Australian Veterinary Journal最新文献

{"title":"Pig carcass decomposition dynamics: Insights into carcass disposal for emergency animal disease management.","authors":"O Schlosberg, B D Cowled, J Torpy, A Höger, R E Thompson, T S Barnes, K Richards, R N Hall, Eec Leslie","doi":"10.1111/avj.13440","DOIUrl":"https://doi.org/10.1111/avj.13440","url":null,"abstract":"<p><p>Australia is free from many economically devastating emergency animal diseases (EADs) that threaten livestock production in neighbouring countries. In Australia, an important consideration for EAD control is managing susceptible feral animal populations, especially in remote and inaccessible areas where carcass disposal poses considerable logistical challenges. One proposed solution is to utilise natural decomposition above ground through the 'destroy and let lie' (D&LL) method, relying on post-mortem changes in carcass temperature and pH to inactivate the EAD agent. We investigated temperature and pH changes in pig carcasses from death until end-stage decomposition at two locations in Queensland to gain insights into how carcasses left in situ decompose under Australian conditions. Using regression modelling, we identified days since humane killing, air temperature, rainfall, relative humidity, anatomical site and study location as significant predictors of carcass pH and temperature. Although the observed carcass pH and temperature conditions did not meet African swine fever virus (ASFV) inactivation thresholds, foot-and-mouth disease virus (FMDV) was likely to be inactivated in the thoracic cavity, superficial and deep skeletal muscle and abdominal cavity of most carcasses. However, FMDV inactivation thresholds were not reached in bone marrow and brain. This suggests that these carcasses may potentially remain infectious with ASFV and FMDV in situ under the experimental conditions encountered, based on the inactivation thresholds selected. Despite this, culling large portions of a feral pig population, in conjunction with D&LL disposal approach, may still support disease control imperatives during an EAD response by reducing live pig numbers and disease transmission.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brucella suis in feral pigs in Australia: what is the risk?","authors":"C C Kneipp, D Marshall, M E Westman, R Malik, M A Stevenson, S M Mor, A K Wiethoelter","doi":"10.1111/avj.13441","DOIUrl":"https://doi.org/10.1111/avj.13441","url":null,"abstract":"<p><p>In Australia, feral pigs (Sus scrofa) are the primary host for Brucella suis. The incidence of B. suis brucellosis in dogs in Queensland (QLD) and New South Wales (NSW) has increased, likely due to hunting and consumption of feral pig meat. This study aimed to update estimates of B. suis seroprevalence and spatial distribution in feral pigs and assess the risk of transmission to dogs. Serology results from 686 feral pigs in QLD and NSW were analysed, with seroprevalence correlated to pig population density. Serology results from 3074 dogs in QLD and NSW were mapped to local government areas (LGAs) and compared with pig density. Raw feral pig meat sold for pet consumption was tested for B. suis. Thirty-seven feral pigs were seropositive, with a survey adjusted true seroprevalence of 17% (95% confidence interval [CI] 12% to 22%) in QLD and 11% (95% CI 8% to 14%) in NSW. No positive spatial autocorrelation between positive and negative pigs was identified. Six hundred dogs from 26 QLD LGAs and 37 NSW LGAs were seropositive, showing a positive association with pig density. Brucella suis DNA was detected in commercially sold feral pig meat. This study found an increased prevalence and geographical expansion of infected pig populations potentially increasing the risk for B. suis transmission. The wide distribution and high level of detection in at-risk dogs highlight the links to pig hunting. Investigating human and dog cases could help identify infected pig populations, enabling hunters to reduce contact with infected pigs in those areas.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of feline infectious peritonitis in cats with molnupiravir: clinical observations and outcomes for 54 cases","authors":"TM Clark,&nbsp;SJ Coggins,&nbsp;R Korman,&nbsp;J King,&nbsp;R Malik","doi":"10.1111/avj.13433","DOIUrl":"10.1111/avj.13433","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the clinical applications and treatment outcomes using molnupiravir for the treatment of naturally occurring feline infectious peritonitis virus (FIPv).