Journal of rheumatology research最新文献_第5页

Comparison of Sonographic Evaluation of the Median Nerve and Fourth Flexor Tendon Between Asymptomatic Subjects With and Without Diabetes 无症状糖尿病患者与非糖尿病患者正中神经和第四屈肌腱超声评价的比较

Journal of rheumatology research Pub Date : 2019-04-01 DOI: 10.22631/RR.2019.69997.1068

Seyed Hossein Safiabadi-Tali, F. Shirani, A. Haghighi, Nahid Kianmehr, A. Javadzadeh, F. Naderi, Haleh Chehrehgosha, M. Khoshmirsafa

{"title":"Comparison of Sonographic Evaluation of the Median Nerve and Fourth Flexor Tendon Between Asymptomatic Subjects With and Without Diabetes","authors":"Seyed Hossein Safiabadi-Tali, F. Shirani, A. Haghighi, Nahid Kianmehr, A. Javadzadeh, F. Naderi, Haleh Chehrehgosha, M. Khoshmirsafa","doi":"10.22631/RR.2019.69997.1068","DOIUrl":"https://doi.org/10.22631/RR.2019.69997.1068","url":null,"abstract":"Diabetes mellitus (DM) is a common metabolic disease associated with carpal tunnel syndrome (CTS) and tendinopathy. This study aims to assess the ultrasonographic (US) parameters of the flexor tendon and median nerve in asymptomatic subjects with diabetes in comparison with controls without diabetes. 22 DM and 22 non-DM subjects without any symptoms or manipulations in non-dominant hands and wrists were assessed. The ultrasound evaluation of the length, width, cross-sectional area and circumference of forth flexor tendon and the median nerve was performed in the two groups. There was no statistically significant difference of age (P = 0.473) , gender (P = 0.364) , wrist circumferences (P = 0.1921) between the two groups. This study showed no significant difference between the two groups in the median nerve length (P = 0.35), width (P = 0.17), cross-sectional circumference (P = 0.23) and cross-sectional area (P = 0.16). Also, comparing of the sonographic data of the fourth flexor tendon between the two groups presented no significant difference in the length (P = 0.68), width (P = 0.80), cross-sectional circumference (P = 0.70) and cross-sectional area (P = 0.80). In conclusion, our data showed that sonographic values of the median nerve and fourth flexor tendon in asymptomatic subjects with DM did not significantly differ with non-diabetics. These findings demonstrate that still more case studies and more evaluations are required to validate the applicability of ultrasonography in the prediction of carpal tunnel syndrome and tendinopathy in diabetic patients.","PeriodicalId":87314,"journal":{"name":"Journal of rheumatology research","volume":"189 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73777201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relation between Cytokines and Brucella Arthritis, Spondylitis, and Sacroiliitis 细胞因子与布鲁氏菌关节炎、脊柱炎、骶髂炎的关系

Journal of rheumatology research Pub Date : 2019-04-01 DOI: 10.22631/RR.2019.69997.1067

N. Saadati, Mandana Khodashahi, B. Naghibzadeh, Rozita Khodashahi

{"title":"Relation between Cytokines and Brucella Arthritis, Spondylitis, and Sacroiliitis","authors":"N. Saadati, Mandana Khodashahi, B. Naghibzadeh, Rozita Khodashahi","doi":"10.22631/RR.2019.69997.1067","DOIUrl":"https://doi.org/10.22631/RR.2019.69997.1067","url":null,"abstract":"Background and Objectives: Cytokines are produced and secreted from various cells, including T cells. Cytokines play an effective role in the responses elicited by the immune system. As brucella infection cause is an intracellular aerobic rod, cellular immunity has a considerable effect on this disease. The aim of the present study was to evaluate the relation between cytokines and brucellosis arthritis, spondylitis, and sacroiliitis.Materials and Methods: This descriptive case-control study was carried in two tertiary hospitals in Mashhad, Iran in 2010. The study population consisted of a case group, including the patients with the diagnosis of brucella arthritis with lower back pain and a control group, including normal healthy participants. The brucellosis was investigated regarding the history, physical examinations, and serologic examinations. The interferon gamma (IFNγ), interleukin 2 (IL-2), interleukin 4 (IL-4), interleukin 10 (IL-10), and tumor necrosis factor alpha (TNFα) were measured in the serum samples of both groups using enzyme-linked immunosorbent assay technique. Results: The IL-10 had a significant difference in the brucella and control groups (P=0.02). However, IL-2, IL-4, and the TNFα were comparable between brucella and control groups (P=0.1). There was a significant difference between the IFNγ and brucella in the control group (P=0.05). Conclusion: The IFNγ and IL-10 levels were higher in brucella group than those in control group.","PeriodicalId":87314,"journal":{"name":"Journal of rheumatology research","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72790886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comparison between Avocado-Soybean Unsaponifiables and Celecoxib on Serum Levels of Cartilage Oligomeric Matrix Protein in Patients with Knee Osteoarthritis 牛油果-大豆不皂化剂与塞来昔布对膝关节骨性关节炎患者血清软骨寡聚基质蛋白水平的影响

