Bangladesh Journal of Neuroscience最新文献

{"title":"Sociodemographic and Clinical Factors of Acute Ischemic Stroke","authors":"Md. Amir Hossain, Hannan Ma, K. K. Barman, P. Biswas, M. Jahan, Muhammad Abdul Momen Khan","doi":"10.3329/bjn.v33i1.57464","DOIUrl":"https://doi.org/10.3329/bjn.v33i1.57464","url":null,"abstract":"An observational study was carried out to analyze prevalence of risk factors for ischemic stroke in hospitalized patient in a university hospital. Ninety patients were chosen by using purposive sampling technique. The mean age of patients was 59.01±9.87 years varied from 30 to 75 years and male to female ratio was 1.2:1. Highest incidence of stroke was between the 6th and 7th decade. Patients came from both rural 49 (54.4%) and urban 41 (45.6) area. Most of them belonged to the lower-middle group 70 (84.8%). Regarding education 47 (52.2%) patients had primary level education and 8 (8.9%) patients were illiterate. It was observed that among them current smoker were 30 (33.3%) and ex-smoker 17 (18.9%). It was also observed that 52 (57.8%) patients had hypertension and 32 (35.6%) had diabetes mellitus (DM). Ischemic heart disease was present in 14 (15.6%) patients. By Oxford shire classification of stroke, it was observed that PAC is common 51 (56.7%) among all forms. Majority 38 (42.2%) of patients had hospital stay of 11-15 days. The mean hospital stay was found 13.68±6.6 days. This study found that cigarette smoking, hypertension, diabetes mellitus and ischemic heart diseases are the major risk factors prevalent in our community while other risk factors demand further study.\u0000Bangladesh Journal of Neuroscience 2017; Vol.  33 (1): 18-23","PeriodicalId":8727,"journal":{"name":"Bangladesh Journal of Neuroscience","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77330850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Common Non-Neurological Medical Complications in Acute Ischemic Stroke Patients","authors":"M. Hossain, M. Hannan, P. Biswas, M. Jahan, Mam Khan","doi":"10.3329/bjn.v33i1.57463","DOIUrl":"https://doi.org/10.3329/bjn.v33i1.57463","url":null,"abstract":"Ischemic stroke patients suffer from different complications among which nonneurological medical complications are common along with stroke related neurological complications. This observational study was aimed to find out these non-neurological common medical complications of acute ischemic stroke patients admitted in hospital in this country. This study was conducted by every day observation of acute ischemic stroke patients admitted in the hospital. Medical complications were diagnosed on the basis of clinical features and laboratory findings. In acute ischemic stroke patients, development of medical complications is more common (60%). Among them infective complications were found more than non-infective complications. Urinary tract infections (17.8%), respiratory tract infection (17.8%), mixed complications (13.3%) were found commoner than other complications. Length of hospital stay (LOHS) was prolonged in those patients who developed these complications. These complications play a vital role in outcome of the patients.\u0000Bangladesh Journal of Neuroscience 2017; Vol.  33 (1): 13-17","PeriodicalId":8727,"journal":{"name":"Bangladesh Journal of Neuroscience","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89181631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Etiological Pattern of Dementia in Bangladesh","authors":"Mrk Khan, A. Rizvi, M. Habib, Mk Hasan, A. Mamun, MR Alam, R. Islam","doi":"10.3329/bjn.v32i2.57445","DOIUrl":"https://doi.org/10.3329/bjn.v32i2.57445","url":null,"abstract":"Background: Dementia is a chronic & progressive neurodegenerative disorder affecting usually older people of more than 65 years in which there are disturbances of multiple higher cortical functions including memory, thinking, orientation & others. Dementia patients are increasing in number as the population of older age group is increasing. All types of dementia are treatable, at least with psychosocial interventions. So, accurate diagnosis and evaluation of etiological pattern is essential. \u0000Methods: This cross sectional study was carried out in the Department of Neurology, Bangabandu Sheikh Mujib Medical University, Dhaka, Bangladesh from January 2012 to December 2012 on 88 patients with dementia diagnosed on the basis of mini mental state examination and DSM-IV criteria. \u0000Results: Vascular dementia was the underlying diagnosis in most of the cases (43.3 %) followed by Alzheimers Disease (20.2%) and Parkinson Disease (9%). Other causes were Mixed Dementia, Intracranial Space Occupying Lesion, Post Encephalitic, Hypoxic Encephalitic, Chronic Subdural Haematoma and Tubercular Meningitis. \u0000Conclusion: Vascular dementia is more than Alzheimer’s Dementia in Bangladesh. Multiple vascular risk factors contribute to this. \u0000Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 85-90","PeriodicalId":8727,"journal":{"name":"Bangladesh Journal of