A Teh, J Robertson, S L Donahoe, T Crighton, S Boyd, R Malik
{"title":"Atypical presentation of disseminated mycobacteriosis due to Mycobacterium avium in an aged cat.","authors":"A Teh, J Robertson, S L Donahoe, T Crighton, S Boyd, R Malik","doi":"10.1111/avj.13410","DOIUrl":"https://doi.org/10.1111/avj.13410","url":null,"abstract":"<p><p>In cats, mycobacteriosis tends to present in a syndromic manner, with cases either being due to tuberculosis (TB) (in countries where TB is endemic), one of the \"leprosy-like\" diseases affecting the skin and subcutis, panniculitis caused by infection of subcutaneous tissues generally with rapidly growing Mycobacteria spp. or widely disseminated granulomatous disease, which is usually caused by members of the Mycobacterium avium-intracellulare complex (MAC). Disseminated MAC disease is rare, but when it occurs, usually develops in immunocompromised hosts with defective cell-mediated immunity. This report describes a case of widely disseminated mycobacteriosis in a 10-year-old American Shorthair cat with an atypical multi-organ distribution including rarely documented thyroid gland involvement. The cat presented for a chronic history of inappetence and weight loss. Abdominal ultrasonography revealed a large mass on the left kidney, and an aspirate (FNA) from this mass showed abundant negative-staining bacilli which were confirmed to be acid-fast with Ziehl-Neelsen (ZN) staining. This was consistent with a mycobacterial aetiology. Necropsy revealed mycobacterial granulomas and/or granulomatous inflammation in the kidneys, thyroid gland, liver, spleen, lungs and left mandibular lymph node, with abundant intralesional acid-fast bacilli in all these tissues. Polymerase chain reaction (PCR) and culture on samples of all affected tissues were positive for M. avium. Collectively, the findings are consistent with disseminated mycobacteriosis due to M. avium with atypical distribution of lesions. Very likely, the cat had underlying immunodeficiency of undetermined cause, exacerbated by the administration of depot corticosteroid.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R O Bowater, T Mackie, J Picard, I Huisman, L Hayes, J D Taylor
{"title":"Clinicopathological findings of melioidosis in captive red-legged pademelons (Thylogale stigmatica) in northern Queensland, Australia.","authors":"R O Bowater, T Mackie, J Picard, I Huisman, L Hayes, J D Taylor","doi":"10.1111/avj.13403","DOIUrl":"https://doi.org/10.1111/avj.13403","url":null,"abstract":"<p><strong>Background: </strong>Melioidosis, caused by Burkholderia pseudomallei, is an important disease that is endemic in areas of northern Australia and can cause a wide range of clinical signs in people and animals. There is limited published data on the disease in marsupials.</p><p><strong>Case report: </strong>Two captive red-legged pademelons (Thylogale stigmatica) with collective signs of lethargy, dysphagia and bloody oral discharge were submitted for necropsy and showed variations in pathology findings ranging from multifocal abscessation in various tissues to evidence of fulminant septicaemia. In both cases Burkholderia pseudomallei was confirmed by bacterial culture and qPCR.</p><p><strong>Conclusion: </strong>This report details the first report of melioidosis in captive red-legged pademelons (Thylogale stigmatica) and describes the variations in clinical signs and pathological findings that were encountered with the disease. More research is needed to better understand melioidosis in marsupials to aid clinicians in making a prompt diagnosis.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of two rhinoplasty techniques combined with vestibuloplasty on the cross-sectional area of the rostral nasal cavity in brachycephalic dogs with stenotic nares.","authors":"K Shimura, C D Franklin, A K House","doi":"10.1111/avj.13404","DOIUrl":"https://doi.org/10.1111/avj.13404","url":null,"abstract":"<p><strong>Objective: </strong>To compare preoperative and postoperative cross-sectional areas (CSAs) of the external nares and nasal vestibule on computed tomography (CT) transverse sections in brachycephalic dogs that underwent a vestibuloplasty in combination with either a Trader's technique or vertical wedge resection rhinoplasty.