Journal of rheumatology research Pub Date : 2019-04-01 DOI: 10.22631/RR.2019.69997.1069

M. Jokar, H. Azadeh, Z. Mirfeizi, Z. Shariati, K. Hashemzadeh

{"title":"A Comparison between Avocado-Soybean Unsaponifiables and Celecoxib on Serum Levels of Cartilage Oligomeric Matrix Protein in Patients with Knee Osteoarthritis","authors":"M. Jokar, H. Azadeh, Z. Mirfeizi, Z. Shariati, K. Hashemzadeh","doi":"10.22631/RR.2019.69997.1069","DOIUrl":"https://doi.org/10.22631/RR.2019.69997.1069","url":null,"abstract":"Background/objectives: Cartilage oligomeric matrix protein (COMP) as a marker of cartilage destruction. We aimed to compare the effect of a mixture of avocado-soybean unsaponifiables versus celecoxib on the serum level of COMP in patients with knee osteoarthritis.Methods: This was a randomized controlled trial and the patients with knee osteoarthritis were recruited from those who attended Imam Reza Hospital, Mashhad, Iran. The patients were divided randomly into two groups; Group 1 (n=30) received avocado+soybean mixture (300 mg daily) and group 2 (n=30) received celecoxib (200 mg/day) for 2 months. At the enrollment and then every month up to 2 months, the patients' venous blood samples were collected to measure serum COMP.Results: The total number of patients was 60 (male 38%, female 62%) with a mean age 56±7 years. Before treatment, the serum levels of COMP were 14.5±1.4 unit/liter (U/L) and 13.9±1.4 U/L in avocado+soybean mixture and celecoxib groups, respectively (P=0.052). After the first month the serum levels of COMP were 12.3±1.5 U/L and 12.8±1 U/L in avocado+soybean mixture and celecoxib groups, respectively (P","PeriodicalId":87314,"journal":{"name":"Journal of rheumatology research","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85904328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers: A Blind Randomized Controlled Trial. 地尔硫卓凝胶与硝酸甘油软膏在硬皮病手指溃疡愈合过程中的作用:一项盲随机对照试验。

Journal of rheumatology research Pub Date : 2019-04-01 DOI: 10.22631/RR.2019.69997.1065

E. Esmaeilzadeh, M. Nazarinia, S. Shenavandeh

引用次数: 0

Biomechanical properties of heel-pad and metatarsal head soft tissue and foot ulcers in patients with systemic sclerosis – a case control study 系统性硬化症患者脚跟垫和跖骨头部软组织和足部溃疡的生物力学特性-一项病例对照研究

Journal of rheumatology research Pub Date : 2019-04-01 DOI: 10.22631/RR.2019.69997.1066

M. Pourian, I. Mohseni, M. Biglari, M. Sianpanah

{"title":"Biomechanical properties of heel-pad and metatarsal head soft tissue and foot ulcers in patients with systemic sclerosis – a case control study","authors":"M. Pourian, I. Mohseni, M. Biglari, M. Sianpanah","doi":"10.22631/RR.2019.69997.1066","DOIUrl":"https://doi.org/10.22631/RR.2019.69997.1066","url":null,"abstract":"Background: Systemic sclerosis is a chronic disease of connective tissue accompanied with increased risk of foot ulcers. Biomechanical indexes (soft tissue thickness and compressibility) could affect the risk of this phenomenon.Objective: The aim of this study was assessment of heel pad and first metatarsal head soft tissue thickness and compressibility index in scleroderma patients with and without foot ulcers and comparison with healthy individuals.Methods: Heel pad thickness in standing(loaded) and lying(unloaded) positions was measured in 40 scleroderma patients by means of lateral foot radiography. Compressibility index was measured as the ratio of loaded to unloaded thickness. Also, soft tissue thickness of first metatarsal head was measured with ultrasound. Results were compared with 40 healthy controls of matched age and body mass index.Results: Among 40 scleroderma patients (36 females, 4 males) with mean age of 45 (±12) years and mean body mass index of 25.5 (±4) and mean disease duration of 10 years (±9.6), 8 (20%) had foot ulcers. Heel pad thickness (p-value 0.03) and compressibility index (p-value 0.005) in the dominant side and both-sides metatarsal head soft tissue thickness (P-value","PeriodicalId":87314,"journal":{"name":"Journal of rheumatology research","volume":"114 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79198528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Refractory Ocular Behçet’s Disease; Outcome of Low Dose Infliximab 难治性眼病;低剂量英夫利昔单抗的疗效