Neuroscience","volume":"234 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79641013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adapting Bangla Mini-Mental State Examination (MMSE-B) among Healthy Elderly in Bangladesh","authors":"S. K. Ghose, Kazi Gias Uddin Ahmed, A. Chowdhury, A. Hasan, Muhammad Zillur Rahman Khan, Asm Rezaul Karim, K. Saha, H. Sina, -. Md Arifuzzaman","doi":"10.3329/bjn.v32i2.57446","DOIUrl":"https://doi.org/10.3329/bjn.v32i2.57446","url":null,"abstract":"Background: The aim of our study was to determine whether modified Bangla version (MMSE-B) is as effective as mini mental state examination (MMSE) tool for use in Bangladeshi people. \u0000Methods: This descriptive observational study was carried out in Department of Neurology, DMCH from January 2013 to December 2013. A total 200 healthy adults (patient attendants at the clinic) who met the inclusion criteria, were interviewed using a structured questionnaire containing information on age, sex, residence, educational backgrounds and questions set at MMSE English version (MMSE-E) and modified Bangla version for MMSE-B (Figure-1). MMSE and MMSE-B both were applied in 1:1 ration. The literate people were asked whether they are comfortable to answer in English (MMSE-E) or they would like the translated form and we applied the form of MMSE (MMSE-T) according to their wish. But in other group of people the modified Bangla version (MMSE-B) was used irrespective of level of education. \u0000Result: The mean age at presentation was 58.1±7.8 and 94% were within 50-70 years of age. Male were more common (80, 66) in both the groups and most of them belonging to rural areas. MMSE-B were mostly employed on people having only primary level of education (up to class five, n=80) or no education (n=2), whereas MMSE-E were employed up on people having a level of education higher than class five (n=96). Every question in each item of cognitive domain correlated well (correlation co-efficient range from 0.801- 0.971) except the 7th (correlation co-efficient 0.418) which had higher mean score for MMSE-B than those of MMSE-E (0.90 versus 0.54). The mean score of MMSEB was greater than the mean score of MMSE-E for most of questions except the 1st question that is related to orientation of time. The mean of total score in MMSE-E and MMSE-B were 24.04 and 24.91 respectively with a correlation co-efficient of 0.940. \u0000Conclusion: MMSE-B is adaptable for use in Bangladeshi people irrespective of level of education. \u0000Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 91-97","PeriodicalId":8727,"journal":{"name":"Bangladesh Journal of Neuroscience","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77846984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral Angiographic Study of Anatomical Variations of Anterior Cerebral Artery Complex in Bangladeshi Population","authors":"Md. Amir Hossain, Sharif Uddin Khan, K. Rahman, S. Islam, K. Patwary, Dewan Md Elyas, Muhammad Abdul Momen Khan, S. Dey, MD. Shahidullah, M. Jahan","doi":"10.3329/bjn.v32i2.57441","DOIUrl":"https://doi.org/10.3329/bjn.v32i2.57441","url":null,"abstract":"Background: Anterior cerebral artery is an important terminal branch of internal carotid artery. It forms the anterior component of circle of Willis along with the anterior communicating artery. It is known for the frequent variations. The knowledge of anatomical variations in anterior cerebral artery is of considerable help to clinicians and interventionists. Method: Morphology and variations of the anterior cerebral arteries and the anterior communicating artery were studied in 90 patients undergone digital subtraction angiography (DSA). \u0000Results: Variations were found in 33% (n=30). Variations of the segments in relation with size, course, communications and terminations of the anterior cerebral artery (ACA) were noted. These were divided into different groups like hypoplasia, aplasia, duplication and fenestrations. Hypoplasia/Aplasia of proximal anterior cerebral artery (A1) was 24.5% in right side and 9% in left side. Anterior communicating artery (AComA) was found absent in 9% and fenestration in 9%. Callosomarginal artery was found absent in 2.2% in right side and 4.5% in left side. In right callosomarginal artery 6% had abnormal origin and 3.5% abnormal in left side.Pericallosal artery was present 100% on both sides. Conclusion: Variations of anterior cerebral artery complex anatomy is found common in Bangladeshi population. \u0000Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 56-62","PeriodicalId":8727,"journal":{"name":"Bangladesh Journal of Neuroscience","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87645824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of EEG Changes In Different Types of Clinically Diagnosed Epileptic Patients","authors":"Dhali Sa, Barman Kk, M. Shahidullah, Dey Sk, MR Islam, Mf Islam, M. Alam","doi":"10.3329/bjn.v32i2.57442","DOIUrl":"https://doi.org/10.3329/bjn.v32i2.57442","url":null,"abstract":"Background: Diagnosis of epilepsy is based mainly on clinical history and examination. EEG constitutes the single most valuable laboratory test in the evaluation of patients with epilepsy. Objective: The objective of the present study was to find out the frequency of EEG abnormality among different types of clinically diagnosed epileptic patients. \u0000Methods: This cross-sectional study was carried out in the Department of Neurology, Bangabandhu Sheikh Mujib Medical University, Dhaka. A total of 152 epileptic patients attended in the Epilepsy Clinic, General OPD and EEG room of the Department of Neurology were enrolled for this study. Information on socio-demographic and seizure characteristics was obtained. The records from patients were obtained using the standard data collection form. \u0000Result: Out of 152 epileptic patients male were 62.5% and female were 37.5%, mean age was 20.69 ± 11.83 years. Abnormal EEG was found in 81 (53.3%) patients. Most of the patients 64 (79.0%) had generalized epileptic discharge and 17 (21.0%) had focal epileptic discharge. Out of 81 patients with abnormal EEG wave, 31 (38.3%) patients had spike and wave, 26 (32.1%) patients had sharp wave and 24 (29.6%) patients had multiple types of EEG wave. \u0000Conclusion: The EEG is an important tool for diagnosing an epilepsy syndrome, knowledge of which aids in planning treatment and determining prognosis. \u0000Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 63-67","PeriodicalId":8727,"journal":{"name":"Bangladesh Journal of Neuroscience","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88309639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Creatine Kinase Concentration & Its Association with Severity in Acute Ischemic Stroke Patients: A Cross-Sectional Analytical Study","authors":"MD. Arifuzzaman, Md Rafiqul Islam, S. M. Alam, A. K. Sheikh, Md Shafiqus Saleheen, H. Sina, Muhammad Abdul Momen Khan, A. Begum, M. Rahman, Sukumar Majumdar, H. Rahman","doi":"10.3329/bjn.v32i2.57440","DOIUrl":"https://doi.org/10.3329/bjn.v32i2.57440","url":null,"abstract":"Background: The diagnosis of ischemic stroke remains a clinical one, with confirmatory evidence obtained through neuroimaging. Analogous to the role that the creatine kinase (CK), a biochemical test may be useful in diagnosis as well as detect severity which ultimately helps in the management of acute ischemic stroke. \u0000Objective: To evaluate serum creatine kinase level and its association with severity in acute ischemic stroke patients. \u0000Methods: This cross-sectional analytic study was carried out in the Department of Neurology, BSMMU, Dhaka from January 2014 to December 2014.In this study 50 acute ischemic stroke patients were enrolled as cases. \u0000Result: In this study, 42.0% patients were female and 58% were male and their mean age was 55.96±10.93 years. According to classification by NIH Stroke score, 32% patients was found in minor stroke, 28% in moderate stroke, 26% in moderate to severe stroke and 14% in severe stroke. 80.0% patients had increased level of serum creatine kinase. In this study there is a positive correlation between NIH Stroke Score and Serum creatine kinase level (r= 0.869, p < 0.0001). \u0000Conclusion: Increase severity of acute ischaemic stroke causes increased level of serum creatine kinase. \u0000Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 52-55","PeriodicalId":8727,"journal":{"name":"Bangladesh Journal of Neuroscience","volume":"196 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79893138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case Report on Distal Spinal Muscular Atrophy (SMA)","authors":"H. Rahaman, Md. Rafiqul Islam, Hannan Ma, Maftahul Jannat","doi":"10.3329/bjn.v32i2.57448","DOIUrl":"https://doi.org/10.3329/bjn.v32i2.57448","url":null,"abstract":"Spinal muscular atrophies (SMA) are heterogeneous group of motor system disorders of alpha motor neuron clinically characterized by progressive lower motor neuron features. The distal form of SMA is an extremely rare disorder, which usually presents in the young adults and has a relatively slow progression with almost normal life-span. Differential diagnosis of this syndrome includes hereditary motor sensory neuropathy- Charcot-Marie-Tooth disease (CMT) and distal myopathies, which should be excluded before confirming this rare entity. As distal form of SMA is a very extremely rare condition so we would like to present a young male with this disorder and a short discussion of the theoretical aspects. \u0000Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 106-110","PeriodicalId":8727,"journal":{"name":"Bangladesh Journal of Neuroscience","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82490057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency and Risk Factors of Pneumonia and Urinary Tract Infection during Hospitalization in Acute Stroke Patients.","authors":"Shaheda Ahmad, Matiur Rahman, M. Hosen, A. Kalam, Mohammed Shoab, Md Rafiqul