</p><p><strong>Methods: </strong>Medical records and corresponding preoperative and postoperative head computed tomographic images were reviewed to measure CSA at two defined points on transverse sections of the nasal cavities.</p><p><strong>Results: </strong>Nine brachycephalic dogs were included for analysis. Trader's technique and vestibuloplasty were performed in five dogs. Vertical wedge resection and vestibuloplasty were performed in four dogs. CSAs were significantly increased in all rostral nasal cavities postoperatively in both combination of techniques. The mean difference in CSA of the right and left external nares were 37.12 mm<sup>2</sup> (95% confidence interval [CI] 24.59, 49.66) and 64.3 mm<sup>2</sup> (95% CI 28.78, 60. 04), respectively. The mean difference in CSA of the right and left nasal vestibules were 25.08 mm<sup>2</sup> (95% CI 11.44, 38.73) and 28.73 mm<sup>2</sup> (95% CI 11.83, 45.64), respectively.</p><p><strong>Clinical significance: </strong>Vestibuloplasty in combination with either Trader's technique or vertical wedge resection significantly increased the CSA of the external nares and nasal vestibules. These techniques did not result in recurrent stenosis or collapse of the alar wings in all evaluated rostral nasal cavities in this case series.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serovar Australis replaces serovar Copenhageni as the most common cause of canine leptospirosis in New South Wales, Australia.","authors":"C Griebsch, N Kirkwood, M P Ward, J M Norris","doi":"10.1111/avj.13401","DOIUrl":"https://doi.org/10.1111/avj.13401","url":null,"abstract":"<p><p>Highly fatal canine leptospirosis emerged in urban Sydney dogs in 2017, and serovar Copenhageni, against which a registered monovalent vaccine is available, was predominant until 2020. This study was conducted to (1) determine serological characteristics of canine leptospirosis in New South Wales (NSW) between 2021 and 2023; (2) describe the geospatial distribution of leptospirosis; and (3) evaluate if clinicopathological abnormalities and outcome differ between the dominant infecting serovars, Copenhageni versus Australis. Cases were identified through referral or direct veterinarian contact and included if clinical and clinicopathological findings confirmed leptospirosis. Between 2021 and 2023 leptospirosis was confirmed in 61 dogs in NSW. In 2022 two major outbreaks occurred in the local government areas of Shoalhaven (n = 23) and Lake Macquarie (n = 7). The most common serovar identified by microscopic agglutination test (MAT) was Australis (n = 23) followed by Copenhageni (n = 8), Pomona (n = 2), Robinsoni (n = 2) and Bratislava (n = 1). In 16/18 cases from Shoalhaven in which serological results were available, serovar Australis was identified. Dogs infected with serovar Copenhageni were significantly (P < 0.05) more likely to have hepatic involvement with significantly higher liver enzyme activities, bilirubin concentration and icterus, whereas dogs with serovar Australis were significantly (P < 0.01) more likely to have glucosuria. Overall case fatality rate was 40% and was not different between infecting serovars. There are regional differences of infecting serovars with distinct leptospirosis hotspots, and differences in clinicopathological findings. The apparent emergence of serovar Australis highlights the need for bi- or multivalent vaccines and ongoing case surveillance of causal serovars is needed. Glucosuria should prompt leptospirosis testing in endemic areas.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ranald David Alan Cameron.","authors":"R Fogarty","doi":"10.1111/avj.13407","DOIUrl":"https://doi.org/10.1111/avj.13407","url":null,"abstract":"","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multifocal nodular facial disease in a 5-year-old Whippet cross dog.","authors":"B J Pullens, B Remaj, B A Hedgespeth","doi":"10.1111/avj.13397","DOIUrl":"https://doi.org/10.1111/avj.13397","url":null,"abstract":"<p><p>This case report describes a mycobacterial infection in an adult Whippet cross dog. The dog was diagnosed with Mycolicibacterium sediminis infection, a species of mycobacteria that is yet to be reported as a causative agent of infection in humans or domestic animals. The dog was presented for specialist opinion of a 6-month history of severe facial lymphadenopathy