Journal of rheumatology research Pub Date : 2019-04-01 DOI: 10.22631/RR.2019.69997.1070

N. Ferdous, Nazrul Islam, F. Rahman, Z. Pannu, Fahid Bin Nazrul, A. Zaman, J. Rasker

{"title":"Refractory Ocular Behçet’s Disease; Outcome of Low Dose Infliximab","authors":"N. Ferdous, Nazrul Islam, F. Rahman, Z. Pannu, Fahid Bin Nazrul, A. Zaman, J. Rasker","doi":"10.22631/RR.2019.69997.1070","DOIUrl":"https://doi.org/10.22631/RR.2019.69997.1070","url":null,"abstract":"A 40-year-old woman had been suffering of many symptoms of Behcet’s disease (BD) since her childhood without being diagnosed. She had recurrent mouth ulcers and from the age of 21 vulva ulcers followed by loss of vision due to central retinitis and later also ankle arthritis. At the age of 31, uveitis due to BD was diagnosed. The fact that BD is often not recognized in Bangladesh explains the marked delay in her diagnosis. The initial central retinitis responded well to oral glucocorticoids, azathioprine and cyclosporine, but in the course of time she became refractory to these agents. Considering her financial constraints, low dose Infliximab (3mg/kg) was used resulting in a remarkable but temporal improvement, she came in remission by using 5mg/kg regimen with increased interval time. We summarize the treatment options for ocular involvement in BD patients Conclusions: In countries like Bangladesh diagnosis of Behcet’s disease can be delayed. Early cooperation of dermatologists and eye surgeons with rheumatologists is necessary. Most cases of resistant ocular BD can nowadays be successfully treated with anti TNF-agents. Promising results are published with other biologics for refractory and multi-resistant cases.","PeriodicalId":87314,"journal":{"name":"Journal of rheumatology research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90194629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Massive soft tissue calcifications in a patient with end stage renal disease, complete resolved by Cinacalcet. A case report and review. 终末期肾病患者的大量软组织钙化，经Cinacalcet完全解决。个案报告及检讨。

Journal of rheumatology research Pub Date : 2019-03-01 DOI: 10.22631/RR.2019.69997.1064

F. Espahbodi, M. Mobini, O. Akha

{"title":"Massive soft tissue calcifications in a patient with end stage renal disease, complete resolved by Cinacalcet. A case report and review.","authors":"F. Espahbodi, M. Mobini, O. Akha","doi":"10.22631/RR.2019.69997.1064","DOIUrl":"https://doi.org/10.22631/RR.2019.69997.1064","url":null,"abstract":"Personal non-commercial use only.Rheumatology Research Journal. Copyright © 2019. All rights reserved *Corresponding Author: Maryam Mobini, Rheumatologist, Associate Professor, Diabetes Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Email:mmobini50@yahoo.com, Tel/Fax : (+98)1133350672, (+98)1133264044. Received: 12 June 2018 ; Accepted: 09 December 2018 Metastatic calcification is the deposition of calcium salts in otherwise normal tissue as a severe complication of hemodialysis. It is associated with high levels of serum calcium and phosphorus product. We report a patient on hemodialysis who presented with progressively increasing, tumor-like calcinosis associated with muscle weakness. A 36-year-old male presented with multiple painful masses in different parts of his body that had been progressively increasing for ten months. We investigated and diagnosed him as secondary hyperparathyroidism and metastatic calcification; he was treated with cinacalcet. Given that the increase in parathormone and the onset of bone symptoms in the patient were not synchronous, the need for other markers to be reviewed for bone problems in this hemodialysis patient was confirmed.","PeriodicalId":87314,"journal":{"name":"Journal of rheumatology research","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78657734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Microchimerism on Frequency and Severity of Organ Involve- ment in Iranian Scleroderma Patients 微嵌合对伊朗硬皮病患者器官受累频率和严重程度的影响

Journal of rheumatology research Pub Date : 2019-01-16 DOI: 10.22631/RR.2019.69997.1061

Sepideh Fathi Bitaraf, M. Nazarinia, E. Esmaeilzadeh, E. K. Sarvestani, Zohre Khodamoradi

