Massive soft tissue calcifications in a patient with end stage renal disease, complete resolved by Cinacalcet. A case report and review.

Abstract

Personal non-commercial use only.Rheumatology Research Journal. Copyright © 2019. All rights reserved *Corresponding Author: Maryam Mobini, Rheumatologist, Associate Professor, Diabetes Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Email:mmobini50@yahoo.com, Tel/Fax : (+98)1133350672, (+98)1133264044. Received: 12 June 2018 ; Accepted: 09 December 2018 Metastatic calcification is the deposition of calcium salts in otherwise normal tissue as a severe complication of hemodialysis. It is associated with high levels of serum calcium and phosphorus product. We report a patient on hemodialysis who presented with progressively increasing, tumor-like calcinosis associated with muscle weakness. A 36-year-old male presented with multiple painful masses in different parts of his body that had been progressively increasing for ten months. We investigated and diagnosed him as secondary hyperparathyroidism and metastatic calcification; he was treated with cinacalcet. Given that the increase in parathormone and the onset of bone symptoms in the patient were not synchronous, the need for other markers to be reviewed for bone problems in this hemodialysis patient was confirmed.