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Ninety-two client-owned cats with confirmed or presumptive FIP were retrospectively recruited from 35 veterinary practices, primarily in Australia, between February 2023 and March 2024. Cats were categorised based on treatment received: Cohort A: Molnupiravir treatment: monotherapy, maintenance or rescue therapy; Cohort B: Remdesivir and/or GS-441524 treatment. Seventy-eight cats were enrolled. Molnupiravir was administered orally for a median of 84 days, at a median dose of 13.3 mg/kg BID. Remission was defined as the resolution of FIP-related signs with (i) normalisation of serum globulin concentrations and A:G ratio (≥0.6), or (ii) sustained clinical remission for at least 100 days after stopping anti-viral therapy. Cure rate was defined as the percentage of cats achieving sustained remission, without requiring rescue therapy or experiencing a relapsed disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Molnupiravir monotherapy resulted in a cure rate of 72% (13/18) while molnupiravir maintenance therapy achieved a cure rate of 86% (25/29), and molnupiravir utilised as a rescue therapy achieved a cure rate of 100% (7/7). Treatment with remdesivir/GS-441524 resulted in a cure rate of 71% (17/24 cats). Survival analysis revealed no difference in outcomes between cats treated with molnupiravir monotherapy and those treated with remdesivir/GS-441524. Adverse events associated with molnupiravir therapy included neutropenia, and transient elevations in hepatic enzymes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Molnupiravir demonstrated comparable survival outcomes to remdesivir/GS-441524 for treating FIP and serves as an accessible, effective option across various presentations, including ocular and neurologic forms.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":"103 6","pages":"339-353"},"PeriodicalIF":1.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of complications from perioperative urinary catheterisation in horses","authors":"CT Quinn","doi":"10.1111/avj.13445","DOIUrl":"10.1111/avj.13445","url":null,"abstract":"<p>Catheterisation of the urinary bladder is a common procedure during perioperative care of horses. Benefits of urinary catheters include a reduction in the risk of recovery-associated slip hazards as a consequence of voided urine and the measurement of urine output during anaesthesia. However, there is little information regarding the risks associated with this procedure. A retrospective cohort study was undertaken in horses admitted to a university teaching hospital for surgery during which a urinary catheter was placed perioperatively. Data were retrieved from clinical records including signalment, procedure type, presence of pre-existing urinary/renal pathology, timing of catheter placement, complications from catheterisation, injuries during recovery and total volume of urine. Records were searched for evidence of urinary tract infections (UTI) or urethral strictures at any time following catheterisation. Descriptive statistics were calculated for numerical data. A total of 218 horses were included. The majority of catheters (<i>n</i> = 157, 70.7%) were placed immediately prior to recovery. The median volume of urine collected during anaesthesia was 4.89 mL/kg (0.0–37.66 mL/kg). The duration of catheterisation ranged from less than 20 min to 4 days. Complications occurred in three horses (1.4%) where the catheter could not be passed through the urethra, resulting in minor urethral trauma in one case. No clinical signs of UTI or urethral stricture were reported in any horse post-catheterisation. Short-term placement of urinary catheters during the perioperative period has a low incidence of complications. Difficulty inserting the catheter is occasionally encountered and may result in urethral injury.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":"103 6","pages":"319-321"},"PeriodicalIF":1.3,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/avj.13445","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Australia versus Denmark: an analysis of foot-and-mouth disease mitigation strategies.","authors":"Ajb Wagner, A E Boklund, M P Ward","doi":"10.1111/avj.13435","DOIUrl":"https://doi.org/10.1111/avj.13435","url":null,"abstract":"<p><p>Foot-and-mouth disease (FMD) has progressively increased as an economically significant viral pathogen to the global agricultural and livestock industries, especially in those countries listed as FMD-free, such as Australia and Denmark. The potential risk associated with the loss of this status enlists an equally significant level of biosecurity and outbreak preparedness via specific mitigation strategies. Current technology allows for modelling of theoretical incursion scenarios; however, the parameters used are ever-changing and differ based on location. This study aims to compare the modelling outputs from at least five separate studies, from both Australia and Denmark respectively, to identify the most significant results and subsequently determine the