that was nonresponsive to antibiotic and immunosuppressive therapy. A necrotic lesion developed on her right antebrachium approximately 10-14 days before presentation. The dog was anaesthetised for computed tomography and nodule and skin biopsies including fresh tissue for mycobacterial polymerase chain reaction (PCR). The nodules contained pyogranulomatous inflammation and perivascular necrosis that are typically found in mycobacterial infections. The mycobacterial PCR isolated Mycolicibacterium sediminis. The dog was prescribed triple antibiotic therapy and tapered off corticosteroids, with noticeable improvement within 4 weeks and resolution of granulomas within 3 months of therapy. Presence of chronic dermal pyogranulomatous inflammation should raise suspicions for mycobacterial disease, and fresh tissue should be submitted for PCR to aid in diagnosis.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rectal mast cell tumour in a dog with lower grade features of biological aggressiveness.","authors":"Lyc Tay, L Brockley","doi":"10.1111/avj.13402","DOIUrl":"https://doi.org/10.1111/avj.13402","url":null,"abstract":"<p><p>An 8-year-old, neutered female, Australian Silky Terrier presented to her primary veterinarian with non-specific clinical signs of general unwellness, shaking, lethargy, inappetence and no defecation for 2-3 days. A rectal mass was found on physical examination. The rectal mass was surgically resected and histopathology was consistent with a mast cell tumour (MCT) with a mitotic count of 0 per 2.37mm<sup>2</sup>. The dog had follow-up chemotherapy protocol comprising of vinblastine and prednisolone and was doing well with no evidence of tumour recurrence 30 weeks post surgical resection and is still alive and clinically normal at the time of writing, 9 months post initial diagnosis. Primary MCTs of the gastrointestinal tract have previously been reported to be associated with a poor prognosis. This is the first report of a canine rectal mast cell tumour with lower grade features of biological aggressiveness and a possibly more favourable prognosis compared with the current published literature.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Horner, G F Agne, D P Byrne, M E Bain, B M Lynch, W R Gow, E-Ljmm Verdegaal
{"title":"Case series report: Equine coronavirus in Australia.","authors":"S Horner, G F Agne, D P Byrne, M E Bain, B M Lynch, W R Gow, E-Ljmm Verdegaal","doi":"10.1111/avj.13392","DOIUrl":"https://doi.org/10.1111/avj.13392","url":null,"abstract":"<p><strong>Background: </strong>Equine Coronavirus (ECoV) can cause gastrointestinal disease and was first described in 2000 in the USA followed by several international outbreak case reports. Disease manifestation is characterised by vague clinical signs, including mild pyrexia, lethargy and anorexia. Morbidity ranges greatly from 10% to 83%. Although uncommon, ECoV may result in death secondary to disruption to the gastrointestinal barrier causing endotoxaemia and hyperammonaemic encephalopathy. Unfortunately to date, there is no vaccine available to prevent ECoV.</p><p><strong>Case reports: </strong>Three faecal quantitative polymerase chain reaction (qPCR)-positive ECoV cases are described that presented with mild to severe colic signs: a 2-year-old Miniature Pony gelding from South Australia, an 8-year-old Arabian Riding Pony gelding, and a 6-year-old Warmblood mare, both from Western Australia. The diagnosis was based on a positive faecal qPCR, which is currently the gold standard diagnostic tool. All horses in this case series survived after medical management. The Miniature Pony presented with anorexia and mild colic signs. On day 5, the pony revealed severe colic signs unresponsive to analgesia along with severe abdominal distension secondary to caecal distension requiring surgical intervention.</p><p><strong>Conclusion: </strong>To the authors' knowledge, this case series is the first published report of ECoV cases in Australia, and it adds both to the clinical description of the disease in horses and to the differential diagnosis list of colic signs.