). In total, 1,276 adults between ages 20 and 59 years old completed the BTrackS mCTSIB protocol in this study. The protocol consisted of four, 20-s trials that systematically manipulated the relative contributions of vision, proprioception and vestibular sensory systems. Total Center of Pressure Path Length results showed that females generally outperformed males in all age groups and sensory conditions. Both sexes showed reduced balance with age that started at age 50–59 years in Standard and Proprioception conditions. In the Vestibular condition, both sexes had reduced balance starting at age 30–39 years. In contrast, the pattern of reduction was different between females and males in the Vision condition. In this case, females showed a decline in balance at age 30–39 years compared to 40–49 years in males. These results provide important information demonstrating sensory feedback processing for balance can decline at differential rates based on age and sex characteristics. Percentile ranking look-up tables were also calculated as a practical tool for researchers and clinicians who regularly perform mCTSIB testing.","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141211065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Current view and prospect: Implantable pressure sensors for health and surgical care 当前观点和前景:用于健康和外科护理的植入式压力传感器
Medical devices & sensors Pub Date : 2020-04-09 DOI: 10.1002/mds3.10068
Yazan Honjol, V. Rajkumar, C. Parent-Harvey, Kaviyanka Selvasandran, S. Kordlouie, Marianne Comeau-Gauthier, Edward J. Harvey, G. Merle
{"title":"Current view and prospect: Implantable pressure sensors for health and surgical care","authors":"Yazan Honjol, V. Rajkumar, C. Parent-Harvey, Kaviyanka Selvasandran, S. Kordlouie, Marianne Comeau-Gauthier, Edward J. Harvey, G. Merle","doi":"10.1002/mds3.10068","DOIUrl":"https://doi.org/10.1002/mds3.10068","url":null,"abstract":"Health monitoring and screening have entered a period of rapid change. Popular terminology refers to this as mobile health (mHealth), which is a direct evolution of eHealth, but is really data-driven technology—sensors oriented for health care. Medical decision support through this technology is the first step towards more personalized and preventative medicine. Pressure is one of the easiest and most interesting physiological parameters to assess whether organs or biological systems are healthy in the body. Pressure recordings are commonly used for clinical diagnosis and monitoring; however, the invasiveness of current technologies and associated risks of infection limit the windows in which data can be gathered. This review discusses the importance of pressure in the body and how monitoring is performed. It also describes newer and commercially available sensors, as well as how they can be im-proved to become minimally invasive, fully wireless pressure sensors for continuous monitoring.","PeriodicalId":87324,"journal":{"name":"Medical devices & sensors","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/mds3.10068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48553677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
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