recommendations most important to implement for national FMD outbreak mitigation. The comparative analysis suggests that the demographics, both within and between Australia and Denmark, can markedly affect the spread of FMD, but that each country's modelling of potential FMD outbreaks yielded three common areas for future recommendations: resource allocation and control; economic efficiency; and alternative interventions. Key points of difference, however, were Denmark's island geography and subsequent isolated populations of high-density production that led to a more regional approach of minimising island-island spread through varying vaccination regimes and depopulation/surveillance zone combinations. Australia's strategies of control centred more around enhanced detection and surveillance to prevent the incidence of significant outbreaks in the production animal industry. The most common factor for both was cost, specifically the reduction in time to export post-outbreak, due to each respective export industry, and the significant losses associated with even short periods of trade bans due to disease. The costs of surveillance and resources were similarly investigated in tandem with different interventions to further understand the components of an effective mitigation method for any outbreak of FMD.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative risk assessment for the importation of fresh porcine semen into Australia.","authors":"K Richards, A Pointon, R Cutler","doi":"10.1111/avj.13439","DOIUrl":"https://doi.org/10.1111/avj.13439","url":null,"abstract":"<p><p>The importation of fresh boar semen was qualitatively assessed for the biosecurity risk of introducing specific diseases into the Australian pig herd. The methodology used was as described by the World Organisation for Animal Health (WOAH) and applied for official import risk assessments undertaken by Australia. It was found that the risk of introducing porcine reproductive and respiratory syndrome virus, Senecavirus A, porcine epidemic diarrhoea virus and African swine fever virus exceeded Australia's appropriate level of protection even when WOAH mitigations were applied. Findings of the assessment also support predictions of new diseases transmitted via semen emerging that may cause serious and/or irreversible harm to the Australian pig industry.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vale Peter Gregor Scott","authors":"J Schröder,&nbsp;G Reed,&nbsp;S Page,&nbsp;A Irving","doi":"10.1111/avj.13443","DOIUrl":"10.1111/avj.13443","url":null,"abstract":"","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":"103 5","pages":"304"},"PeriodicalIF":1.3,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opportunistic sampling from the near-threatened Alexandrine parakeet uncovers genomes of a novel parvovirus and beak and feather disease virus.","authors":"S Sarker, N Klukowski, S Talukder, A Athukorala, M J Uddin","doi":"10.1111/avj.13442","DOIUrl":"https://doi.org/10.1111/avj.13442","url":null,"abstract":"<p><p>Birds are known to harbour a wide range of pathogenic viruses, including the beak and feather disease virus (BFDV; species, Circovirus parrot), which poses a significant threat to the conservation of endangered avian species. This study reports the genomic identification and characterisation of a novel psittaciform chaphamaparvovirus (PsChPV-6) and BFDV, sequenced from the faecal samples of healthy Alexandrine parakeets (Psittacula eupatria). PsChPV-6 is a linear, single-stranded DNA virus consisting of 4232 nucleotides (nt) with a high A + T content and five predicted open reading frames (ORFs). Key proteins encoded by PsChPV-6, such as the nonstructural protein 1 (NS1) and major capsid protein VP1, demonstrate strong sequence similarities to other avian parvoviruses, with conserved motifs in NS1 crucial for viral replication. The presence of a previously uncharacterised ORF1 region suggests strain-specific viral features that warrant further exploration. BFDV is a circular single-stranded DNA virus in the Circoviridae family and was also identified in the samples. Phylogenetic analysis positioned PsChPV-6 within the Chaphamaparvovirus genus, closely related to parvoviruses from diverse avian species, whereas BFDV was grouped with strains from Australian cockatoos and other nonpsittacine birds, suggesting potential cross-species transmission. These findings contribute to a deeper understanding of the genetic diversity and evolutionary dynamics of these viral pathogens in bird populations, underscoring the importance of ongoing surveillance to evaluate their ecological and veterinary impacts.