{"title":"The Effect of Microchimerism on Frequency and Severity of Organ Involve- ment in Iranian Scleroderma Patients","authors":"Sepideh Fathi Bitaraf, M. Nazarinia, E. Esmaeilzadeh, E. K. Sarvestani, Zohre Khodamoradi","doi":"10.22631/RR.2019.69997.1061","DOIUrl":"https://doi.org/10.22631/RR.2019.69997.1061","url":null,"abstract":"Personal non-commercial use only.Rheumatology Research Journal. Copyright © 2019. All rights reserved *Corresponding Author: Mohammad Ali Nazarinia, Geriatric Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, Email: nazariniam@gmail.com, Tel/Fax: (+98) 713-2337855, (+98) 713-2359847 Received: 02 Aguste 2018 ; Accepted: 03 February 2019 Microchimerism is defined as the presence of non-self and circulating cells in a host. The current study aimed to assess the effect of microchimerism on scleroderma major organ involvements. This cross-sectional study was conducted on 56 scleroderma patients registered in a tertiary rheumatology center of Shiraz University of Medical Sciences. Information on the patients’ demographics and disease complications was gathered through a review of medical records. Skin score was applied to better assess skin thickening. High Resolution CT-scan as well as pulmonary function test (PFT) results were also used to investigate pulmonary involvement in patients. Y chromosome serum levels were measured using Phenol Chloroform Extraction protocol and following real-time PCR. Fifty-six scleroderma patients with a mean age of 46±10 years were recruited in this study (58.9% with diffuse scleroderma and 41.07% with limited scleroderma). Other than skin thickening, the most common clinical presentation among the patients was interestitial lung disease (67.8%). No significant difference was found between Y chromosome levels of patients with either lung, cardiac, renal, or gastrointestinal involvement and those who did not have these complications. Y chromosome serum levels based on the results of PFT were also shown to have no significant difference. Moreover, no association was demonstrated between serum Y chromosome and skin score. The serum level of chromosome Y has no impact on the severity and frequency of major organ involvement in Iranian scleroderma patients.","PeriodicalId":87314,"journal":{"name":"Journal of rheumatology research","volume":"126 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87723902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Effects of Personal and Occupational Risk Position on Musculoskeletal Disorders 个人和职业危险部位对肌肉骨骼疾病的影响

Journal of rheumatology research Pub Date : 2019-01-13 DOI: 10.22631/RR.2019.69997.1063

Ahmad Vakili-Basir, Mohammad Gholami-Fesharaki, M. Rowzati, Razieh Maghroori

引用次数: 0

Radiologic hand and wrist changes in systemic sclerosis: Associations with the disease duration, skin score and capillaroscopy 系统性硬化症的手部和腕部影像学改变:与病程、皮肤评分和毛细血管镜检查有关

Journal of rheumatology research Pub Date : 2019-01-01 DOI: 10.22631/rr.2019.69997.1080

S. Sefidbakht, S. Shenavandeh, K. Rasekh, M. Nazarinia

{"title":"Radiologic hand and wrist changes in systemic sclerosis: Associations with the disease duration, skin score and capillaroscopy","authors":"S. Sefidbakht, S. Shenavandeh, K. Rasekh, M. Nazarinia","doi":"10.22631/rr.2019.69997.1080","DOIUrl":"https://doi.org/10.22631/rr.2019.69997.1080","url":null,"abstract":"Objectives Patients with systemic sclerosis (SSc) have some musculoskeletal manifestations. The radiologic manifestations can be articular or non-articular. There is inconsistency in the correlation between clinical manifestations and radiologic changes; there are few reports on the correlation between them and capillaroscopy. Material and Methods We evaluated 81 patients with SSc, using a cross- sectional single center study, referred to scleroderma clinic affiliated to Shiraz University of Medical Sciences, Iran. Skin score and capillaroscopy were performed and an expert radiologist did the radiologic evaluation of the posterior-anterior views of both hands and wrists. For data analysis, SPSS version 19 was used.Results The participants consisted of 73 women and eight men aged 42±2.6 years old. There were 60.5% limited scleroderma (lcSSc) and 39.5% diffuse scleroderma (dcSSc) patients. After 5 years, 91% of them had some radiologic changes mostly asymptomatic.The most common radiologic changes were non-articular (70.1%), including acro-osteolysis, subcutaneous and peri-articular calcinosis and avascular necrosis. Flexion deformities and DIP joint space narrowing were more seen in patients with dcSSc. Resorption of the distal ulna and avascular necrosis was observed more in lcSSc. There was a correlation between radiologic changes and duration, but not with the skin score. The most common capillaroscopic pattern in patients with radiologic change was late scleroderma pattern.Conclusions Radiologic changes which were mostly asymptomatic were common in patients with SSc. The changes were different in patients with dcSSc and lcSSc and there were associations with duration and capillaroscopic patterns, but not with the skin score.","PeriodicalId":87314,"journal":{"name":"Journal of rheumatology research","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79953312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0