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A retrospective analysis of clinical features, management and outcomes in dogs and cats with Eastern Brown Snake envenomation (2016-2022).","authors":"S K Day, K J Nash, M J Midwinter, W A Goodwin","doi":"10.1111/avj.13399","DOIUrl":"https://doi.org/10.1111/avj.13399","url":null,"abstract":"<p><p>Australian Eastern brown snakes (Pseudonaja textilis) can cause venom-induced consumptive coagulopathy (VICC) in envenomated dogs and cats due to toxin-induced consumption of clotting factors. The objective of this study was to describe presenting clinical signs, prevalence of VICC and haemorrhage, VICC resolution timelines and patient outcomes in a population of dogs and cats with Eastern brown snake envenomation (EBSE). Data from dogs and cats presenting with EBSE were retrospectively evaluated. Univariable and multivariable analyses were performed to test predictor variable effects on outcomes. Animals who were euthanased for financial reasons on presentation were excluded from treatment and outcome analysis. Two-hundred and forty dogs and 98 cats were included. On presentation, 66% (159/240) of dogs had lower motor neuropathy (LMN), 31% (74/240) had preparalytic collapse and 30% (72/240) had signs of haemorrhage. In cats, 94% (92/98) had LMN, and only 5% (5/98) had haemorrhage. Ninety-two percent of dogs (209/226) and cats (81/88) were diagnosed with VICC on presentation and median time to normalisation of coagulation tests was 24 hours. Median hospitalisation length was 1.5 days for dogs (lower quartile [LQ]-upper quartile [UQ]: 1.0-3.0) and 2 days for cats (LQ - UQ: 1.0-2.5). Dogs presenting with LMN and no history of preparalytic collapse had significantly longer hospitalisation times (median 2.25 vs. 1.0 days, P-value <0.001; median 2.0 vs. 1.0 days, P-value <0.001 respectively). Odds of survival was lower in dogs with LMN (odds ratio [OR]: 0.23) and in the pooled multivariable analysis of dogs and cats with haemorrhage (OR: 0.39). The administration of antivenom overall was found to confer a survival advantage; however analysis failed to show increased odds of survival with administration of more than 4000 units. Overall, 89% (187/210) of dogs and 75% (58/77) of cats survived to discharge.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How do Australian veterinarians perceive professional conduct in their profession?","authors":"Q Huang, I Van Gelderen","doi":"10.1111/avj.13400","DOIUrl":"https://doi.org/10.1111/avj.13400","url":null,"abstract":"<p><strong>Objective: </strong>Professional skills required for meeting standards of veterinary professional conduct demanded by the public, colleagues and the community are recognised as being equally important to the technical skills required of a veterinarian. To reflect current standards in the profession, this project describes how Australian veterinarians perceive aspects of veterinary professional conduct.</p><p><strong>Methods: </strong>Using an anonymous survey, opinions of Australian veterinarians were sought on perceptions of importance of professional conduct criteria derived from the eight standards listed in the Australian Veterinary Association's Code of Professional Conduct. Participants rated the importance of 15 statements on a six-point Likert scale. Univariable analysis of 98 completed responses was conducted where impacts of age, gender, career stage and the industry on the dependent variable (response to each statement) were evaluated using ordinary logistic regression analysis in R studio where odd ratios (ORs) were determined, and significance was at P < 0.05.</p><p><strong>Results: </strong>The statement revealing the highest mean score with respect to perceived importance was 'that veterinarians hold the health, welfare and respectful treatment of animals as a key concern'. Results indicated high levels of consensus with nine of 15 statements revealing no significant differences based on age, gender, career stage, and for all statements no significant difference based on nature of work. Six statements demonstrating significant differences were based on either gender, age or career stage.</p><p><strong>Conclusions: </strong>This study provides insights into how Australian veterinarians perceive professional conduct. Results provide an aid for future study development and contribute to the discussion of veterinary professionalism.</p>","PeriodicalId":8661,"journal":{"name":"Australian Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}