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myelopathy caused by Cladophialophora bantiana in a dog and a cat","authors":"L McLeay,&nbsp;P Kenny,&nbsp;G Child,&nbsp;SL Donahoe,&nbsp;E Jenkins,&nbsp;A Taylor,&nbsp;A Lam,&nbsp;P Martin,&nbsp;M Krockenberger","doi":"10.1111/avj.13436","DOIUrl":"10.1111/avj.13436","url":null,"abstract":"<p><i>Cladophialophora bantiana</i> is a neurotropic phaeohyphomycotic fungal organism. The most common neural manifestation of <i>C. bantiana</i> infection is brain abscessation or systemic phaeohyphomycosis. This is the first report of spinal cord dysfunction as the presenting clinical manifestation of this disease in dogs and cats. This report describes two cases of myelopathy caused by <i>C. bantiana</i> infection in a dog and a cat. Case 1, a 10-month-old male entire Cavalier King Charles Spaniel (CKCS) was presented for acute onset tetraparesis and cervical pain. Magnetic resonance imaging identified a focal, rim contrast-enhancing intramedullary lesion in the cervical spinal cord. The dog was treated empirically with antibiotics and corticosteroids but clinically deteriorated and was humanely euthanased. Polymerase chain reaction (PCR) of tissue samples of the lesion collected via post-mortem examination identified <i>C. bantiana.</i> Case 2, a 4-year-old male neutered domestic short hair cat, was presented with non-ambulatory paraparesis. The cat was humanely euthanased, and post-mortem examination revealed severe osteomyelitis of the 12th thoracic vertebral lamina, causing spinal cord compression and degeneration. Lesions were also found in the kidneys, spleen and lungs. Fungal hyphae were identified in the urine, and panfungal PCR and sequencing of the fungus cultured from tissue samples identified <i>C. bantiana</i>. These cases demonstrate two manifestations by which <i>C. bantiana</i> infection may cause spinal cord dysfunction: pyogranulomatous myelitis or vertebral osteomyelitis causing spinal cord compression and degeneration. The route of infection is unknown in both cases; however, it is considered most likely via inhalation of fungal spores or inoculation of wounds.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":"103 6","pages":"332-338"},"PeriodicalIF":1.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a tibial osseointegrated prosthesis as a limb salvage method in two dogs","authors":"A Fink,&nbsp;A Malak,&nbsp;M Al Muderis,&nbsp;W Lu,&nbsp;AS Levien","doi":"10.1111/avj.13438","DOIUrl":"10.1111/avj.13438","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To report on the management and outcomes of two dogs treated with osseointegrated prosthesis for pelvic-limb salvage.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>Short case series.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Sample Population</h3>\u0000 \u0000 <p>Two client-owned large breed dogs with distal tibial amputation due to neonatal and iatrogenic trauma.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Preoperative computed tomography (CT) was performed to assess tibial medullary length and width. A custom-made intramedullary prosthesis was implanted and attached to a 3D-printed external prosthesis simulating a foot. Postoperative care included bandaging and regular chlorhexidine washes. Postoperative monitoring included clinical evaluation, owners’ assessment of function and radiographs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Both dogs regained good use of the operated limb within 3 weeks of surgery. Osseointegration and bone remodelling around the implants were noted on radiographs, with no evidence of loosening or implant migration observed. Mild serosanguinous discharge at the cutaneous–implant interface was observed in the early postoperative period, resolving without intervention. Progressive osteolysis around the implants was detected on radiographs in both dogs by 22 months. Though osteomyelitis is suspected, both dogs were using the limb adequately and had satisfactory quality of life at more than 36 months after surgery. A consistent hygiene routine is suspected to delay this process and should theoretically prolong the lifespan of these implants.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This osseointegrated implant system allowed dogs with traumatic loss of the hindpaw to regain normal clinical function of their pelvic limb for 3 years. Occasional soft tissue infections of the stoma sites were observed, but were easily managed, and long-term (36 month) follow-up suggests durability of the prosthesis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>These results justify further studies in a larger cohort to assess the long-term durability of osseointegrated prostheses as a single-stage strategy to treat partial limb amputation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":"103 6","pages":"368-376"},"PeriodicalIF":1.3,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}