Islam","doi":"10.3329/bjn.v32i2.57444","DOIUrl":"https://doi.org/10.3329/bjn.v32i2.57444","url":null,"abstract":"Background: Acute stroke Patients are at risk of developing a wide range of complications. Among these medical complications the most common are infections, including pneumonia and urinary tract infection (UTI). This study was designed to see the frequency and risk factors of pneumonia and UTI after acute stroke in hospitalized patients. \u0000Methods : This prospective observational study was done in the Department of Neurology and Department of Medicine, Sylhet M.A.G Osmani Medical College Hospital, from May 2014 to November 2014. After hospitalization, a total number of 80 acute stroke patients were enrolled in this study. All patients of both sexes, presented with acute stroke, were confirmed by CT scan of head; vascular risk factors were recorded and relevant investigations were done. \u0000Results: Among the study subjects Urinary tract infection was found in 23 (28.8%) patients. Statistically significant risk factors for UTI were : > 65 years age (OR=2.926; 95% of CI=1.044-8.202; p=0.037). Female gender (OR=0.327; 95% of CI=0.120-0.889; p=0.026), diabetes (OR=2.015; 95% of CI=1.019-7.780; p=0.042), Severe stroke (OR=3.331; 95% of CI=1.217-9.116; p=0.017), Foley tube catheterization (OR=4.229; 95% of CI=1.492-11.982; p=0.005). Pneumonia developed in 17 (21.2%) patients and no pneumonia in 63 (78.8%) patients. \u0000Conclusion : UTI and pneumonia are common occurrence after acute stroke during stroke hospitalization. Older age, female gender, diabetes mellitus, severe stroke at presentation and urinary catheterization were found the risk factors of UTI; whereas older age, severe stroke at presentation, nasogastric tube feeding, oropharyngeal suction and difficulty in swallowing were found the risk factors of pneumonia in acute stroke. \u0000Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 74-84","PeriodicalId":8727,"journal":{"name":"Bangladesh Journal of Neuroscience","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76066000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrophysiological Grading to Assess the Severity of Carpal Tunnel Syndrome in Symptomatic Diabetic Patients","authors":"R. Habib, Dilruba Alam, R. Islam, R. Islam, N. B. Bhowmik, A. Haque","doi":"10.3329/bjn.v32i2.57447","DOIUrl":"https://doi.org/10.3329/bjn.v32i2.57447","url":null,"abstract":"Background: Carpal tunnel syndrome (CTS) is the most frequent compressive focal mononeuropathy found in clinical practice. Patients mostly experience pain, paresthesia, and less commonly, weakness in the median nerve distribution which badly affects dexterity and grip. Common risk factors include repetitive wrist movements, metabolic and degenerative diseases, connective tissue disease and pregnancy. Nerve conduction study is one of the most sensitive and specific tools to diagnose CTS. This study was aimed to grade the CTS cases according to the severity based on electrophysiological findings and explore its association with clinical presentation of diabetic patients had nerve conduction study at BIRDEM General Hospital. Materials and Methods: This observational study was done in the electro diagnostic clinic of Neurology department, BIRDEM during the period Sept 2015 to Feb 2016. The study included 100 hands of 84 patients suffering from CTS consecutively attending the clinic. All the patients were interviewed and clinically examined. Demographic data including age, gender, occupation, affected hand and hand dominance along with duration of disease were recorded. Patients were graded according to clinical history and objective findings and again based on the Canterbury NCS Severity Scale. \u0000Results: Of these 84 diabetic patients presenting with impression of CTS 96% were females. Mean age of the study subjects was 49.6±10.1 (28-85). Most of the female patients were housewives. Clinical grading of CTS was as follows: mild symptoms in 54.76%, moderate symptoms in 23.8% and severe symptoms in 28.58% patients. According to The Canterbury NCS Severity Scale out of total 100 hands,3.5% had Grade 2 (Mild ) 30.5%had Grade 3 (Moderate) ,29.4 % had Grade 4 (Severe), 34.1% had Grade 5 (Very severe) disease. Only 2 patients had Grade 6 (extremely severe) lesion. Of the study subjects 22 (26.19%) had bilateral and rest (73.81%) had unilateral disease. \u0000Conclusion: Data demonstrated female preponderance of the diabetic CTS cases of middle age. Proportional graded deterioration of electrophysiological parameters along with the clinical severity grades highlights the fact that NCS provide additional and independent objective evidence in the diagnosis and severity assessment of CTS and plausibly has important role in prioritizing treatment plan. \u0000Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 98-105","PeriodicalId":8727,"journal":{"name":"Bangladesh Journal of Neuroscience","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82562500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}